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| Title : Preclinical Development of PNT6555, a Boronic Acid-Based, Fibroblast Activation Protein-alpha (FAP)-Targeted Radiotheranostic for Imaging and Treatment of FAP-Positive Tumors - Poplawski_2023_J.Nucl.Med__ |
| Author(s) : Poplawski SE , Hallett RM , Dornan MH , Novakowski KE , Pan S , Belanger AP , Nguyen QD , Wu W , Felten AE , Liu Y , Ahn SH , Hergott VS , Jones B , Lai JH , McCann JAB , Bachovchin WW |
| Ref : J Nucl Med , : , 2023 |
| Abstract : Poplawski_2023_J.Nucl.Med__ |
| ESTHER : Poplawski_2023_J.Nucl.Med__ |
| PubMedSearch : Poplawski_2023_J.Nucl.Med__ |
| PubMedID: 38050111 |
| Title : Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice - Panaro_2019_Mol.Metab_19_65 |
| Author(s) : Panaro BL , Coppage AL , Beaudry JL , Varin EM , Kaur K , Lai JH , Wu W , Liu Y , Bachovchin WW , Drucker DJ |
| Ref : Mol Metab , 19 :65 , 2019 |
| Abstract : Panaro_2019_Mol.Metab_19_65 |
| ESTHER : Panaro_2019_Mol.Metab_19_65 |
| PubMedSearch : Panaro_2019_Mol.Metab_19_65 |
| PubMedID: 30477988 |
| Title : DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis - Okondo_2017_Nat.Chem.Biol_13_46 |
| Author(s) : Okondo MC , Johnson DC , Sridharan R , Go EB , Chui AJ , Wang MS , Poplawski SE , Wu W , Liu Y , Lai JH , Sanford DG , Arciprete MO , Golub TR , Bachovchin WW , Bachovchin DA |
| Ref : Nat Chemical Biology , 13 :46 , 2017 |
| Abstract : Okondo_2017_Nat.Chem.Biol_13_46 |
| ESTHER : Okondo_2017_Nat.Chem.Biol_13_46 |
| PubMedSearch : Okondo_2017_Nat.Chem.Biol_13_46 |
| PubMedID: 27820798 |
| Gene_locus related to this paper: human-DPP8 , human-DPP9 |
| Title : Neuropeptide Y is a physiological substrate of fibroblast activation protein: Enzyme kinetics in blood plasma and expression of Y2R and Y5R in human liver cirrhosis and hepatocellular carcinoma - Wong_2016_Peptides_75_80 |
| Author(s) : Wong PF , Gall MG , Bachovchin WW , McCaughan GW , Keane FM , Gorrell MD |
| Ref : Peptides , 75 :80 , 2016 |
| Abstract : Wong_2016_Peptides_75_80 |
| ESTHER : Wong_2016_Peptides_75_80 |
| PubMedSearch : Wong_2016_Peptides_75_80 |
| PubMedID: 26621486 |
| Title : A pan inhibitor of DASH family enzymes induces immunogenic modulation and sensitizes murine and human carcinoma cells to antigen-specific cytotoxic T lymphocyte killing: implications for combination therapy with cancer vaccines - Donahue_2014_Vaccine_32_3223 |
| Author(s) : Donahue RN , Duncan BB , Fry TJ , Jones B , Bachovchin WW , Kiritsy CP , Lai JH , Wu W , Zhao P , Liu Y , Tsang KY , Hodge JW |
| Ref : Vaccine , :3223 , 2014 |
| Abstract : Donahue_2014_Vaccine_32_3223 |
| ESTHER : Donahue_2014_Vaccine_32_3223 |
| PubMedSearch : Donahue_2014_Vaccine_32_3223 |
| PubMedID: 24731809 |
| Title : A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity - Bachovchin_2014_Nat.Chem.Biol_10_656 |
