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| Title : Pharmacokinetic, pharmacodynamic, and tolerability profiles of the dipeptidyl peptidase-4 inhibitor linagliptin: a 4-week multicenter, randomized, double-blind, placebo-controlled phase IIa study in Japanese type 2 diabetes patients - Horie_2011_Clin.Ther_33_973 |
| Author(s) : Horie Y , Kanada S , Watada H , Sarashina A , Taniguchi A , Hayashi N , Graefe-Mody EU , Woerle HJ , Dugi KA |
| Ref : Clin Ther , 33 :973 , 2011 |
| Abstract : Horie_2011_Clin.Ther_33_973 |
| ESTHER : Horie_2011_Clin.Ther_33_973 |
| PubMedSearch : Horie_2011_Clin.Ther_33_973 |
| PubMedID: 21723606 |
| Title : Pharmacokinetics and pharmacodynamics of single rising intravenous doses (0.5 mg-10 mg) and determination of absolute bioavailability of the dipeptidyl peptidase-4 inhibitor linagliptin (BI 1356) in healthy male subjects - Retlich_2010_Clin.Pharmacokinet_49_829 |
| Author(s) : Retlich S , Duval V , Ring A , Staab A , Huttner S , Jungnik A , Jaehde U , Dugi KA , Graefe-Mody U |
| Ref : Clinical Pharmacokinetics , 49 :829 , 2010 |
| Abstract : Retlich_2010_Clin.Pharmacokinet_49_829 |
| ESTHER : Retlich_2010_Clin.Pharmacokinet_49_829 |
| PubMedSearch : Retlich_2010_Clin.Pharmacokinet_49_829 |
| PubMedID: 21053992 |
| Title : Linagliptin (BI 1356), a potent and selective DPP-4 inhibitor, is safe and efficacious in combination with metformin in patients with inadequately controlled Type 2 diabetes - Forst_2010_Diabet.Med_27_1409 |
| Author(s) : Forst T , Uhlig-Laske B , Ring A , Graefe-Mody U , Friedrich C , Herbach K , Woerle HJ , Dugi KA |
| Ref : Diabet Med , 27 :1409 , 2010 |
| Abstract : Forst_2010_Diabet.Med_27_1409 |
| ESTHER : Forst_2010_Diabet.Med_27_1409 |
| PubMedSearch : Forst_2010_Diabet.Med_27_1409 |
| PubMedID: 21059094 |
| Title : Evaluation of the pharmacokinetic interaction between the dipeptidyl peptidase-4 inhibitor linagliptin and pioglitazone in healthy volunteers - Graefe-Mody_2010_Int.J.Clin.Pharmacol.Ther_48_652 |
| Author(s) : Graefe-Mody EU , Jungnik A , Ring A , Woerle HJ , Dugi KA |
| Ref : Int J Clinical Pharmacology & Therapeutics , 48 :652 , 2010 |
| Abstract : Graefe-Mody_2010_Int.J.Clin.Pharmacol.Ther_48_652 |
| ESTHER : Graefe-Mody_2010_Int.J.Clin.Pharmacol.Ther_48_652 |
| PubMedSearch : Graefe-Mody_2010_Int.J.Clin.Pharmacol.Ther_48_652 |
| PubMedID: 20875371 |
| Title : Pharmacokinetics, pharmacodynamics and tolerability of multiple oral doses of linagliptin, a dipeptidyl peptidase-4 inhibitor in male type 2 diabetes patients - Heise_2009_Diabetes.Obes.Metab_11_786 |
| Author(s) : Heise T , Graefe-Mody EU , Huttner S , Ring A , Trommeshauser D , Dugi KA |
| Ref : Diabetes Obes Metab , 11 :786 , 2009 |
| Abstract : Heise_2009_Diabetes.Obes.Metab_11_786 |
| ESTHER : Heise_2009_Diabetes.Obes.Metab_11_786 |
| PubMedSearch : Heise_2009_Diabetes.Obes.Metab_11_786 |
| PubMedID: 19476474 |
