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| Title : Active site-directed probes targeting dipeptidyl peptidases 8 and 9 - Espadinha_2024_Eur.J.Med.Chem_270_116389 |
| Author(s) : Espadinha M , De Loose J , Corthaut S , Thys S , Van Rymenant Y , Verhulst E , Benramdane S , Filippi N , Augustyns K , Van Wielendaele P , Pintelon I , De Meester I , Van der Veken P |
| Ref : Eur Journal of Medicinal Chemistry , 270 :116389 , 2024 |
| Abstract : Espadinha_2024_Eur.J.Med.Chem_270_116389 |
| ESTHER : Espadinha_2024_Eur.J.Med.Chem_270_116389 |
| PubMedSearch : Espadinha_2024_Eur.J.Med.Chem_270_116389 |
| PubMedID: 38593588 |
| Title : Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin - Benramdane_2023_J.Med.Chem__ |
| Author(s) : Benramdane S , De Loose J , Filippi N , Espadinha M , Beyens O , Rymenant YV , Dirkx L , Bozdag M , Feijens PB , Augustyns K , Caljon G , De Winter H , De Meester I , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : Benramdane_2023_J.Med.Chem__ |
| ESTHER : Benramdane_2023_J.Med.Chem__ |
| PubMedSearch : Benramdane_2023_J.Med.Chem__ |
| PubMedID: 37721854 |
| Title : Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8\/9-Specific Lead - Benramdane_2022_ChemMedChem__e202200097 |
| Author(s) : Benramdane S , De Loose J , Beyens O , Van Rymenant Y , Vliegen G , Augustyns K , De Winter H , De Meester I , Van der Veken P |
| Ref : ChemMedChem , :e202200097 , 2022 |
| Abstract : Benramdane_2022_ChemMedChem__e202200097 |
| ESTHER : Benramdane_2022_ChemMedChem__e202200097 |
| PubMedSearch : Benramdane_2022_ChemMedChem__e202200097 |
| PubMedID: 35760756 |
| Title : Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA(5m) chelators - Moon_2020_EJNMMI.Radiopharm.Chem_5_19 |
| Author(s) : Moon ES , Elvas F , Vliegen G , De Lombaerde S , Vangestel C , De Bruycker S , Bracke A , Eppard E , Greifenstein L , Klasen B , Kramer V , Staelens S , De Meester I , Van der Veken P , Rosch F |
| Ref : EJNMMI Radiopharm Chem , 5 :19 , 2020 |
| Abstract : Moon_2020_EJNMMI.Radiopharm.Chem_5_19 |
| ESTHER : Moon_2020_EJNMMI.Radiopharm.Chem_5_19 |
| PubMedSearch : Moon_2020_EJNMMI.Radiopharm.Chem_5_19 |
| PubMedID: 32728930 |
| Title : CD26\/DPP4 - a potential biomarker and target for cancer therapy - Enz_2019_Pharmacol.Ther_198_135 |
| Author(s) : Enz N , Vliegen G , De Meester I , Jungraithmayr W |
| Ref : Pharmacol Ther , 198 :135 , 2019 |
| Abstract : Enz_2019_Pharmacol.Ther_198_135 |
| ESTHER : Enz_2019_Pharmacol.Ther_198_135 |
| PubMedSearch : Enz_2019_Pharmacol.Ther_198_135 |
| PubMedID: 30822465 |
| Title : The development and validation of a combined kinetic fluorometric activity assay for fibroblast activation protein alpha and prolyl oligopeptidase in plasma - Bracke_2019_Clin.Chim.Acta_495_154 |
| Author(s) : Bracke A , Van Elzen R , Van der Veken P , Augustyns K , De Meester I , Lambeir AM |
| Ref : Clinica Chimica Acta , 495 :154 , 2019 |
| Abstract : Bracke_2019_Clin.Chim.Acta_495_154 |
| ESTHER : Bracke_2019_Clin.Chim.Acta_495_154 |
| PubMedSearch : Bracke_2019_Clin.Chim.Acta_495_154 |
| PubMedID: 30981844 |
| Gene_locus related to this paper: human-FAP , human-PREP |
| Title : DPP8\/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages - de Vasconcelos_2019_Life.Sci.Alliance_2_ |
| Author(s) : de Vasconcelos NM , Vliegen G , Goncalves A , De Hert E , Martin-Perez R , Van Opdenbosch N , Jallapally A , Geiss-Friedlander R , Lambeir AM , Augustyns K , Van der Veken P , De Meester I , Lamkanfi M |
| Ref : Life Sciences Alliance , 2 : , 2019 |
| Abstract : de Vasconcelos_2019_Life.Sci.Alliance_2_ |
| ESTHER : de Vasconcelos_2019_Life.Sci.Alliance_2_ |
| PubMedSearch : de Vasconcelos_2019_Life.Sci.Alliance_2_ |
| PubMedID: 30718379 |
| Gene_locus related to this paper: human-DPP8 , human-DPP9 |
| Title : The expression of proline-specific enzymes in the human lung - Vliegen_2017_Ann.Transl.Med_5_130 |
| Author(s) : Vliegen G , Raju TK , Adriaensen D , Lambeir AM , De Meester I |
| Ref : Ann Transl Med , 5 :130 , 2017 |
| Abstract : Vliegen_2017_Ann.Transl.Med_5_130 |
| ESTHER : Vliegen_2017_Ann.Transl.Med_5_130 |
