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| Title : Monooxime Bispyridinium Reactivators Bearing Xylene Linker Synthesis and In Vitro Evaluation on Model of Organophosphate-Inhibited Acetylcholinesterase - Musilek_2016_Med.Chem_12_362 |
| Author(s) : Musilek K , Hambalek J , Holas O , Dohnal V , Kuca K |
| Ref : Med Chem , 12 :362 , 2016 |
| Abstract : Musilek_2016_Med.Chem_12_362 |
| ESTHER : Musilek_2016_Med.Chem_12_362 |
| PubMedSearch : Musilek_2016_Med.Chem_12_362 |
| PubMedID: 26427931 |
| Title : Development and validation of a FIA\/UV-vis method for pK determination of oxime based acetylcholinesterase reactivators - Musil_2015_J.Pharm.Biomed.Anal_117_240 |
| Author(s) : Musil K , Florianova V , Bucek P , Dohnal V , Kuca K , Musilek K |
| Ref : J Pharm Biomed Anal , 117 :240 , 2015 |
| Abstract : Musil_2015_J.Pharm.Biomed.Anal_117_240 |
| ESTHER : Musil_2015_J.Pharm.Biomed.Anal_117_240 |
| PubMedSearch : Musil_2015_J.Pharm.Biomed.Anal_117_240 |
| PubMedID: 26386953 |
| Title : Preparation, in vitro screening and molecular modelling of monoquaternary compounds related to the selective acetylcholinesterase inhibitor BW284c51 - Benek_2014_Med.Chem_11_21 |
| Author(s) : Benek O , Musilek K , Horova A , Dohnal V , Dolezal R , Kuca K |
| Ref : Med Chem , 11 :21 , 2014 |
| Abstract : Benek_2014_Med.Chem_11_21 |
| ESTHER : Benek_2014_Med.Chem_11_21 |
| PubMedSearch : Benek_2014_Med.Chem_11_21 |
| PubMedID: 24773345 |
| Title : Oxidative stress-mediated cytotoxicity and metabolism of T-2 toxin and deoxynivalenol in animals and humans: an update - Wu_2014_Arch.Toxicol_88_1309 |
| Author(s) : Wu QH , Wang X , Yang W , Nussler AK , Xiong LY , Kuca K , Dohnal V , Zhang XJ , Yuan ZH |
| Ref : Archives of Toxicology , 88 :1309 , 2014 |
| Abstract : Wu_2014_Arch.Toxicol_88_1309 |
| ESTHER : Wu_2014_Arch.Toxicol_88_1309 |
| PubMedSearch : Wu_2014_Arch.Toxicol_88_1309 |
| PubMedID: 24894432 |
| Title : selective monitoring of enzymatic activity of acetylcholinesterase by flow injection analysis with mass spectrometric detection - Dohnal_2013_Mil.Med.Sci.Lett_82_120 |
| Author(s) : Dohnal V , Dohnalova L , Jun D , Kuca K |
| Ref : Military Medical Science Letters , 82 :120 , 2013 |
| Abstract : Dohnal_2013_Mil.Med.Sci.Lett_82_120 |
| ESTHER : Dohnal_2013_Mil.Med.Sci.Lett_82_120 |
| PubMedSearch : Dohnal_2013_Mil.Med.Sci.Lett_82_120 |
| PubMedID: |
| Title : Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors--analogues of SAD-128 - Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| Author(s) : Musilek K , Roder J , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Opletalova V , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :150 , 2011 |
| Abstract : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| ESTHER : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| PubMedSearch : Musilek_2011_Bioorg.Med.Chem.Lett_21_150 |
| PubMedID: 21144749 |
| Title : Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment - Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| Author(s) : Komloova M , Musilek K , Horova A , Holas O , Dohnal V , Gunn-Moore F , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2505 , 2011 |
| Abstract : Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| ESTHER : Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| PubMedSearch : Komloova_2011_Bioorg.Med.Chem.Lett_21_2505 |
| PubMedID: 21397501 |
| Title : Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment - Musilek_2011_Eur.J.Med.Chem_46_811 |
| Author(s) : Musilek K , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Nachon F , Dolezal M , Kuca K |
| Ref : Eur Journal of Medicinal Chemistry , 46 :811 , 2011 |
| Abstract : Musilek_2011_Eur.J.Med.Chem_46_811 |
| ESTHER : Musilek_2011_Eur.J.Med.Chem_46_811 |
| PubMedSearch : Musilek_2011_Eur.J.Med.Chem_46_811 |
| PubMedID: 21236521 |
| Title : The preparation, in vitro screening and molecular docking of symmetrical bisquaternary cholinesterase inhibitors containing a but-(2E)-en-1,4-diyl connecting linkage - Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| Author(s) : Musilek K , Pavlikova R , Marek J , Komloova M , Holas O , Hrabinova M , Pohanka M , Dohnal V , Dolezal M , Gunn-Moore F , Kuca K |
| Ref : J Enzyme Inhib Med Chem , 26 :245 , 2011 |
