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Reactivator Report for: TAB2OH

ability to reactivate VX-BChE is 2.6-fold higher than those ofpralidoxime, but it less efficient than pralidoxime for OP-inhibited AChE (23-fold less efficient for VX-inhibited AChE, 9.5-fold less efficient for tabun-AChE, and 2.7-fold less efficient for paraoxon-inhibited AChE)


General
Type Oxime, Pyridine-aldoxime, Benzaldehyde
Chemical_Nomenclature 2-Trimethylanilinium-6-hydroxy-benzaldehyde oxime chloride
Canonical SMILES C1(=C(C(=CC=C1)[N+](C)(C)C)C=NO)O.[Cl-]
InChI InChI=1S/C10H14N2O2.ClH/c1-12(2,3)9-5-4-6-10(13)8(9)7-11-14;/h4-7H,1-3H3,(H-,11,13,14);1H
InChIKey IFAHSGDOMJKJLI-UHFFFAOYSA-N
Other name(s)
________________________________________________________________________________________________
MW|230.69
Formula|C10H15ClN2O2
CAS_number|
PubChem|
UniChem|IFAHSGDOMJKJLI-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target

References:
Search PubMed for references concerning: TAB2OH
    Title: Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes
    Radic Z, Dale T, Kovarik Z, Zunec S, Garcia E, Zhang LM, Amitai G, Green C, Radic B and Taylor P <3 more author(s)>
    Ref: Biochemical Journal, 450:231, 2013 : PubMed

            


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