| Title : The proline 12 alanine substitution in the peroxisome proliferator--activated receptor-gamma2 gene is associated with lower lipoprotein lipase activity in vivo - Schneider_2002_Diabetes_51_867 |
| Author(s) : Schneider J , Kreuzer J , Hamann A , Nawroth PP , Dugi KA |
| Ref : Diabetes , 51 :867 , 2002 |
| Abstract : Schneider_2002_Diabetes_51_867 |
| ESTHER : Schneider_2002_Diabetes_51_867 |
| PubMedSearch : Schneider_2002_Diabetes_51_867 |
| PubMedID: 11872694 |
| Title : Homozygosity for two point mutations in the lipoprotein lipase (LPL) gene in a patient with familial LPL deficiency: LPL(Asp9-->Asn, Tyr262-->His) - Rouis_1996_J.Lipid.Res_37_651 |
| Author(s) : Rouis M , Lohse P , Dugi KA , Beg OU , Ronan R , Talley GD , Brunzell JD , Santamarina-Fojo S |
| Ref : J Lipid Res , 37 :651 , 1996 |
| Abstract : Rouis_1996_J.Lipid.Res_37_651 |
| ESTHER : Rouis_1996_J.Lipid.Res_37_651 |
| PubMedSearch : Rouis_1996_J.Lipid.Res_37_651 |
| PubMedID: 8728326 |
| Title : Analysis of protein structure-function in vivo. Adenovirus-mediated transfer of lipase lid mutants in hepatic lipase-deficient mice - Kobayashi_1996_J.Biol.Chem_271_26296 |
| Author(s) : Kobayashi J , Applebaum-Bowden D , Dugi KA , Brown DR , Kashyap VS , Parrott C , Duarte C , Maeda N , Santamarina-Fojo S |
| Ref : Journal of Biological Chemistry , 271 :26296 , 1996 |
| Abstract : Kobayashi_1996_J.Biol.Chem_271_26296 |
| ESTHER : Kobayashi_1996_J.Biol.Chem_271_26296 |
| PubMedSearch : Kobayashi_1996_J.Biol.Chem_271_26296 |
| PubMedID: 8824281 |
| Title : A novel A-->G mutation in intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency - Brand_1996_J.Lipid.Res_37_1213 |
| Author(s) : Brand K , Dugi KA , Brunzell JD , Nevin DN , Santamarina-Fojo S |
| Ref : J Lipid Res , 37 :1213 , 1996 |
| Abstract : Brand_1996_J.Lipid.Res_37_1213 |
| ESTHER : Brand_1996_J.Lipid.Res_37_1213 |
| PubMedSearch : Brand_1996_J.Lipid.Res_37_1213 |
| PubMedID: 8808756 |
| Title : Human hepatic and lipoprotein lipase: the loop covering the catalytic site mediates lipase substrate specificity - Dugi_1995_J.Biol.Chem_270_25396 |
| Author(s) : Dugi KA , Dichek HL , Santamarina-Fojo S |
| Ref : Journal of Biological Chemistry , 270 :25396 , 1995 |
| Abstract : Dugi_1995_J.Biol.Chem_270_25396 |
| ESTHER : Dugi_1995_J.Biol.Chem_270_25396 |
| PubMedSearch : Dugi_1995_J.Biol.Chem_270_25396 |
| PubMedID: 7592706 |
| Title : A novel missense mutation in the C-terminal domain of lipoprotein lipase (Glu410-->Val) leads to enzyme inactivation and familial chylomicronemia - Previato_1994_J.Lipid.Res_35_1552 |
| Author(s) : Previato L , Guardamagna O , Dugi KA , Ronan R , Talley GD , Santamarina-Fojo S , Brewer HB, Jr. |
| Ref : J Lipid Res , 35 :1552 , 1994 |
| Abstract : Previato_1994_J.Lipid.Res_35_1552 |
| ESTHER : Previato_1994_J.Lipid.Res_35_1552 |
| PubMedSearch : Previato_1994_J.Lipid.Res_35_1552 |
| PubMedID: 7806969 |
| Gene_locus related to this paper: human-LPL |