Full name :
First name :
Mail :
Zip Code :
City :
Country :
Email :
Phone :
Fax :
Website :
Directory :
| Title : Evaluation of water-soluble Mannich base prodrugs of 2,3,4,5-tetrahydroazepino[4,3-b]indol-1(6H)-one as multitarget-directed agents for Alzheimer's disease - Purgatorio_2021_ChemMedChem_16_589 |
| Author(s) : Purgatorio R , de Candia M , Catto M , Rullo M , Pisani L , Denora N , Carrieri A , Nevskaya AA , Voskressensky LG , Altomare CD |
| Ref : ChemMedChem , 16 :589 , 2021 |
| Abstract : Purgatorio_2021_ChemMedChem_16_589 |
| ESTHER : Purgatorio_2021_ChemMedChem_16_589 |
| PubMedSearch : Purgatorio_2021_ChemMedChem_16_589 |
| PubMedID: 33156950 |
| Title : Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents - Titov_2021_ACS.Chem.Neurosci__ |
| Author(s) : Titov AA , Kobzev MS , Catto M , de Candia M , Gambacorta N , Denora N , Pisani L , Nicolotti O , Borisova TN , Varlamov AV , Voskressensky LG , Altomare CD |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : Titov_2021_ACS.Chem.Neurosci__ |
| ESTHER : Titov_2021_ACS.Chem.Neurosci__ |
| PubMedSearch : Titov_2021_ACS.Chem.Neurosci__ |
| PubMedID: 33395258 |
| Title : Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor - Catto_2020_ACS.Med.Chem.Lett_11_869 |
| Author(s) : Catto M , Pisani L , De la Mora E , Belviso BD , Mangiatordi GF , Pinto A , Palma A , Denora N , Caliandro R , Colletier JP , Silman I , Nicolotti O , Altomare CD |
| Ref : ACS Med Chem Lett , 11 :869 , 2020 |
| Abstract : Catto_2020_ACS.Med.Chem.Lett_11_869 |
| ESTHER : Catto_2020_ACS.Med.Chem.Lett_11_869 |
| PubMedSearch : Catto_2020_ACS.Med.Chem.Lett_11_869 |
| PubMedID: 32435398 |
| Title : Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3 - Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| Author(s) : Oukoloff K , Coquelle N , Bartolini M , Naldi M , Le Guevel R , Bach S , Josselin B , Ruchaud S , Catto M , Pisani L , Denora N , Iacobazzi RM , Silman I , Sussman JL , Buron F , Colletier JP , Jean L , Routier S , Renard PY |
| Ref : Eur Journal of Medicinal Chemistry , 168 :58 , 2019 |
| Abstract : Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| ESTHER : Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| PubMedSearch : Oukoloff_2019_Eur.J.Med.Chem_168_58 |
| PubMedID: 30798053 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors - Pisani_2018_Eur.J.Med.Chem_161_292 |
| Author(s) : Pisani L , Iacobazzi RM , Catto M , Rullo M , Farina R , Denora N , Cellamare S , Altomare CD |
| Ref : Eur Journal of Medicinal Chemistry , 161 :292 , 2018 |
| Abstract : Pisani_2018_Eur.J.Med.Chem_161_292 |
| ESTHER : Pisani_2018_Eur.J.Med.Chem_161_292 |
| PubMedSearch : Pisani_2018_Eur.J.Med.Chem_161_292 |
| PubMedID: 30366255 |
| Title : The position of fluorine in CP-118,954 affects AChE inhibition potency and PET imaging quantification for AChE expression in the rat brain - Lee_2017_Eur.J.Pharm.Sci_109_209 |
| Author(s) : Lee BC , Moon BS , Park HS , Jung JH , Park DD , de Candia M , Denora N , Altomare CD , Kim SE |
| Ref : Eur J Pharm Sci , 109 :209 , 2017 |
| Abstract : Lee_2017_Eur.J.Pharm.Sci_109_209 |
| ESTHER : Lee_2017_Eur.J.Pharm.Sci_109_209 |
| PubMedSearch : Lee_2017_Eur.J.Pharm.Sci_109_209 |
| PubMedID: 28818531 |
| Title : New azepino[4,3-b]indole derivatives as nanomolar selective inhibitors of human butyrylcholinesterase showing protective effects against NMDA-induced neurotoxicity - de Candia_2016_Eur.J.Med.Chem_125_288 |
| Author(s) : de Candia M , Zaetta G , Denora N , Tricarico D , Majellaro M , Cellamare S , Altomare CD |
| Ref : Eur Journal of Medicinal Chemistry , 125 :288 , 2016 |
| Abstract : de Candia_2016_Eur.J.Med.Chem_125_288 |
| ESTHER : de Candia_2016_Eur.J.Med.Chem_125_288 |
| PubMedSearch : de Candia_2016_Eur.J.Med.Chem_125_288 |
| PubMedID: 27688184 |
| Title : Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents - Pisani_2016_J.Med.Chem_59_6791 |
| Author(s) : Pisani L , Farina R , Catto M , Iacobazzi RM , Nicolotti O , Cellamare S , Mangiatordi GF , Denora N , Soto-Otero R , Siragusa L , Altomare CD , Carotti A |
| Ref : Journal of Medicinal Chemistry , 59 :6791 , 2016 |
| Abstract : Pisani_2016_J.Med.Chem_59_6791 |
| ESTHER : Pisani_2016_J.Med.Chem_59_6791 |
| PubMedSearch : Pisani_2016_J.Med.Chem_59_6791 |
| PubMedID: 27347731 |
| Title : Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif - Pisani_2016_Molecules_21_ |
| Author(s) : Pisani L , Farina R , Soto-Otero R , Denora N , Mangiatordi GF , Nicolotti O , Mendez-Alvarez E , Altomare CD , Catto M , Carotti A |
| Ref : Molecules , 21 : , 2016 |
| Abstract : Pisani_2016_Molecules_21_ |
| ESTHER : Pisani_2016_Molecules_21_ |
| PubMedSearch : Pisani_2016_Molecules_21_ |
| PubMedID: 26999091 |
| Title : Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases - Farina_2015_J.Med.Chem_58_5561 |
| Author(s) : Farina R , Pisani L , Catto M , Nicolotti O , Gadaleta D , Denora N , Soto-Otero R , Mendez-Alvarez E , Passos CS , Muncipinto G , Altomare CD , Nurisso A , Carrupt PA , Carotti A |
| Ref : Journal of Medicinal Chemistry , 58 :5561 , 2015 |
| Abstract : Farina_2015_J.Med.Chem_58_5561 |
| ESTHER : Farina_2015_J.Med.Chem_58_5561 |
| PubMedSearch : Farina_2015_J.Med.Chem_58_5561 |
| PubMedID: 26107513 |
| Title : Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and beta-Amyloid (Abeta) Aggregation - Tonelli_2015_ChemMedChem_10_1040 |
| Author(s) : Tonelli M , Catto M , Tasso B , Novelli F , Canu C , Iusco G , Pisani L , Stradis AD , Denora N , Sparatore A , Boido V , Carotti A , Sparatore F |
| Ref : ChemMedChem , 10 :1040 , 2015 |
| Abstract : Tonelli_2015_ChemMedChem_10_1040 |
| ESTHER : Tonelli_2015_ChemMedChem_10_1040 |
| PubMedSearch : Tonelli_2015_ChemMedChem_10_1040 |
| PubMedID: 25924599 |