for example to search all human alpha/beta hydrolase found in human genome enter this search in the window below:
select a, fam, nam, c from a in class Gene_locus,
spec in a->Species where spec.name like "Homo sapiens",
fam in a->Family,
nam in a->Name,
c in count(select a->Structure)
sort by: fam, :nam

for more examples from esther go to AQL esther
for examples from esther on insecticide resistance go to AQL esther resistance
for more examples from wormbase go to AQL wormbase
AQL for the supplementary material of the Pucon Poster Pucon Poster
 
207 rows returned
Paper Text Year
Kranawetvogl_2024_Arch.Toxicol__ The phosphylated butyrylcholinesterase-derived tetrapeptide GlyGluSerAla proves exposure to organophosphorus agents with enantioselectivity 2024
Fernandez-Lopez_2023_Chem.Commun.(Camb)__ Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor 2023
Priya_2023_Chem.Commun.(Camb)_59_12274 Hydroxynitrile lyase engineering for promiscuous asymmetric Henry reaction with enhanced conversion, enantioselectivity and catalytic efficiency 2023
Vaaland_2023_J.Enzyme.Inhib.Med.Chem_38_349 Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers 2023
Du_2023_Chem.Sci_14_506 In vivo visualization of enantioselective targeting of amyloid and improvement of cognitive function by clickable chiral metallohelices 2023
Snajdarova_2023_Acta.Crystallogr.D.Struct.Biol__ Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum 2023
Dou_2022_Catal.Sci.Technol_12_7448 Structural and mechanistic insights into enantioselectivity toward near-symmetric esters of a novel carboxylesterase RoCE 2022
Vishnu_2022_Bioorg.Chem_120_105594 Enzyme engineering improves catalytic efficiency and enantioselectivity of hydroxynitrile lyase for promiscuous retro-nitroaldolase activity 2022
Braa_2022_Org.Biomol.Chem__ Access to valuable building blocks by the regio- and enantioselective ring opening of itaconic anhydride by lipase catalysis 2022
Arnipalli_2022_Chirality__ New enantioselective liquid chromatography method development and validation of dipeptidyl peptidase IV inhibitors using a macrocyclic glycopeptide (vancomycin) chiral stationary phase under polar ionic mode condition 2022
Martelli_2022_Bioorg.Chem_120_105580 Chemoenzymatic enantioselective route to get (+) and (-) 4-acetoxy-azetidin-2-one by lipase-catalysed kinetic resolution and their applications 2022
Simonsen_2022_Environ.Toxicol.Pharmacol_96_104008 The dichloroacetamide safener benoxacor is enantioselectively metabolized by monkey liver microsomes and cytosol 2022
Wen_2021_Enzyme.Microb.Technol_146_109778 Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide 2021
Ran_2021_Ecotoxicol.Environ.Saf_226_112809 The enantioselective toxicity and oxidative stress of dinotefuran on zebrafish (Danio rerio) 2021
Park_2021_Appl.Biol.Chem_64_81 Biochemical characterization of a family IV esterase with R-form enantioselectivity from a compost metagenomic library 2021
Borowiecki_2021_Mol.Catal_504_111451 Chemoenzymatic enantioselective and stereo-convergent syntheses of lisofylline enantiomers via lipase-catalyzed kinetic resolution and optical inversion approach 2021
Hu_2020_Ecotoxicol.Environ.Saf_205_111141 A novel esterase LanE from Edaphocola flava HME-24 and the enantioselective degradation mechanism of herbicide lactofen 2020
Li_2020_Int.J.Biol.Macromol_156_225 Greatly enhancing the enantioselectivity of PvEH2, a Phaseolus vulgaris epoxide hydrolase, towards racemic 1,2-epoxyhexane via replacing its partial cap-loop 2020
Zhang_2020_Sci.Rep_10_1680 Significant improvement in catalytic activity and enantioselectivity of a Phaseolus vulgaris epoxide hydrolase, PvEH3, towards ortho-cresyl glycidyl ether based on the semi-rational design 2020
Su_2020_Enzyme.Microb.Technol_133_109467 Cutinases as stereoselective catalysts: Specific activity and enantioselectivity of cutinases and lipases for menthol and its analogs 2020
Hu_2020_Int.J.Biol.Macromol_147_1213 Near-perfect kinetic resolution of racemic p-chlorostyrene oxide by SlEH1, a novel epoxide hydrolase from Solanum lycopersicum with extremely high enantioselectivity 2020
Xue_2020_Appl.Microbiol.Biotechnol_104_2067 Significant improvement of the enantioselectivity of a halohydrin dehalogenase for asymmetric epoxide ring opening reactions by protein engineering 2020
