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| Title : Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors - Maspero_2020_Bioorg.Chem_96_103633 |
| Author(s) : Maspero M , Volpato D , Cirillo D , Yuan Chen N , Messerer R , Sotriffer C , De Amici M , Holzgrabe U , Dallanoce C |
| Ref : Bioorg Chem , 96 :103633 , 2020 |
| Abstract : Maspero_2020_Bioorg.Chem_96_103633 |
| ESTHER : Maspero_2020_Bioorg.Chem_96_103633 |
| PubMedSearch : Maspero_2020_Bioorg.Chem_96_103633 |
| PubMedID: 32032848 |
| Title : Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the alpha3beta4 nicotinic acetylcholine receptor subtype - Matera_2016_Eur.J.Med.Chem_108_392 |
| Author(s) : Matera C , Quadri M , Sciaccaluga M , Pome DY , Fasoli F , De Amici M , Fucile S , Gotti C , Dallanoce C , Grazioso G |
| Ref : Eur Journal of Medicinal Chemistry , 108 :392 , 2016 |
| Abstract : Matera_2016_Eur.J.Med.Chem_108_392 |
| ESTHER : Matera_2016_Eur.J.Med.Chem_108_392 |
| PubMedSearch : Matera_2016_Eur.J.Med.Chem_108_392 |
| PubMedID: 26706350 |
| Title : Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity - Matera_2014_Eur.J.Med.Chem_75C_222 |
| Author(s) : Matera C , Flammini L , Quadri M , Vivo V , Ballabeni V , Holzgrabe U , Mohr K , De Amici M , Barocelli E , Bertoni S , Dallanoce C |
| Ref : Eur Journal of Medicinal Chemistry , 75C :222 , 2014 |
| Abstract : Matera_2014_Eur.J.Med.Chem_75C_222 |
| ESTHER : Matera_2014_Eur.J.Med.Chem_75C_222 |
| PubMedSearch : Matera_2014_Eur.J.Med.Chem_75C_222 |
| PubMedID: 24534538 |
| Title : Involvement of alpha7 nAChR subtype in rat oxaliplatin-induced neuropathy: Effects of selective activation - Di Cesare_2014_Neuropharmacol_79_37 |
| Author(s) : Di Cesare Mannelli L , Pacini A , Matera C , Zanardelli M , Mello T , De Amici M , Dallanoce C , Ghelardini C |
| Ref : Neuropharmacology , 79 :37 , 2014 |
| Abstract : Di Cesare_2014_Neuropharmacol_79_37 |
| ESTHER : Di Cesare_2014_Neuropharmacol_79_37 |
| PubMedSearch : Di Cesare_2014_Neuropharmacol_79_37 |
| PubMedID: 24225197 |
| Title : Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor - Schrage_2013_Br.J.Pharmacol_169_357 |
| Author(s) : Schrage R , Seemann WK , Klockner J , Dallanoce C , Racke K , Kostenis E , De Amici M , Holzgrabe U , Mohr K |
| Ref : British Journal of Pharmacology , 169 :357 , 2013 |
| Abstract : Schrage_2013_Br.J.Pharmacol_169_357 |
| ESTHER : Schrage_2013_Br.J.Pharmacol_169_357 |
| PubMedSearch : Schrage_2013_Br.J.Pharmacol_169_357 |
| PubMedID: 23062057 |
| Title : The enantiomers of epiboxidine and of two related analogs: synthesis and estimation of their binding affinity at alpha4beta2 and alpha7 neuronal nicotinic acetylcholine receptors - Dallanoce_2012_Chirality_24_543 |
| Author(s) : Dallanoce C , Matera C , De Amici M , Rizzi L , Pucci L , Gotti C , Clementi F , De Micheli C |
| Ref : Chirality , 24 :543 , 2012 |
| Abstract : Dallanoce_2012_Chirality_24_543 |
| ESTHER : Dallanoce_2012_Chirality_24_543 |
| PubMedSearch : Dallanoce_2012_Chirality_24_543 |
| PubMedID: 22566097 |
| Title : The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling - Bock_2012_Nat.Commun_3_1044 |
| Author(s) : Bock A , Merten N , Schrage R , Dallanoce C , Batz J , Klockner J , Schmitz J , Matera C , Simon K , Kebig A , Peters L , Muller A , Schrobang-Ley J , Trankle C , Hoffmann C , De Amici M , Holzgrabe U , Kostenis E , Mohr K |
| Ref : Nat Commun , 3 :1044 , 2012 |
| Abstract : Bock_2012_Nat.Commun_3_1044 |
| ESTHER : Bock_2012_Nat.Commun_3_1044 |
| PubMedSearch : Bock_2012_Nat.Commun_3_1044 |
| PubMedID: 22948826 |
| Title : Engineering of alpha-conotoxin MII-derived peptides with increased selectivity for native alpha6beta2* nicotinic acetylcholine receptors - Pucci_2011_FASEB.J_25_3775 |