| Abstract : Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| ESTHER : Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| PubMedSearch : Musilek_2011_J.Enzyme.Inhib.Med.Chem_26_245 |
| PubMedID: 21406034 |
| Title : Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking - Musilek_2011_Bioorg.Med.Chem_19_754 |
| Author(s) : Musilek K , Komloova M , Holas O , Horova A , Pohanka M , Gunn-Moore F , Dohnal V , Dolezal M , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry , 19 :754 , 2011 |
| Abstract : Musilek_2011_Bioorg.Med.Chem_19_754 |
| ESTHER : Musilek_2011_Bioorg.Med.Chem_19_754 |
| PubMedSearch : Musilek_2011_Bioorg.Med.Chem_19_754 |
| PubMedID: 21215642 |
| Title : Monooxime-monocarbamoyl Bispyridinium Xylene-Linked Reactivators of Acetylcholinesterase-Synthesis, In vitro and Toxicity Evaluation, and Docking Studies - Musilek_2010_ChemMedChem_5_247 |
| Author(s) : Musilek K , Holas O , Misik J , Pohanka M , Novotny L , Dohnal V , Opletalova V , Kuca K |
| Ref : ChemMedChem , 5 :247 , 2010 |
| Abstract : Musilek_2010_ChemMedChem_5_247 |
| ESTHER : Musilek_2010_ChemMedChem_5_247 |
| PubMedSearch : Musilek_2010_ChemMedChem_5_247 |
| PubMedID: 20058292 |
| Title : Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications - Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| Author(s) : Musilek K , Komloova M , Zavadova V , Holas O , Hrabinova M , Pohanka M , Dohnal V , Nachon F , Dolezal M , Kuca K , Jung YS |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1763 , 2010 |
| Abstract : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| ESTHER : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| PubMedSearch : Musilek_2010_Bioorg.Med.Chem.Lett_20_1763 |
| PubMedID: 20138518 |
| Title : Synthesis and in vitro evaluation of N-(Bromobut-3-en-2-yl)-7-methoxy-1,2,3,4-tetrahydroacridin-9-amine as a cholinesterase inhibitor with regard to Alzheimer's disease treatment - Korabecny_2010_Molecules_15_8804 |
| Author(s) : Korabecny J , Musilek K , Holas O , Nepovimova E , Jun D , Zemek F , Opletalova V , Patocka J , Dohnal V , Nachon F , Hroudova J , Fisar Z , Kuca K |
| Ref : Molecules , 15 :8804 , 2010 |
| Abstract : Korabecny_2010_Molecules_15_8804 |
| ESTHER : Korabecny_2010_Molecules_15_8804 |
| PubMedSearch : Korabecny_2010_Molecules_15_8804 |
| PubMedID: 21127466 |
| Title : Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease - Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| Author(s) : Korabecny J , Musilek K , Holas O , Binder J , Zemek F , Marek J , Pohanka M , Opletalova V , Dohnal V , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :6093 , 2010 |
| Abstract : Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| ESTHER : Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| PubMedSearch : Korabecny_2010_Bioorg.Med.Chem.Lett_20_6093 |
| PubMedID: 20817518 |
| Title : Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase - Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Opletalova V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 23 :70 , 2008 |
| Abstract : Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| ESTHER : Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| PubMedSearch : Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 |
| PubMedID: 18341256 |
| Title : Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase - Musilek_2008_Bioorg.Med.Chem_16_8218 |
| Author(s) : Musilek K , Kucera J , Jun D , Dohnal V , Opletalova V , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry , 16 :8218 , 2008 |
| Abstract : Musilek_2008_Bioorg.Med.Chem_16_8218 |
| ESTHER : Musilek_2008_Bioorg.Med.Chem_16_8218 |
| PubMedSearch : Musilek_2008_Bioorg.Med.Chem_16_8218 |
| PubMedID: 18676153 |
| Title : Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 22 :425 , 2007 |
| Abstract : Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| ESTHER : Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| PubMedSearch : Musilek_2007_J.Enzyme.Inhib.Med.Chem_22_425 |
| PubMedID: 17847708 |
| Title : Two step synthesis of a non-symmetric acetylcholinesterase reactivator - Musilek_2007_Molecules_12_1755 |
| Author(s) : Musilek K , Kuca K , Dohnal V , Jun D , Marek J , Koleckar V |
| Ref : Molecules , 12 :1755 , 2007 |
| Abstract : Musilek_2007_Molecules_12_1755 |
| ESTHER : Musilek_2007_Molecules_12_1755 |
| PubMedSearch : Musilek_2007_Molecules_12_1755 |
| PubMedID: 17960085 |
