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Author Report for: Carr PD

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    Title: The Synthesis of Certain Derivatives and Analogues of (-)- and (+)-Galanthamine and an Assessment of their Capacities to Inhibit Acetylcholine Esterase
    Buckler JN, Taher ES, Fraser NJ, Willis AC, Carr PD, Jackson CJ, Banwell MG
    Ref: J Org Chem, 82:7869, 2017 : PubMed

            

    Title: Structure of an Insecticide Sequestering Carboxylesterase from the Disease Vector Culex quinquefasciatus: What Makes an Enzyme a Good Insecticide Sponge?
    Hopkins DH, Fraser NJ, Mabbitt PD, Carr PD, Oakeshott JG, Jackson CJ
    Ref: Biochemistry, 56:5512, 2017 : PubMed

            

    Title: The role of protein dynamics in the evolution of new enzyme function
    Campbell EC, Kaltenbach M, Correy GJ, Carr PD, Porebski BT, Livingstone EK, Afriat-Jurnou L, Buckle AM, Weik M and Jackson CJ <2 more author(s)>
    Ref: Nat Chemical Biology, 12:944, 2016 : PubMed

            

    Title: Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography
    Correy GJ, Carr PD, Meirelles T, Mabbitt PD, Fraser NJ, Weik M, Jackson CJ
    Ref: Structure, 24:977, 2016 : PubMed

            

    Title: Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron
    Sugrue E, Fraser NJ, Hopkins DH, Carr PD, Khurana JL, Oakeshott JG, Scott C, Jackson CJ
    Ref: Applied Environmental Microbiology, 81:2612, 2015 : PubMed

            

    Title: A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis
    Naqvi T, Warden AC, French N, Sugrue E, Carr PD, Jackson CJ, Scott C
    Ref: PLoS ONE, 9:e94177, 2014 : PubMed

            

    Title: Crystallization of dienelactone hydrolase in two space groups: structural changes caused by crystal packing
    Porter JL, Carr PD, Collyer CA, Ollis DL
    Ref: Acta Crystallographica F Struct Biol Commun, 70:884, 2014 : PubMed

            

    Title: Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance
    Jackson CJ, Liu JW, Carr PD, Younus F, Coppin C, Meirelles T, Lethier M, Pandey G, Ollis DL and Oakeshott JG <2 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 110:10177, 2013 : PubMed

            

    Title: Alpha/beta hydrolase fold: an update
    Carr PD, Ollis DL
    Ref: Protein Pept Lett, 16:1137, 2009 : PubMed

            

    Title: In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase
    Jackson CJ, Foo JL, Kim HK, Carr PD, Liu JW, Salem G, Ollis DL
    Ref: Journal of Molecular Biology, 375:1189, 2008 : PubMed

            

    Title: Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase
    Kim HK, Liu JW, Carr PD, Ollis DL
    Ref: Acta Crystallographica D Biol Crystallogr, 61:920, 2005 : PubMed

            

    Title: Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution
    Yang H, Carr PD, McLoughlin SY, Liu JW, Horne I, Qiu X, Jeffries CM, Russell RJ, Oakeshott JG, Ollis DL
    Ref: Protein Engineering, 16:135, 2003 : PubMed

            

    Title: Expression, purification and preliminary crystallographic studies of a hyperthermophilic esterase from Archaeoglobus fulgidus
    Liu JW, Verger D, Carr PD, Yang H, Ollis DL
    Ref: Acta Crystallographica D Biol Crystallogr, 56:900, 2000 : PubMed

            

    Title: Structure of the C123S mutant of dienelactone hydrolase (DLH) bound with the PMS moiety of the protease inhibitor phenylmethylsulfonyl fluoride (PMSF)
    Robinson A, Edwards KJ, Carr PD, Barton JD, Ewart GD, Ollis DL
    Ref: Acta Crystallographica D Biol Crystallogr, 56:1376, 2000 : PubMed

            


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