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| Title : Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625\/WYE-103914) - Ghiron_2010_J.Med.Chem_53_4379 |
| Author(s) : Ghiron C , Haydar SN , Aschmies S , Bothmann H , Castaldo C , Cocconcelli G , Comery TA , Di L , Dunlop J , Lock T , Kramer A , Kowal D , Jow F , Grauer S , Harrison B , La Rosa S , Maccari L , Marquis KL , Micco I , Nencini A , Quinn J , Robichaud AJ , Roncarati R , Scali C , Terstappen GC , Turlizzi E , Valacchi M , Varrone M , Zanaletti R , Zanelli U |
| Ref : Journal of Medicinal Chemistry , 53 :4379 , 2010 |
| Abstract : Ghiron_2010_J.Med.Chem_53_4379 |
| ESTHER : Ghiron_2010_J.Med.Chem_53_4379 |
| PubMedSearch : Ghiron_2010_J.Med.Chem_53_4379 |
| PubMedID: 20465311 |
| Title : SAR and biological evaluation of SEN12333\/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist - Haydar_2009_Bioorg.Med.Chem_17_5247 |
| Author(s) : Haydar SN , Ghiron C , Bettinetti L , Bothmann H , Comery TA , Dunlop J , La Rosa S , Micco I , Pollastrini M , Quinn J , Roncarati R , Scali C , Valacchi M , Varrone M , Zanaletti R |
| Ref : Bioorganic & Medicinal Chemistry , 17 :5247 , 2009 |
| Abstract : Haydar_2009_Bioorg.Med.Chem_17_5247 |
| ESTHER : Haydar_2009_Bioorg.Med.Chem_17_5247 |
| PubMedSearch : Haydar_2009_Bioorg.Med.Chem_17_5247 |
| PubMedID: 19515567 |
| Title : Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders - Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| Author(s) : Roncarati R , Scali C , Comery TA , Grauer SM , Aschmi S , Bothmann H , Jow B , Kowal D , Gianfriddo M , Kelley C , Zanelli U , Ghiron C , Haydar S , Dunlop J , Terstappen GC |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 329 :459 , 2009 |
| Abstract : Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| ESTHER : Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| PubMedSearch : Roncarati_2009_J.Pharmacol.Exp.Ther_329_459 |
| PubMedID: 19223665 |
| Title : Functional properties of alpha7 nicotinic acetylcholine receptors co-expressed with RIC-3 in a stable recombinant CHO-K1 cell line - Roncarati_2008_Assay.Drug.Dev.Technol_6_181 |
| Author(s) : Roncarati R , Seredenina T , Jow B , Jow F , Papini S , Kramer A , Bothmann H , Dunlop J , Terstappen GC |
| Ref : Assay Drug Dev Technol , 6 :181 , 2008 |
| Abstract : Roncarati_2008_Assay.Drug.Dev.Technol_6_181 |
| ESTHER : Roncarati_2008_Assay.Drug.Dev.Technol_6_181 |
| PubMedSearch : Roncarati_2008_Assay.Drug.Dev.Technol_6_181 |
| PubMedID: 18471073 |
| Title : In vitro screening strategies for nicotinic receptor ligands - Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| Author(s) : Dunlop J , Roncarati R , Jow B , Bothmann H , Lock T , Kowal D , Bowlby M , Terstappen GC |
| Ref : Biochemical Pharmacology , 74 :1172 , 2007 |
| Abstract : Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| ESTHER : Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| PubMedSearch : Dunlop_2007_Biochem.Pharmacol_74(8)_1172 |
| PubMedID: 17706607 |