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References (21)

Title : Extracellular alpha\/beta-hydrolase from Paenibacillus species shares structural and functional homology to Tobacco Salicylic Acid Binding Protein 2 - Wilkinson_2020_J.Struct.Biol__107496
Author(s) : Wilkinson RC , Rahman Pour R , Jamshidi S , Fulop V , Bugg TDH
Ref : J Struct Biol , :107496 , 2020
Abstract : Wilkinson_2020_J.Struct.Biol__107496
ESTHER : Wilkinson_2020_J.Struct.Biol__107496
PubMedSearch : Wilkinson_2020_J.Struct.Biol__107496
PubMedID: 32224091
Gene_locus related to this paper: 9bacl-a0a1r0zp85

Title : Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling - Rea_2017_Eur.J.Med.Chem_139_482
Author(s) : Rea D , Van Elzen R , De Winter H , Van Goethem S , Landuyt B , Luyten W , Schoofs L , Van der Veken P , Augustyns K , De Meester I , Fulop V , Lambeir AM
Ref : Eur Journal of Medicinal Chemistry , 139 :482 , 2017
Abstract : Rea_2017_Eur.J.Med.Chem_139_482
ESTHER : Rea_2017_Eur.J.Med.Chem_139_482
PubMedSearch : Rea_2017_Eur.J.Med.Chem_139_482
PubMedID: 28826083
Gene_locus related to this paper: porgi-DPP

Title : Crystal structures of Trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymes - Canning_2013_PLoS.One_8_e79349
Author(s) : Canning P , Rea D , Morty RE , Fulop V
Ref : PLoS ONE , 8 :e79349 , 2013
Abstract : Canning_2013_PLoS.One_8_e79349
ESTHER : Canning_2013_PLoS.One_8_e79349
PubMedSearch : Canning_2013_PLoS.One_8_e79349
PubMedID: 24265767
Gene_locus related to this paper: trybr-PEPTB

Title : P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy - Van der Veken_2012_J.Med.Chem_55_9856
Author(s) : Van der Veken P , Fulop V , Rea D , Gerard M , Van Elzen R , Joossens J , Cheng JD , Baekelandt V , De Meester I , Lambeir AM , Augustyns K
Ref : Journal of Medicinal Chemistry , 55 :9856 , 2012
Abstract : Van der Veken_2012_J.Med.Chem_55_9856
ESTHER : Van der Veken_2012_J.Med.Chem_55_9856
PubMedSearch : Van der Veken_2012_J.Med.Chem_55_9856
PubMedID: 23121075
Gene_locus related to this paper: pig-ppce

Title : Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase. - Kaszuba_2012_Biochimie_94_1398
Author(s) : Kaszuba K , Rog T , Danne R , Canning P , Fulop V , Juhasz T , Szeltner Z , St Pierre JF , Garcia-Horsman A , Mannisto PT , Karttunen M , Hokkanen J , Bunker A
Ref : Biochimie , 94 :1398 , 2012
Abstract : Kaszuba_2012_Biochimie_94_1398
ESTHER : Kaszuba_2012_Biochimie_94_1398
PubMedSearch : Kaszuba_2012_Biochimie_94_1398
PubMedID: 22484394
Gene_locus related to this paper: pig-ppce

Title : The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity - Szeltner_2012_Biochim.Biophys.Acta_1834_98
Author(s) : Szeltner Z , Juhasz T , Szamosi I , Rea D , Fulop V , Modos K , Juliano L , Polgar L
Ref : Biochimica & Biophysica Acta , 1834 :98 , 2012
Abstract : Szeltner_2012_Biochim.Biophys.Acta_1834_98
ESTHER : Szeltner_2012_Biochim.Biophys.Acta_1834_98
PubMedSearch : Szeltner_2012_Biochim.Biophys.Acta_1834_98
PubMedID: 22940581
Gene_locus related to this paper: pig-ppce

