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Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__ |
Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M |
Ref : Journal of Medicinal Chemistry , : , 2021 |
Abstract : Ikeda_2021_J.Med.Chem__ |
ESTHER : Ikeda_2021_J.Med.Chem__ |
PubMedSearch : Ikeda_2021_J.Med.Chem__ |
PubMedID: 34328319 |
Gene_locus related to this paper: human-MGLL |
Title : Clinical and genetic investigation of 136 Japanese patients with congenital hypothyroidism - Tanaka_2020_J.Pediatr.Endocrinol.Metab_33_691 |
Author(s) : Tanaka T , Aoyama K , Suzuki A , Saitoh S , Mizuno H |
Ref : J Pediatr Endocrinol Metab , 33 :691 , 2020 |
Abstract : Tanaka_2020_J.Pediatr.Endocrinol.Metab_33_691 |
ESTHER : Tanaka_2020_J.Pediatr.Endocrinol.Metab_33_691 |
PubMedSearch : Tanaka_2020_J.Pediatr.Endocrinol.Metab_33_691 |
PubMedID: 32469330 |
Title : Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-((18)F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbo nyl)piperazin-1-yl]pyrrolidin-2-one ([(18)F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase - Hattori_2019_J.Med.Chem_62_2362 |
Author(s) : Hattori Y , Aoyama K , Maeda J , Arimura N , Takahashi Y , Sasaki M , Fujinaga M , Seki C , Nagai Y , Kawamura K , Yamasaki T , Zhang MR , Higuchi M , Koike T |
Ref : Journal of Medicinal Chemistry , 62 :2362 , 2019 |
Abstract : Hattori_2019_J.Med.Chem_62_2362 |
ESTHER : Hattori_2019_J.Med.Chem_62_2362 |
PubMedSearch : Hattori_2019_J.Med.Chem_62_2362 |
PubMedID: 30753069 |
Gene_locus related to this paper: human-MGLL |
Title : Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors - Aida_2018_J.Med.Chem_61_9205 |
Author(s) : Aida J , Fushimi M , Kusumoto T , Sugiyama H , Arimura N , Ikeda S , Sasaki M , Sogabe S , Aoyama K , Koike T |
Ref : Journal of Medicinal Chemistry , 61 :9205 , 2018 |
Abstract : Aida_2018_J.Med.Chem_61_9205 |
ESTHER : Aida_2018_J.Med.Chem_61_9205 |
PubMedSearch : Aida_2018_J.Med.Chem_61_9205 |
PubMedID: 30251836 |
Gene_locus related to this paper: human-MGLL |
Title : Development of rapid atrial fibrillation with a wide QRS complex after neostigmine in a patient with intermittent Wolff-Parkinson-White syndrome - Kadoya_1999_Br.J.Anaesth_83_815 |
Author(s) : Kadoya T , Seto A , Aoyama K , Takenaka I |
Ref : British Journal of Anaesthesia , 83 :815 , 1999 |
Abstract : Kadoya_1999_Br.J.Anaesth_83_815 |
ESTHER : Kadoya_1999_Br.J.Anaesth_83_815 |
PubMedSearch : Kadoya_1999_Br.J.Anaesth_83_815 |
PubMedID: 10690151 |