| Title : Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase - Musilek_2007_Bioorg.Med.Chem_15_6733 |
| Author(s) : Musilek K , Holas O , Jun D , Dohnal V , Gunn-Moore F , Opletalova V , Dolezal M , Kuca K |
| Ref : Bioorganic & Medicinal Chemistry , 15 :6733 , 2007 |
| Abstract : Musilek_2007_Bioorg.Med.Chem_15_6733 |
| ESTHER : Musilek_2007_Bioorg.Med.Chem_15_6733 |
| PubMedSearch : Musilek_2007_Bioorg.Med.Chem_15_6733 |
| PubMedID: 17764957 |
| Title : Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Opletalova V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :3172 , 2007 |
| Abstract : Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| ESTHER : Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| PubMedSearch : Musilek_2007_Bioorg.Med.Chem.Lett_17_3172 |
| PubMedID: 17383875 |
| Title : Synthesis of asymmetrical bispyridinium compounds bearing cyano-moiety and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase - Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| Author(s) : Musilek K , Holas O , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :5673 , 2006 |
| Abstract : Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| ESTHER : Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| PubMedSearch : Musilek_2006_Bioorg.Med.Chem.Lett_16_5673 |
| PubMedID: 16934462 |
| Title : [Synthesis of reactivators of phosphorylated acetylcholinesterase of bis-pyridiniumdialdoxime type with a 3-oxapentane connecting chain and their testing in vitro on a model of the enzyme inhibited by chlorpyrifos and methylchlorpyrifos] - Musilek_2006_Ceska.Slov.Farm_55_115 |
| Author(s) : Musilek K , Kuca K , Jun D , Dohnal V , Kim TH , Jung YS , Dolezal M |
| Ref : Ceska a Slovenska Farmacie , 55 :115 , 2006 |
| Abstract : Musilek_2006_Ceska.Slov.Farm_55_115 |
| ESTHER : Musilek_2006_Ceska.Slov.Farm_55_115 |
| PubMedSearch : Musilek_2006_Ceska.Slov.Farm_55_115 |
| PubMedID: 16838488 |
| Title : Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase - Musilek_2006_Bioorg.Med.Chem.Lett_16_622 |
| Author(s) : Musilek K , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :622 , 2006 |
| Abstract : Musilek_2006_Bioorg.Med.Chem.Lett_16_622 |
| ESTHER : Musilek_2006_Bioorg.Med.Chem.Lett_16_622 |
| PubMedSearch : Musilek_2006_Bioorg.Med.Chem.Lett_16_622 |
| PubMedID: 16288867 |
| Title : Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase - Musilek_2005_J.Enzyme.Inhib.Med.Chem_20_409 |
| Author(s) : Musilek K , Kuca K , Jun D , Dohnal V , Dolezal M |
| Ref : J Enzyme Inhib Med Chem , 20 :409 , 2005 |
| Abstract : Musilek_2005_J.Enzyme.Inhib.Med.Chem_20_409 |
| ESTHER : Musilek_2005_J.Enzyme.Inhib.Med.Chem_20_409 |
| PubMedSearch : Musilek_2005_J.Enzyme.Inhib.Med.Chem_20_409 |
| PubMedID: 16335048 |
| Title : Strategy for the development of new acetylcholinesterase reactivators - antidotes used for treatment of nerve agent poisonings - Kuca_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_429 |
| Author(s) : Kuca K , Cabal J , Jun D , Kassa J , Bartosova L , Kunesova G , Dohnal V |
| Ref : Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub , 149 :429 , 2005 |
| Abstract : Kuca_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_429 |
| ESTHER : Kuca_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_429 |
| PubMedSearch : Kuca_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_429 |
| PubMedID: 16601804 |
| Title : 1,3-Bis(2-hydroxyiminomethylpyridinium) propane as the potential reactivator of the acetylcholinesterase inhibited by nerve agents - Kuca_2004_Acta.Medica.(Hradec.Kralove)_47_167 |
| Author(s) : Kuca K , Dohnal V |
| Ref : Acta Medica (Hradec Kralove) , 47 :167 , 2004 |
| Abstract : Kuca_2004_Acta.Medica.(Hradec.Kralove)_47_167 |
| ESTHER : Kuca_2004_Acta.Medica.(Hradec.Kralove)_47_167 |
| PubMedSearch : Kuca_2004_Acta.Medica.(Hradec.Kralove)_47_167 |
| PubMedID: 15568733 |
| Title : Cyclodextrines as functional agents for decontamination of the skin contaminated by nerve agents - Cabal_2004_Acta.Medica.(Hradec.Kralove)_47_115 |
| Author(s) : Cabal J , Kuca K , Sevelova-Bartosova L , Dohnal V |
| Ref : Acta Medica (Hradec Kralove) , 47 :115 , 2004 |
| Abstract : Cabal_2004_Acta.Medica.(Hradec.Kralove)_47_115 |
| ESTHER : Cabal_2004_Acta.Medica.(Hradec.Kralove)_47_115 |
| PubMedSearch : Cabal_2004_Acta.Medica.(Hradec.Kralove)_47_115 |
| PubMedID: 15446361 |