Simonsen_2020_Chem.Biol.Interact__109247 Benoxacor is enantioselectively metabolized by rat liver subcellular fractions 2020
de Almeida_2020_Mol.Catal_488_110926 Lipase-catalysed enantioselective kinetic resolution of rac-lipidic alkynylcarbinols and a C5 synthon thereof via a hydrolysis approach 2020
Li_2019_Mol.Catal_476_110517 Improving the activity and enantioselectivity of PvEH1, a Phaseolus vulgaris epoxide hydrolase, for o-methylphenyl glycidyl ether by multiple site-directed mutagenesis on the basis of rational design 2019
Han_2019_Bioprocess.Biosyst.Eng_42_1739 Rational enhancement of enzyme-catalyzed enantioselective reaction by construction of recombinant enzymes based on additive strategy 2019
Zhang_2019_Int.J.Biol.Macromol_140_358 Purification and characterization of a thermoalkaliphilic esterase from Bacillus cereus WZZ006 for enantioselective resolution of indoxacarb intermediate 2019
Zhang_2019_Biotechnol.Lett_41_1223 Purification, identification and characterization of an esterase with high enantioselectivity to (S)-ethyl indoline-2-carboxylate 2019
Yoo_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_1438 A novel enantioselective SGNH family esterase (NmSGNH1) from Neisseria meningitides: Characterization, mutational analysis, and ester synthesis 2019
Chen_2018_J.Mol.Graph.Model_85_182 Structural investigation of the enantioselectivity and thermostability mechanisms of esterase RhEst1 2018
Zou_2018_Appl.Microbiol.Biotechnol_102_733 Enhanced catalytic efficiency and enantioselectivity of epoxide hydrolase from Agrobacterium radiobacter AD1 by iterative saturation mutagenesis for (R)-epichlorohydrin synthesis 2018
Zhang_2018_J.Hazard.Mater_341_336 Detoxification of diphenyl ether herbicide lactofen by Bacillus sp. Za and enantioselective characteristics of an esterase gene lacE 2018
Ma_2018_Nat.Commun_9_1030 Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform 2018
Saraswat_2018_3.Biotech_8_491 Production and purification of an alkaline lipase from Bacillus sp. for enantioselective resolution of (+/-)-Ketoprofen butyl ester 2018
de Morais Junior_2018_Mol.Catal_458_89 Influence of different immobilization techniques to improve the enantioselectivity of lipase from Geotrichum candidum applied on the resolution of mandelic acid 2018
Cadet_2018_Sci.Rep_8_16757 A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes 2018
Zhang_2017_Microb.Cell.Fact_16_112 Biochemical characterization of an enantioselective esterase from Brevundimonas sp. LY-2 2017
Jones_2017_ACS.Catal_7_4221 Identical active sites in hydroxynitrile lyases show opposite enantioselectivity and reveal possible ancestral mechanism 2017
Zaugg_2017_J.Comput.Aided.Mol.Des_31_1085 Learning epistatic interactions from sequence-activity data to predict enantioselectivity 2017
Millar_2017_Biotechnol.Appl.Biochem_64_803 Esterase EstK from Pseudomonas putida mt-2: An enantioselective acetylesterase with activity for deacetylation of xylan and poly(vinylacetate) 2017
Kim_2017_Appl.Microbiol.Biotechnol_101_2333 Crystal structure and characterization of esterase Est25 mutants reveal improved enantioselectivity toward (S)-ketoprofen ethyl ester 2017
Wahab_2016_Enzyme.Microb.Technol_93-94_174 Facile modulation of enantioselectivity of thermophilic Geobacillus zalihae lipase by regulating hydrophobicity of its Q114 oxyanion 2016
Manickam_2016_Eur.J.Med.Chem_117_113 Discovery of enantioselectivity of urea inhibitors of soluble epoxide hydrolase 2016
Archelas_2016_Arch.Biochem.Biophys_591_66 Epoxide hydrolase-catalyzed enantioselective conversion of trans-stilbene oxide: Insights into the reaction mechanism from steady-state and pre-steady-state enzyme kinetics 2016
Singh_2016_Enzyme.Microb.Technol_83_29 Novel S-enantioselective lipase TALipB from Trichosporon asahii MSR54: Heterologous expression, characterization, conformational stability and homology modeling 2016
Xue_2015_RSC.Adv_5_31525 Engineering the epoxide hydrolase from Agromyces mediolanus for enhanced enantioselectivity and activity in the kinetic resolution of racemic epichlorohydrin 2015
Shimotori_2015_J.Oleo.Sci_64_561 Combination of Novozym 435-catalyzed enantioselective hydrolysis and amidation for the preparation of optically active delta-hexadecalactone 2015