| PubMedSearch : Vliegen_2017_Ann.Transl.Med_5_130 |
| PubMedID: 28462210 |
| Title : Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling - Rea_2017_Eur.J.Med.Chem_139_482 |
| Author(s) : Rea D , Van Elzen R , De Winter H , Van Goethem S , Landuyt B , Luyten W , Schoofs L , Van der Veken P , Augustyns K , De Meester I , Fulop V , Lambeir AM |
| Ref : Eur Journal of Medicinal Chemistry , 139 :482 , 2017 |
| Abstract : Rea_2017_Eur.J.Med.Chem_139_482 |
| ESTHER : Rea_2017_Eur.J.Med.Chem_139_482 |
| PubMedSearch : Rea_2017_Eur.J.Med.Chem_139_482 |
| PubMedID: 28826083 |
| Gene_locus related to this paper: porgi-DPP |
| Title : Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme - |
| Author(s) : Kehoe K , Van Elzen R , Verkerk R , Sim Y , Van der Veken P , Lambeir AM , De Meester I |
| Ref : Biochimica & Biophysica Acta , 1864 :1481 , 2016 |
| PubMedID: 27449720 |
| Gene_locus related to this paper: human-PRCP |
| Title : The Dipeptidyl Peptidases 4, 8, and 9 in Mouse Monocytes and Macrophages: DPP8\/9 Inhibition Attenuates M1 Macrophage Activation in Mice - Waumans_2016_Inflammation_39_413 |
| Author(s) : Waumans Y , Vliegen G , Maes L , Rombouts M , Declerck K , Van der Veken P , Vanden Berghe W , De Meyer GRY , Schrijvers D , De Meester I |
| Ref : Inflammation , 39 :413 , 2016 |
| Abstract : Waumans_2016_Inflammation_39_413 |
| ESTHER : Waumans_2016_Inflammation_39_413 |
| PubMedSearch : Waumans_2016_Inflammation_39_413 |
| PubMedID: 26454447 |
| Title : The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis - Waumans_2015_Front.Immunol_6_387 |
| Author(s) : Waumans Y , Baerts L , Kehoe K , Lambeir AM , De Meester I |
| Ref : Front Immunol , 6 :387 , 2015 |
| Abstract : Waumans_2015_Front.Immunol_6_387 |
| ESTHER : Waumans_2015_Front.Immunol_6_387 |
| PubMedSearch : Waumans_2015_Front.Immunol_6_387 |
| PubMedID: 26300881 |
| Title : Prolyl carboxypeptidase activity decline correlates with severity and short-term outcome in acute ischemic stroke - Kehoe_2015_Neurochem.Res_40_81 |
| Author(s) : Kehoe K , Brouns R , Verkerk R , Engelborghs S , De Deyn PP , Hendriks D , De Meester I |
| Ref : Neurochem Res , 40 :81 , 2015 |
| Abstract : Kehoe_2015_Neurochem.Res_40_81 |
| ESTHER : Kehoe_2015_Neurochem.Res_40_81 |
| PubMedSearch : Kehoe_2015_Neurochem.Res_40_81 |
| PubMedID: 25370794 |
| Gene_locus related to this paper: human-PRCP |
| Title : Importance of biofilm formation and dipeptidyl peptidase IV for the pathogenicity of clinical Porphyromonas gingivalis isolates - Clais_2014_Pathog.Dis_70_408 |
| Author(s) : Clais S , Boulet G , Kerstens M , Horemans T , Teughels W , Quirynen M , Lanckacker E , De Meester I , Lambeir AM , Delputte P , Maes L , Cos P |
| Ref : Pathog Dis , 70 :408 , 2014 |
| Abstract : Clais_2014_Pathog.Dis_70_408 |
| ESTHER : Clais_2014_Pathog.Dis_70_408 |
| PubMedSearch : Clais_2014_Pathog.Dis_70_408 |
| PubMedID: 24532232 |
| Title : Left ventricular diastolic dysfunction and myocardial stiffness in diabetic mice is attenuated by inhibition of dipeptidyl peptidase 4 - Hamdani_2014_Cardiovasc.Res_104_423 |
| Author(s) : Hamdani N , Hervent AS , Vandekerckhove L , Matheeussen V , Demolder M , Baerts L , De Meester I , Linke WA , Paulus WJ , De Keulenaer GW |
| Ref : Cardiovascular Research , 104 :423 , 2014 |
| Abstract : Hamdani_2014_Cardiovasc.Res_104_423 |
| ESTHER : Hamdani_2014_Cardiovasc.Res_104_423 |
| PubMedSearch : Hamdani_2014_Cardiovasc.Res_104_423 |
| PubMedID: 25341892 |
| Title : Extended structure-activity relationship and pharmacokinetic investigation of (4-quinolinoyl)glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP) - Jansen_2014_J.Med.Chem_57_3053 |
| Author(s) : Jansen K , Heirbaut L , Verkerk R , Cheng JD , Joossens J , Cos P , Maes L , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 57 :3053 , 2014 |
| Abstract : Jansen_2014_J.Med.Chem_57_3053 |
| ESTHER : Jansen_2014_J.Med.Chem_57_3053 |
| PubMedSearch : Jansen_2014_J.Med.Chem_57_3053 |
| PubMedID: 24617858 |
| Title : Validation of a specific prolylcarboxypeptidase activity assay and its suitability for plasma and serum measurements - Kehoe_2013_Anal.Biochem_443_232 |
