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| Title : Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125 - Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Bioorganic & Medicinal Chemistry , 19 :172 , 2011 |
| Abstract : Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| ESTHER : Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| PubMedSearch : Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| PubMedID: 21163664 |
| Title : Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554 - Banno_2011_Bioorg.Med.Chem_19_4953 |
| Author(s) : Banno Y , Miyamoto Y , Sasaki M , Oi S , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Tawada M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4953 , 2011 |
| Abstract : Banno_2011_Bioorg.Med.Chem_19_4953 |
| ESTHER : Banno_2011_Bioorg.Med.Chem_19_4953 |
| PubMedSearch : Banno_2011_Bioorg.Med.Chem_19_4953 |
| PubMedID: 21764322 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554 - Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| Author(s) : Maezaki H , Banno Y , Miyamoto Y , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Sasaki M , Tsubotani S , Tani A , Funami M , Yamamoto Y , Tawada M , Aertgeerts K , Yano J , Oi S |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4482 , 2011 |
| Abstract : Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| ESTHER : Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| PubMedSearch : Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| PubMedID: 21741847 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Design and synthesis of pyrimidinone and pyrimidinedione inhibitors of dipeptidyl peptidase IV - Zhang_2011_J.Med.Chem_54_510 |
| Author(s) : Zhang Z , Wallace MB , Feng J , Stafford JA , Skene RJ , Shi L , Lee B , Aertgeerts K , Jennings A , Xu R , Kassel DB , Kaldor SW , Navre M , Webb DR , Gwaltney SL |
| Ref : Journal of Medicinal Chemistry , 54 :510 , 2011 |
| Abstract : Zhang_2011_J.Med.Chem_54_510 |
| ESTHER : Zhang_2011_J.Med.Chem_54_510 |
| PubMedSearch : Zhang_2011_J.Med.Chem_54_510 |
| PubMedID: 21186796 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831 |
| Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Yashiro H , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Sasaki M , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Journal of Medicinal Chemistry , 54 :831 , 2011 |
| Abstract : Miyamoto_2011_J.Med.Chem_54_831 |
| ESTHER : Miyamoto_2011_J.Med.Chem_54_831 |
| PubMedSearch : Miyamoto_2011_J.Med.Chem_54_831 |
| PubMedID: 21218817 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha - Aertgeerts_2005_J.Biol.Chem_280_19441 |
| Author(s) : Aertgeerts K , Levin I , Shi L , Snell GP , Jennings A , Prasad GS , Zhang Y , Kraus ML , Salakian S , Sridhar V , Wijnands R , Tennant MG |
| Ref : Journal of Biological Chemistry , 280 :19441 , 2005 |
| Abstract : Aertgeerts_2005_J.Biol.Chem_280_19441 |
| ESTHER : Aertgeerts_2005_J.Biol.Chem_280_19441 |
| PubMedSearch : Aertgeerts_2005_J.Biol.Chem_280_19441 |
| PubMedID: 15809306 |
| Gene_locus related to this paper: human-FAP |
| Title : Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation - Aertgeerts_2004_Protein.Sci_13_412 |
| Author(s) : Aertgeerts K , Ye S , Tennant MG , Kraus ML , Rogers J , Sang BC , Skene RJ , Webb DR , Prasad GS |
| Ref : Protein Science , 13 :412 , 2004 |
| Abstract : Aertgeerts_2004_Protein.Sci_13_412 |
| ESTHER : Aertgeerts_2004_Protein.Sci_13_412 |
| PubMedSearch : Aertgeerts_2004_Protein.Sci_13_412 |
| PubMedID: 14718659 |
| Gene_locus related to this paper: human-DPP4 |
| Title : N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding - Aertgeerts_2004_Protein.Sci_13_145 |
| Author(s) : Aertgeerts K , Ye S , Shi L , Prasad SG , Witmer D , Chi E , Sang BC , Wijnands RA , Webb DR , Swanson RV |
| Ref : Protein Science , 13 :145 , 2004 |
| Abstract : Aertgeerts_2004_Protein.Sci_13_145 |
| ESTHER : Aertgeerts_2004_Protein.Sci_13_145 |
| PubMedSearch : Aertgeerts_2004_Protein.Sci_13_145 |
| PubMedID: 14691230 |