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4UUQ

Name : Crystal structure of human mono-glyceride lipase in complex with SAR127303

Revelation date : 21-Jan-2015

Family : Monoglyceridelipase_lysophospholip

Gene_locus : human-MGLL

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Griebel, G., Pichat, P., Beeske, S., Leroy, T., Redon, N., Francon, D., Bert, L., Even, L., Lopez-Grancha, M., Tolstykh, T., Sun, F., Yu, Q., Brittain, S., Arlt, H., He, T., Zhang, B., Wiederschain, D., Bertrand, T., Houtman, J., Rak, A., Vallee, F., Michot, N., Auge, F., Menet, V., Bergis, O.E., George, P., Avenet, P., Mikol, V., Didier, M., Escoubet, J.

Ligand :

References (2)

Title : Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents - Griebel_2015_Sci.Rep_5_7642
Author(s) : Griebel G , Pichat P , Beeske S , Leroy T , Redon N , Jacquet A , Francon D , Bert L , Even L , Lopez-Grancha M , Tolstykh T , Sun F , Yu Q , Brittain S , Arlt H , He T , Zhang B , Wiederschain D , Bertrand T , Houtmann J , Rak A , Vallee F , Michot N , Auge F , Menet V , Bergis OE , George P , Avenet P , Mikol V , Didier M , Escoubet J
Ref : Sci Rep , 5 :7642 , 2015
Abstract : Griebel_2015_Sci.Rep_5_7642
ESTHER : Griebel_2015_Sci.Rep_5_7642
PubMedSearch : Griebel_2015_Sci.Rep_5_7642
PubMedID: 25560837
Gene_locus related to this paper: mouse-ABHD6

Title : Structural basis for human monoglyceride lipase inhibition - Bertrand_2010_J.Mol.Biol_396_663
Author(s) : Bertrand T , Auge F , Houtmann J , Rak A , Vallee F , Mikol V , Berne PF , Michot N , Cheuret D , Hoornaert C , Mathieu M
Ref : Journal of Molecular Biology , 396 :663 , 2010
Abstract : Bertrand_2010_J.Mol.Biol_396_663
ESTHER : Bertrand_2010_J.Mol.Biol_396_663
PubMedSearch : Bertrand_2010_J.Mol.Biol_396_663
PubMedID: 19962385
Gene_locus related to this paper: human-MGLL

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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