| Author(s) : Kehoe K , Verkerk R , Sim Y , Waumans Y , Van der Veken P , Lambeir AM , De Meester I |
| Ref : Analytical Biochemistry , 443 :232 , 2013 |
| Abstract : Kehoe_2013_Anal.Biochem_443_232 |
| ESTHER : Kehoe_2013_Anal.Biochem_443_232 |
| PubMedSearch : Kehoe_2013_Anal.Biochem_443_232 |
| PubMedID: 24036038 |
| Title : Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis - Matheeussen_2013_Basic.Res.Cardiol_108_350 |
| Author(s) : Matheeussen V , Waumans Y , Martinet W , Van Goethem S , Van der Veken P , Scharpe S , Augustyns K , De Meyer GR , De Meester I |
| Ref : Basic Res Cardiol , 108 :350 , 2013 |
| Abstract : Matheeussen_2013_Basic.Res.Cardiol_108_350 |
| ESTHER : Matheeussen_2013_Basic.Res.Cardiol_108_350 |
| PubMedSearch : Matheeussen_2013_Basic.Res.Cardiol_108_350 |
| PubMedID: 23608773 |
| Title : Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold - Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| Author(s) : Jansen K , Heirbaut L , Cheng JD , Joossens J , Ryabtsova O , Cos P , Maes L , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : ACS Med Chem Lett , 4 :491 , 2013 |
| Abstract : Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| ESTHER : Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| PubMedSearch : Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| PubMedID: 24900696 |
| Title : Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors - Matheeussen_2012_Clin.Chim.Acta_413_456 |
| Author(s) : Matheeussen V , Lambeir AM , Jungraithmayr W , Gomez N , Mc Entee K , Van der Veken P , Scharpe S , De Meester I |
| Ref : Clinica Chimica Acta , 413 :456 , 2012 |
| Abstract : Matheeussen_2012_Clin.Chim.Acta_413_456 |
| ESTHER : Matheeussen_2012_Clin.Chim.Acta_413_456 |
| PubMedSearch : Matheeussen_2012_Clin.Chim.Acta_413_456 |
| PubMedID: 22093941 |
| Title : P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy - Van der Veken_2012_J.Med.Chem_55_9856 |
| Author(s) : Van der Veken P , Fulop V , Rea D , Gerard M , Van Elzen R , Joossens J , Cheng JD , Baekelandt V , De Meester I , Lambeir AM , Augustyns K |
| Ref : Journal of Medicinal Chemistry , 55 :9856 , 2012 |
| Abstract : Van der Veken_2012_J.Med.Chem_55_9856 |
| ESTHER : Van der Veken_2012_J.Med.Chem_55_9856 |
| PubMedSearch : Van der Veken_2012_J.Med.Chem_55_9856 |
| PubMedID: 23121075 |
| Gene_locus related to this paper: pig-ppce |
| Title : Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP\/prolyl oligopeptidase (PREP)-selectivity - Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| Author(s) : Ryabtsova O , Jansen K , Van Goethem S , Joossens J , Cheng JD , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :3412 , 2012 |
| Abstract : Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| ESTHER : Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| PubMedSearch : Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| PubMedID: 22525314 |
| Title : The effect of prolyl oligopeptidase inhibition on extracellular acetylcholine and dopamine levels in the rat striatum - Jalkanen_2012_Neurochem.Int_60_301 |
| Author(s) : Jalkanen AJ , Piepponen TP , Hakkarainen JJ , De Meester I , Lambeir AM , Forsberg MM |
| Ref : Neurochem Int , 60 :301 , 2012 |
| Abstract : Jalkanen_2012_Neurochem.Int_60_301 |
| ESTHER : Jalkanen_2012_Neurochem.Int_60_301 |
| PubMedSearch : Jalkanen_2012_Neurochem.Int_60_301 |
| PubMedID: 22210165 |
| Title : Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? - Van Goethem_2011_J.Med.Chem_54_5737 |
| Author(s) : Van Goethem S , Matheeussen V , Joossens J , Lambeir AM , Chen X , De Meester I , Haemers A , Augustyns K , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 54 :5737 , 2011 |
| Abstract : Van Goethem_2011_J.Med.Chem_54_5737 |
| ESTHER : Van Goethem_2011_J.Med.Chem_54_5737 |
| PubMedSearch : Van Goethem_2011_J.Med.Chem_54_5737 |
| PubMedID: 21711053 |
| Gene_locus related to this paper: human-DPP8 , human-DPP9 |
| Title : Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries - Matheeussen_2011_Biol.Chem_392_189 |
| Author(s) : Matheeussen V , Baerts L , De Meyer G , De Keulenaer G , Van der Veken P , Augustyns K , Dubois V , Scharpe S , De Meester I |