Min_2015_Chembiochem_16_77 Hydrogen-bonding-driven enantioselective resolution against the Kazlauskas rule to afford gamma-amino alcohols by Candida rugosa lipase 2015
Yao_2015_J.Sep.Sci_38_1663 Simultaneous enantioselective determination of isocarbophos and its main metabolite isocarbophos oxon in rice, soil, and water by chiral liquid chromatography and tandem mass spectrometry 2015
Hu_2015_J.Biotechnol_194_12 Immobilization of Aspergillus terreus lipase in self-assembled hollow nanospheres for enantioselective hydrolysis of ketoprofen vinyl ester 2015
Kim_2015_Appl.Microbiol.Biotechnol_99_6293 Improved enantioselectivity of thermostable esterase from Archaeoglobus fulgidus toward (S)-ketoprofen ethyl ester by directed evolution and characterization of mutant esterases 2015
Xue_2014_Process.Biochem_49_409 A novel enantioselective epoxide hydrolase from Agromyces mediolanus ZJB120203: Cloning, characterization and application 2014
Guan_2014_Appl.Microbiol.Biotechnol_98_8573 Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism 2014
Rozeboom_2014_Biochim.Biophys.Acta_1844_567 Crystal structures of two Bacillus carboxylesterases with different enantioselectivities 2014
Tobis_2014_Biotechnol.Lett_36_1661 Impact of the configuration of a chiral, activating carrier on the enantioselectivity of entrapped lipase from Candida rugosa in cyclohexane 2014
Guo_2014_Biotechnol.Bioeng_111_1729 Controlling enantioselectivity of esterase in asymmetric hydrolysis of aryl prochiral diesters by introducing aromatic interactions 2014
Tang_2014_Biotechnol.Lett_36_633 Residue Val237 is critical for the enantioselectivity of Penicillium expansum lipase 2014
Lopez_2014_Appl.Microbiol.Biotechnol_98_8603 A novel thermoalkalostable esterase from Acidicaldus sp. strain USBA-GBX-499 with enantioselectivity isolated from an acidic hot springs of Colombian Andes 2014
Zhang_2014_Biochim.Biophys.Acta_1844_1183 Structure, mechanism, and enantioselectivity shifting of lipase LipK107 with a simple way 2014
Sikora_2014_Chirality_26_663 Kinetic resolution of profens by enantioselective esterification catalyzed by Candida antarctica and Candida rugosa lipases 2014
Wei_2013_J.Mol.Catal.B.Enzym_97_270 Cloning, expression and characterization of a new enantioselective esterase from a marine bacterium Pelagibacterium halotolerans B2T 2013
Liu_2013_Appl.Microbiol.Biotechnol_97_7659 Enzymatic production of Cilastatin intermediate via highly enantioselective hydrolysis of methyl (+/-)-2,2-dimethylcyclopropane carboxylate using newly isolated Rhodococcus sp. ECU1013 2013
Li_2013_BMC.Biotechnol_13_92 Improving activity and enantioselectivity of lipase via immobilization on macroporous resin for resolution of racemic 1- phenylethanol in non-aqueous medium 2013
Jeon_2013_J.Biotechnol_168_201 Lipase-catalyzed enantioselective synthesis of (R,R)-lactide from alkyl lactate to produce PDLA (poly D-lactic acid) and stereocomplex PLA (poly lactic acid) 2013
Tang_2013_World.J.Microbiol.Biotechnol_29_145 Substitution of Val72 residue alters the enantioselectivity and activity of Penicillium expansum lipase 2013
Ma_2013_Appl.Microbiol.Biotechnol_97_4897 Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution 2013
Guo_2013_Appl.Microbiol.Biotechnol_97_3355 Compensation of the enantioselectivity-activity trade-off in the directed evolution of an esterase from Rhodobacter sphaeroides by site-directed saturation mutagenesis 2013
Nobili_2013_FEBS.J_280_3084 Use of 'small but smart' libraries to enhance the enantioselectivity of an esterase from Bacillus stearothermophilus towards tetrahydrofuran-3-yl acetate 2013
Beloti_2013_Protein.Expr.Purif_91_175 A novel and enantioselective epoxide hydrolase from Aspergillus brasiliensis CCT 1435: Purification and characterization 2013
Lee_2013_Biotechnol.Lett_35_1677 Expression of a lipase on the cell-surface of Escherichia coli using the OmpW anchoring motif and its application to enantioselective reactions 2013
Andexer_2012_Chembiochem_13_1932 Hydroxynitrile lyases with alpha/beta-hydrolase fold: two enzymes with almost identical 3D structures but opposite enantioselectivities and different reaction mechanisms 2012
Godinho_2012_J.Biotechnol_158_36 Enhancement of the enantioselectivity of carboxylesterase A by structure-based mutagenesis 2012
