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| Title : alpha7 Nicotinic Receptor Agonist Enhances Cognition in Aged 3xTg-AD Mice with Robust Plaques and Tangles - Medeiros_2014_Am.J.Pathol_184_520 |
| Author(s) : Medeiros R , Castello NA , Cheng D , Kitazawa M , Baglietto-Vargas D , Green KN , Esbenshade TA , Bitner RS , Decker MW , LaFerla FM |
| Ref : American Journal of Pathology , 184 :520 , 2014 |
| Abstract : Medeiros_2014_Am.J.Pathol_184_520 |
| ESTHER : Medeiros_2014_Am.J.Pathol_184_520 |
| PubMedSearch : Medeiros_2014_Am.J.Pathol_184_520 |
| PubMedID: 24269557 |
| Title : Effects of alpha7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis - Kohlhaas_2012_Psychopharmacology.(Berl)_220_823 |
| Author(s) : Kohlhaas KL , Bitner RS , Gopalakrishnan M , Rueter LE |
| Ref : Psychopharmacology (Berl) , 220 :823 , 2012 |
| Abstract : Kohlhaas_2012_Psychopharmacology.(Berl)_220_823 |
| ESTHER : Kohlhaas_2012_Psychopharmacology.(Berl)_220_823 |
| PubMedSearch : Kohlhaas_2012_Psychopharmacology.(Berl)_220_823 |
| PubMedID: 22038534 |
| Title : Effects of the novel alpha7 nicotinic acetylcholine receptor agonist ABT-107 on sensory gating in DBA\/2 mice: pharmacodynamic characterization - Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| Author(s) : Radek RJ , Robb HM , Stevens KE , Gopalakrishnan M , Bitner RS |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 343 :736 , 2012 |
| Abstract : Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| ESTHER : Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| PubMedSearch : Radek_2012_J.Pharmacol.Exp.Ther_343_736 |
| PubMedID: 22988063 |
| Title : Poster: alpha7 NNR allosteric modulation in behavioral models of cognition - |
| Author(s) : Kohlhaas KL , Robb H , Roderwald V , Markosyan S , Salte K , Bitner RS , Mohler E , Terry AV, Jr. , Buccafusco JJ , Rueter LE , Lee L , Gopalakrishnan M |
| Ref : Biochemical Pharmacology , 82 :1042 , 2011 |
| PubMedID: |
| Title : In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease - Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| Author(s) : Bitner RS , Bunnelle WH , Decker MW , Drescher KU , Kohlhaas KL , Markosyan S , Marsh KC , Nikkel AL , Browman K , Radek R , Anderson DJ , Buccafusco JJ , Gopalakrishnan M |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :875 , 2010 |
| Abstract : Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| ESTHER : Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| PubMedSearch : Bitner_2010_J.Pharmacol.Exp.Ther_334_875 |
| PubMedID: 20504913 |
| Title : Selective alpha7 nicotinic acetylcholine receptor activation regulates glycogen synthase kinase3beta and decreases tau phosphorylation in vivo - Bitner_2009_Brain.Res_1265_65 |
| Author(s) : Bitner RS , Nikkel AL , Markosyan S , Otte S , Puttfarcken P , Gopalakrishnan M |
| Ref : Brain Research , 1265 :65 , 2009 |
| Abstract : Bitner_2009_Brain.Res_1265_65 |
| ESTHER : Bitner_2009_Brain.Res_1265_65 |
| PubMedSearch : Bitner_2009_Brain.Res_1265_65 |
| PubMedID: 19230830 |
| Title : Poster: Profile of A-716096, a novel thiazolylidine positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor - |
| Author(s) : Donnelly-Roberts D , Malysz J , Faghih R , Gronlien H , Haakerud M , Thorin-Hagne K , Ween H , Gopalakrishnan SM , Hu M , Li J , Anderson DJ , Kohlhaas KL , Namovic M , Radek R , Robb H , Briggs CA , Bitner RS , Bunnelle WH , Gopalakrishnan M |
| Ref : Biochemical Pharmacology , 78 :912 , 2009 |
| PubMedID: |
| Title : Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties - Tietje_2008_CNS.Neurosci.Ther_14_65 |
| Author(s) : Tietje KR , Anderson DJ , Bitner RS , Blomme EA , Brackemeyer PJ , Briggs CA , Browman KE , Bury D , Curzon P , Drescher KU , Frost JM , Fryer RM , Fox GB , Gronlien JH , Hakerud M , Gubbins EJ , Halm S , Harris R , Helfrich RJ , Kohlhaas KL , Law D , Malysz J , Marsh KC , Martin RL , Meyer MD , Molesky AL , Nikkel AL , Otte S , Pan L , Puttfarcken PS , Radek RJ , Robb HM , Spies E , Thorin-Hagene K , Waring JF , Ween H , Xu H , Gopalakrishnan M , Bunnelle WH |
| Ref : CNS Neurosci Ther , 14 :65 , 2008 |
| Abstract : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| ESTHER : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedSearch : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedID: 18482100 |
| Title : Analysis of gene expression profiles in rat hippocampus following treatment with nicotine and an alpha7 nAChR selective agonist - Waring_2008_Neurosci.Res_60_266 |
| Author(s) : Waring JF , Abel S , Li J , Bitner RS , Nikkel AL , Blomme EA , Anderson DJ , Gopalakrishnan M |
