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| Title : Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes - Grabner_2022_J.Am.Chem.Soc__ |
| Author(s) : Grabner GF , Guttenberger N , Mayer N , Migglautsch-Sulzer AK , Lembacher-Fadum C , Fawzy N , Bulfon D , Hofer P , Zullig T , Hartig L , Kulminskaya N , Chalhoub G , Schratter M , Radner FPW , Preiss-Landl K , Masser S , Lass A , Zechner R , Gruber K , Oberer M , Breinbauer R , Zimmermann R |
| Ref : Journal of the American Chemical Society , : , 2022 |
| Abstract : Grabner_2022_J.Am.Chem.Soc__ |
| ESTHER : Grabner_2022_J.Am.Chem.Soc__ |
| PubMedSearch : Grabner_2022_J.Am.Chem.Soc__ |
| PubMedID: 35362954 |
| Title : Structural Changes in the Cap of Rv0183\/mtbMGL Modulate the Shape of the Binding Pocket - Grininger_2021_Biomolecules_11_1299 |
| Author(s) : Grininger C , Leypold M , Aschauer P , Pavkov-Keller T , Riegler-Berket L , Breinbauer R , Oberer M |
| Ref : Biomolecules , 11 :1299 , 2021 |
| Abstract : Grininger_2021_Biomolecules_11_1299 |
| ESTHER : Grininger_2021_Biomolecules_11_1299 |
| PubMedSearch : Grininger_2021_Biomolecules_11_1299 |
| PubMedID: 34572512 |
| Gene_locus related to this paper: myctu-rv0183 |
| Title : Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL) - Mayer_2020_Bioorg.Med.Chem_28_115610 |
| Author(s) : Mayer N , Schweiger M , Fuchs E , Migglautsch AK , Doler C , Grabner GF , Romauch M , Melcher MC , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Bioorganic & Medicinal Chemistry , 28 :115610 , 2020 |
| Abstract : Mayer_2020_Bioorg.Med.Chem_28_115610 |
| ESTHER : Mayer_2020_Bioorg.Med.Chem_28_115610 |
| PubMedSearch : Mayer_2020_Bioorg.Med.Chem_28_115610 |
| PubMedID: 32690265 |
| Title : Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans - Grabner_2019_J.Lipid.Res_60_1020 |
| Author(s) : Grabner GF , Fawzy N , Pribasnig MA , Trieb M , Taschler U , Holzer M , Schweiger M , Wolinski H , Kolb D , Horvath A , Breinbauer R , Rulicke T , Rabl R , Lass A , Stadlbauer V , Hutter-Paier B , Stauber RE , Fickert P , Zechner R , Marsche G , Eichmann TO , Zimmermann R |
| Ref : J Lipid Res , 60 :1020 , 2019 |
| Abstract : Grabner_2019_J.Lipid.Res_60_1020 |
| ESTHER : Grabner_2019_J.Lipid.Res_60_1020 |
| PubMedSearch : Grabner_2019_J.Lipid.Res_60_1020 |
| PubMedID: 30894461 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition - Aschauer_2018_Sci.Rep_8_8948 |
| Author(s) : Aschauer P , Zimmermann R , Breinbauer R , Pavkov-Keller T , Oberer M |
| Ref : Sci Rep , 8 :8948 , 2018 |
| Abstract : Aschauer_2018_Sci.Rep_8_8948 |
| ESTHER : Aschauer_2018_Sci.Rep_8_8948 |
| PubMedSearch : Aschauer_2018_Sci.Rep_8_8948 |
| PubMedID: 29895832 |
| Gene_locus related to this paper: myctu-rv0183 |
| Title : Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice - Schweiger_2017_Nat.Commun_8_14859 |
| Author(s) : Schweiger M , Romauch M , Schreiber R , Grabner GF , Hutter S , Kotzbeck P , Benedikt P , Eichmann TO , Yamada S , Knittelfelder O , Diwoky C , Doler C , Mayer N , De Cecco W , Breinbauer R , Zimmermann R , Zechner R |
| Ref : Nat Commun , 8 :14859 , 2017 |