Ema_2012_Org.Biomol.Chem_10_6299 Redesign of enzyme for improving catalytic activity and enantioselectivity toward poor substrates: manipulation of the transition state 2012
Frushicheva_2012_Chembiochem_13_215 Towards quantitative computer-aided studies of enzymatic enantioselectivity: the case of Candida antarctica lipase A 2012
Sandstrom_2012_Proc.Natl.Acad.Sci.U.S.A_109_78 Combinatorial reshaping of the Candida antarctica lipase A substrate pocket for enantioselectivity using an extremely condensed library 2012
Godinho_2012_Adv.Synth.Catal_354_3009 An esterase with superior activity and enantioselectivity towards 1,2-O-isopropylideneglycerol esters obtained by protein design 2012
Torres_2012_Org.Biomol.Chem_10_3388 Promiscuous enantioselective (-)-gamma-lactamase activity in the Pseudomonas fluorescens esterase I 2012
Li_2012_Biotechnol.Lett_34_153 Resolution of 2-nitroalcohols by Burkholderia cepacia lipase-catalyzed enantioselective acylation 2012
Yilmaz_2011_Bioresour.Technol_102_499 Immobilization of Candida rugosa lipase on glass beads for enantioselective hydrolysis of racemic naproxen methyl ester 2011
Kawai_2011_Polym.Degrad.Stab_96_1342 Different enantioselectivity of two types of poly(lactic acid) depolymerases toward poly(l-lactic acid) and poly(d-lactic acid) 2011
Godinho_2011_Appl.Environ.Microbiol_77_6094 Discovery of an Escherichia coli esterase with high activity and enantioselectivity toward 1,2-O-isopropylideneglycerol esters 2011
Prasad_2011_Chemphyschem_12_1550 Revisiting the lipase from Pseudomonas aeruginosa: directed evolution of substrate acceptance and enantioselectivity using iterative saturation mutagenesis 2011
Palm_2011_Appl.Microbiol.Biotechnol_91_1061 The crystal structure of an esterase from the hyperthermophilic microorganism Pyrobaculum calidifontis VA1 explains its enantioselectivity 2011
Reetz_2011_Chembiochem_12_1529 Manipulating the expression rate and enantioselectivity of an epoxide hydrolase by using directed evolution 2011
Fernandez-Alvaro_2011_Angew.Chem.Int.Ed.Engl_50_8584 A combination of in vivo selection and cell sorting for the identification of enantioselective biocatalysts 2011
Kim_2011_Angew.Chem.Int.Ed.Engl_50_10944 Ionic-surfactant-coated Burkholderia cepacia lipase as a highly active and enantioselective catalyst for the dynamic kinetic resolution of secondary alcohols 2011
Ju_2010_Appl.Microbiol.Biotechnol_86_83 Bioproduction of chiral mandelate by enantioselective deacylation of alpha-acetoxyphenylacetic acid using whole cells of newly isolated Pseudomonas sp. ECU1011 2010
Grosse_2010_Microb.Biotechnol_3_65 Nature versus nurture in two highly enantioselective esterases from Bacillus cereus and Thermoanaerobacter tengcongensis 2010
Vallin_2010_Chembiochem_11_411 Mutant lipase-catalyzed kinetic resolution of bulky phenyl alkyl sec-alcohols: a thermodynamic analysis of enantioselectivity 2010
Karadeniz_2010_Artif.Cells.Blood.Substit.Immobil.Biotechnol_38_288 Kinetic resolution of racemic 1-phenyl 1-propanol by lipase catalyzed enantioselective esterification reaction 2010
Engstrom_2010_J.Am.Chem.Soc_132_7038 Directed evolution of an enantioselective lipase with broad substrate scope for hydrolysis of alpha-substituted esters 2010
Cambon_2010_Biotechnol.Bioeng_106_852 Rationally engineered double substituted variants of Yarrowia lipolytica lipase with enhanced activity coupled with highly inverted enantioselectivity towards 2-bromo phenyl acetic acid esters 2010
Ghanem_2010_Chirality_22_597 Direct enantioselective HPLC monitoring of lipase-catalyzed kinetic resolution of flurbiprofen 2010
Ohara_2010_Biomacromolecules_11_2008 Lipase-catalyzed oligomerization and hydrolysis of alkyl lactates: direct evidence in the catalysis mechanism that enantioselection is governed by a deacylation step 2010
Schuchert-Shi_2010_Chirality_22_331 Following the lipase catalyzed enantioselective hydrolysis of amino acid esters with capillary electrophoresis using contactless conductivity detection 2010
Ghanem_2010_J.Chromatogr.A_1217_1063 Lipase-mediated enantioselective kinetic resolution of racemic acidic drugs in non-standard organic solvents: Direct chiral liquid chromatography monitoring and accurate determination of the enantiomeric excesses 2010