| Author(s) : Bachovchin DA , Koblan LW , Wu W , Liu Y , Li Y , Zhao P , Woznica I , Shu Y , Lai JH , Poplawski SE , Kiritsy CP , Healey SE , DiMare M , Sanford DG , Munford RS , Bachovchin WW , Golub TR |
| Ref : Nat Chemical Biology , 10 :656 , 2014 |
| Abstract : Bachovchin_2014_Nat.Chem.Biol_10_656 |
| ESTHER : Bachovchin_2014_Nat.Chem.Biol_10_656 |
| PubMedSearch : Bachovchin_2014_Nat.Chem.Biol_10_656 |
| PubMedID: 24997602 |
| Gene_locus related to this paper: human-PPME1 |
| Title : Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs - Keane_2013_FEBS.Open.Bio_4_43 |
| Author(s) : Keane FM , Yao TW , Seelk S , Gall MG , Chowdhury S , Poplawski SE , Lai JH , Li Y , Wu W , Farrell P , Vieira de Ribeiro AJ , Osborne B , Yu DM , Seth D , Rahman K , Haber P , Topaloglu AK , Wang C , Thomson S , Hennessy A , Prins J , Twigg SM , McLennan SV , McCaughan GW , Bachovchin WW , Gorrell MD |
| Ref : FEBS Open Bio , 4 :43 , 2013 |
| Abstract : Keane_2013_FEBS.Open.Bio_4_43 |
| ESTHER : Keane_2013_FEBS.Open.Bio_4_43 |
| PubMedSearch : Keane_2013_FEBS.Open.Bio_4_43 |
| PubMedID: 24371721 |
| Title : Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase - Poplawski_2013_J.Med.Chem_56_3467 |
| Author(s) : Poplawski SE , Lai JH , Li Y , Jin Z , Liu Y , Wu W , Wu Y , Zhou Y , Sudmeier JL , Sanford DG , Bachovchin WW |
| Ref : Journal of Medicinal Chemistry , 56 :3467 , 2013 |
| Abstract : Poplawski_2013_J.Med.Chem_56_3467 |
| ESTHER : Poplawski_2013_J.Med.Chem_56_3467 |
| PubMedSearch : Poplawski_2013_J.Med.Chem_56_3467 |
| PubMedID: 23594271 |
| Title : Design and synthesis of boronic acid inhibitors of endothelial lipase - O'Connell_2012_Bioorg.Med.Chem.Lett_22_1397 |
| Author(s) : O'Connell DP , LeBlanc DF , Cromley D , Billheimer J , Rader DJ , Bachovchin WW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1397 , 2012 |
| Abstract : O'Connell_2012_Bioorg.Med.Chem.Lett_22_1397 |
| ESTHER : O'Connell_2012_Bioorg.Med.Chem.Lett_22_1397 |
| PubMedSearch : O'Connell_2012_Bioorg.Med.Chem.Lett_22_1397 |
| PubMedID: 22225633 |
| Title : 4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities - Wu_2012_Bioorg.Med.Chem.Lett_22_5536 |
| Author(s) : Wu W , Liu Y , Milo LJ, Jr. , Shu Y , Zhao P , Li Y , Woznica I , Yu G , Sanford DG , Zhou Y , Poplawski SE , Connolly BA , Sudmeier JL , Bachovchin WW , Lai JH |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :5536 , 2012 |
| Abstract : Wu_2012_Bioorg.Med.Chem.Lett_22_5536 |
| ESTHER : Wu_2012_Bioorg.Med.Chem.Lett_22_5536 |
| PubMedSearch : Wu_2012_Bioorg.Med.Chem.Lett_22_5536 |
| PubMedID: 22853995 |
| Title : Pro-soft Val-boroPro: a strategy for enhancing in vivo performance of boronic acid inhibitors of serine proteases - Poplawski_2011_J.Med.Chem_54_2022 |