| Ref : Biol Chem , 392 :189 , 2011 |
| Abstract : Matheeussen_2011_Biol.Chem_392_189 |
| ESTHER : Matheeussen_2011_Biol.Chem_392_189 |
| PubMedSearch : Matheeussen_2011_Biol.Chem_392_189 |
| PubMedID: 21194356 |
| Title : Application of the dipeptidyl peptidase IV (DPPIV\/CD26) based prodrug approach to different amine-containing drugs - Diez-Torrubia_2010_J.Med.Chem_53_559 |
| Author(s) : Diez-Torrubia A , Garcia-Aparicio C , Cabrera S , De Meester I , Balzarini J , Camarasa MJ , Velazquez S |
| Ref : Journal of Medicinal Chemistry , 53 :559 , 2010 |
| Abstract : Diez-Torrubia_2010_J.Med.Chem_53_559 |
| ESTHER : Diez-Torrubia_2010_J.Med.Chem_53_559 |
| PubMedSearch : Diez-Torrubia_2010_J.Med.Chem_53_559 |
| PubMedID: 20000418 |
| Title : Dipeptidyl peptidase 9 (DPP9) from bovine testes: identification and characterization as the short form by mass spectrometry - Dubois_2010_Biochim.Biophys.Acta_1804_781 |
| Author(s) : Dubois V , Lambeir AM , Vandamme S , Matheeussen V , Guisez Y , Scharpe S , De Meester I |
| Ref : Biochimica & Biophysica Acta , 1804 :781 , 2010 |
| Abstract : Dubois_2010_Biochim.Biophys.Acta_1804_781 |
| ESTHER : Dubois_2010_Biochim.Biophys.Acta_1804_781 |
| PubMedSearch : Dubois_2010_Biochim.Biophys.Acta_1804_781 |
| PubMedID: 20026260 |
| Title : Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues - Dubois_2009_J.Histochem.Cytochem_57_531 |
| Author(s) : Dubois V , Van Ginneken C , De Cock H , Lambeir AM , Van der Veken P , Augustyns K , Chen X , Scharpe S , De Meester I |
| Ref : Journal of Histochemistry & Cytochemistry , 57 :531 , 2009 |
| Abstract : Dubois_2009_J.Histochem.Cytochem_57_531 |
| ESTHER : Dubois_2009_J.Histochem.Cytochem_57_531 |
| PubMedSearch : Dubois_2009_J.Histochem.Cytochem_57_531 |
| PubMedID: 19188489 |
| Gene_locus related to this paper: rat-dpp9 |
| Title : Dipeptidyl-peptidase IV and B-type natriuretic peptide. From bench to bedside - Vanderheyden_2009_Clin.Chem.Lab.Med_47_248 |
| Author(s) : Vanderheyden M , Bartunek J , Goethals M , Verstreken S , Lambeir AM , De Meester I , Scharpe S |
| Ref : Clinical Chemistry & Laboratory Medicine , 47 :248 , 2009 |
| Abstract : Vanderheyden_2009_Clin.Chem.Lab.Med_47_248 |
| ESTHER : Vanderheyden_2009_Clin.Chem.Lab.Med_47_248 |
| PubMedSearch : Vanderheyden_2009_Clin.Chem.Lab.Med_47_248 |
| PubMedID: 19327104 |
| Title : A CD26-controlled cell surface cascade for regulation of T cell motility and chemokine signals - Liu_2009_J.Immunol_183_3616 |
| Author(s) : Liu Z , Christensson M , Forslow A , De Meester I , Sundqvist KG |
| Ref : J Immunol , 183 :3616 , 2009 |
| Abstract : Liu_2009_J.Immunol_183_3616 |
| ESTHER : Liu_2009_J.Immunol_183_3616 |
| PubMedSearch : Liu_2009_J.Immunol_183_3616 |
| PubMedID: 19687096 |
| Title : Dipeptidyl peptidases and related proteins: multifaceted markers and therapeutic targets - |
| Author(s) : De Meester I , Scharpe S , Lambeir AM |
| Ref : Clinical Chemistry & Laboratory Medicine , 47 :245 , 2009 |
| PubMedID: 19327103 |
| Title : In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma - Jost_2009_Biochem.Pharmacol_77_228 |
| Author(s) : Jost MM , Lamerz J , Tammen H , Menzel C , De Meester I , Lambeir AM , Augustyns K , Scharpe S , Zucht HD , Rose H , Jurgens M , Schulz-Knappe P , Budde P |
| Ref : Biochemical Pharmacology , 77 :228 , 2009 |
| Abstract : Jost_2009_Biochem.Pharmacol_77_228 |
| ESTHER : Jost_2009_Biochem.Pharmacol_77_228 |
| PubMedSearch : Jost_2009_Biochem.Pharmacol_77_228 |
| PubMedID: 18940185 |
| Title : DPP4 inhibitors for diabetes--what next? - Lambeir_2008_Biochem.Pharmacol_76_1637 |
| Author(s) : Lambeir AM , Scharpe S , De Meester I |
| Ref : Biochemical Pharmacology , 76 :1637 , 2008 |
| Abstract : Lambeir_2008_Biochem.Pharmacol_76_1637 |
| ESTHER : Lambeir_2008_Biochem.Pharmacol_76_1637 |
| PubMedSearch : Lambeir_2008_Biochem.Pharmacol_76_1637 |
| PubMedID: 18755155 |
| Title : Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes - Dubois_2008_Front.Biosci_13_3558 |
| Author(s) : Dubois V , Lambeir AM , Van der Veken P , Augustyns K , Creemers J , Chen X , Scharpe S , De Meester I |