| Author(s) : Pucci L , Grazioso G , Dallanoce C , Rizzi L , De Micheli C , Clementi F , Bertrand S , Bertrand D , Longhi R , De Amici M , Gotti C |
| Ref : FASEB Journal , 25 :3775 , 2011 |
| Abstract : Pucci_2011_FASEB.J_25_3775 |
| ESTHER : Pucci_2011_FASEB.J_25_3775 |
| PubMedSearch : Pucci_2011_FASEB.J_25_3775 |
| PubMedID: 21778325 |
| Title : New spirocyclic Delta(2)-isoxazoline derivatives related to selective agonists of alpha7 neuronal nicotinic acetylcholine receptors - Dallanoce_2011_Eur.J.Med.Chem_46_5790 |
| Author(s) : Dallanoce C , Frigerio F , Grazioso G , Matera C , Visconti GL , De Amici M , Pucci L , Pistillo F , Fucile S , Gotti C , Clementi F , De Micheli C |
| Ref : Eur Journal of Medicinal Chemistry , 46 :5790 , 2011 |
| Abstract : Dallanoce_2011_Eur.J.Med.Chem_46_5790 |
| ESTHER : Dallanoce_2011_Eur.J.Med.Chem_46_5790 |
| PubMedSearch : Dallanoce_2011_Eur.J.Med.Chem_46_5790 |
| PubMedID: 22014558 |
| Title : Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2-isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors - Dallanoce_2011_ChemMedChem_6_889 |
| Author(s) : Dallanoce C , Magrone P , Matera C , Frigerio F , Grazioso G , De Amici M , Fucile S , Piccari V , Frydenvang K , Pucci L , Gotti C , Clementi F , De Micheli C |
| Ref : ChemMedChem , 6 :889 , 2011 |
| Abstract : Dallanoce_2011_ChemMedChem_6_889 |
| ESTHER : Dallanoce_2011_ChemMedChem_6_889 |
| PubMedSearch : Dallanoce_2011_ChemMedChem_6_889 |
| PubMedID: 21365765 |
| Title : Rational design of dualsteric GPCR ligands: quests and promise - Mohr_2010_Br.J.Pharmacol_159_997 |
| Author(s) : Mohr K , Trankle C , Kostenis E , Barocelli E , De Amici M , Holzgrabe U |
| Ref : British Journal of Pharmacology , 159 :997 , 2010 |
| Abstract : Mohr_2010_Br.J.Pharmacol_159_997 |
| ESTHER : Mohr_2010_Br.J.Pharmacol_159_997 |
| PubMedSearch : Mohr_2010_Br.J.Pharmacol_159_997 |
| PubMedID: 20136835 |
| Title : Synthesis of novel chiral Delta2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes - Dallanoce_2010_Eur.J.Med.Chem_45_5594 |
| Author(s) : Dallanoce C , Magrone P , Matera C , Lo Presti L , De Amici M , Riganti L , Clementi F , Gotti C , De Micheli C |
| Ref : Eur Journal of Medicinal Chemistry , 45 :5594 , 2010 |
| Abstract : Dallanoce_2010_Eur.J.Med.Chem_45_5594 |
| ESTHER : Dallanoce_2010_Eur.J.Med.Chem_45_5594 |
| PubMedSearch : Dallanoce_2010_Eur.J.Med.Chem_45_5594 |
| PubMedID: 20932609 |
| Title : Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes - Dallanoce_2010_Bioorg.Med.Chem_18_4498 |
| Author(s) : Dallanoce C , Frigerio F , Martelli G , Grazioso G , Matera C , Pome DY , Pucci L , Clementi F , Gotti C , De Amici M |
| Ref : Bioorganic & Medicinal Chemistry , 18 :4498 , 2010 |
| Abstract : Dallanoce_2010_Bioorg.Med.Chem_18_4498 |
| ESTHER : Dallanoce_2010_Bioorg.Med.Chem_18_4498 |
| PubMedSearch : Dallanoce_2010_Bioorg.Med.Chem_18_4498 |
| PubMedID: 20478710 |
| Title : Design of novel alpha7-subtype-preferring nicotinic acetylcholine receptor agonists: application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies - Grazioso_2009_Bioorg.Med.Chem.Lett_19_6353 |
| Author(s) : Grazioso G , Pome DY , Matera C , Frigerio F , Pucci L , Gotti C , Dallanoce C , De Amici M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :6353 , 2009 |
| Abstract : Grazioso_2009_Bioorg.Med.Chem.Lett_19_6353 |
| ESTHER : Grazioso_2009_Bioorg.Med.Chem.Lett_19_6353 |
| PubMedSearch : Grazioso_2009_Bioorg.Med.Chem.Lett_19_6353 |
| PubMedID: 19804970 |
| Title : Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity - Antony_2009_FASEB.J_23_442 |