| Author(s) : Poplawski SE , Lai JH , Sanford DG , Sudmeier JL , Wu W , Bachovchin WW |
| Ref : Journal of Medicinal Chemistry , 54 :2022 , 2011 |
| Abstract : Poplawski_2011_J.Med.Chem_54_2022 |
| ESTHER : Poplawski_2011_J.Med.Chem_54_2022 |
| PubMedSearch : Poplawski_2011_J.Med.Chem_54_2022 |
| PubMedID: 21388136 |
| Title : Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety - Connolly_2008_J.Med.Chem_51_6005 |
| Author(s) : Connolly BA , Sanford DG , Chiluwal AK , Healey SE , Peters DE , Dimare MT , Wu W , Liu Y , Maw H , Zhou Y , Li Y , Jin Z , Sudmeier JL , Lai JH , Bachovchin WW |
| Ref : Journal of Medicinal Chemistry , 51 :6005 , 2008 |
| Abstract : Connolly_2008_J.Med.Chem_51_6005 |
| ESTHER : Connolly_2008_J.Med.Chem_51_6005 |
| PubMedSearch : Connolly_2008_J.Med.Chem_51_6005 |
| PubMedID: 18783201 |
| Title : Synthesis and characterization of constrained peptidomimetic dipeptidyl peptidase IV inhibitors: amino-lactam boroalanines - Lai_2007_J.Med.Chem_50_2391 |
| Author(s) : Lai JH , Wu W , Zhou Y , Maw HH , Liu Y , Milo LJ, Jr. , Poplawski SE , Henry GD , Sudmeier JL , Sanford DG , Bachovchin WW |
| Ref : Journal of Medicinal Chemistry , 50 :2391 , 2007 |
| Abstract : Lai_2007_J.Med.Chem_50_2391 |
| ESTHER : Lai_2007_J.Med.Chem_50_2391 |
| PubMedSearch : Lai_2007_J.Med.Chem_50_2391 |
| PubMedID: 17458948 |
| Title : Solution structures of active and inactive forms of the DP IV (CD26) inhibitor Pro-boroPro determined by NMR spectroscopy - Sudmeier_1994_Biochemistry_33_12427 |
| Author(s) : Sudmeier JL , Gunther UL , Gutheil WG , Coutts SJ , Snow RJ , Barton RW , Bachovchin WW |
| Ref : Biochemistry , 33 :12427 , 1994 |
| Abstract : Sudmeier_1994_Biochemistry_33_12427 |
| ESTHER : Sudmeier_1994_Biochemistry_33_12427 |
| PubMedSearch : Sudmeier_1994_Biochemistry_33_12427 |
| PubMedID: 7918465 |
| Title : Dipeptidyl peptidase IV (DP IV) activity in serum and on lymphocytes of MRL\/Mp-lpr\/lpr mice correlates with disease onset - Kubota_1994_Clin.Exp.Immunol_96_292 |
| Author(s) : Kubota T , Iizuka H , Bachovchin WW , Stollar BD |
| Ref : Clinical & Experimental Immunology , 96 :292 , 1994 |
| Abstract : Kubota_1994_Clin.Exp.Immunol_96_292 |
| ESTHER : Kubota_1994_Clin.Exp.Immunol_96_292 |
| PubMedSearch : Kubota_1994_Clin.Exp.Immunol_96_292 |
| PubMedID: 7910536 |
| Title : Separation of L-Pro-DL-boroPro into its component diastereomers and kinetic analysis of their inhibition of dipeptidyl peptidase IV. A new method for the analysis of slow, tight-binding inhibition - Gutheil_1993_Biochemistry_32_8723 |
| Author(s) : Gutheil WG , Bachovchin WW |
| Ref : Biochemistry , 32 :8723 , 1993 |
| Abstract : Gutheil_1993_Biochemistry_32_8723 |
| ESTHER : Gutheil_1993_Biochemistry_32_8723 |
| PubMedSearch : Gutheil_1993_Biochemistry_32_8723 |
| PubMedID: 8103356 |