Xu_2010_Biochim.Biophys.Acta_1804_2183 Template-based modeling of a psychrophilic lipase: conformational changes, novel structural features and its application in predicting the enantioselectivity of lipase catalyzed transesterification of secondary alcohols 2010
Arunkumar_2010_Beilstein.J.Org.Chem_6_1174 Achiral bis-imine in combination with CoCl(2): A remarkable effect on enantioselectivity of lipase-mediated acetylation of racemic secondary alcohol 2010
Otten_2010_Trends.Biotechnol_28_46 Enzyme engineering for enantioselectivity: from trial-and-error to rational design? 2010
van Loo_2009_Enz.Microb.Technol_44_145 Improved enantioselective conversion of styrene epoxides and meso-epoxides through epoxide hydrolases with a mutated nucleophile-flanking residue 2009
Reetz_2009_J.Am.Chem.Soc_131_7334 Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage 2009
Lafaquiere_2009_Chembiochem_10_2760 Control of lipase enantioselectivity by engineering the substrate binding site and access channel 2009
Schliessmann_2009_Chembiochem_10_2920 Increased enantioselectivity by engineering bottleneck mutants in an esterase from Pseudomonas fluorescens 2009
Bordes_2009_Chembiochem_10_1705 Improvement of Yarrowia lipolytica lipase enantioselectivity by using mutagenesis targeted to the substrate binding site 2009
Juhl_2009_BMC.Struct.Biol_9_39 Modelling substrate specificity and enantioselectivity for lipases and esterases by substrate-imprinted docking 2009
Melzer_2009_J.Am.Chem.Soc_131_17226 Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design 2009
Takac_2009_Prep.Biochem.Biotechnol_39_124 Effects of alcohol and buffer treatments on the activity and enantioselectivity of Candida rugosa lipase 2009
Contesini_2009_J.Microbiol_47_563 Response surface analysis for the production of an enantioselective lipase from Aspergillus niger by solid-state fermentation 2009
Boersma_2008_Chem.Biol_15_782 Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity 2008
Bartsch_2008_Angew.Chem.Int.Ed.Engl_47_1508 Complete inversion of enantioselectivity towards acetylated tertiary alcohols by a double mutant of a Bacillus subtilis esterase 2008
Reetz_2008_Chem.Commun.(Camb)__5502 A genetic selection system for evolving enantioselectivity of enzymes 2008
Hausmann_2008_FEMS.Microbiol.Lett_282_65 Mutations towards enantioselectivity adversely affect secretion of Pseudomonas aeruginosa lipase 2008
Monti_2008_J.Biotechnol_133_65 Purification and characterization of the enantioselective esterase from Kluyveromyces marxianus CBS 1553 2008
Wei_2008_Appl.Biochem.Biotechnol_149_79 Screening and immobilization Burkholderia sp. GXU56 lipase for enantioselective resolution of (R,S)-methyl mandelate 2008
Koch_2008_Biotechnol.Bioeng_99_1028 Enzymatic enantioselective C-C-bond formation in microreactors 2008
Lee_2008_J.Microbiol.Biotechnol_18_465 Development of magnetically separable immobilized lipase by using cellulose derivatives and their application in enantioselective esterification of ibuprofen 2008
Hwang_2008_Mar.Biotechnol.(NY)_10_366 Screening enantioselective epoxide hydrolase activities from marine microorganisms: detection of activities in Erythrobacter spp 2008
Chen_2008_Langmuir_24_8877 Immobilization of lipases on hydrophobilized zirconia nanoparticles: highly enantioselective and reusable biocatalysts 2008
Deng_2008_J.Chromatogr.A_1198-1199_67 Direct separation of monoacylglycerol isomers by enantioselective high-performance liquid chromatography 2008
Guieysse_2008_Chembiochem_9_1308 A structure-controlled investigation of lipase enantioselectivity by a path-planning approach 2008
Kim_2008_Org.Lett_10_1295 Highly enantioselective dynamic kinetic resolution of 1,2-diarylethanols by a lipase-ruthenium couple 2008
Miyazawa_2008_Biotechnol.Lett_30_1783 Resolution of secondary alcohols via Carica papaya lipase-catalyzed enantioselective acylation 2008
Lee_2007_Biotechnol.Lett_29_237 Cloning, expression and enantioselective hydrolytic catalysis of a microsomal epoxide hydrolase from a marine fish, Mugil cephalus 2007
Wu_2007_Appl.Microbiol.Biotechnol_76_1281 A novel enantioselective epoxide hydrolase for (R)-phenyl glycidyl ether to generate (R)-3-phenoxy-1,2-propanediol 2007
Kotik_2007_J.Biotechnol_132_8 Cloning of an epoxide hydrolase-encoding gene from Aspergillus niger M200, overexpression in E. coli, and modification of activity and enantioselectivity of the enzyme by protein engineering 2007
