Paper Report for: Tucek_1998_J.Physiol.Paris_92_241
Reference
Title: Positive effects of allosteric modulators on the binding properties and the function of muscarinic acetylcholine receptors Tucek S, Jakubik J, Dolezal V, El-Fakahany EE Ref: Journal de Physiologie (Paris), 92:241, 1998 : PubMed
Data are reviewed indicating that allosteric modulators can enhance the affinities of muscarinic receptors for their antagonists and agonists, that the enhancement of the affinity for agonists is relevant functionally, and that the allosterically induced conformational change also affects the interaction between the receptors and the G proteins.
        
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Tucek S, Jakubik J, Dolezal V, El-Fakahany EE (1998) Positive effects of allosteric modulators on the binding properties and the function of muscarinic acetylcholine receptors Journal de Physiologie (Paris)92: 241-3
Tucek S, Jakubik J, Dolezal V, El-Fakahany EE (1998) Journal de Physiologie (Paris)92: 241-3