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Title : Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2\/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence - Dhanya_2014_J.Med.Chem_57_4154 |
Author(s) : Dhanya RP , Sheffler DJ , Dahl R , Davis M , Lee PS , Yang L , Nickols HH , Cho HP , Smith LH , D'Souza MS , Conn PJ , Der-Avakian A , Markou A , Cosford ND |
Ref : Journal of Medicinal Chemistry , 57 :4154 , 2014 |
Abstract : Dhanya_2014_J.Med.Chem_57_4154 |
ESTHER : Dhanya_2014_J.Med.Chem_57_4154 |
PubMedSearch : Dhanya_2014_J.Med.Chem_57_4154 |
PubMedID: 24735492 |
Title : Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models - Digby_2012_J.Neurosci_32_8532 |
Author(s) : Digby GJ , Noetzel MJ , Bubser M , Utley TJ , Walker AG , Byun NE , LeBois EP , Xiang Z , Sheffler DJ , Cho HP , Davis AA , Nemirovsky NE , Mennenga SE , Camp BW , Bimonte-Nelson HA , Bode J , Italiano K , Morrison R , Daniels JS , Niswender CM , Olive MF , Lindsley CW , Jones CK , Conn PJ |
Ref : Journal of Neuroscience , 32 :8532 , 2012 |
Abstract : Digby_2012_J.Neurosci_32_8532 |
ESTHER : Digby_2012_J.Neurosci_32_8532 |
PubMedSearch : Digby_2012_J.Neurosci_32_8532 |
PubMedID: 22723693 |
Title : Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): the development of ML169, an MLPCN probe - Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
Author(s) : Reid PR , Bridges TM , Sheffler DJ , Cho HP , Lewis LM , Days E , Daniels JS , Jones CK , Niswender CM , Weaver CD , Conn PJ , Lindsley CW , Wood MR |
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2697 , 2011 |
Abstract : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
ESTHER : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
PubMedSearch : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
PubMedID: 21194936 |