| Ref : Front Biosci , 13 :3558 , 2008 |
| Abstract : Dubois_2008_Front.Biosci_13_3558 |
| ESTHER : Dubois_2008_Front.Biosci_13_3558 |
| PubMedSearch : Dubois_2008_Front.Biosci_13_3558 |
| PubMedID: 18508455 |
| Title : Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors - Van Goethem_2008_Bioorg.Med.Chem.Lett_18_4159 |
| Author(s) : Van Goethem S , Van der Veken P , Dubois V , Soroka A , Lambeir AM , Chen X , Haemers A , Scharpe S , De Meester I , Augustyns K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :4159 , 2008 |
| Abstract : Van Goethem_2008_Bioorg.Med.Chem.Lett_18_4159 |
| ESTHER : Van Goethem_2008_Bioorg.Med.Chem.Lett_18_4159 |
| PubMedSearch : Van Goethem_2008_Bioorg.Med.Chem.Lett_18_4159 |
| PubMedID: 18556198 |
| Title : Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads - Van der Veken_2008_Bioorg.Med.Chem.Lett_18_4154 |
| Author(s) : Van der Veken P , De Meester I , Dubois V , Soroka A , Van Goethem S , Maes MB , Brandt I , Lambeir AM , Chen X , Haemers A , Scharpe S , Augustyns K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :4154 , 2008 |
| Abstract : Van der Veken_2008_Bioorg.Med.Chem.Lett_18_4154 |
| ESTHER : Van der Veken_2008_Bioorg.Med.Chem.Lett_18_4154 |
| PubMedSearch : Van der Veken_2008_Bioorg.Med.Chem.Lett_18_4154 |
| PubMedID: 18556199 |
| Title : Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates - Van der Veken_2007_J.Med.Chem_50_5568 |
| Author(s) : Van der Veken P , Soroka A , Brandt I , Chen YS , Maes MB , Lambeir AM , Chen X , Haemers A , Scharpe S , Augustyns K , De Meester I |
| Ref : Journal of Medicinal Chemistry , 50 :5568 , 2007 |
| Abstract : Van der Veken_2007_J.Med.Chem_50_5568 |
| ESTHER : Van der Veken_2007_J.Med.Chem_50_5568 |
| PubMedSearch : Van der Veken_2007_J.Med.Chem_50_5568 |
| PubMedID: 17958345 |
| Title : Dipeptidyl peptidase 8\/9-like activity in human leukocytes - Maes_2007_J.Leukoc.Biol_81_1252 |
| Author(s) : Maes MB , Dubois V , Brandt I , Lambeir AM , Van der Veken P , Augustyns K , Cheng JD , Chen X , Scharpe S , De Meester I |
| Ref : J Leukoc Biol , 81 :1252 , 2007 |
| Abstract : Maes_2007_J.Leukoc.Biol_81_1252 |
| ESTHER : Maes_2007_J.Leukoc.Biol_81_1252 |
| PubMedSearch : Maes_2007_J.Leukoc.Biol_81_1252 |
| PubMedID: 17287297 |
| Title : Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines - Soroka_2006_Bioorg.Med.Chem.Lett_16_4777 |
| Author(s) : Soroka A , Van der Veken P , De Meester I , Lambeir AM , Maes MB , Scharpe S , Haemers A , Augustyns K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :4777 , 2006 |
| Abstract : Soroka_2006_Bioorg.Med.Chem.Lett_16_4777 |
| ESTHER : Soroka_2006_Bioorg.Med.Chem.Lett_16_4777 |
| PubMedSearch : Soroka_2006_Bioorg.Med.Chem.Lett_16_4777 |
| PubMedID: 16844373 |
| Title : Design and discovery of a novel dipeptidyl-peptidase IV (CD26)-based prodrug approach - Garcia-Aparicio_2006_J.Med.Chem_49_5339 |
| Author(s) : Garcia-Aparicio C , Bonache MC , De Meester I , San-Felix A , Balzarini J , Camarasa MJ , Velazquez S |
| Ref : Journal of Medicinal Chemistry , 49 :5339 , 2006 |
| Abstract : Garcia-Aparicio_2006_J.Med.Chem_49_5339 |
| ESTHER : Garcia-Aparicio_2006_J.Med.Chem_49_5339 |
| PubMedSearch : Garcia-Aparicio_2006_J.Med.Chem_49_5339 |
| PubMedID: 16913724 |
| Title : In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII - |
| Author(s) : Maes MB , Lambeir AM , Van der Veken P , De Winter B , Augustyns K , Scharpe S , De Meester I |
| Ref : Advances in Experimental Medicine & Biology , 575 :73 , 2006 |
| PubMedID: 16700510 |
| Title : Peptide substrates of dipeptidyl peptidases - |
| Author(s) : Brandt I , Lambeir AM , Maes MB , Scharpe S , De Meester I |
| Ref : Advances in Experimental Medicine & Biology , 575 :3 , 2006 |
| PubMedID: 16700503 |
| Title : Ischemia\/reperfusion injury: The role of CD26\/dipeptidyl-peptidase-IV-inhibition in lung transplantation - Zhai_2006_Transplant.Proc_38_3369 |
| Author(s) : Zhai W , Cardell M , De Meester I , Augustyns K , Hillinger S , Inci I , Arni S , Jungraithmayr W , Scharpe S , Weder W , Korom S |
| Ref : Transplant Proc , 38 :3369 , 2006 |
| Abstract : Zhai_2006_Transplant.Proc_38_3369 |