| Abstract : Schweiger_2017_Nat.Commun_8_14859 |
| ESTHER : Schweiger_2017_Nat.Commun_8_14859 |
| PubMedSearch : Schweiger_2017_Nat.Commun_8_14859 |
| PubMedID: 28327588 |
| Title : Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p - Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| Author(s) : Aschauer P , Rengachari S , Lichtenegger J , Schittmayer M , Das KM , Mayer N , Breinbauer R , Birner-Gruenberger R , Gruber CC , Zimmermann R , Gruber K , Oberer M |
| Ref : Biochimica & Biophysica Acta , 1861 :462 , 2016 |
| Abstract : Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| ESTHER : Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| PubMedSearch : Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| PubMedID: 26869448 |
| Gene_locus related to this paper: yeast-mgll |
| Title : Enzymatic hydrolysis of poly(ethylene furanoate) - Pellis_2016_J.Biotechnol_235_47 |
| Author(s) : Pellis A , Haernvall K , Pichler CM , Ghazaryan G , Breinbauer R , Guebitz GM |
| Ref : J Biotechnol , 235 :47 , 2016 |
| Abstract : Pellis_2016_J.Biotechnol_235_47 |
| ESTHER : Pellis_2016_J.Biotechnol_235_47 |
| PubMedSearch : Pellis_2016_J.Biotechnol_235_47 |
| PubMedID: 26854948 |
| Gene_locus related to this paper: thefu-q6a0i4 |
| Title : A robust and simple protocol for the synthesis of arylfluorophosphonates - Leypold_2015_Tetrahedron.Lett_56_5619 |
| Author(s) : Leypold M , Wallace PW , Kljajic M , Schittmayer M , Pletz J , Illaszewicz-Trattner C , Guebitz GM , Birner-Gruenberger R , Breinbauer R |
| Ref : Tetrahedron Letters , 56 :5619 , 2015 |
| Abstract : Leypold_2015_Tetrahedron.Lett_56_5619 |
| ESTHER : Leypold_2015_Tetrahedron.Lett_56_5619 |
| PubMedSearch : Leypold_2015_Tetrahedron.Lett_56_5619 |
| PubMedID: |
| Title : alpha\/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal\/Lysosomal Lipid Bis(monoacylglycero)phosphate - Pribasnig_2015_J.Biol.Chem_290_29869 |
| Author(s) : Pribasnig MA , Mrak I , Grabner GF , Taschler U , Knittelfelder O , Scherz B , Eichmann TO , Heier C , Grumet L , Kowaliuk J , Romauch M , Holler S , Anderl F , Wolinski H , Lass A , Breinbauer R , Marsche G , Brown JM , Zimmermann R |
| Ref : Journal of Biological Chemistry , 290 :29869 , 2015 |
| Abstract : Pribasnig_2015_J.Biol.Chem_290_29869 |
| ESTHER : Pribasnig_2015_J.Biol.Chem_290_29869 |
| PubMedSearch : Pribasnig_2015_J.Biol.Chem_290_29869 |
| PubMedID: 26491015 |
| Gene_locus related to this paper: human-ABHD6 |
| Title : Biocatalyzed approach for the surface functionalization of poly(L-lactic acid) films using hydrolytic enzymes - Pellis_2015_Biotechnol.J_10_1739 |
| Author(s) : Pellis A , Herrero Acero E , Weber H , Obersriebnig M , Breinbauer R , Srebotnik E , Guebitz GM |
| Ref : Biotechnol J , 10 :1739 , 2015 |
| Abstract : Pellis_2015_Biotechnol.J_10_1739 |
| ESTHER : Pellis_2015_Biotechnol.J_10_1739 |
| PubMedSearch : Pellis_2015_Biotechnol.J_10_1739 |
| PubMedID: 25963883 |
| Title : Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells - Taschler_2015_Biochim.Biophys.Acta_1851_937 |
| Author(s) : Taschler U , Schreiber R , Chitraju C , Grabner GF , Romauch M , Wolinski H , Haemmerle G , Breinbauer R , Zechner R , Lass A , Zimmermann R |
