Ala-Pro-AFC
General
Type : Peptide || Coumarin || Trifluoro || Pyrrolidine || Carboxamide
Chemical_Nomenclature : 1-(2-aminopropanoyl)-N-[2-oxo-4-(trifluoromethyl)chromen-7-yl]pyrrolidine-2-carboxamide
Canonical SMILES : CC(C(=O)N1CCCC1C(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C(F)(F)F)N
InChI : InChI=1S\/C18H18F3N3O4\/c1-9(22)17(27)24-6-2-3-13(24)16(26)23-10-4-5-11-12(18(19,20)21)8-15(25)28-14(11)7-10\/h4-5,7-9,13H,2-3,6,22H2,1H3,(H,23,26)
InChIKey : GGRRKBLWOMKWNS-UHFFFAOYSA-N
Other name(s) : D-Ala-Pro-AFC, H-Ala-Pro-AFC, AP-AFC, D-AP-AFC, Ala-Pro-7-Amino-4-trifluoromethylcoumarin, D-Ala-Pro-7-Amino-4-trifluoromethylcoumarin
MW : 397.34
Formula : C18H18F3N3O4
CAS_number :
PubChem :
UniChem :
Iuphar :
Target
Families : Prolylcarboxypeptidase, DPP4N_Peptidase_S9
References (3)
| Title : Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein - Lee_2006_Blood_107_1397 |
| Author(s) : Lee KN , Jackson KW , Christiansen VJ , Lee CS , Chun JG , McKee PA |
| Ref : Blood , 107 :1397 , 2006 |
| Abstract : Lee_2006_Blood_107_1397 |
| ESTHER : Lee_2006_Blood_107_1397 |
| PubMedSearch : Lee_2006_Blood_107_1397 |
| PubMedID: 16223769 |
| Gene_locus related to this paper: human-FAP |
| Title : N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding - Aertgeerts_2004_Protein.Sci_13_145 |
| Author(s) : Aertgeerts K , Ye S , Shi L , Prasad SG , Witmer D , Chi E , Sang BC , Wijnands RA , Webb DR , Swanson RV |
| Ref : Protein Science , 13 :145 , 2004 |
| Abstract : Aertgeerts_2004_Protein.Sci_13_145 |
| ESTHER : Aertgeerts_2004_Protein.Sci_13_145 |
| PubMedSearch : Aertgeerts_2004_Protein.Sci_13_145 |
| PubMedID: 14691230 |
| Title : Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase - Underwood_1999_J.Biol.Chem_274_34053 |
| Author(s) : Underwood R , Chiravuri M , Lee H , Schmitz T , Kabcenell AK , Yardley K , Huber BT |
| Ref : Journal of Biological Chemistry , 274 :34053 , 1999 |
| Abstract : Underwood_1999_J.Biol.Chem_274_34053 |
| ESTHER : Underwood_1999_J.Biol.Chem_274_34053 |
| PubMedSearch : Underwood_1999_J.Biol.Chem_274_34053 |
| PubMedID: 10567372 |
| Gene_locus related to this paper: human-DPP7 |