Report for Enz A

General

Full name : Enz Albert

First name : Albert

Mail : Novartis Pharma Inc., Preclinical Research, Bldg. 386 762, CH-4002 Basel

Zip Code :

City :

Country : Switzerland

Email :

Phone : 61-324-4705

Fax : 61-324-4787

Website :

Directory :

References (25)

Title : Pharmacokinetics and pharmacodynamics of the novel daily rivastigmine transdermal patch compared with twice-daily capsules in Alzheimer's disease patients - Lefevre_2008_Clin.Pharmacol.Ther_83_106
Author(s) : Lefevre G , Sedek G , Jhee SS , Leibowitz MT , Huang HL , Enz A , Maton S , Ereshefsky L , Pommier F , Schmidli H , Appel-Dingemanse S
Ref : Clinical Pharmacology & Therapeutics , 83 :106 , 2008
Abstract : Lefevre_2008_Clin.Pharmacol.Ther_83_106
ESTHER : Lefevre_2008_Clin.Pharmacol.Ther_83_106
PubMedSearch : Lefevre_2008_Clin.Pharmacol.Ther_83_106
PubMedID: 17522596

Title : N1phenethyl-norcymserine, a selective butyrylcholinesterase inhibitor, increases acetylcholine release in rat cerebral cortex: a comparison with donepezil and rivastigmine - Cerbai_2007_Eur.J.Pharmacol_572_142
Author(s) : Cerbai F , Giovannini MG , Melani C , Enz A , Pepeu G
Ref : European Journal of Pharmacology , 572 :142 , 2007
Abstract : Cerbai_2007_Eur.J.Pharmacol_572_142
ESTHER : Cerbai_2007_Eur.J.Pharmacol_572_142
PubMedSearch : Cerbai_2007_Eur.J.Pharmacol_572_142
PubMedID: 17643410

Title : Targeting acetylcholinesterase and butyrylcholinesterase in dementia - Lane_2006_Int.J.Neuropsychopharmacol_9_101
Author(s) : Lane RM , Potkin SG , Enz A
Ref : Int J Neuropsychopharmacol , 9 :101 , 2006
Abstract : Lane_2006_Int.J.Neuropsychopharmacol_9_101
ESTHER : Lane_2006_Int.J.Neuropsychopharmacol_9_101
PubMedSearch : Lane_2006_Int.J.Neuropsychopharmacol_9_101
PubMedID: 16083515

Title : Cholinesterases: roles in the brain during health and disease - Ballard_2005_Curr.Alzheimer.Res_2_307
Author(s) : Ballard CG , Greig NH , Guillozet-Bongaarts AL , Enz A , Darvesh S
Ref : Curr Alzheimer Res , 2 :307 , 2005
Abstract : Ballard_2005_Curr.Alzheimer.Res_2_307
ESTHER : Ballard_2005_Curr.Alzheimer.Res_2_307
PubMedSearch : Ballard_2005_Curr.Alzheimer.Res_2_307
PubMedID: 15974896

Title : Rivastigmine as a modulator of the neuronal glutamate transporter rEAAC1 mRNA expression - Andin_2005_Dement.Geriatr.Cogn.Disord_19_18
Author(s) : Andin J , Enz A , Gentsch C , Marcusson J
Ref : Dementia & Geriatric Cognitive Disorders , 19 :18 , 2005
Abstract : Andin_2005_Dement.Geriatr.Cogn.Disord_19_18
ESTHER : Andin_2005_Dement.Geriatr.Cogn.Disord_19_18
PubMedSearch : Andin_2005_Dement.Geriatr.Cogn.Disord_19_18
PubMedID: 15383741

Title : A simple, rapid and sensitive method for simultaneous determination of rivastigmine and its major metabolite NAP 226-90 in rat brain and plasma by reversed-phase liquid chromatography coupled to electrospray ionization mass spectrometry - Enz_2004_Biomed.Chromatogr_18_160
Author(s) : Enz A , Chappuis A , Dattler A
Ref : Biomedical Chromatography , 18 :160 , 2004
Abstract : Enz_2004_Biomed.Chromatogr_18_160
ESTHER : Enz_2004_Biomed.Chromatogr_18_160
PubMedSearch : Enz_2004_Biomed.Chromatogr_18_160
PubMedID: 15103701

