5BV7

Name : Crystal structure of human LCAT (L4F, N5D) in complex with Fab of an agonistic antibody

Revelation date : 16-Dec-2015

Family : PC-sterol_acyltransferase

Gene_locus : human-LCAT

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Piper, D.E., Romanow, W.G., Thibault, S.T., Walker, N.P.C.

Ligand :

References (1)

Title : Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism - Gunawardane_2016_J.Biol.Chem_291_2799
Author(s) : Gunawardane RN , Fordstrom P , Piper DE , Masterman S , Siu S , Liu D , Brown M , Lu M , Tang J , Zhang R , Cheng J , Gates A , Meininger D , Chan J , Carlson T , Walker N , Schwarz M , Delaney J , Zhou M
Ref : Journal of Biological Chemistry , 291 :2799 , 2016
Abstract : Gunawardane_2016_J.Biol.Chem_291_2799
ESTHER : Gunawardane_2016_J.Biol.Chem_291_2799
PubMedSearch : Gunawardane_2016_J.Biol.Chem_291_2799
PubMedID: 26644477
Gene_locus related to this paper: human-LCAT

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

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