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| Title : Synthesis, biological evaluation, and computational studies of N-benzyl pyridinium-curcumin derivatives as potent AChE inhibitors with antioxidant activity - Al-Rifai_2023_J.Enzyme.Inhib.Med.Chem_38_2281264 |
| Author(s) : Al-Rifai NM , Al-Khalileh NM , Zahra JA , El-Barghouthi MI , Darras FH |
| Ref : J Enzyme Inhib Med Chem , 38 :2281264 , 2023 |
| Abstract : Al-Rifai_2023_J.Enzyme.Inhib.Med.Chem_38_2281264 |
| ESTHER : Al-Rifai_2023_J.Enzyme.Inhib.Med.Chem_38_2281264 |
| PubMedSearch : Al-Rifai_2023_J.Enzyme.Inhib.Med.Chem_38_2281264 |
| PubMedID: 37985494 |
| Title : On the use of the experimentally determined enzyme inhibition constant as a measure of absolute binding affinity - Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| Author(s) : Darras FH , Pang YP |
| Ref : Biochemical & Biophysical Research Communications , 489 :451 , 2017 |
| Abstract : Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| ESTHER : Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| PubMedSearch : Darras_2017_Biochem.Biophys.Res.Commun_489_451 |
| PubMedID: 28571743 |
| Title : The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats - Sadek_2016_Physiol.Behav_165_383 |
| Author(s) : Sadek B , Khan N , Darras FH , Pockes S , Decker M |
| Ref : Physiol Behav , 165 :383 , 2016 |
| Abstract : Sadek_2016_Physiol.Behav_165_383 |
| ESTHER : Sadek_2016_Physiol.Behav_165_383 |
| PubMedSearch : Sadek_2016_Physiol.Behav_165_383 |
| PubMedID: 27568232 |
| Title : The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats - Khan_2015_Behav.Brain.Res_297_155 |
| Author(s) : Khan N , Saad A , Nurulain SM , Darras FH , Decker M , Sadek B |
| Ref : Behavioural Brain Research , 297 :155 , 2015 |
| Abstract : Khan_2015_Behav.Brain.Res_297_155 |
| ESTHER : Khan_2015_Behav.Brain.Res_297_155 |
| PubMedSearch : Khan_2015_Behav.Brain.Res_297_155 |
| PubMedID: 26467607 |
| Title : Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine - Huang_2014_Eur.J.Med.Chem_81C_15 |
| Author(s) : Huang G , Kling B , Darras FH , Heilmann J , Decker M |
| Ref : Eur Journal of Medicinal Chemistry , 81C :15 , 2014 |
| Abstract : Huang_2014_Eur.J.Med.Chem_81C_15 |
| ESTHER : Huang_2014_Eur.J.Med.Chem_81C_15 |
| PubMedSearch : Huang_2014_Eur.J.Med.Chem_81C_15 |
| PubMedID: 24819955 |
| Title : Synthesis, Biological Evaluation, and Computational Studies of Tri- and Tetracyclic Nitrogen-Bridgehead Compounds as Potent Dual-Acting AChE Inhibitors and hH3 Receptor Antagonists - Darras_2014_ACS.Chem.Neurosci_5_225 |
| Author(s) : Darras FH , Pockes S , Huang G , Wehle S , Strasser A , Wittmann HJ , Nimczick M , Sotriffer CA , Decker M |
| Ref : ACS Chem Neurosci , 5 :225 , 2014 |
| Abstract : Darras_2014_ACS.Chem.Neurosci_5_225 |
| ESTHER : Darras_2014_ACS.Chem.Neurosci_5_225 |
| PubMedSearch : Darras_2014_ACS.Chem.Neurosci_5_225 |
| PubMedID: 24422467 |
| Title : Cyclic acyl guanidines bearing carbamate moieties allow potent and dirigible cholinesterase inhibition of either acetyl- or butyrylcholinesterase - Darras_2014_Bioorg.Med.Chem_22_5020 |
| Author(s) : Darras FH , Kling B , Sawatzky E , Heilmann J , Decker M |
| Ref : Bioorganic & Medicinal Chemistry , 22 :5020 , 2014 |
| Abstract : Darras_2014_Bioorg.Med.Chem_22_5020 |
| ESTHER : Darras_2014_Bioorg.Med.Chem_22_5020 |
| PubMedSearch : Darras_2014_Bioorg.Med.Chem_22_5020 |
| PubMedID: 25059502 |
| Title : Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with 'inverted' binding mode - Darras_2014_Bioorg.Med.Chem_22_4867 |
| Author(s) : Darras FH , Wehle S , Huang G , Sotriffer CA , Decker M |
| Ref : Bioorganic & Medicinal Chemistry , 22 :4867 , 2014 |
| Abstract : Darras_2014_Bioorg.Med.Chem_22_4867 |
| ESTHER : Darras_2014_Bioorg.Med.Chem_22_4867 |
| PubMedSearch : Darras_2014_Bioorg.Med.Chem_22_4867 |
| PubMedID: 25047936 |
| Title : Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer - Darras_2012_ACS.Med.Chem.Lett_3_914 |
| Author(s) : Darras FH , Kling B , Heilmann J , Decker M |
| Ref : ACS Med Chem Lett , 3 :914 , 2012 |
| Abstract : Darras_2012_ACS.Med.Chem.Lett_3_914 |
| ESTHER : Darras_2012_ACS.Med.Chem.Lett_3_914 |
| PubMedSearch : Darras_2012_ACS.Med.Chem.Lett_3_914 |
| PubMedID: 24900407 |