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| Title : Dual Soluble Epoxide Hydrolase Inhibitor\/PPAR-gamma Agonist Attenuates Renal Fibrosis - Stavniichuk_2020_Prostaglandins.Other.Lipid.Mediat__106472 |
| Author(s) : Stavniichuk A , Hye Khan MA , Yeboah MM , Chesnik MA , Jankiewicz WK , Hartmann M , Blocher R , Kircher T , Savchuk O , Proschak E , Imig JD |
| Ref : Prostaglandins Other Lipid Mediat , :106472 , 2020 |
| Abstract : Stavniichuk_2020_Prostaglandins.Other.Lipid.Mediat__106472 |
| ESTHER : Stavniichuk_2020_Prostaglandins.Other.Lipid.Mediat__106472 |
| PubMedSearch : Stavniichuk_2020_Prostaglandins.Other.Lipid.Mediat__106472 |
| PubMedID: 32569747 |
| Title : Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase - Hiesinger_2020_ACS.Med.Chem.Lett_11_298 |
| Author(s) : Hiesinger K , Schott A , Kramer JS , Blocher R , Witt F , Wittmann SK , Steinhilber D , Pogoryelov D , Gerstmeier J , Werz O , Proschak E |
| Ref : ACS Med Chem Lett , 11 :298 , 2020 |
| Abstract : Hiesinger_2020_ACS.Med.Chem.Lett_11_298 |
| ESTHER : Hiesinger_2020_ACS.Med.Chem.Lett_11_298 |
| PubMedSearch : Hiesinger_2020_ACS.Med.Chem.Lett_11_298 |
| PubMedID: 32184960 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea - Wan_2019_Front.Pharmacol_10_464 |
| Author(s) : Wan D , Yang J , McReynolds CB , Barnych B , Wagner KM , Morisseau C , Hwang SH , Sun J , Blocher R , Hammock BD |
| Ref : Front Pharmacol , 10 :464 , 2019 |
| Abstract : Wan_2019_Front.Pharmacol_10_464 |
| ESTHER : Wan_2019_Front.Pharmacol_10_464 |
| PubMedSearch : Wan_2019_Front.Pharmacol_10_464 |
| PubMedID: 31143115 |
| Title : Orally Available Soluble Epoxide Hydrolase\/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain - Blocher_2018_J.Med.Chem_61_3541 |
| Author(s) : Blocher R , Wagner KM , Gopireddy RR , Harris TR , Wu H , Barnych B , Hwang SH , Xiang YK , Proschak E , Morisseau C , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 61 :3541 , 2018 |
| Abstract : Blocher_2018_J.Med.Chem_61_3541 |
| ESTHER : Blocher_2018_J.Med.Chem_61_3541 |
| PubMedSearch : Blocher_2018_J.Med.Chem_61_3541 |
| PubMedID: 29614224 |
| Title : Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase - Meirer_2016_Molecules_22_ |
| Author(s) : Meirer K , Glatzel D , Kretschmer S , Wittmann SK , Hartmann M , Blocher R , Angioni C , Geisslinger G , Steinhilber D , Hofmann B , Furst R , Proschak E |
| Ref : Molecules , 22 : , 2016 |
| Abstract : Meirer_2016_Molecules_22_ |
| ESTHER : Meirer_2016_Molecules_22_ |
| PubMedSearch : Meirer_2016_Molecules_22_ |
| PubMedID: 28036068 |
| Title : N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase\/Peroxisome Proliferator-Activated Receptor gamma Modulators - Blocher_2016_J.Med.Chem_59_61 |
| Author(s) : Blocher R , Lamers C , Wittmann SK , Merk D , Hartmann M , Weizel L , Diehl O , Bruggerhoff A , Boss M , Kaiser A , Schader T , Gobel T , Grundmann M , Angioni C , Heering J , Geisslinger G , Wurglics M , Kostenis E , Brune B , Steinhilber D , Schubert-Zsilavecz M , Kahnt AS , Proschak E |
| Ref : Journal of Medicinal Chemistry , 59 :61 , 2016 |
| Abstract : Blocher_2016_J.Med.Chem_59_61 |
| ESTHER : Blocher_2016_J.Med.Chem_59_61 |
| PubMedSearch : Blocher_2016_J.Med.Chem_59_61 |
| PubMedID: 26595749 |
| Title : Exploring the chemical space of multitarget ligands using aligned self-organizing maps - Achenbach_2013_ACS.Med.Chem.Lett_4_1169 |
| Author(s) : Achenbach J , Klingler FM , Blocher R , Moser D , Hafner AK , Rodl CB , Kretschmer S , Kruger B , Lohr F , Stark H , Hofmann B , Steinhilber D , Proschak E |
| Ref : ACS Med Chem Lett , 4 :1169 , 2013 |
| Abstract : Achenbach_2013_ACS.Med.Chem.Lett_4_1169 |
| ESTHER : Achenbach_2013_ACS.Med.Chem.Lett_4_1169 |
| PubMedSearch : Achenbach_2013_ACS.Med.Chem.Lett_4_1169 |
| PubMedID: 24900624 |