Report for Dijkstra BW

General

Full name : Dijkstra Bauke W

First name : Bauke W

Mail : Laboratory of Biophysical Chemistry, Centre of Life Sciences, University of Groningen, Nijenborgh 7, 9747 AG Groningen

Zip Code :

City :

Country : The Netherlands

Email : B.W.Dijkstra@rug.nl

Phone :

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Website :

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References (39)

Title : Structural and time-resolved mechanistic investigations of protein hydrolysis by the acidic proline-specific endoprotease from Aspergillus niger - Pijning_2023_Protein.Sci__e4856
Author(s) : Pijning T , Vujicic-zagar A , Laan JV , Jong RM , Ramirez-Palacios C , Vente A , Edens L , Dijkstra BW
Ref : Protein Science , :e4856 , 2023
Abstract : Pijning_2023_Protein.Sci__e4856
ESTHER : Pijning_2023_Protein.Sci__e4856
PubMedSearch : Pijning_2023_Protein.Sci__e4856
PubMedID: 38059672
Gene_locus related to this paper: aspng-AnPEP

Title : Crystal structures of two Bacillus carboxylesterases with different enantioselectivities - Rozeboom_2014_Biochim.Biophys.Acta_1844_567
Author(s) : Rozeboom HJ , Godinho LF , Nardini M , Quax WJ , Dijkstra BW
Ref : Biochimica & Biophysica Acta , 1844 :567 , 2014
Abstract : Rozeboom_2014_Biochim.Biophys.Acta_1844_567
ESTHER : Rozeboom_2014_Biochim.Biophys.Acta_1844_567
PubMedSearch : Rozeboom_2014_Biochim.Biophys.Acta_1844_567
PubMedID: 24418394
Gene_locus related to this paper: bacsu-cbxnp , bacsu-ybfk

Title : Enhancement of the enantioselectivity of carboxylesterase A by structure-based mutagenesis - Godinho_2012_J.Biotechnol_158_36
Author(s) : Godinho LF , Reis CR , Rozeboom HJ , Dekker FJ , Dijkstra BW , Poelarends GJ , Quax WJ
Ref : J Biotechnol , 158 :36 , 2012
Abstract : Godinho_2012_J.Biotechnol_158_36
ESTHER : Godinho_2012_J.Biotechnol_158_36
PubMedSearch : Godinho_2012_J.Biotechnol_158_36
PubMedID: 22248594
Gene_locus related to this paper: bacsu-cbxnp

Title : Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention - Augustyniak_2012_Protein.Sci_21_487
Author(s) : Augustyniak W , Brzezinska AA , Pijning T , Wienk H , Boelens R , Dijkstra BW , Reetz MT
Ref : Protein Science , 21 :487 , 2012
Abstract : Augustyniak_2012_Protein.Sci_21_487
ESTHER : Augustyniak_2012_Protein.Sci_21_487
PubMedSearch : Augustyniak_2012_Protein.Sci_21_487
PubMedID: 22267088
Gene_locus related to this paper: bacsu-lip

Title : Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain - Levisson_2009_J.Mol.Biol_385_949
Author(s) : Levisson M , Sun L , Hendriks S , Swinkels P , Akveld T , Bultema JB , Barendregt A , van den Heuvel RH , Dijkstra BW , Van der Oost J , Kengen SW
Ref : Journal of Molecular Biology , 385 :949 , 2009
Abstract : Levisson_2009_J.Mol.Biol_385_949
ESTHER : Levisson_2009_J.Mol.Biol_385_949
PubMedSearch : Levisson_2009_J.Mol.Biol_385_949
PubMedID: 19013466
Gene_locus related to this paper: thema-TM0033