Title : Co-administration of memantine has no effect on the in vitro or ex vivo determined acetylcholinesterase inhibition of rivastigmine in the rat brain - Enz_2004_Neuropharmacol_47_408
Author(s) : Enz A , Gentsch C
Ref : Neuropharmacology , 47 :408 , 2004
Abstract : Enz_2004_Neuropharmacol_47_408
ESTHER : Enz_2004_Neuropharmacol_47_408
PubMedSearch : Enz_2004_Neuropharmacol_47_408
PubMedID: 15275830

Title : Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis - Boncristiano_2002_J.Neurosci_22_3234
Author(s) : Boncristiano S , Calhoun ME , Kelly PH , Pfeifer M , Bondolfi L , Stalder M , Phinney AL , Abramowski D , Sturchler-Pierrat C , Enz A , Sommer B , Staufenbiel M , Jucker M
Ref : Journal of Neuroscience , 22 :3234 , 2002
Abstract : Boncristiano_2002_J.Neurosci_22_3234
ESTHER : Boncristiano_2002_J.Neurosci_22_3234
PubMedSearch : Boncristiano_2002_J.Neurosci_22_3234
PubMedID: 11943824

Title : Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit - Giacobini_2002_J.Neural.Transm.(Vienna)_109_1053
Author(s) : Giacobini E , Spiegel R , Enz A , Veroff AE , Cutler NR
Ref : J Neural Transm (Vienna) , 109 :1053 , 2002
Abstract : Giacobini_2002_J.Neural.Transm.(Vienna)_109_1053
ESTHER : Giacobini_2002_J.Neural.Transm.(Vienna)_109_1053
PubMedSearch : Giacobini_2002_J.Neural.Transm.(Vienna)_109_1053
PubMedID: 12111443

Title : Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine - Bar-On_2002_Biochemistry_41_3555
Author(s) : Bar-On P , Millard CB , Harel M , Dvir H , Enz A , Sussman JL , Silman I
Ref : Biochemistry , 41 :3555 , 2002
Abstract : Bar-On_2002_Biochemistry_41_3555
ESTHER : Bar-On_2002_Biochemistry_41_3555
PubMedSearch : Bar-On_2002_Biochemistry_41_3555
PubMedID: 11888271
Gene_locus related to this paper: torca-ACHE

Title : Synthesis and acetylcholinesterase inhibition of 5-desamino huperzine A derivatives - Hogenauer_2001_Bioorg.Med.Chem.Lett_11_2627
Author(s) : Hogenauer K , Baumann K , Enz A , Mulzer J
Ref : Bioorganic & Medicinal Chemistry Lett , 11 :2627 , 2001
Abstract : Hogenauer_2001_Bioorg.Med.Chem.Lett_11_2627
ESTHER : Hogenauer_2001_Bioorg.Med.Chem.Lett_11_2627
PubMedSearch : Hogenauer_2001_Bioorg.Med.Chem.Lett_11_2627
PubMedID: 11551765

Title : Preferential cerebrospinal fluid acetylcholinesterase inhibition by rivastigmine in humans - Kennedy_1999_J.Clin.Psychopharmacol_19_513
Author(s) : Kennedy JS , Polinsky RJ , Johnson B , Loosen P , Enz A , Laplanche R , Schmidt D , Mancione LC , Parris WC , Ebert MH
Ref : J Clin Psychopharmacol , 19 :513 , 1999
Abstract : Kennedy_1999_J.Clin.Psychopharmacol_19_513
ESTHER : Kennedy_1999_J.Clin.Psychopharmacol_19_513
PubMedSearch : Kennedy_1999_J.Clin.Psychopharmacol_19_513
PubMedID: 10587286

Title : Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease - Cutler_1998_Acta.Neurol.Scand_97_244
Author(s) : Cutler NR , Polinsky RJ , Sramek JJ , Enz A , Jhee SS , Mancione L , Hourani J , Zolnouni P
Ref : Acta Neurologica Scandinavica , 97 :244 , 1998
Abstract : Cutler_1998_Acta.Neurol.Scand_97_244
ESTHER : Cutler_1998_Acta.Neurol.Scand_97_244
PubMedSearch : Cutler_1998_Acta.Neurol.Scand_97_244
PubMedID: 9576639

Title : Kinetic and structural studies on the interaction of the anti-Alzheimer drug, ENA-713, with Torpedo californica acetylcholinesterase -
Author(s) : Bar-On P , Harel M , Millard CB , Enz A , Sussman JL , Silman I
Ref : Journal de Physiologie (Paris) , 92 :406 , 1998
PubMedID:

