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| Title : Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors - Briggs_2009_Br.J.Pharmacol_158_1486 |
| Author(s) : Briggs CA , Gronlien JH , Curzon P , Timmermann DB , Ween H , Thorin-Hagene K , Kerr P , Anderson DJ , Malysz J , Dyhring T , Olsen GM , Peters D , Bunnelle WH , Gopalakrishnan M |
| Ref : British Journal of Pharmacology , 158 :1486 , 2009 |
| Abstract : Briggs_2009_Br.J.Pharmacol_158_1486 |
| ESTHER : Briggs_2009_Br.J.Pharmacol_158_1486 |
| PubMedSearch : Briggs_2009_Br.J.Pharmacol_158_1486 |
| PubMedID: 19845675 |
| Title : Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties - Tietje_2008_CNS.Neurosci.Ther_14_65 |
| Author(s) : Tietje KR , Anderson DJ , Bitner RS , Blomme EA , Brackemeyer PJ , Briggs CA , Browman KE , Bury D , Curzon P , Drescher KU , Frost JM , Fryer RM , Fox GB , Gronlien JH , Hakerud M , Gubbins EJ , Halm S , Harris R , Helfrich RJ , Kohlhaas KL , Law D , Malysz J , Marsh KC , Martin RL , Meyer MD , Molesky AL , Nikkel AL , Otte S , Pan L , Puttfarcken PS , Radek RJ , Robb HM , Spies E , Thorin-Hagene K , Waring JF , Ween H , Xu H , Gopalakrishnan M , Bunnelle WH |
| Ref : CNS Neurosci Ther , 14 :65 , 2008 |
| Abstract : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| ESTHER : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedSearch : Tietje_2008_CNS.Neurosci.Ther_14_65 |
| PubMedID: 18482100 |
| Title : A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models - Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| Author(s) : Ji J , Bunnelle WH , Anderson DJ , Faltynek C , Dyhring T , Ahring PK , Rueter LE , Curzon P , Buckley MJ , Marsh KC , Kempf-Grote A , Meyer MD |
| Ref : Biochemical Pharmacology , 74 :1253 , 2007 |
| Abstract : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| ESTHER : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| PubMedSearch : Ji_2007_Biochem.Pharmacol_74(8)_1253 |
| PubMedID: 17854775 |
| Title : Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1\/2 and CREB phosphorylation pathways - Bitner_2007_J.Neurosci_27_10578 |
| Author(s) : Bitner RS , Bunnelle WH , Anderson DJ , Briggs CA , Buccafusco JJ , Curzon P , Decker MW , Frost JM , Gronlien JH , Gubbins E , Li J , Malysz J , Markosyan S , Marsh K , Meyer MD , Nikkel AL , Radek RJ , Robb HM , Timmermann DB , Sullivan JP , Gopalakrishnan M |
| Ref : Journal of Neuroscience , 27 :10578 , 2007 |
| Abstract : Bitner_2007_J.Neurosci_27_10578 |
| ESTHER : Bitner_2007_J.Neurosci_27_10578 |
| PubMedSearch : Bitner_2007_J.Neurosci_27_10578 |
| PubMedID: 17898229 |
| Title : A-85380: a pharmacological probe for the preclinical and clinical investigation of the alphabeta neuronal nicotinic acetylcholine receptor - Rueter_2006_CNS.Drug.Rev_12_100 |
| Author(s) : Rueter LE , Donnelly-Roberts D , Curzon P , Briggs CA , Anderson DJ , Bitner RS |
| Ref : CNS Drug Rev , 12 :100 , 2006 |
| Abstract : Rueter_2006_CNS.Drug.Rev_12_100 |
| ESTHER : Rueter_2006_CNS.Drug.Rev_12_100 |
| PubMedSearch : Rueter_2006_CNS.Drug.Rev_12_100 |
| PubMedID: 16958984 |
| Title : Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment - Curzon_2006_Neurosci.Lett_410_15 |
| Author(s) : Curzon P , Anderson DJ , Nikkel AL , Fox GB , Gopalakrishnan M , Decker MW , Bitner RS |
