6T2H
Name : Furano[2,3-d]prymidine amides as human Notum inhibitors 1 (M9N)
Revelation date : 01-Jan-2020
Family : Pectinacetylesterase-Notum
Gene_locus : human-NOTUM
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Zhao, Y., Jones, E.Y.
Ligand :
References (1)
| Title : Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors - Atkinson_2019_Bioorg.Med.Chem.Lett__126751 |
| Author(s) : Atkinson BN , Steadman D , Mahy W , Zhao Y , Sipthorp J , Bayle ED , Svensson F , Papageorgiou G , Jeganathan F , Frew S , Monaghan A , Bictash M , Jones EY , Fish PV |
| Ref : Bioorganic & Medicinal Chemistry Lett , :126751 , 2019 |
| Abstract : Atkinson_2019_Bioorg.Med.Chem.Lett__126751 |
| ESTHER : Atkinson_2019_Bioorg.Med.Chem.Lett__126751 |
| PubMedSearch : Atkinson_2019_Bioorg.Med.Chem.Lett__126751 |
| PubMedID: 31862412 |
| Gene_locus related to this paper: human-NOTUM |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