| Ref : Biochimica & Biophysica Acta , 1851 :937 , 2015 |
| Abstract : Taschler_2015_Biochim.Biophys.Acta_1851_937 |
| ESTHER : Taschler_2015_Biochim.Biophys.Acta_1851_937 |
| PubMedSearch : Taschler_2015_Biochim.Biophys.Acta_1851_937 |
| PubMedID: 25732851 |
| Title : Weighing the proteasome for covalent modifications - Birner-Gruenberger_2015_Chem.Biol_22_315 |
| Author(s) : Birner-Gruenberger R , Breinbauer R |
| Ref : Chemical Biology , 22 :315 , 2015 |
| Abstract : Birner-Gruenberger_2015_Chem.Biol_22_315 |
| ESTHER : Birner-Gruenberger_2015_Chem.Biol_22_315 |
| PubMedSearch : Birner-Gruenberger_2015_Chem.Biol_22_315 |
| PubMedID: 25794435 |
| Title : Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling - Hofer_2015_J.Biol.Chem_290_18438 |
| Author(s) : Hofer P , Boeszoermenyi A , Jaeger D , Feiler U , Arthanari H , Mayer N , Zehender F , Rechberger G , Oberer M , Zimmermann R , Lass A , Haemmerle G , Breinbauer R , Zechner R , Preiss-Landl K |
| Ref : Journal of Biological Chemistry , 290 :18438 , 2015 |
| Abstract : Hofer_2015_J.Biol.Chem_290_18438 |
| ESTHER : Hofer_2015_J.Biol.Chem_290_18438 |
| PubMedSearch : Hofer_2015_J.Biol.Chem_290_18438 |
| PubMedID: 25953897 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL) - Mayer_2015_Bioorg.Med.Chem_23_2904 |
| Author(s) : Mayer N , Schweiger M , Melcher MC , Fledelius C , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Bioorganic & Medicinal Chemistry , 23 :2904 , 2015 |
| Abstract : Mayer_2015_Bioorg.Med.Chem_23_2904 |
| ESTHER : Mayer_2015_Bioorg.Med.Chem_23_2904 |
| PubMedSearch : Mayer_2015_Bioorg.Med.Chem_23_2904 |
| PubMedID: 25778769 |
| Title : Development of small-molecule inhibitors targeting adipose triglyceride lipase - Mayer_2013_Nat.Chem.Biol_9_785 |
| Author(s) : Mayer N , Schweiger M , Romauch M , Grabner GF , Eichmann TO , Fuchs E , Ivkovic J , Heier C , Mrak I , Lass A , Hofler G , Fledelius C , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Nat Chemical Biology , 9 :785 , 2013 |
| Abstract : Mayer_2013_Nat.Chem.Biol_9_785 |
| ESTHER : Mayer_2013_Nat.Chem.Biol_9_785 |
| PubMedSearch : Mayer_2013_Nat.Chem.Biol_9_785 |
| PubMedID: 24096302 |
| Title : Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase - Rengachari_2013_J.Biol.Chem_288_31093 |
| Author(s) : Rengachari S , Aschauer P , Schittmayer M , Mayer N , Gruber K , Breinbauer R , Birner-Gruenberger R , Dreveny I , Oberer M |
| Ref : Journal of Biological Chemistry , 288 :31093 , 2013 |
| Abstract : Rengachari_2013_J.Biol.Chem_288_31093 |
| ESTHER : Rengachari_2013_J.Biol.Chem_288_31093 |
| PubMedSearch : Rengachari_2013_J.Biol.Chem_288_31093 |
| PubMedID: 24014019 |
| Gene_locus related to this paper: bac25-mglp |
| Title : Protein structure similarity as guiding principle for combinatorial library design - Koch_2003_Biol.Chem_384_1265 |
| Author(s) : Koch MA , Breinbauer R , Waldmann H |
| Ref : Biol Chem , 384 :1265 , 2003 |
| Abstract : Koch_2003_Biol.Chem_384_1265 |
| ESTHER : Koch_2003_Biol.Chem_384_1265 |
| PubMedSearch : Koch_2003_Biol.Chem_384_1265 |
| PubMedID: 14515987 |