| ESTHER : Zhai_2006_Transplant.Proc_38_3369 |
| PubMedSearch : Zhai_2006_Transplant.Proc_38_3369 |
| PubMedID: 17175274 |
| Title : Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form - Brandt_2006_Clin.Chem_52_82 |
| Author(s) : Brandt I , Lambeir AM , Ketelslegers JM , Vanderheyden M , Scharpe S , De Meester I |
| Ref : Clinical Chemistry , 52 :82 , 2006 |
| Abstract : Brandt_2006_Clin.Chem_52_82 |
| ESTHER : Brandt_2006_Clin.Chem_52_82 |
| PubMedSearch : Brandt_2006_Clin.Chem_52_82 |
| PubMedID: 16254193 |
| Title : Dipeptidyl peptidase II and leukocyte cell death - Maes_2006_Biochem.Pharmacol_72_70 |
| Author(s) : Maes MB , Martinet W , Schrijvers DM , Van der Veken P , De Meyer GR , Augustyns K , Lambeir AM , Scharpe S , De Meester I |
| Ref : Biochemical Pharmacology , 72 :70 , 2006 |
| Abstract : Maes_2006_Biochem.Pharmacol_72_70 |
| ESTHER : Maes_2006_Biochem.Pharmacol_72_70 |
| PubMedSearch : Maes_2006_Biochem.Pharmacol_72_70 |
| PubMedID: 16725115 |
| Title : Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases - Van der Veken_2005_J.Med.Chem_48_1768 |
| Author(s) : Van der Veken P , Senten K , Kertesz I , De Meester I , Lambeir AM , Maes MB , Scharpe S , Haemers A , Augustyns K |
| Ref : Journal of Medicinal Chemistry , 48 :1768 , 2005 |
| Abstract : Van der Veken_2005_J.Med.Chem_48_1768 |
| ESTHER : Van der Veken_2005_J.Med.Chem_48_1768 |
| PubMedSearch : Van der Veken_2005_J.Med.Chem_48_1768 |
| PubMedID: 15771423 |
| Title : Search for substrates for prolyl oligopeptidase in porcine brain - Brandt_2005_Peptides_26_2536 |
| Author(s) : Brandt I , De Vriendt K , Devreese B , Van Beeumen J , Van Dongen W , Augustyns K , De Meester I , Scharpe S , Lambeir AM |
| Ref : Peptides , 26 :2536 , 2005 |
| Abstract : Brandt_2005_Peptides_26_2536 |
| ESTHER : Brandt_2005_Peptides_26_2536 |
| PubMedSearch : Brandt_2005_Peptides_26_2536 |
| PubMedID: 15996789 |
| Title : Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile) - Brandt_2005_Biochem.Pharmacol_70_134 |
| Author(s) : Brandt I , Joossens J , Chen X , Maes MB , Scharpe S , De Meester I , Lambeir AM |
| Ref : Biochemical Pharmacology , 70 :134 , 2005 |
| Abstract : Brandt_2005_Biochem.Pharmacol_70_134 |
| ESTHER : Brandt_2005_Biochem.Pharmacol_70_134 |
| PubMedSearch : Brandt_2005_Biochem.Pharmacol_70_134 |
| PubMedID: 15907807 |
| Title : Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)\/dipeptidyl peptidase 7 (DPP7) - Maes_2005_Biochem.J_386_315 |
| Author(s) : Maes MB , Lambeir AM , Gilany K , Senten K , Van der Veken P , Leiting B , Augustyns K , Scharpe S , De Meester I |
| Ref : Biochemical Journal , 386 :315 , 2005 |
| Abstract : Maes_2005_Biochem.J_386_315 |
| ESTHER : Maes_2005_Biochem.J_386_315 |
| PubMedSearch : Maes_2005_Biochem.J_386_315 |
| PubMedID: 15487984 |
| Gene_locus related to this paper: human-DPP7 |
| Title : Expression, purification and preliminary crystallographic analysis of dipeptidyl peptidase IV from Porphyromonas gingivalis - Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871 |
| Author(s) : Rea D , Lambeir AM , Kumagai Y , De Meester I , Scharpe S , Fulop V |
| Ref : Acta Crystallographica D Biol Crystallogr , 60 :1871 , 2004 |
| Abstract : Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871 |
| ESTHER : Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871 |
| PubMedSearch : Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871 |
| PubMedID: 15388936 |
| Gene_locus related to this paper: porgi-DPP |
| Title : Gamma-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors - Senten_2004_J.Med.Chem_47_2906 |
| Author(s) : Senten K , Van der Veken P , De Meester I , Lambeir AM , Scharpe S , Haemers A , Augustyns K |
| Ref : Journal of Medicinal Chemistry , 47 :2906 , 2004 |
| Abstract : Senten_2004_J.Med.Chem_47_2906 |
| ESTHER : Senten_2004_J.Med.Chem_47_2906 |
| PubMedSearch : Senten_2004_J.Med.Chem_47_2906 |
| PubMedID: 15139769 |
| Title : Exploration of the active site of dipeptidyl peptidase IV from Porphyromonas gingivalis. Comparison with the human enzyme - |
| Author(s) : Lambeir AM , Rea D , Fulop V , Kumagai Y , Augustyns K , De Meester I , Haemers A , Scharpe S |
