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Mutation Report for: Y72N/Y124Q/W286A/F295L/F297V/Y337A/V407F_human-ACHE

Y72N/Y124Q/W286A/F295L/F297V/Y337A/V407F_human-ACHE
Gene_Locus|human-ACHE
Mode of mutation|Site directed mutagenesis
Amino Acid change|Y72N/Y124Q/W286A/F295L/F297V/Y337A/V407F
Torpedo number|70//121//279//288//290//330//400//70,121,279,288,290,330,400
Summary|
Comment|p.Tyr72Asn/Tyr124Gln/Trp286Ala/Phe295Leu/Phe297Val/Tyr337Ala/Val407Phe
Kinetic parameters|none


References:
    Title: The aromatic trapping of the catalytic histidine is essential for efficient catalysis in acetylcholinesterase
    Barak D, Kaplan D, Ordentlich A, Ariel N, Velan B, Shafferman A
    Ref: Biochemistry, 41:8245, 2002 : PubMed

            




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