Amplex-red
General
Type : Phenoxazin || Derivative of Resorufin || Not A\/B H target || Fluorescent Probe
Chemical_Nomenclature : 1-(3,7-dihydroxyphenoxazin-10-yl)ethanone
Canonical SMILES : CC(=O)N1C2=C(C=C(C=C2)O)OC3=C1C=CC(=C3)O
InChI : InChI=1S\/C14H11NO4\/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15\/h2-7,17-18H,1H3
InChIKey : PKYCWFICOKSIHZ-UHFFFAOYSA-N
Other name(s) : 10-Acetyl-3,7-dihydroxyphenoxazine, 1-(3,7-Dihydroxy-10H-phenoxazin-10-yl)ethanone, ADHP, Amplex red
Target
Families : Carb_B_Chordata
References (4)
| Title : Discovery of dual cation-pi inhibitors of acetylcholinesterase: design, synthesis and biological evaluation - Damuka_2020_Pharmacol.Rep__ |
| Author(s) : Damuka N , Kammari K , Potshangbam AM , Rathore RS , Kondapi AK , Vindal V |
| Ref : Pharmacol Rep , : , 2020 |
| Abstract : Damuka_2020_Pharmacol.Rep__ |
| ESTHER : Damuka_2020_Pharmacol.Rep__ |
| PubMedSearch : Damuka_2020_Pharmacol.Rep__ |
| PubMedID: 32200493 |
| Title : Identification of acetylcholinesterase inhibitors using homogenous cell-based assays in quantitative high-throughput screening platforms - Li_2017_Biotechnol.J_12_ |
| Author(s) : Li S , Huang R , Solomon S , Liu Y , Zhao B , Santillo MF , Xia M |
| Ref : Biotechnol J , 12 : , 2017 |
| Abstract : Li_2017_Biotechnol.J_12_ |
| ESTHER : Li_2017_Biotechnol.J_12_ |
| PubMedSearch : Li_2017_Biotechnol.J_12_ |
| PubMedID: 28294544 |
| Title : Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays - Miwa_2016_Free.Radic.Biol.Med_90_173 |
| Author(s) : Miwa S , Treumann A , Bell A , Vistoli G , Nelson G , Hay S , von Zglinicki T |
| Ref : Free Radic Biol Med , 90 :173 , 2016 |
| Abstract : Miwa_2016_Free.Radic.Biol.Med_90_173 |
| ESTHER : Miwa_2016_Free.Radic.Biol.Med_90_173 |
| PubMedSearch : Miwa_2016_Free.Radic.Biol.Med_90_173 |
| PubMedID: 26577176 |
| Title : A fluorescence assay for measuring acetylcholinesterase activity in rat blood and a human neuroblastoma cell line (SH-SY5Y) - Santillo_2015_J.Pharmacol.Toxicol.Methods_76_15 |
| Author(s) : Santillo MF , Liu Y |
| Ref : Journal of Pharmacological & Toxicological Methodsods , 76 :15 , 2015 |
| Abstract : Santillo_2015_J.Pharmacol.Toxicol.Methods_76_15 |
| ESTHER : Santillo_2015_J.Pharmacol.Toxicol.Methods_76_15 |
| PubMedSearch : Santillo_2015_J.Pharmacol.Toxicol.Methods_76_15 |
| PubMedID: 26165232 |