Ciclesonide

General

Type : Not A\/B H target || Pro-Drug || Butyrate || Drug

Chemical_Nomenclature : (R)-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate

Canonical SMILES :

InChI :

InChIKey :

Other name(s) : Omnaris,     Alvesco,     Zetonna,     DB01410


MW : 540.69

Formula : C32H44O7

CAS_number : 126544-47-6

PubChem :

UniChem :

Iuphar :

Target

Families : Carb_B_Chordata, BCHE

References (3)

Title : Metabolism of ciclesonide in the upper and lower airways: review of available data - Nave_2008_J.Asthma.Allergy_1_11
Author(s) : Nave R , McCracken N
Ref : J Asthma Allergy , 1 :11 , 2008
Abstract : Nave_2008_J.Asthma.Allergy_1_11
ESTHER : Nave_2008_J.Asthma.Allergy_1_11
PubMedSearch : Nave_2008_J.Asthma.Allergy_1_11
PubMedID: 21436981

Title : The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue - Mutch_2007_Biochem.Pharmacol_73_1657
Author(s) : Mutch E , Nave R , McCracken N , Zech K , Williams FM
Ref : Biochemical Pharmacology , 73 :1657 , 2007
Abstract : Mutch_2007_Biochem.Pharmacol_73_1657
ESTHER : Mutch_2007_Biochem.Pharmacol_73_1657
PubMedSearch : Mutch_2007_Biochem.Pharmacol_73_1657
PubMedID: 17331475

Title : In vitro metabolism of ciclesonide in human nasal epithelial cells - Sato_2007_Biopharm.Drug.Dispos_28_43
Author(s) : Sato H , Nave R , Nonaka T , Mochizuki T , Takahama S , Kondo S
Ref : Biopharmaceutics & Drug Disposition , 28 :43 , 2007
Abstract : Sato_2007_Biopharm.Drug.Dispos_28_43
ESTHER : Sato_2007_Biopharm.Drug.Dispos_28_43
PubMedSearch : Sato_2007_Biopharm.Drug.Dispos_28_43
PubMedID: 17117454