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Type_inhibitor Report for: Derivative of physostigmine-eserine

Physostigmine-eserine carbamate alkaloid purified from the calabar bean: Physostigma venenosum. Physostigmine is a cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier.

InhibitorMain targeted enzyme familiesTypeStructure
(-)-phenethylcymserineACHE | BCHE | Carb_B_Chordata Carbamate | Derivative of physostigmine-eserine
Bis-NoreserolineACHE Derivative of physostigmine-eserine | Indole | Leaving group
BisnorcymserineACHE | BCHE Carbamate | Derivative of physostigmine-eserine | Indole
CID656508 Carbamate | Derivative of physostigmine-eserine | Indole
CymserineBCHE Carbamate | Derivative of physostigmine-eserine | Indole
Debromoflustramine-BBCHE Derivative of physostigmine-eserine | Indole | Natural | Pyrrolidine
Dihydrobenzodioxepine-cymeserineBCHE Carbamate | Derivative of physostigmine-eserine
EserolineACHE Derivative of physostigmine-eserine | Indole
GanstigmineACHE Carbamate | Derivative of physostigmine-eserine | Indole
GeneserineACHE | BCHE Carbamate | Derivative of physostigmine-eserine | Indole | Natural
Geneseroline Derivative of physostigmine-eserine | Indole | Natural
HeptylphysostigmineACHE Carbamate | Derivative of physostigmine-eserine | Indole
MF217ACHE Carbamate | Derivative of physostigmine-eserine | Indole | Morpholine
MF268ACHE Carbamate | Derivative of physostigmine-eserine | Indole | Morpholine
N1-PhenethylnorcymserineBCHE Carbamate | Derivative of physostigmine-eserine | Indole
PhenserineACHE Carbamate | Derivative of physostigmine-eserine | Drug | Indole
Physostigmine-methiodideACHE Carbamate | Derivative of physostigmine-eserine | Indole | Natural_modified
Physostigmine~EserineACHE | Arylacetamide_deacetylase | BCHE Carbamate | Derivative of physostigmine-eserine | Drug | Indole | Natural
PhysovenineACHE Carbamate | Derivative of physostigmine-eserine | Indole | Natural
PosiphenACHE Carbamate | Derivative of physostigmine-eserine | Drug | Indole
QuilostigmineACHE Carbamate | Derivative of physostigmine-eserine | Indole | Isoquinoline
Tetrahydrofurobenzofuran-cymserine Carbamate | Derivative of physostigmine-eserine
TolserineACHE | BCHE Carbamate | Derivative of physostigmine-eserine | Indole | NTE inhibitor | Not A/B H target

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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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