| Ref : Neuroscience Letters , 410 :15 , 2006 |
| Abstract : Curzon_2006_Neurosci.Lett_410_15 |
| ESTHER : Curzon_2006_Neurosci.Lett_410_15 |
| PubMedSearch : Curzon_2006_Neurosci.Lett_410_15 |
| PubMedID: 17055644 |
| Title : In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide - Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| Author(s) : Adams MR , Nikkel AL , Donnelly-Roberts D , Watt AT , Johnston JF , Cowsert LM , Butler M , Kroeger PE , Frost L , Curzon P , Decker MW , Bitner RS |
| Ref : Brain Research Mol Brain Res , 129 :67 , 2004 |
| Abstract : Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| ESTHER : Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| PubMedSearch : Adams_2004_Brain.Res.Mol.Brain.Res_129_67 |
| PubMedID: 15469883 |
| Title : Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat - Bitner_2000_Brain.Res_871_66 |
| Author(s) : Bitner RS , Nikkel AL , Curzon P , Donnelly-Roberts D , Puttfarcken PS , Namovic M , Jacobs IC , Meyer MD , Decker MW |
| Ref : Brain Research , 871 :66 , 2000 |
| Abstract : Bitner_2000_Brain.Res_871_66 |
| ESTHER : Bitner_2000_Brain.Res_871_66 |
| PubMedSearch : Bitner_2000_Brain.Res_871_66 |
| PubMedID: 10882784 |
| Title : Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors - Bannon_1998_Science_279_77 |
| Author(s) : Bannon AW , Decker MW , Holladay MW , Curzon P , Donnelly-Roberts D , Puttfarcken PS , Bitner RS , Diaz A , Dickenson AH , Porsolt RD , Williams M , Arneric SP |
| Ref : Science , 279 :77 , 1998 |
| Abstract : Bannon_1998_Science_279_77 |
| ESTHER : Bannon_1998_Science_279_77 |
| PubMedSearch : Bannon_1998_Science_279_77 |
| PubMedID: 9417028 |
| Title : The role of neuronal nicotinic acetylcholine receptors in antinociception: effects of ABT-594 - Decker_1998_J.Physiol.Paris_92_221 |
| Author(s) : Decker MW , Curzon P , Holladay MW , Nikkel AL , Bitner RS , Bannon AW , Donnelly-Roberts D , Puttfarcken PS , Kuntzweiler TA , Briggs CA , Williams M , Arneric SP |
| Ref : Journal de Physiologie (Paris) , 92 :221 , 1998 |
| Abstract : Decker_1998_J.Physiol.Paris_92_221 |
| ESTHER : Decker_1998_J.Physiol.Paris_92_221 |
| PubMedSearch : Decker_1998_J.Physiol.Paris_92_221 |
| PubMedID: 9789812 |
| Title : ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization - Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| Author(s) : Bannon AW , Decker MW , Curzon P , Buckley MJ , Kim DJ , Radek RJ , Lynch JK , Wasicak JT , Lin NH , Arnold WH , Holladay MW , Williams M , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 285 :787 , 1998 |
| Abstract : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| ESTHER : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| PubMedSearch : Bannon_1998_J.Pharmacol.Exp.Ther_285_787 |
| PubMedID: 9580627 |
| Title : ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys - Decker_1997_J.Pharmacol.Exp.Ther_283_247 |
| Author(s) : Decker MW , Bannon AW , Curzon P , Gunther KL , Brioni JD , Holladay MW , Lin NH , Li Y , Daanen JF , Buccafusco JJ , Prendergast MA , Jackson WJ , Arneric SP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :247 , 1997 |
| Abstract : Decker_1997_J.Pharmacol.Exp.Ther_283_247 |
| ESTHER : Decker_1997_J.Pharmacol.Exp.Ther_283_247 |
| PubMedSearch : Decker_1997_J.Pharmacol.Exp.Ther_283_247 |
| PubMedID: 9336330 |