Report for Eades W

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References (4)

Title : Covalent CES2 Inhibitors Protect against Reduced Formation of Intestinal Organoids by the Anticancer Drug Irinotecan - Eades_2022_Curr.Drug.Metab__
Author(s) : Eades W , Liu W , Shen Y , Shi Z , Yan B
Ref : Curr Drug Metab , : , 2022
Abstract : Eades_2022_Curr.Drug.Metab__
ESTHER : Eades_2022_Curr.Drug.Metab__
PubMedSearch : Eades_2022_Curr.Drug.Metab__
PubMedID: 36515038

Title : The Covid-19 oral drug Molnupiravir is a CES2 substrate: potential drug-drug interactions and impact of CES2 genetic polymorphism in vitro - Shen_2022_Drug.Metab.Dispos__
Author(s) : Shen Y , Eades W , Liu W , Yan B
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2022
Abstract : Shen_2022_Drug.Metab.Dispos__
ESTHER : Shen_2022_Drug.Metab.Dispos__
PubMedSearch : Shen_2022_Drug.Metab.Dispos__
PubMedID: 35790245

Title : Remdesivir potently inhibits carboxylesterase-2 through covalent modifications: signifying strong drug-drug interactions - Shen_2021_Fundam.Clin.Pharmacol_35_432
Author(s) : Shen Y , Eades W , Yan B
Ref : Fundamental & Clinical Toxicology , 35 :432 , 2021
Abstract : Shen_2021_Fundam.Clin.Pharmacol_35_432
ESTHER : Shen_2021_Fundam.Clin.Pharmacol_35_432
PubMedSearch : Shen_2021_Fundam.Clin.Pharmacol_35_432
PubMedID: 33369768
Gene_locus related to this paper: human-CES2

Title : The COVID-19 medicine remdesivir is therapeutically activated by carboxylesterase-1 AND excessive hydrolysis increases cytotoxicity - Shen_2021_Hepatol.Commun__
Author(s) : Shen Y , Eades W , Yan B
Ref : Hepatol Commun , : , 2021
Abstract : Shen_2021_Hepatol.Commun__
ESTHER : Shen_2021_Hepatol.Commun__
PubMedSearch : Shen_2021_Hepatol.Commun__
PubMedID: 34230903