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Title : Poster: Low efficacy partial agonists of the alpha4\/beta2 nicotinic acetylcholine receptor (nAChR). Does functional efficacy govern in vivo response? - |
Author(s) : Coe JW , Brooks PR , Wirtz MC , Vetelino MG , Arnold EP , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley Iii FD , ONeill BT , Rollema H |
Ref : Biochemical Pharmacology , 78 :919 , 2009 |
PubMedID: |
Title : Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates--subtype selective, high affinity alpha7 nicotinic acetylcholine receptor agonists - O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
Author(s) : O'Donnell CJ , Peng L , O'Neill BT , Arnold EP , Mather RJ , Sands SB , Shrikhande A , Lebel LA , Spracklin DK , Nedza FM |
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4747 , 2009 |
Abstract : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
ESTHER : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
PubMedSearch : O'Donnell_2009_Bioorg.Med.Chem.Lett_19_4747 |
PubMedID: 19576766 |
Title : Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation - Coe_2005_J.Med.Chem_48_3474 |
Author(s) : Coe JW , Brooks PR , Vetelino MG , Wirtz MC , Arnold EP , Huang J , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Heym JH , Schaeffer E , Rollema H , Lu Y , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley FD, 3rd , O'Neill BT |
Ref : Journal of Medicinal Chemistry , 48 :3474 , 2005 |
Abstract : Coe_2005_J.Med.Chem_48_3474 |
ESTHER : Coe_2005_J.Med.Chem_48_3474 |
PubMedSearch : Coe_2005_J.Med.Chem_48_3474 |
PubMedID: 15887955 |
Title : 3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation - Coe_2005_Bioorg.Med.Chem.Lett_15_4889 |
Author(s) : Coe JW , Brooks PR , Wirtz MC , Bashore CG , Bianco KE , Vetelino MG , Arnold EP , Lebel LA , Fox CB , Tingley FD, 3rd , Schulz DW , Davis TI , Sands SB , Mansbach RS , Rollema H , O'Neill BT |
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :4889 , 2005 |
Abstract : Coe_2005_Bioorg.Med.Chem.Lett_15_4889 |
ESTHER : Coe_2005_Bioorg.Med.Chem.Lett_15_4889 |
PubMedSearch : Coe_2005_Bioorg.Med.Chem.Lett_15_4889 |
PubMedID: 16171993 |
Title : In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)-cytisine - Coe_2005_Bioorg.Med.Chem.Lett_15_2974 |
Author(s) : Coe JW , Vetelino MG , Bashore CG , Wirtz MC , Brooks PR , Arnold EP , Lebel LA , Fox CB , Sands SB , Davis TI , Schulz DW , Rollema H , Tingley FD, 3rd , O'Neill BT |
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :2974 , 2005 |
Abstract : Coe_2005_Bioorg.Med.Chem.Lett_15_2974 |
ESTHER : Coe_2005_Bioorg.Med.Chem.Lett_15_2974 |
PubMedSearch : Coe_2005_Bioorg.Med.Chem.Lett_15_2974 |
PubMedID: 15908213 |