| Ref : Neurosci Res , 60 :266 , 2008 |
| Abstract : Waring_2008_Neurosci.Res_60_266 |
| ESTHER : Waring_2008_Neurosci.Res_60_266 |
| PubMedSearch : Waring_2008_Neurosci.Res_60_266 |
| PubMedID: 18164502 |
| Title : Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1\/2 and CREB phosphorylation pathways - Bitner_2007_J.Neurosci_27_10578 |
| Author(s) : Bitner RS , Bunnelle WH , Anderson DJ , Briggs CA , Buccafusco JJ , Curzon P , Decker MW , Frost JM , Gronlien JH , Gubbins E , Li J , Malysz J , Markosyan S , Marsh K , Meyer MD , Nikkel AL , Radek RJ , Robb HM , Timmermann DB , Sullivan JP , Gopalakrishnan M |
| Ref : Journal of Neuroscience , 27 :10578 , 2007 |
| Abstract : Bitner_2007_J.Neurosci_27_10578 |
| ESTHER : Bitner_2007_J.Neurosci_27_10578 |
| PubMedSearch : Bitner_2007_J.Neurosci_27_10578 |
| PubMedID: 17898229 |
| Title : Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment - Curzon_2006_Neurosci.Lett_410_15 |
| Author(s) : Curzon P , Anderson DJ , Nikkel AL , Fox GB , Gopalakrishnan M , Decker MW , Bitner RS |
| Ref : Neuroscience Letters , 410 :15 , 2006 |
| Abstract : Curzon_2006_Neurosci.Lett_410_15 |
| ESTHER : Curzon_2006_Neurosci.Lett_410_15 |
| PubMedSearch : Curzon_2006_Neurosci.Lett_410_15 |
| PubMedID: 17055644 |
| Title : Alpha4beta2 nicotinic receptor stimulation contributes to the effects of nicotine in the DBA\/2 mouse model of sensory gating - Radek_2006_Psychopharmacology.(Berl)_187_47 |
| Author(s) : Radek RJ , Miner HM , Bratcher NA , Decker MW , Gopalakrishnan M , Bitner RS |
| Ref : Psychopharmacology (Berl) , 187 :47 , 2006 |
| Abstract : Radek_2006_Psychopharmacology.(Berl)_187_47 |
| ESTHER : Radek_2006_Psychopharmacology.(Berl)_187_47 |
| PubMedSearch : Radek_2006_Psychopharmacology.(Berl)_187_47 |
| PubMedID: 16767415 |
| Title : A-85380: a pharmacological probe for the preclinical and clinical investigation of the alphabeta neuronal nicotinic acetylcholine receptor - Rueter_2006_CNS.Drug.Rev_12_100 |
| Author(s) : Rueter LE , Donnelly-Roberts D , Curzon P , Briggs CA , Anderson DJ , Bitner RS |
| Ref : CNS Drug Rev , 12 :100 , 2006 |
| Abstract : Rueter_2006_CNS.Drug.Rev_12_100 |
| ESTHER : Rueter_2006_CNS.Drug.Rev_12_100 |
| PubMedSearch : Rueter_2006_CNS.Drug.Rev_12_100 |
| PubMedID: 16958984 |
| Title : In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide - Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| Author(s) : Adams MR , Nikkel AL , Donnelly-Roberts D , Watt AT , Johnston JF , Cowsert LM , Butler M , Kroeger PE , Frost L , Curzon P , Decker MW , Bitner RS |
| Ref : Brain Research Mol Brain Res , 129 :67 , 2004 |
| Abstract : Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| ESTHER : Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| PubMedSearch : Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| PubMedID: 15469883 |
| Title : Neuronal nicotinic receptors: filling the void? - |
| Author(s) : Gopalakrishnan M , Bitner RS |
| Ref : American Journal of Physiology Regul Integr Comp Physiol , 285 :R21 , 2003 |
| PubMedID: 12793987 |
| Title : Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat - Bitner_2000_Brain.Res_871_66 |
| Author(s) : Bitner RS , Nikkel AL , Curzon P , Donnelly-Roberts D , Puttfarcken PS , Namovic M , Jacobs IC , Meyer MD , Decker MW |
| Ref : Brain Research , 871 :66 , 2000 |
| Abstract : Bitner_2000_Brain.Res_871_66 |
| ESTHER : Bitner_2000_Brain.Res_871_66 |
| PubMedSearch : Bitner_2000_Brain.Res_871_66 |
| PubMedID: 10882784 |
| Title : Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors - Bannon_1998_Science_279_77 |
| Author(s) : Bannon AW , Decker MW , Holladay MW , Curzon P , Donnelly-Roberts D , Puttfarcken PS , Bitner RS , Diaz A , Dickenson AH , Porsolt RD , Williams M , Arneric SP |
| Ref : Science , 279 :77 , 1998 |
| Abstract : Bannon_1998_Science_279_77 |
| ESTHER : Bannon_1998_Science_279_77 |
| PubMedSearch : Bannon_1998_Science_279_77 |
| PubMedID: 9417028 |
| Title : The role of neuronal nicotinic acetylcholine receptors in antinociception: effects of ABT-594 - Decker_1998_J.Physiol.Paris_92_221 |
| Author(s) : Decker MW , Curzon P , Holladay MW , Nikkel AL , Bitner RS , Bannon AW , Donnelly-Roberts D , Puttfarcken PS , Kuntzweiler TA , Briggs CA , Williams M , Arneric SP |
| Ref : Journal de Physiologie (Paris) , 92 :221 , 1998 |
| Abstract : Decker_1998_J.Physiol.Paris_92_221 |
| ESTHER : Decker_1998_J.Physiol.Paris_92_221 |
| PubMedSearch : Decker_1998_J.Physiol.Paris_92_221 |
| PubMedID: 9789812 |