Heinze_2007_Protein.Eng.Des.Sel_20_125 Highly enantioselective kinetic resolution of two tertiary alcohols using mutants of an esterase from Bacillus subtilis 2007
Koga_2007_Methods.Mol.Biol_375_165 Creation of novel enantioselective lipases by SIMPLEX 2007
Gartler_2007_J.Biotechnol_129_87 Structural determinants of the enantioselectivity of the hydroxynitrile lyase from Hevea brasiliensis 2007
Lee_2007_J.Microbiol.Biotechnol_17_74 Molecular cloning and functional expression of esf gene encoding enantioselective lipase from Serratia marcescens ES-2 for kinetic resolution of optically active (S)-flurbiprofen 2007
Hummel_2007_Angew.Chem.Int.Ed.Engl_46_8492 Isoenzymes of pig-liver esterase reveal striking differences in enantioselectivities 2007
Ivancic_2007_J.Biotechnol_129_109 Inverting enantioselectivity of Burkholderia gladioli esterase EstB by directed and designed evolution 2007
Reetz_2007_Chembiochem_8_106 Learning from directed evolution: Further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity 2007
Kourist_2007_Org.Biomol.Chem_5_3310 Identification of a metagenome-derived esterase with high enantioselectivity in the kinetic resolution of arylaliphatic tertiary alcohols 2007
Chen_2007_Wei.Sheng.Wu.Xue.Bao_47_452 [Screening of strain producing an novel esterase with high enantioselectivity and molecular cloning of the enzyme gene] 2007
Secundo_2007_Biotechnol.Bioeng_97_12 Can an inactivating agent increase enzyme activity in organic solvent? Effects of 18-crown-6 on lipase activity, enantioselectivity, and conformation 2007
Pinto_2007_Chemistry_13_961 Palladium-catalyzed enantioselective domino heck-cyanation sequence: development and application to the total synthesis of esermethole and physostigmine 2007
Leonard_2007_Chembiochem_8_662 A water molecule in the stereospecificity pocket of Candida antarctica lipase B enhances enantioselectivity towards pentan-2-ol 2007
Mosbah_2007_J.Colloid.Interface.Sci_310_196 Gly311 residue triggers the enantioselectivity of Staphylococcus xylosus lipase: a monolayer study 2007
Wu_2007_Chem.Biodivers_4_183 Environmentally friendly, efficient resolution of racemic secondary alcohols by lipase-catalyzed enantioselective transesterification in ionic liquids in the presence of organic bases 2007
Faigl_2007_Chirality_19_197 Synthesis and enantioselective rearrangement of (Z)-4-triphenylmethoxy-2,3-epoxybutan-1-ol enantiomers 2007
Mendez_2007_Chirality_19_44 Combining regio- and enantioselectivity of lipases for the preparation of (R)-4-chloro-2-butanol 2007
Kotik_2006_Biochim.Biophys.Acta_1760_245 Purification and characterisation of a novel enantioselective epoxide hydrolase from Aspergillus niger M200 2006
Reetz_2006_Angew.Chem.Int.Ed.Engl_45_1236 Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space 2006
Wu_2006_J.Org.Chem_71_5748 An expeditious enantioselective total synthesis of valilactone 2006
Bottcher_2006_Nat.Protoc_1_2340 High-throughput screening of activity and enantioselectivity of esterases 2006
Huang_2006_J.Agric.Food.Chem_54_694 Evaluation of chiral alpha-cyanoesters as general fluorescent substrates for screening enantioselective esterases 2006
Singh_2006_Bioprocess.Biosyst.Eng_28_341 Study of the experimental conditions for the lipase production by a newly isolated strain of Pseudomonas aeruginosa for the enantioselective hydrolysis of (+/-)-methyl trans-3(4-methoxyphenyl) glycidate 2006
Chen_2006_Biotechnol.Bioeng_94_201 Altering lipase activity and enantioselectivity in organic media using organo-soluble bases: Implication for rate-limiting proton transfer in acylation step 2006
Carvalho_2006_J.Ind.Microbiol.Biotechnol_33_713 Optimization of enantioselective resolution of racemic ibuprofen by native lipase from Aspergillus niger 2006
Lou_2006_J.Biotechnol_125_64 Efficient enantioselective hydrolysis of D,L-phenylglycine methyl ester catalyzed by immobilized Candida antarctica lipase B in ionic liquid containing systems 2006
Itoh_2006_Chemistry_12_9228 Increased enantioselectivity and remarkable acceleration of lipase-catalyzed transesterification by using an imidazolium PEG-alkyl sulfate ionic liquid 2006
Tsai_2006_Biochim.Biophys.Acta_1764_1424 Implication of substrate-assisted catalysis on improving lipase activity or enantioselectivity in organic solvents 2006