| Ref : Advances in Experimental Medicine & Biology , 524 :29 , 2003 |
| PubMedID: 12675220 |
| Title : Rapid parallel synthesis of dipeptide diphenyl phosphonate esters as inhibitors of dipeptidyl peptidases - Senten_2003_J.Comb.Chem_5_336 |
| Author(s) : Senten K , Daniels L , Van der Veken P , De Meester I , Lambeir AM , Scharpe S , Haemers A , Augustyns K |
| Ref : J Comb Chem , 5 :336 , 2003 |
| Abstract : Senten_2003_J.Comb.Chem_5_336 |
| ESTHER : Senten_2003_J.Comb.Chem_5_336 |
| PubMedSearch : Senten_2003_J.Comb.Chem_5_336 |
| PubMedID: 12739951 |
| Title : Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases - Senten_2003_J.Med.Chem_46_5005 |
| Author(s) : Senten K , Van der Veken P , De Meester I , Lambeir AM , Scharpe S , Haemers A , Augustyns K |
| Ref : Journal of Medicinal Chemistry , 46 :5005 , 2003 |
| Abstract : Senten_2003_J.Med.Chem_46_5005 |
| ESTHER : Senten_2003_J.Med.Chem_46_5005 |
| PubMedSearch : Senten_2003_J.Med.Chem_46_5005 |
| PubMedID: 14584950 |
| Title : Dipeptidyl peptidase IV substrates. An update on in vitro peptide hydrolysis by human DPPIV - |
| Author(s) : De Meester I , Lambeir AM , Proost P , Scharpe S |
| Ref : Advances in Experimental Medicine & Biology , 524 :3 , 2003 |
| PubMedID: 12675218 |
| Title : Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV - Lambeir_2003_Crit.Rev.Clin.Lab.Sci_40_209 |
| Author(s) : Lambeir AM , Durinx C , Scharpe S , De Meester I |
| Ref : Crit Rev Clin Lab Sci , 40 :209 , 2003 |
| Abstract : Lambeir_2003_Crit.Rev.Clin.Lab.Sci_40_209 |
| ESTHER : Lambeir_2003_Crit.Rev.Clin.Lab.Sci_40_209 |
| PubMedSearch : Lambeir_2003_Crit.Rev.Clin.Lab.Sci_40_209 |
| PubMedID: 12892317 |
| Title : Kinetic investigation of chemokine truncation by CD26\/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family - Lambeir_2001_J.Biol.Chem_276_29839 |
| Author(s) : Lambeir AM , Proost P , Durinx C , Bal G , Senten K , Augustyns K , Scharpe S , Van Damme J , De Meester I |
| Ref : Journal of Biological Chemistry , 276 :29839 , 2001 |
| Abstract : Lambeir_2001_J.Biol.Chem_276_29839 |
| ESTHER : Lambeir_2001_J.Biol.Chem_276_29839 |
| PubMedSearch : Lambeir_2001_J.Biol.Chem_276_29839 |
| PubMedID: 11390394 |
| Title : Kinetic study of the processing by dipeptidyl-peptidase IV\/CD26 of neuropeptides involved in pancreatic insulin secretion - Lambeir_2001_FEBS.Lett_507_327 |
| Author(s) : Lambeir AM , Durinx C , Proost P , Van Damme J , Scharpe S , De Meester I |
| Ref : FEBS Letters , 507 :327 , 2001 |
| Abstract : Lambeir_2001_FEBS.Lett_507_327 |
| ESTHER : Lambeir_2001_FEBS.Lett_507_327 |
| PubMedSearch : Lambeir_2001_FEBS.Lett_507_327 |
| PubMedID: 11696365 |
| Title : Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26\/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides - Durinx_2000_Eur.J.Biochem_267_5608 |
| Author(s) : Durinx C , Lambeir AM , Bosmans E , Falmagne JB , Berghmans R , Haemers A , Scharpe S , De Meester I |
| Ref : European Journal of Biochemistry , 267 :5608 , 2000 |
| Abstract : Durinx_2000_Eur.J.Biochem_267_5608 |
| ESTHER : Durinx_2000_Eur.J.Biochem_267_5608 |
| PubMedSearch : Durinx_2000_Eur.J.Biochem_267_5608 |
| PubMedID: 10951221 |
| Title : Structure-activity relationship of diaryl phosphonate esters as potent irreversible dipeptidyl peptidase IV inhibitors - Belyaev_1999_J.Med.Chem_42_1041 |
| Author(s) : Belyaev A , Zhang X , Augustyns K , Lambeir AM , De Meester I , Vedernikova I , Scharpe S , Haemers A |
| Ref : Journal of Medicinal Chemistry , 42 :1041 , 1999 |
| Abstract : Belyaev_1999_J.Med.Chem_42_1041 |
| ESTHER : Belyaev_1999_J.Med.Chem_42_1041 |
| PubMedSearch : Belyaev_1999_J.Med.Chem_42_1041 |
| PubMedID: 10090787 |
| Title : Development and evaluation of peptide-based prolyl oligopeptidase inhibitors--introduction of N-benzyloxycarbonyl-prolyl-3- fluoropyrrolidine as a lead in inhibitor design - Goossens_1997_Eur.J.Biochem_250_177 |
| Author(s) : Goossens F , Vanhoof G , De Meester I , Augustyns K , Borloo M , Tourwe D , Haemers A , Scharpe S |
| Ref : European Journal of Biochemistry , 250 :177 , 1997 |
