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Author Report for: Colletier JP

Contact information:

Colletier Jacques-Philippe
Institut de Biologie Structurale UMR 5075; 41 rue Jules Horowitz; 38027 Grenoble
Phone : +33438789573
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Send E-Mail to Colletier Jacques-Philippe

    Title: Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice
    Viayna E, Coquelle N, Cieslikiewicz-Bouet M, Cisternas P, Oliva CA, Sanchez-Lopez E, Ettcheto M, Bartolini M, De Simone A and Munoz-Torrero D <16 more author(s)>
    Ref: Journal of Medicinal Chemistry, 64:812, 2021 : PubMed


    Title: Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor
    Catto M, Pisani L, De la Mora E, Belviso BD, Mangiatordi GF, Pinto A, Palma A, Denora N, Caliandro R and Altomare CD <3 more author(s)>
    Ref: ACS Med Chem Lett, 11:869, 2020 : PubMed


    Title: Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes
    Pajk S, Knez D, Kosak U, Zorovic M, Brazzolotto X, Coquelle N, Nachon F, Colletier JP, Zivin M and Gobec S <1 more author(s)>
    Ref: J Enzyme Inhib Med Chem, 35:498, 2020 : PubMed


    Title: Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3
    Oukoloff K, Coquelle N, Bartolini M, Naldi M, Le Guevel R, Bach S, Josselin B, Ruchaud S, Catto M and Renard PY <9 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 168:58, 2019 : PubMed


    Title: Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis
    Galdeano C, Coquelle N, Cieslikiewicz-Bouet M, Bartolini M, Perez B, Clos MV, Silman I, Jean L, Colletier JP and Munoz-Torrero D <1 more author(s)>
    Ref: Molecules, 23:, 2018 : PubMed


    Title: Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities
    Knez D, Coquelle N, Pislar A, Zakelj S, Jukic M, Sova M, Mravljak J, Nachon F, Brazzolotto X and Gobec S <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 156:598, 2018 : PubMed


    Title: The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity
    Kosak U, Brus B, Knez D, Zakelj S, Trontelj J, Pislar A, Sink R, Jukic M, Zivin M and Gobec S <8 more author(s)>
    Ref: Journal of Medicinal Chemistry, 61:119, 2018 : PubMed


    Title: N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents
    Kosak U, Knez D, Coquelle N, Brus B, Pislar A, Nachon F, Brazzolotto X, Kos J, Colletier JP, Gobec S
    Ref: Bioorganic & Medicinal Chemistry, 25:633, 2017 : PubMed


    Title: Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP
    Colletier JP, Sliwa M, Gallat FX, Sugahara M, Guillon V, Schiro G, Coquelle N, Woodhouse J, Roux L and Weik M <15 more author(s)>
    Ref: J Phys Chem Lett, 7:882, 2016 : PubMed


    Title: Development of an in-vivo active reversible butyrylcholinesterase inhibitor
    Kosak U, Brus B, Knez D, Sink R, Zakelj S, Trontelj J, Pislar A, Slenc J, Gobec M and Gobec S <15 more author(s)>
    Ref: Sci Rep, 6:39495, 2016 : PubMed


    Title: Poster: Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of alpha7 nicotinic acetylcholine receptor
    Araoz R, Bouet m, Bartolini M, Coquelle N, Colletier JP, Servent D, Molgo J, Jean L, Renard PY
    Ref: Biochemical Pharmacology, 97:621, 2015 : PubMed


    Title: Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents
    Knez D, Brus B, Coquelle N, Sosic I, Sink R, Brazzolotto X, Mravljak J, Colletier JP, Gobec S
    Ref: Bioorganic & Medicinal Chemistry, 23:4442, 2015 : PubMed


    Title: Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor
    Brus B, Kosak U, Turk S, Pislar A, Coquelle N, Kos J, Stojan J, Colletier JP, Gobec S
    Ref: Journal of Medicinal Chemistry, 57:8167, 2014 : PubMed


    Title: Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase
    Kliachyna M, Santoni G, Nussbaum V, Renou J, Sanson B, Colletier JP, Arboleas M, Loiodice M, Weik M and Baati R <3 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 78C:455, 2014 : PubMed


    Title: Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry
    Carletti E, Colletier JP, Schopfer LM, Santoni G, Masson P, Lockridge O, Nachon F, Weik M
    Ref: Chemical Research in Toxicology, 26:280, 2013 : PubMed