Title : Kinetic and X-Ray Crystallographic Studies of the Binding of ENA-713 to Torpedo Californica Acetylcholinesterase -
Author(s) : Bar-On P , Harel M , Millard CB , Enz A , Sussman JL , Silman I
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :373 , 1998
PubMedID:

Title : Acetylcholinesterase Inhibitors (AChE-I) as a Potential Use for Alzheimers Disease (AD) Therapy -
Author(s) : Enz A
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :475 , 1995
PubMedID:

Title : Pharmacological evaluation of phenyl-carbamates as CNS-selective acetylcholinesterase inhibitors - Weinstock_1994_J.Neural.Transm.Suppl_43_219
Author(s) : Weinstock M , Razin M , Chorev M , Enz A
Ref : J Neural Transm Suppl , 43 :219 , 1994
Abstract : Weinstock_1994_J.Neural.Transm.Suppl_43_219
ESTHER : Weinstock_1994_J.Neural.Transm.Suppl_43_219
PubMedSearch : Weinstock_1994_J.Neural.Transm.Suppl_43_219
PubMedID: 7884403

Title : Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease - Enz_1993_Prog.Brain.Res_98_431
Author(s) : Enz A , Amstutz R , Boddeke H , Gmelin G , Malanowski J , Boddeke HW
Ref : Prog Brain Res , 98 :431 , 1993
Abstract : Enz_1993_Prog.Brain.Res_98_431
ESTHER : Enz_1993_Prog.Brain.Res_98_431
PubMedSearch : Enz_1993_Prog.Brain.Res_98_431
PubMedID: 8248533

Title : SDZ ENS 163 a novel pilocarpine like drug: pharmacological in vitro and in vivo profile - Enz_1993_Life.Sci_52(5-6)_513
Author(s) : Enz A , Boddeke HW , Sauter A , Rudin M , Shapiro G
Ref : Life Sciences , 52 :513 , 1993
Abstract : Enz_1993_Life.Sci_52(5-6)_513
ESTHER : Enz_1993_Life.Sci_52(5-6)_513
PubMedSearch : Enz_1993_Life.Sci_52(5-6)_513
PubMedID: 8382766

Title : M1 muscarinic receptors mediate intracellular calcium release in NB-OK1 human neuroblastoma cells - Boddeke_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_346_255
Author(s) : Boddeke HW , Buttini M , Lichtsteiner M , Enz A
Ref : Naunyn Schmiedebergs Arch Pharmacol , 346 :255 , 1992
Abstract : Boddeke_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_346_255
ESTHER : Boddeke_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_346_255
PubMedSearch : Boddeke_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_346_255
PubMedID: 1407011

Title : Different Influence of Inhibitors on Acetylcholinesterase Molecular forms G1 and G4 Isolated from Alzheimers Disease and Control Brains -
Author(s) : Enz A , Chappuis A , Probst A
Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :243 , 1992
PubMedID:

Title : SDZ ENS 163 is a selective M1 agonist and induces release of acetylcholine - Enz_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_345_282
Author(s) : Enz A , Shapiro G , Supavilai P , Boddeke HW
Ref : Naunyn Schmiedebergs Arch Pharmacol , 345 :282 , 1992
Abstract : Enz_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_345_282
ESTHER : Enz_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_345_282
PubMedSearch : Enz_1992_Naunyn.Schmiedebergs.Arch.Pharmacol_345_282
PubMedID: 1620233

Title : Pharmacologic and clinicopharmacologic properties of SDZ ENA 713, a centrally selective acetylcholinesterase inhibitor -
Author(s) : Enz A , Boddeke H , Gray J , Spiegel R
Ref : Annals of the New York Academy of Sciences , 640 :272 , 1991
PubMedID: 1776750

Title : Poster: Muscarinic agonists for senile dementia, past experience and future trends -
Author(s) : Gray JA , Enz A , Spiegel R
Ref : Trends in Pharmacological Sciences , Suppl :98 , 1989
PubMedID:

Title : Muscarinic agonists for senile dementia: past experience and future trends - Gray_1989_Trends.Pharmacol.Sci_Suppl_85
Author(s) : Gray JA , Enz A , Spiegel R
Ref : Trends in Pharmacological Sciences , Suppl :85 , 1989
Abstract : Gray_1989_Trends.Pharmacol.Sci_Suppl_85
ESTHER : Gray_1989_Trends.Pharmacol.Sci_Suppl_85
PubMedSearch : Gray_1989_Trends.Pharmacol.Sci_Suppl_85
PubMedID: 2694530