Title : Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity - Boersma_2008_Chem.Biol_15_782
Author(s) : Boersma YL , Pijning T , Bosma MS , van der Sloot AM , Godinho LF , Droge MJ , Winter RT , van Pouderoyen G , Dijkstra BW , Quax WJ
Ref : Chemical Biology , 15 :782 , 2008
Abstract : Boersma_2008_Chem.Biol_15_782
ESTHER : Boersma_2008_Chem.Biol_15_782
PubMedSearch : Boersma_2008_Chem.Biol_15_782
PubMedID: 18721749
Gene_locus related to this paper: bacsu-lip

Title : Crystallization and preliminary crystallographic analysis of an esterase with a novel domain from the hyperthermophile Thermotoga maritima - Sun_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_777
Author(s) : Sun L , Levisson M , Hendriks S , Akveld T , Kengen SW , Dijkstra BW , Van der Oost J
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 63 :777 , 2007
Abstract : Sun_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_777
ESTHER : Sun_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_777
PubMedSearch : Sun_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_777
PubMedID: 17768353
Gene_locus related to this paper: thema-TM0033

Title : Structural basis of phospholipase activity of Staphylococcus hyicus lipase - Tiesinga_2007_J.Mol.Biol_371_447
Author(s) : Tiesinga JJ , van Pouderoyen G , Nardini M , Ransac S , Dijkstra BW
Ref : Journal of Molecular Biology , 371 :447 , 2007
Abstract : Tiesinga_2007_J.Mol.Biol_371_447
ESTHER : Tiesinga_2007_J.Mol.Biol_371_447
PubMedSearch : Tiesinga_2007_J.Mol.Biol_371_447
PubMedID: 17582438
Gene_locus related to this paper: stahy-lipas

Title : Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme - Barends_2006_J.Biol.Chem_281_5804
Author(s) : Barends TR , Polderman-Tijmes JJ , Jekel PA , Williams C , Wybenga G , Janssen DB , Dijkstra BW
Ref : Journal of Biological Chemistry , 281 :5804 , 2006
Abstract : Barends_2006_J.Biol.Chem_281_5804
ESTHER : Barends_2006_J.Biol.Chem_281_5804
PubMedSearch : Barends_2006_J.Biol.Chem_281_5804
PubMedID: 16377627
Gene_locus related to this paper: acepa-AEHA

Title : Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection - Droge_2006_Chembiochem_7_149
Author(s) : Droge MJ , Boersma YL , van Pouderoyen G , Vrenken TE , Ruggeberg CJ , Reetz MT , Dijkstra BW , Quax WJ
Ref : Chembiochem , 7 :149 , 2006
Abstract : Droge_2006_Chembiochem_7_149
ESTHER : Droge_2006_Chembiochem_7_149
PubMedSearch : Droge_2006_Chembiochem_7_149
PubMedID: 16342303
Gene_locus related to this paper: bacsu-lip

Title : Three-dimensional structures of enzymes useful for beta-lactam antibiotic production - Barends_2004_Curr.Opin.Biotechnol_15_356
Author(s) : Barends TR , Yoshida H , Dijkstra BW
Ref : Curr Opin Biotechnol , 15 :356 , 2004
Abstract : Barends_2004_Curr.Opin.Biotechnol_15_356
ESTHER : Barends_2004_Curr.Opin.Biotechnol_15_356
PubMedSearch : Barends_2004_Curr.Opin.Biotechnol_15_356
PubMedID: 15358004

Title : The sequence and crystal structure of the alpha -amino acid ester hydrolase from Xanthomonas citri define a new family of beta -lactam antibiotic acylases - Barends_2003_J.Biol.Chem_278_23076
Author(s) : Barends TR , Polderman-Tijmes JJ , Jekel PA , Hensgens CM , de Vries EJ , Janssen DB , Dijkstra BW
Ref : Journal of Biological Chemistry , 278 :23076 , 2003
Abstract : Barends_2003_J.Biol.Chem_278_23076
ESTHER : Barends_2003_J.Biol.Chem_278_23076
PubMedSearch : Barends_2003_J.Biol.Chem_278_23076
PubMedID: 12684501
Gene_locus related to this paper: xanax-GAA