Title : Prolyl oligopeptidase structure and dynamics - Rea_2011_CNS.Neurol.Disord.Drug.Targets_10_306
Author(s) : Rea D , Fulop V
Ref : CNS Neurol Disord Drug Targets , 10 :306 , 2011
Abstract : Rea_2011_CNS.Neurol.Disord.Drug.Targets_10_306
ESTHER : Rea_2011_CNS.Neurol.Disord.Drug.Targets_10_306
PubMedSearch : Rea_2011_CNS.Neurol.Disord.Drug.Targets_10_306
PubMedID: 21222626

Title : Inhibition of prolyl oligopeptidase with a synthetic unnatural dipeptide - Racys_2010_Bioorg.Med.Chem_18_4775
Author(s) : Racys DT , Rea D , Fulop V , Wills M
Ref : Bioorganic & Medicinal Chemistry , 18 :4775 , 2010
Abstract : Racys_2010_Bioorg.Med.Chem_18_4775
ESTHER : Racys_2010_Bioorg.Med.Chem_18_4775
PubMedSearch : Racys_2010_Bioorg.Med.Chem_18_4775
PubMedID: 20627594
Gene_locus related to this paper: pig-ppce

Title : Structure-function properties of prolyl oligopeptidase family enzymes - Rea_2006_Cell.Biochem.Biophys_44_349
Author(s) : Rea D , Fulop V
Ref : Cell Biochem Biophys , 44 :349 , 2006
Abstract : Rea_2006_Cell.Biochem.Biophys_44_349
ESTHER : Rea_2006_Cell.Biochem.Biophys_44_349
PubMedSearch : Rea_2006_Cell.Biochem.Biophys_44_349
PubMedID: 16679522

Title : Crystallization and preliminary crystallographic analysis of porcine acylaminoacyl peptidase - Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
Author(s) : Wright H , Kiss AL , Szeltner Z , Polgar L , Fulop V
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 61 :942 , 2005
Abstract : Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
ESTHER : Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
PubMedSearch : Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942
PubMedID: 16511202
Gene_locus related to this paper: aerpe-APE1547

Title : Unclosed beta-propellers display stable structures: implications for substrate access to the active site of prolyl oligopeptidase - Juhasz_2005_J.Mol.Biol_346_907
Author(s) : Juhasz T , Szeltner Z , Fulop V , Polgar L
Ref : Journal of Molecular Biology , 346 :907 , 2005
Abstract : Juhasz_2005_J.Mol.Biol_346_907
ESTHER : Juhasz_2005_J.Mol.Biol_346_907
PubMedSearch : Juhasz_2005_J.Mol.Biol_346_907
PubMedID: 15713471

Title : Expression, purification and preliminary crystallographic analysis of dipeptidyl peptidase IV from Porphyromonas gingivalis - Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871
Author(s) : Rea D , Lambeir AM , Kumagai Y , De Meester I , Scharpe S , Fulop V
Ref : Acta Crystallographica D Biol Crystallogr , 60 :1871 , 2004
Abstract : Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871
ESTHER : Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871
PubMedSearch : Rea_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1871
PubMedID: 15388936
Gene_locus related to this paper: porgi-DPP

Title : Concerted structural changes in the peptidase and the propeller domains of prolyl oligopeptidase are required for substrate binding - Szeltner_2004_J.Mol.Biol_340_627
Author(s) : Szeltner Z , Rea D , Juhasz T , Renner V , Fulop V , Polgar L
Ref : Journal of Molecular Biology , 340 :627 , 2004
Abstract : Szeltner_2004_J.Mol.Biol_340_627
ESTHER : Szeltner_2004_J.Mol.Biol_340_627
PubMedSearch : Szeltner_2004_J.Mol.Biol_340_627
PubMedID: 15210359
Gene_locus related to this paper: pig-q6q2c2

Title : Exploration of the active site of dipeptidyl peptidase IV from Porphyromonas gingivalis. Comparison with the human enzyme -
Author(s) : Lambeir AM , Rea D , Fulop V , Kumagai Y , Augustyns K , De Meester I , Haemers A , Scharpe S
Ref : Advances in Experimental Medicine & Biology , 524 :29 , 2003
PubMedID: 12675220