| Abstract : Goossens_1997_Eur.J.Biochem_250_177 |
| ESTHER : Goossens_1997_Eur.J.Biochem_250_177 |
| PubMedSearch : Goossens_1997_Eur.J.Biochem_250_177 |
| PubMedID: 9432007 |
| Title : In vivo inhibition of dipeptidyl peptidase IV activity by pro-pro-diphenyl-phosphonate (Prodipine) - De Meester_1997_Biochem.Pharmacol_54_173 |
| Author(s) : De Meester I , Belyaev A , Lambeir AM , De Meyer GR , Van Osselaer N , Haemers A , Scharpe S |
| Ref : Biochemical Pharmacology , 54 :173 , 1997 |
| Abstract : De Meester_1997_Biochem.Pharmacol_54_173 |
| ESTHER : De Meester_1997_Biochem.Pharmacol_54_173 |
| PubMedSearch : De Meester_1997_Biochem.Pharmacol_54_173 |
| PubMedID: 9296364 |
| Title : The effects of CD26\/DPP IV-targeted therapy on acute allograft rejection - |
| Author(s) : Korom S , De Meester I , Onodera K , Stadlbauer TH , Borloo M , Lambeir AM , Kupiec-Weglinski JW |
| Ref : Transplant Proc , 29 :1274 , 1997 |
| PubMedID: 9123303 |
| Title : A prediction of DPP IV\/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasma - Lambeir_1997_Biochim.Biophys.Acta_1340_215 |
| Author(s) : Lambeir AM , Diaz Pereira JF , Chacon P , Vermeulen G , Heremans K , Devreese B , Van Beeumen J , De Meester I , Scharpe S |
| Ref : Biochimica & Biophysica Acta , 1340 :215 , 1997 |
| Abstract : Lambeir_1997_Biochim.Biophys.Acta_1340_215 |
| ESTHER : Lambeir_1997_Biochim.Biophys.Acta_1340_215 |
| PubMedSearch : Lambeir_1997_Biochim.Biophys.Acta_1340_215 |
| PubMedID: 9252108 |
| Title : Use of immobilized adenosine deaminase (EC 3.5.4.4) for the rapid purification of native human CD26\/dipeptidyl peptidase IV (EC 3.4.14.5) - de Meester_1996_J.Immunol.Methods_189_99 |
| Author(s) : De Meester I , Vanhoof G , Lambeir AM , Scharpe S |
| Ref : Journal of Immunological Methodsods , 189 :99 , 1996 |
| Abstract : de Meester_1996_J.Immunol.Methods_189_99 |
| ESTHER : de Meester_1996_J.Immunol.Methods_189_99 |
| PubMedSearch : de Meester_1996_J.Immunol.Methods_189_99 |
| PubMedID: 8576585 |
| Title : Dipeptide-derived diphenyl phosphonate esters: mechanism-based inhibitors of dipeptidyl peptidase IV - Lambeir_1996_Biochim.Biophys.Acta_1290_76 |
| Author(s) : Lambeir AM , Borloo M , De Meester I , Belyaev A , Augustyns K , Hendriks D , Scharpe S , Haemers A |
| Ref : Biochimica & Biophysica Acta , 1290 :76 , 1996 |
| Abstract : Lambeir_1996_Biochim.Biophys.Acta_1290_76 |
| ESTHER : Lambeir_1996_Biochim.Biophys.Acta_1290_76 |
| PubMedSearch : Lambeir_1996_Biochim.Biophys.Acta_1290_76 |
| PubMedID: 8645710 |
| Title : The purification, characterization and analysis of primary and secondary-structure of prolyl oligopeptidase from human lymphocytes. Evidence that the enzyme belongs to the alpha\/beta hydrolase fold family - Goossens_1995_Eur.J.Biochem_233_432 |
| Author(s) : Goossens F , De Meester I , Vanhoof G , Hendriks D , Vriend G , Scharpe S |
| Ref : European Journal of Biochemistry , 233 :432 , 1995 |
| Abstract : Goossens_1995_Eur.J.Biochem_233_432 |
| ESTHER : Goossens_1995_Eur.J.Biochem_233_432 |
| PubMedSearch : Goossens_1995_Eur.J.Biochem_233_432 |
| PubMedID: 7588785 |
| Gene_locus related to this paper: human-PREP |
| Title : Purified and cell-bound CD26: enzymatic inhibition, antibody binding profile, and expression on T cells in relation to other surface markers - Scharpe_1994_Verh.K.Acad.Geneeskd.Belg_56_537 |
| Author(s) : Scharpe S , De Meester I |
| Ref : Verh K Acad Geneeskd Belg , 56 :537 , 1994 |
| Abstract : Scharpe_1994_Verh.K.Acad.Geneeskd.Belg_56_537 |
| ESTHER : Scharpe_1994_Verh.K.Acad.Geneeskd.Belg_56_537 |
| PubMedSearch : Scharpe_1994_Verh.K.Acad.Geneeskd.Belg_56_537 |
| PubMedID: 7892748 |
| Title : Cloning and sequence analysis of the gene encoding human lymphocyte prolyl endopeptidase - Vanhoof_1994_Gene_149_363 |
| Author(s) : Vanhoof G , Goossens F , Hendriks L , De Meester I , Hendriks D , Vriend G , Van Broeckhoven C , Scharpe S |
| Ref : Gene , 149 :363 , 1994 |
| Abstract : Vanhoof_1994_Gene_149_363 |
| ESTHER : Vanhoof_1994_Gene_149_363 |
| PubMedSearch : Vanhoof_1994_Gene_149_363 |
| PubMedID: 7959018 |
| Gene_locus related to this paper: human-PREP |