| Author(s) : Antony J , Kellershohn K , Mohr-Andra M , Kebig A , Prilla S , Muth M , Heller E , Disingrini T , Dallanoce C , Bertoni S , Schrobang J , Trankle C , Kostenis E , Christopoulos A , Holtje HD , Barocelli E , De Amici M , Holzgrabe U , Mohr K |
| Ref : FASEB Journal , 23 :442 , 2009 |
| Abstract : Antony_2009_FASEB.J_23_442 |
| ESTHER : Antony_2009_FASEB.J_23_442 |
| PubMedSearch : Antony_2009_FASEB.J_23_442 |
| PubMedID: 18842964 |
| Title : New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations - Dallanoce_2009_Chem.Biodivers_6_244 |
| Author(s) : Dallanoce C , Magrone P , Bazza P , Grazioso G , Rizzi L , Riganti L , Gotti C , Clementi F , Frydenvang K , De Amici M |
| Ref : Chem Biodivers , 6 :244 , 2009 |
| Abstract : Dallanoce_2009_Chem.Biodivers_6_244 |
| ESTHER : Dallanoce_2009_Chem.Biodivers_6_244 |
| PubMedSearch : Dallanoce_2009_Chem.Biodivers_6_244 |
| PubMedID: 19235154 |
| Title : Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes - Rizzi_2008_Bioorg.Med.Chem.Lett_18_4651 |
| Author(s) : Rizzi L , Dallanoce C , Matera C , Magrone P , Pucci L , Gotti C , Clementi F , De Amici M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :4651 , 2008 |
| Abstract : Rizzi_2008_Bioorg.Med.Chem.Lett_18_4651 |
| ESTHER : Rizzi_2008_Bioorg.Med.Chem.Lett_18_4651 |
| PubMedSearch : Rizzi_2008_Bioorg.Med.Chem.Lett_18_4651 |
| PubMedID: 18644719 |
| Title : Allosteric modulators and selective agonists of muscarinic receptors - Holzgrabe_2006_J.Mol.Neurosci_30_165 |
| Author(s) : Holzgrabe U , De Amici M , Mohr K |
| Ref : Journal of Molecular Neuroscience , 30 :165 , 2006 |
| Abstract : Holzgrabe_2006_J.Mol.Neurosci_30_165 |
| ESTHER : Holzgrabe_2006_J.Mol.Neurosci_30_165 |
| PubMedSearch : Holzgrabe_2006_J.Mol.Neurosci_30_165 |
| PubMedID: 17192667 |
| Title : Synthesis and pharmacological characterization of new chiral derivatives of muscarine and allo-muscarine - De Amici_2000_Farmaco_55_535 |
| Author(s) : De Amici M , Dallanoce C , Angeli P , Marucci G , Cantalamessa F , De Micheli C |
| Ref : Farmaco , 55 :535 , 2000 |
| Abstract : De Amici_2000_Farmaco_55_535 |
| ESTHER : De Amici_2000_Farmaco_55_535 |
| PubMedSearch : De Amici_2000_Farmaco_55_535 |
| PubMedID: 11132731 |
| Title : Poster: Synthesis and pharmacological investigation of chiral stereoisomeric difluoromuscarines - |
| Author(s) : De Micheli C , De Amici M , Marucci G , Paparelli F |
| Ref : Life Sciences , 56(11-12) :1012 , 1995 |
| PubMedID: |
| Title : Synthesis and muscarinic activity of the chiral forms of methylenemuscarones - De Amici_1993_Farmaco_48_1349 |
| Author(s) : De Amici M , De Micheli C , Gianferrara T , Grana E , Dondi G , Ladinsky H , Schiavi G |
| Ref : Farmaco , 48 :1349 , 1993 |
| Abstract : De Amici_1993_Farmaco_48_1349 |
| ESTHER : De Amici_1993_Farmaco_48_1349 |
| PubMedSearch : De Amici_1993_Farmaco_48_1349 |
| PubMedID: 8117378 |
| Title : Synthesis and pharmacological investigation of the enantiomers of muscarone and allomuscarone - De Amici_1992_J.Med.Chem_35_1915 |
| Author(s) : De Amici M , Dallanoce C , De Micheli C , Grana E , Barbieri A , Ladinsky H , Schiavi G , Zonta F |
| Ref : Journal of Medicinal Chemistry , 35 :1915 , 1992 |
| Abstract : De Amici_1992_J.Med.Chem_35_1915 |
| ESTHER : De Amici_1992_J.Med.Chem_35_1915 |
| PubMedSearch : De Amici_1992_J.Med.Chem_35_1915 |
| PubMedID: 1588567 |
| Title : Synthesis and pharmacological investigation of stereoisomeric muscarines - De Amici_1992_Chirality_4_230 |
| Author(s) : De Amici M , Dallanoce C , De Micheli C , Grana E , Dondi G , Ladinsky H , Schiavi G , Zonta F |
| Ref : Chirality , 4 :230 , 1992 |
| Abstract : De Amici_1992_Chirality_4_230 |
| ESTHER : De Amici_1992_Chirality_4_230 |
| PubMedSearch : De Amici_1992_Chirality_4_230 |
| PubMedID: 1389960 |