Schmidt_2006_Chembiochem_7_805 Directed evolution of an esterase from Pseudomonas fluorescens yields a mutant with excellent enantioselectivity and activity for the kinetic resolution of a chiral building block 2006
Romano_2005_Tetrahedron.Asymmetry_16_841 Enhanced enantioselectivity of Bacillus coagulans in the hydrolysis of 1,2-O-isopropylidene glycerol esters by thermal knock-out of undesired enzymes 2005
Zhang_2005_Artif.Cells.Blood.Substit.Immobil.Biotechnol_33_435 Purification and properties of lipases/esterases from a Bacillus strain for enantioselective resolution of (S)-Ketoprofen 2005
Mezzetti_2005_Chem.Biol_12_427 Mirror-image packing in enantiomer discrimination molecular basis for the enantioselectivity of B.cepacia lipase toward 2-methyl-3-phenyl-1-propanol 2005
Haviv_2005_J.Am.Chem.Soc_127_11029 Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase 2005
Molinari_2005_J.Appl.Microbiol_99_960 Newly isolated Streptomyces spp. as enantioselective biocatalysts: hydrolysis of 1,2-O-isopropylidene glycerol racemic esters 2005
Xin_2005_World.J.Microbiol.Biotechnol_21_193 Lipase-catalyzed naproxen methyl ester hydrolysis in water-saturated ionic liquid: significantly enhanced enantioselectivity and stability 2005
Ayers_2005_AAPS.J_7_E752 A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine 2005
Botes_2005_Syst.Appl.Microbiol_28_27 Interspecies differences in the enantioselectivity of epoxide hydrolases in Cryptococcus laurentii (Kufferath) C.E. Skinner and Cryptococcus podzolicus (Bab'jeva & Reshetova) Golubev 2005
Lee_2005_Biotechnol.Bioeng_90_223 Display of lipase on the cell surface of Escherichia coli using OprF as an anchor and its application to enantioselective resolution in organic solvent 2005
Mine_2005_Biotechnol.Lett_27_383 Enhancement of enzyme activity and enantioselectivity by cyclopentyl methyl ether in the transesterification catalyzed by Pseudomonas cepacia lipase co-lyophilized with cyclodextrins 2005
Ema_2005_Chem.Commun.(Camb)__4650 Rational control of enantioselectivity of lipase by site-directed mutagenesis based on the mechanism 2005
Rasool_2005_FEMS.Microbiol.Lett_249_113 Molecular cloning of enantioselective ester hydrolase from Bacillus pumilus DBRL-191 2005
Micaelo_2005_Biophys.J_89_999 Water dependent properties of cutinase in nonaqueous solvents: a computational study of enantioselectivity 2005
Park_2005_Chem.Biol_12_45 Focusing mutations into the P. fluorescens esterase binding site increases enantioselectivity more effectively than distant mutations 2005
van Loo_2004_Chem.Biol_11_981 Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling 2004
Reetz_2004_Org.Lett_6_177 Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution 2004
Bocola_2004_Chembiochem_5_214 Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity 2004
Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications 2004
Lee_2004_Biotechnol.Lett_26_1639 Isolation and characterization of Acinetobacter sp. ES-1 excreting a lipase with high enantioselectivity for (S)-ketoprofen ethyl ester 2004
Bicker_2004_J.Chromatogr.A_1035_37 Direct high-performance liquid chromatographic method for enantioselective and diastereoselective determination of selected pyrethroic acids 2004
Maruyama_2004_Org.Biomol.Chem_2_1239 Poly(ethylene glycol)-lipase complexes that are highly active and enantioselective in ionic liquids 2004
Secundo_2004_Biotechnol.Bioeng_86_236 Activity and enantioselectivity of wildtype and lid mutated Candida rugosa lipase isoform 1 in organic solvents 2004
Segura_2004_Biotechnol.Prog_20_825 Different properties of the lipases contained in porcine pancreatic lipase extracts as enantioselective biocatalysts 2004
Vidinha_2004_Biotechnol.Bioeng_85_442 Effect of immobilization support, water activity, and enzyme ionization state on cutinase activity and enantioselectivity in organic media 2004
Zhao_2004_J.Am.Chem.Soc_126_11156 Epoxide hydrolase-catalyzed enantioselective synthesis of chiral 1,2-diols via desymmetrization of meso-epoxides. lzhao@diversa.com 2004
Esteban_2004_Toxicol.Lett_151_243 Detection of clinical interactions between methadone and anti-retroviral compounds using an enantioselective capillary electrophoresis for methadone analysis 2004