Title : Acetobacter turbidans alpha-amino acid ester hydrolase: merohedral twinning in P21 obscured by pseudo-translational NCS - Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_2237
Author(s) : Barends TR , Dijkstra BW
Ref : Acta Crystallographica D Biol Crystallogr , 59 :2237 , 2003
Abstract : Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_2237
ESTHER : Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_2237
PubMedSearch : Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_2237
PubMedID: 14646082
Gene_locus related to this paper: acepa-AEHA

Title : Structure and mechanism of bacterial dehalogenases: different ways to cleave a carbon-halogen bond - de Jong_2003_Curr.Opin.Struct.Biol_13_722
Author(s) : de Jong RM , Dijkstra BW
Ref : Current Opinion in Structural Biology , 13 :722 , 2003
Abstract : de Jong_2003_Curr.Opin.Struct.Biol_13_722
ESTHER : de Jong_2003_Curr.Opin.Struct.Biol_13_722
PubMedSearch : de Jong_2003_Curr.Opin.Struct.Biol_13_722
PubMedID: 14675551

Title : Catalysis and regulation - from structure to function -
Author(s) : Dijkstra BW , Matthews RG
Ref : Current Opinion in Structural Biology , 13 :706 , 2003
PubMedID: 14675548

Title : X-ray analysis of two antibiotic-synthesizing bacterial ester hydrolases: preliminary results - Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_158
Author(s) : Barends TR , Hensgens CM , Polderman-Tijmes JJ , Jekel PA , de Vries E , Janssen DB , Dijkstra BW
Ref : Acta Crystallographica D Biol Crystallogr , 59 :158 , 2003
Abstract : Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_158
ESTHER : Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_158
PubMedSearch : Barends_2003_Acta.Crystallogr.D.Biol.Crystallogr_59_158
PubMedID: 12499556

Title : The crystal structure of Bacillus subtilis lipase: a minimal alpha\/beta hydrolase fold enzyme - van Pouderoyen_2001_J.Mol.Biol_309_215
Author(s) : van Pouderoyen G , Eggert T , Jaeger KE , Dijkstra BW
Ref : Journal of Molecular Biology , 309 :215 , 2001
Abstract : van Pouderoyen_2001_J.Mol.Biol_309_215
ESTHER : van Pouderoyen_2001_J.Mol.Biol_309_215
PubMedSearch : van Pouderoyen_2001_J.Mol.Biol_309_215
PubMedID: 11491291
Gene_locus related to this paper: bacsu-lip

Title : Lipolytic enzymes LipA and LipB from Bacillus subtilis differ in regulation of gene expression, biochemical properties, and three-dimensional structure - Eggert_2001_FEBS.Lett_502_89
Author(s) : Eggert T , van Pouderoyen G , Dijkstra BW , Jaeger KE
Ref : FEBS Letters , 502 :89 , 2001
Abstract : Eggert_2001_FEBS.Lett_502_89
ESTHER : Eggert_2001_FEBS.Lett_502_89
PubMedSearch : Eggert_2001_FEBS.Lett_502_89
PubMedID: 11583117
Gene_locus related to this paper: bacsu-lip , bacsu-LIPB

Title : Directed evolution of an enantioselective lipase - Liebeton_2000_Chem.Biol_7_709
Author(s) : Liebeton K , Zonta A , Schimossek K , Nardini M , Lang D , Dijkstra BW , Reetz MT , Jaeger KE
Ref : Chemical Biology , 7 :709 , 2000
Abstract : Liebeton_2000_Chem.Biol_7_709
ESTHER : Liebeton_2000_Chem.Biol_7_709
PubMedSearch : Liebeton_2000_Chem.Biol_7_709
PubMedID: 10980451

Title : Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases - Nardini_2000_J.Biol.Chem_275_31219
Author(s) : Nardini M , Lang DA , Liebeton K , Jaeger KE , Dijkstra BW
Ref : Journal of Biological Chemistry , 275 :31219 , 2000
Abstract : Nardini_2000_J.Biol.Chem_275_31219
ESTHER : Nardini_2000_J.Biol.Chem_275_31219
PubMedSearch : Nardini_2000_J.Biol.Chem_275_31219
PubMedID: 10893416
Gene_locus related to this paper: pseae-llipa

Title : Crystallographic and kinetic evidence of a collision complex formed during halide import in haloalkane dehalogenase - Pikkemaat_1999_Biochemistry_38_12052
Author(s) : Pikkemaat MG , Ridder IS , Rozeboom HJ , Kalk KH , Dijkstra BW , Janssen DB
Ref : Biochemistry , 38 :12052 , 1999
Abstract : Pikkemaat_1999_Biochemistry_38_12052
ESTHER : Pikkemaat_1999_Biochemistry_38_12052
PubMedSearch : Pikkemaat_1999_Biochemistry_38_12052
PubMedID: 10508409
Gene_locus related to this paper: xanau-halo1

Title : Haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 refined at 1.15 A resolution - Ridder_1999_Acta.Crystallogr.D.Biol.Crystallogr_55_1273
Author(s) : Ridder IS , Rozeboom HJ , Dijkstra BW
Ref : Acta Crystallographica D Biol Crystallogr , 55 :1273 , 1999
Abstract : Ridder_1999_Acta.Crystallogr.D.Biol.Crystallogr_55_1273
ESTHER : Ridder_1999_Acta.Crystallogr.D.Biol.Crystallogr_55_1273
PubMedSearch : Ridder_1999_Acta.Crystallogr.D.Biol.Crystallogr_55_1273
PubMedID: 10393294
Gene_locus related to this paper: xanau-halo1

Title : The x-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1. An enzyme to detoxify harmful epoxides - Nardini_1999_J.Biol.Chem_274_14579
Author(s) : Nardini M , Ridder IS , Rozeboom HJ , Kalk KH , Rink R , Janssen DB , Dijkstra BW
Ref : Journal of Biological Chemistry , 274 :14579 , 1999
Abstract : Nardini_1999_J.Biol.Chem_274_14579
ESTHER : Nardini_1999_J.Biol.Chem_274_14579
PubMedSearch : Nardini_1999_J.Biol.Chem_274_14579
PubMedID: 10329649
Gene_locus related to this paper: agrra-echA

Title : Mutation of tyrosine residues involved in the alkylation half reaction of epoxide hydrolase from Agrobacterium radiobacter AD1 results in improved enantioselectivity - Rink_1999_J.Am.Chem.Soc_121_7417
Author(s) : Rink R , Lutje Spelberg JH , Pieters RJ , Kingma J , Nardini M , Kellogg RM , Dijkstra BW , Janssen DB
Ref : Journal of the American Chemical Society , 121 :7417 , 1999
Abstract : Rink_1999_J.Am.Chem.Soc_121_7417
ESTHER : Rink_1999_J.Am.Chem.Soc_121_7417
PubMedSearch : Rink_1999_J.Am.Chem.Soc_121_7417
PubMedID:
Gene_locus related to this paper: agrra-echA

Title : Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases - Jaeger_1999_Annu.Rev.Microbiol_53_315
Author(s) : Jaeger KE , Dijkstra BW , Reetz MT
Ref : Annu Rev Microbiol , 53 :315 , 1999
Abstract : Jaeger_1999_Annu.Rev.Microbiol_53_315
ESTHER : Jaeger_1999_Annu.Rev.Microbiol_53_315
PubMedSearch : Jaeger_1999_Annu.Rev.Microbiol_53_315
PubMedID: 10547694

Title : Alpha\/beta hydrolase fold enzymes: the family keeps growing - Nardini_1999_Curr.Opin.Struct.Biol_9_732
Author(s) : Nardini M , Dijkstra BW
Ref : Current Opinion in Structural Biology , 9 :732 , 1999
Abstract : Nardini_1999_Curr.Opin.Struct.Biol_9_732
ESTHER : Nardini_1999_Curr.Opin.Struct.Biol_9_732
PubMedSearch : Nardini_1999_Curr.Opin.Struct.Biol_9_732
PubMedID: 10607665

Title : Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding site - Krooshof_1998_Biochemistry_37_15013
Author(s) : Krooshof GH , Ridder IS , Tepper AW , Vos GJ , Rozeboom HJ , Kalk KH , Dijkstra BW , Janssen DB
Ref : Biochemistry , 37 :15013 , 1998
Abstract : Krooshof_1998_Biochemistry_37_15013
ESTHER : Krooshof_1998_Biochemistry_37_15013
PubMedSearch : Krooshof_1998_Biochemistry_37_15013
PubMedID: 9790663
Gene_locus related to this paper: xanau-halo1

Title : Structural basis of the chiral selectivity of Pseudomonas cepacia lipase - Lang_1998_Eur.J.Biochem_254_333
Author(s) : Lang DA , Mannesse ML , De Haas GH , Verheij HM , Dijkstra BW
Ref : European Journal of Biochemistry , 254 :333 , 1998
Abstract : Lang_1998_Eur.J.Biochem_254_333
ESTHER : Lang_1998_Eur.J.Biochem_254_333
PubMedSearch : Lang_1998_Eur.J.Biochem_254_333
PubMedID: 9660188
Gene_locus related to this paper: burce-lipaa

Title : Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range - Schanstra_1996_Biochemistry_35_13186
Author(s) : Schanstra JP , Ridder IS , Heimeriks GJ , Rink R , Poelarends GJ , Kalk KH , Dijkstra BW , Janssen DB
Ref : Biochemistry , 35 :13186 , 1996
Abstract : Schanstra_1996_Biochemistry_35_13186
ESTHER : Schanstra_1996_Biochemistry_35_13186
PubMedSearch : Schanstra_1996_Biochemistry_35_13186
PubMedID: 8855957
Gene_locus related to this paper: xanau-halo1

Title : Crystallization and preliminary X-ray analysis of a lipase from Staphylococcus hyicus - Ransac_1995_J.Struct.Biol_114_153
Author(s) : Ransac S , Blaauw M , Dijkstra BW , Slotboom AT , Boots JW , Verheij HM
Ref : J Struct Biol , 114 :153 , 1995
Abstract : Ransac_1995_J.Struct.Biol_114_153
ESTHER : Ransac_1995_J.Struct.Biol_114_153
PubMedSearch : Ransac_1995_J.Struct.Biol_114_153
PubMedID: 7612398

Title : Crystallization and preliminary X-ray analysis of a lipase from Bacillus subtilis - Ransac_1994_J.Mol.Biol_238_857
Author(s) : Ransac S , Blaauw M , Lesuisse E , Schanck K , Colson C , Dijkstra BW
Ref : Journal of Molecular Biology , 238 :857 , 1994
Abstract : Ransac_1994_J.Mol.Biol_238_857
ESTHER : Ransac_1994_J.Mol.Biol_238_857
PubMedSearch : Ransac_1994_J.Mol.Biol_238_857
PubMedID: 8182756

Title : Bacterial lipases - Jaeger_1994_FEMS.Microbiol.Rev_15_29
Author(s) : Jaeger KE , Ransac S , Dijkstra BW , Colson C , van Heuvel M , Misset O
Ref : FEMS Microbiology Reviews , 15 :29 , 1994
Abstract : Jaeger_1994_FEMS.Microbiol.Rev_15_29
ESTHER : Jaeger_1994_FEMS.Microbiol.Rev_15_29
PubMedSearch : Jaeger_1994_FEMS.Microbiol.Rev_15_29
PubMedID: 7946464

Title : Non-covalent binding of the heavy atom compound [Au(CN)2]- at the halide binding site of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 - Verschueren_1993_FEBS.Lett_323_267
Author(s) : Verschueren KH , Franken SM , Rozeboom HJ , Kalk KH , Dijkstra BW
Ref : FEBS Letters , 323 :267 , 1993
Abstract : Verschueren_1993_FEBS.Lett_323_267
ESTHER : Verschueren_1993_FEBS.Lett_323_267
PubMedSearch : Verschueren_1993_FEBS.Lett_323_267
PubMedID: 8500621
Gene_locus related to this paper: xanau-halo1

Title : Topological characterization and modeling of the 3D structure of lipase from Pseudomonas aeruginosa - Jaeger_1993_FEBS.Lett_332_143
Author(s) : Jaeger KE , Ransac S , Koch HB , Ferrato F , Dijkstra BW
Ref : FEBS Letters , 332 :143 , 1993
Abstract : Jaeger_1993_FEBS.Lett_332_143
ESTHER : Jaeger_1993_FEBS.Lett_332_143
PubMedSearch : Jaeger_1993_FEBS.Lett_332_143
PubMedID: 8405431

Title : Refined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanism - Verschueren_1993_J.Mol.Biol_232_856
Author(s) : Verschueren KH , Franken SM , Rozeboom HJ , Kalk KH , Dijkstra BW
Ref : Journal of Molecular Biology , 232 :856 , 1993
Abstract : Verschueren_1993_J.Mol.Biol_232_856
ESTHER : Verschueren_1993_J.Mol.Biol_232_856
PubMedSearch : Verschueren_1993_J.Mol.Biol_232_856
PubMedID: 8355275

Title : Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase - Verschueren_1993_Nature_363_693
Author(s) : Verschueren KH , Seljee F , Rozeboom HJ , Kalk KH , Dijkstra BW
Ref : Nature , 363 :693 , 1993
Abstract : Verschueren_1993_Nature_363_693
ESTHER : Verschueren_1993_Nature_363_693
PubMedSearch : Verschueren_1993_Nature_363_693
PubMedID: 8515812
Gene_locus related to this paper: xanau-halo1

Title : Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site - Verschueren_1993_Biochemistry_32_9031
Author(s) : Verschueren KH , Kingma J , Rozeboom HJ , Kalk KH , Janssen DB , Dijkstra BW
Ref : Biochemistry , 32 :9031 , 1993
Abstract : Verschueren_1993_Biochemistry_32_9031
ESTHER : Verschueren_1993_Biochemistry_32_9031
PubMedSearch : Verschueren_1993_Biochemistry_32_9031
PubMedID: 8369276
Gene_locus related to this paper: xanau-halo1

Title : Crystal structure of haloalkane dehalogenase: an enzyme to detoxify halogenated alkanes - Franken_1991_EMBO.J_10_1297
Author(s) : Franken SM , Rozeboom HJ , Kalk KH , Dijkstra BW
Ref : EMBO Journal , 10 :1297 , 1991
Abstract : Franken_1991_EMBO.J_10_1297
ESTHER : Franken_1991_EMBO.J_10_1297
PubMedSearch : Franken_1991_EMBO.J_10_1297
PubMedID: 2026135
Gene_locus related to this paper: xanau-halo1

Title : Crystallization of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 - Rozeboom_1988_J.Mol.Biol_200_611
Author(s) : Rozeboom HJ , Kingma J , Janssen DB , Dijkstra BW
Ref : Journal of Molecular Biology , 200 :611 , 1988
Abstract : Rozeboom_1988_J.Mol.Biol_200_611
ESTHER : Rozeboom_1988_J.Mol.Biol_200_611
PubMedSearch : Rozeboom_1988_J.Mol.Biol_200_611
PubMedID: 3398051
Gene_locus related to this paper: xanau-halo1