Title : Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate binding - Szeltner_2003_J.Biol.Chem_278_48786
Author(s) : Szeltner Z , Rea D , Renner V , Juliano L , Fulop V , Polgar L
Ref : Journal of Biological Chemistry , 278 :48786 , 2003
Abstract : Szeltner_2003_J.Biol.Chem_278_48786
ESTHER : Szeltner_2003_J.Biol.Chem_278_48786
PubMedSearch : Szeltner_2003_J.Biol.Chem_278_48786
PubMedID: 14514675
Gene_locus related to this paper: pig-ppce

Title : Substrate recognition properties of oligopeptidase B from Salmonella enterica serovar Typhimurium - Morty_2002_J.Bacteriol_184_3329
Author(s) : Morty RE , Fulop V , Andrews NW
Ref : Journal of Bacteriology , 184 :3329 , 2002
Abstract : Morty_2002_J.Bacteriol_184_3329
ESTHER : Morty_2002_J.Bacteriol_184_3329
PubMedSearch : Morty_2002_J.Bacteriol_184_3329
PubMedID: 12029050
Gene_locus related to this paper: salen-OPDB

Title : Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site - Szeltner_2002_J.Biol.Chem_277_42613
Author(s) : Szeltner Z , Rea D , Renner V , Fulop V , Polgar L
Ref : Journal of Biological Chemistry , 277 :42613 , 2002
Abstract : Szeltner_2002_J.Biol.Chem_277_42613
ESTHER : Szeltner_2002_J.Biol.Chem_277_42613
PubMedSearch : Szeltner_2002_J.Biol.Chem_277_42613
PubMedID: 12202494
Gene_locus related to this paper: pig-ppce

Title : Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase - Szeltner_2002_J.Biol.Chem_277_44597
Author(s) : Szeltner Z , Rea D , Juhasz T , Renner V , Mucsi Z , Orosz G , Fulop V , Polgar L
Ref : Journal of Biological Chemistry , 277 :44597 , 2002
Abstract : Szeltner_2002_J.Biol.Chem_277_44597
ESTHER : Szeltner_2002_J.Biol.Chem_277_44597
PubMedSearch : Szeltner_2002_J.Biol.Chem_277_44597
PubMedID: 12228249
Gene_locus related to this paper: pig-ppce

Title : Structures of prolyl oligopeptidase substrate\/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue - Fulop_2001_J.Biol.Chem_276_1262
Author(s) : Fulop V , Szeltner Z , Renner V , Polgar L
Ref : Journal of Biological Chemistry , 276 :1262 , 2001
Abstract : Fulop_2001_J.Biol.Chem_276_1262
ESTHER : Fulop_2001_J.Biol.Chem_276_1262
PubMedSearch : Fulop_2001_J.Biol.Chem_276_1262
PubMedID: 11031266
Gene_locus related to this paper: pig-ppce

Title : Catalysis of serine oligopeptidases is controlled by a gating filter mechanism - Fulop_2000_EMBO.Rep_1_277
Author(s) : Fulop V , Szeltner Z , Polgar L
Ref : EMBO Rep , 1 :277 , 2000
Abstract : Fulop_2000_EMBO.Rep_1_277
ESTHER : Fulop_2000_EMBO.Rep_1_277
PubMedSearch : Fulop_2000_EMBO.Rep_1_277
PubMedID: 11256612
Gene_locus related to this paper: pig-ppce

Title : Prolyl oligopeptidase: an unusual beta-propeller domain regulates proteolysis - Fulop_1998_Cell_94_161
Author(s) : Fulop V , Bocskei Z , Polgar L
Ref : Cell , 94 :161 , 1998
Abstract : Fulop_1998_Cell_94_161
ESTHER : Fulop_1998_Cell_94_161
PubMedSearch : Fulop_1998_Cell_94_161
PubMedID: 9695945
Gene_locus related to this paper: pig-ppce