Chloramphenicol
General
Type : Antibiotic || pNP
Chemical_Nomenclature : 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
Canonical SMILES : C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
InChI : InChI=1S\/C11H12Cl2N2O5\/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20\/h1-4,8-10,16-17H,5H2,(H,14,18)\/t8-,9-\/m1\/s1
InChIKey : WIIZWVCIJKGZOK-RKDXNWHRSA-N
Other name(s) : Chloromycetin, Chlornitromycin, Levomycetin, Chlorocid
Target
Families : Hormone-sensitive_lipase_like
References (5)
| Title : Crystal structure of chloramphenicol-metabolizing enzyme EstDL136 from a metagenome - Kim_2019_PLoS.One_14_e0210298 |
| Author(s) : Kim SH , Kang PA , Han K , Lee SW , Rhee S |
| Ref : PLoS ONE , 14 :e0210298 , 2019 |
| Abstract : Kim_2019_PLoS.One_14_e0210298 |
| ESTHER : Kim_2019_PLoS.One_14_e0210298 |
| PubMedSearch : Kim_2019_PLoS.One_14_e0210298 |
| PubMedID: 30645605 |
| Gene_locus related to this paper: 9bact-g3cr02 |
| Title : Inactivation of chloramphenicol and florfenicol by a novel chloramphenicol hydrolase - Tao_2012_Appl.Environ.Microbiol_78_6295 |
| Author(s) : Tao W , Lee MH , Wu J , Kim NH , Kim JC , Chung E , Hwang EC , Lee SW |
| Ref : Applied Environmental Microbiology , 78 :6295 , 2012 |
| Abstract : Tao_2012_Appl.Environ.Microbiol_78_6295 |
| ESTHER : Tao_2012_Appl.Environ.Microbiol_78_6295 |
| PubMedSearch : Tao_2012_Appl.Environ.Microbiol_78_6295 |
| PubMedID: 22752166 |
| Gene_locus related to this paper: 9bact-g3cr00 , 9bact-g3cr02 |
| Title : Characterization of two metagenome-derived esterases that reactivate chloramphenicol by counteracting chloramphenicol acetyltransferase - Tao_2011_J.Microbiol.Biotechnol_21_1203 |
| Author(s) : Tao W , Lee MH , Yoon MY , Kim JC , Malhotra S , Wu J , Hwang EC , Lee SW |
| Ref : J Microbiol Biotechnol , 21 :1203 , 2011 |
| Abstract : Tao_2011_J.Microbiol.Biotechnol_21_1203 |
| ESTHER : Tao_2011_J.Microbiol.Biotechnol_21_1203 |
| PubMedSearch : Tao_2011_J.Microbiol.Biotechnol_21_1203 |
| PubMedID: 22210605 |
| Gene_locus related to this paper: 9bact-g3cr00 , 9bact-g3cr02 |
| Title : Enzymatic inactivation and reactivation of chloramphenicol by Mycobacterium tuberculosis and Mycobacterium bovis - Sohaskey_2004_FEMS.Microbiol.Lett_240_187 |
| Author(s) : Sohaskey CD |
| Ref : FEMS Microbiology Letters , 240 :187 , 2004 |
| Abstract : Sohaskey_2004_FEMS.Microbiol.Lett_240_187 |
| ESTHER : Sohaskey_2004_FEMS.Microbiol.Lett_240_187 |
| PubMedSearch : Sohaskey_2004_FEMS.Microbiol.Lett_240_187 |
| PubMedID: 15522506 |
| Title : Identification of the chloramphenicol-hydrolyzing enzyme of guinea pig liver as one of the nonspecific carboxylesterases - Kuhn_1982_Biochem.Pharmacol_31_781 |
| Author(s) : Kuhn D , Heymann E |
| Ref : Biochemical Pharmacology , 31 :781 , 1982 |
| Abstract : Kuhn_1982_Biochem.Pharmacol_31_781 |
| ESTHER : Kuhn_1982_Biochem.Pharmacol_31_781 |
| PubMedSearch : Kuhn_1982_Biochem.Pharmacol_31_781 |
| PubMedID: 7082346 |