    Title: Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography
    Ronco C, Carletti E, Colletier JP, Weik M, Nachon F, Jean L, Renard PY
    Ref: ChemMedChem, 7:400, 2012 : PubMed


    Title: Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis
    Carletti E, Schopfer LM, Colletier JP, Froment MT, Nachon F, Weik M, Lockridge O, Masson P
    Ref: Chemical Research in Toxicology, 24:797, 2011 : PubMed


    Title: Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations
    Sanson B, Colletier JP, Xu Y, Lang PT, Jiang H, Silman I, Sussman JL, Weik M
    Ref: Protein Science, 20:1114, 2011 : PubMed


    Title: Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation
    Carletti E, Colletier JP, Dupeux F, Trovaslet M, Masson P, Nachon F
    Ref: Journal of Medicinal Chemistry, 53:4002, 2010 : PubMed


    Title: Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase
    Xu Y, Colletier JP, Weik M, Qin G, Jiang H, Silman I, Sussman JL
    Ref: Biophysical Journal, 99:4003, 2010 : PubMed


    Title: Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime
    Sanson B, Nachon F, Colletier JP, Froment MT, Toker L, Greenblatt HM, Sussman JL, Ashani Y, Masson P and Weik M <1 more author(s)>
    Ref: Journal of Medicinal Chemistry, 52:7593, 2009 : PubMed


    Title: Shoot-and-Trap: use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography
    Colletier JP, Bourgeois D, Sanson B, Fournier D, Sussman JL, Silman I, Weik M
    Ref: Proc Natl Acad Sci U S A, 105:11742, 2008 : PubMed


    Title: Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design
    Xu Y, Colletier JP, Jiang H, Silman I, Sussman JL, Weik M
    Ref: Protein Science, 17:601, 2008 : PubMed


    Title: Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics
    Xu Y, Colletier JP, Weik M, Jiang H, Moult J, Silman I, Sussman JL
    Ref: Biophysical Journal, 95:2500, 2008 : PubMed


    Title: Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography
    Colletier JP, Royant A, Specht A, Sanson B, Nachon F, Masson P, Zaccai G, Sussman JL, Goeldner M and Weik M <2 more author(s)>
    Ref: Acta Crystallographica D Biol Crystallogr, 63:1115, 2007 : PubMed


    Title: [Exploring the conformational energy landscape of acetylcholinesterase by kinetic crystallography]
    Colletier JP, Weik M
    Ref: Ann Pharm Fr, 65:108, 2007 : PubMed


    Title: Mechanisms of cholinesterase inhibition by inorganic mercury
    Frasco MF, Colletier JP, Weik M, Carvalho F, Guilhermino L, Stojan J, Fournier D
    Ref: Febs J, 274:1849, 2007 : PubMed


    Title: Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor
    Colletier JP, Sanson B, Nachon F, Gabellieri E, Fattorusso C, Campiani G, Weik M
    Ref: Journal of the American Chemical Society, 128:4526, 2006 : PubMed


    Title: Structural insights into substrate traffic and inhibition in acetylcholinesterase
    Colletier JP, Fournier D, Greenblatt HM, Stojan J, Sussman JL, Zaccai G, Silman I, Weik M
    Ref: EMBO Journal, 25:2746, 2006 : PubMed


    Title: Encapsulation of enzymes in liposomes: high encapsulation efficiency and control of substrate permeability
    Chaize B, Colletier JP, Winterhalter M, Fournier D
    Ref: Artif Cells Blood Substit Immobil Biotechnol, 32:67, 2004 : PubMed


    Title: Poster (74) Structural studies on torpedo californica acetylcholinesterase in complex with a substrate analogue
    Colletier JP, Fournier D, Greenblatt HM, Sussman JL, Zaccai G, Silman I, Weik M
    Ref: In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects, (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina:359, 2004 : PubMed


    Title: Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate
    Stojan J, Brochier L, Alies C, Colletier JP, Fournier D
    Ref: European Journal of Biochemistry, 271:1364, 2004 : PubMed


    Title: Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer
    Colletier JP, Chaize B, Winterhalter M, Fournier D
    Ref: BMC Biotechnol, 2:9, 2002 : PubMed


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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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