Yu_2004_Biotechnol.Lett_26_629 Enhanced activity and enantioselectivity of Candida rugosa lipase immobilized on macroporous adsorptive resins for ibuprofen resolution 2004
Gao_2004_J.Ind.Microbiol.Biotechnol_31_525 Optimization of Serratia marcescens lipase production for enantioselective hydrolysis of 3-phenylglycidic acid ester 2004
Kijima_2004_Biotechnol.Lett_26_1505 Lipase-catalyzed enantioselective esterification of mono-aza-benzo-15-crown-5-ether derivatives in organic media 2004
Xu_2004_Appl.Microbiol.Biotechnol_66_27 Enzymatic enantioselective transcyanation of silicon-containing aliphatic ketone with (S)-hydroxynitrile lyase from Manihot esculenta 2004
Chang_2003_Chem.Commun.(Camb)__960 Highly enantioselective hydrolysis of alicyclic meso-epoxides with a bacterial epoxide hydrolase from Sphingomonas sp. HXN-200: simple syntheses of alicyclic vicinal trans-diols 2003
Han_2003_Biochimie_85_501 Expression and characterization of a novel enantioselective lipase from Acinetobacter species SY-01 2003
Horsman_2003_Chemistry_9_1933 Mutations in distant residues moderately increase the enantioselectivity of Pseudomonas fluorescens esterase towards methyl 3bromo-2-methylpropanoate and ethyl 3phenylbutyrate 2003
Choi_2003_Protein.Expr.Purif_29_85 Construction and characterization of a recombinant esterase with high activity and enantioselectivity to (S)-ketoprofen ethyl ester 2003
Du_2003_Biotechnol.Appl.Biochem_38_107 Lipase-catalysed enantioselective ammonolysis of phenylglycine methyl ester in organic solvent 2003
James_2003_Protein.Eng_16_1017 Insights from molecular dynamics simulations into pH-dependent enantioselective hydrolysis of ibuprofen esters by Candida rugosa lipase 2003
Funar-Timofei_2003_J.Chem.Inf.Comput.Sci_43_934 Quantitative structure-activity relationships for the enantioselectivity of oxirane ring-opening catalyzed by epoxide hydrolases 2003
Mine_2003_J.Biosci.Bioeng_95_441 Enhanced enzyme activity and enantioselectivity of lipases in organic solvents by crown ethers and cyclodextrins 2003
Bornscheuer_2002_Curr.Opin.Biotechnol_13_543 Methods to increase enantioselectivity of lipases and esterases 2002
Trost_2002_Angew.Chem.Int.Ed.Engl_41_2795 An efficient enantioselective synthesis of (-)-galanthamine 2002
Maqbool_2002_Biotechnol.Appl.Biochem_36_227 Purification and characterization of a novel enantioselective hydrolase from Bacillus subtilis 2002
Droge_2001_Eur.J.Biochem_268_3332 Paralogous gene analysis reveals a highly enantioselective 1,2-O-isopropylideneglycerol caprylate esterase of Bacillus subtilis 2001
Gascoyne_2001_J.Org.Chem_66_3041 Molecular basis for enantioselectivity of lipase from Chromobacterium viscosum toward the diesters of 2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol 2001
Kahlow_2001_Protein.Sci_10_1942 A model of the pressure dependence of the enantioselectivity of Candida rugosalipase towards (+/-)-menthol 2001
Jaeger_2001_Appl.Microbiol.Biotechnol_55_519 Directed evolution and the creation of enantioselective biocatalysts 2001
Kronenburga_2001_Enzyme.Microb.Technol_28_210 Effects of detergents on specific activity and enantioselectivity of the epoxide hydrolase from Rhodotorula glutinis 2001
Ottosson_2001_Protein.Sci_10_1769 Rational design of enantioselective enzymes requires considerations of entropy 2001
Rotticci_2001_Chembiochem_2_766 Improved enantioselectivity of a lipase by rational protein engineering 2001
Liebeton_2000_Chem.Biol_7_709 Directed evolution of an enantioselective lipase 2000
Tsugawa_2000_Appl.Biochem.Biotechnol_84-86_311 Improvement of enantioselectivity of chiral organophosphate insecticide hydrolysis by bacterial phosphotriesterase 2000
Sundquist_2000_Pharmacol.Toxicol_86_44 Pharmacological characterisation of the enantiomers of BM-5, a muscarinic partial agonist with opposed enantioselectivity between affinity and efficacy 2000
Jaeger_2000_Curr.Opin.Chem.Biol_4_68 Directed evolution of enantioselective enzymes for organic chemistry 2000
Reetz_2000_Pure.Appl.Chem_72_1615 Application of directed evolution in the development of enantioselective enzymes 2000
Xin_2000_Enzyme.Microb.Technol_26_137 Improvement of the enantioselectivity of lipase-catalyzed naproxen ester hydrolysis in organic solvent 2000

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