Procaine

General

Type : Local anesthetic || Drug || Not A\/B H target

Chemical_Nomenclature : 4-Aminobenzoic acid 2-(diethylamino) ethyl ester hydrochloride

Canonical SMILES : CCN(CC)CCOC(=O)C1=CC=C(C=C1)N

InChI : InChI=1S\/C13H20N2O2\/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11\/h5-8H,3-4,9-10,14H2,1-2H3

InChIKey : MFDFERRIHVXMIY-UHFFFAOYSA-N

Other name(s) : Duracaine,     Novocain,     Novocaine,     Spinocaine,     Vitamin H3,     Nissocaine,     Procain,     Procaine, base,     Gerovital


MW : 236.31

Formula : C13H20N2O2.HCl

CAS_number : 59-46-1

PubChem :

UniChem :

Iuphar :

Target

Families : BCHE, Carb_B_Chordata

References (5)

Title : Comparison of substrate specificity among human arylacetamide deacetylase and carboxylesterases - Fukami_2015_Eur.J.Pharm.Sci_78_47
Author(s) : Fukami T , Kariya M , Kurokawa T , Iida A , Nakajima M
Ref : Eur J Pharm Sci , 78 :47 , 2015
Abstract : Fukami_2015_Eur.J.Pharm.Sci_78_47
ESTHER : Fukami_2015_Eur.J.Pharm.Sci_78_47
PubMedSearch : Fukami_2015_Eur.J.Pharm.Sci_78_47
PubMedID: 26164127
Gene_locus related to this paper: human-AADAC , human-CES1 , human-CES2

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35
Author(s) : Lockridge O
Ref : Pharmacol Ther , 47 :35 , 1990
Abstract : Lockridge_1990_Pharmacol.Ther_47_35
ESTHER : Lockridge_1990_Pharmacol.Ther_47_35
PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35
PubMedID: 2195556
Gene_locus related to this paper: human-BCHE

Title : Prediction of drug sensitivity in individuals with atypical serum cholinesterase based on in vitro biochemical studies - Valentino_1981_Biochem.Pharmacol_30_1643
Author(s) : Valentino RJ , Lockridge O , Eckerson HW , La Du BN
Ref : Biochemical Pharmacology , 30 :1643 , 1981
Abstract : Valentino_1981_Biochem.Pharmacol_30_1643
ESTHER : Valentino_1981_Biochem.Pharmacol_30_1643
PubMedSearch : Valentino_1981_Biochem.Pharmacol_30_1643
PubMedID: 7271851

Title : Differential inhibition of plasma cholinesterase variants using the dibutyrate analogue of pancuronium bromide - Whittaker_1981_Hum.Hered_31_242
Author(s) : Whittaker M , Britten JJ
Ref : Hum Hered , 31 :242 , 1981
Abstract : Whittaker_1981_Hum.Hered_31_242
ESTHER : Whittaker_1981_Hum.Hered_31_242
PubMedSearch : Whittaker_1981_Hum.Hered_31_242
PubMedID: 7287015

Title : The activity of various esterase inhibitors towards atypical human serum cholinesterase -
Author(s) : Kalow W , Davies R0
Ref : Biochemical Pharmacology , 1 :183 , 1958
PubMedID: