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| Title : Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes - Madar_2006_J.Med.Chem_49_6416 |
| Author(s) : Madar DJ , Kopecka H , Pireh D , Yong H , Pei Z , Li X , Wiedeman PE , Djuric SW , von Geldern TW , Fickes MG , Bhagavatula L , McDermott T , Wittenberger S , Richards SJ , Longenecker KL , Stewart KD , Lubben TH , Ballaron SJ , Stashko MA , Long MA , Wells H , Zinker BA , Mika AK , Beno DW , Kempf-Grote AJ , Polakowski J , Segreti J , Reinhart GA , Fryer RM , Sham HL , Trevillyan JM |
| Ref : Journal of Medicinal Chemistry , 49 :6416 , 2006 |
| Abstract : Madar_2006_J.Med.Chem_49_6416 |
| ESTHER : Madar_2006_J.Med.Chem_49_6416 |
| PubMedSearch : Madar_2006_J.Med.Chem_49_6416 |
| PubMedID: 17034148 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides - Beebe_2004_Bioorg.Med.Chem.Lett_14_2417 |
| Author(s) : Beebe X , Yang F , Bui MH , Mitten MJ , Ma Z , Nilius AM , Djuric SW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :2417 , 2004 |
| Abstract : Beebe_2004_Bioorg.Med.Chem.Lett_14_2417 |
| ESTHER : Beebe_2004_Bioorg.Med.Chem.Lett_14_2417 |
| PubMedSearch : Beebe_2004_Bioorg.Med.Chem.Lett_14_2417 |
| PubMedID: 15109624 |
| Title : Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase - Penning_2003_Bioorg.Med.Chem.Lett_13_1137 |
| Author(s) : Penning TD , Chandrakumar NS , Desai BN , Djuric SW , Gasiecki AF , Malecha JW , Miyashiro JM , Russell MA , Askonas LJ , Gierse JK , Harding EI , Highkin MK , Kachur JF , Kim SH , Villani-Price D , Pyla EY , Ghoreishi-Haack NS , Smith WG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 13 :1137 , 2003 |
| Abstract : Penning_2003_Bioorg.Med.Chem.Lett_13_1137 |
| ESTHER : Penning_2003_Bioorg.Med.Chem.Lett_13_1137 |
| PubMedSearch : Penning_2003_Bioorg.Med.Chem.Lett_13_1137 |
| PubMedID: 12643929 |
| Title : Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase - Penning_2002_Bioorg.Med.Chem.Lett_12_3383 |
| Author(s) : Penning TD , Chandrakumar NS , Desai BN , Djuric SW , Gasiecki AF , Liang CD , Miyashiro JM , Russell MA , Askonas LJ , Gierse JK , Harding EI , Highkin MK , Kachur JF , Kim SH , Villani-Price D , Pyla EY , Ghoreishi-Haack NS , Smith WG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 12 :3383 , 2002 |
| Abstract : Penning_2002_Bioorg.Med.Chem.Lett_12_3383 |
| ESTHER : Penning_2002_Bioorg.Med.Chem.Lett_12_3383 |
| PubMedSearch : Penning_2002_Bioorg.Med.Chem.Lett_12_3383 |
| PubMedID: 12419366 |
| Title : Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase - Penning_2000_J.Med.Chem_43_721 |
| Author(s) : Penning TD , Chandrakumar NS , Chen BB , Chen HY , Desai BN , Djuric SW , Docter SH , Gasiecki AF , Haack RA , Miyashiro JM , Russell MA , Yu SS , Corley DG , Durley RC , Kilpatrick BF , Parnas BL , Askonas LJ , Gierse JK , Harding EI , Highkin MK , Kachur JF , Kim SH , Krivi GG , Villani-Price D , Pyla EY , Smith WG |
| Ref : Journal of Medicinal Chemistry , 43 :721 , 2000 |
| Abstract : Penning_2000_J.Med.Chem_43_721 |
| ESTHER : Penning_2000_J.Med.Chem_43_721 |
| PubMedSearch : Penning_2000_J.Med.Chem_43_721 |
| PubMedID: 10691697 |