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| Title : Smaller quantal size and faster kinetics of single exocytotic events in chromaffin cells from the APP\/PS1 mouse model of Alzheimer's disease - de Diego_2012_Biochem.Biophys.Res.Commun_428_482 |
| Author(s) : de Diego AM , Lorrio S , Calvo-Gallardo E , Garcia AG |
| Ref : Biochemical & Biophysical Research Communications , 428 :482 , 2012 |
| Abstract : de Diego_2012_Biochem.Biophys.Res.Commun_428_482 |
| ESTHER : de Diego_2012_Biochem.Biophys.Res.Commun_428_482 |
| PubMedSearch : de Diego_2012_Biochem.Biophys.Res.Commun_428_482 |
| PubMedID: 23123627 |
| Title : Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity - Pereira_2011_Eur.J.Pharmacol_660_411 |
| Author(s) : Pereira JD , Caricati-Neto A , Miranda-Ferreira R , Smaili SS , Godinho RO , de los Rios C , Leon R , Villaroya M , Samadi A , Marco-Contelles J , Jurkiewicz NH , Garcia AG , Jurkiewicz A |
| Ref : European Journal of Pharmacology , 660 :411 , 2011 |
| Abstract : Pereira_2011_Eur.J.Pharmacol_660_411 |
| ESTHER : Pereira_2011_Eur.J.Pharmacol_660_411 |
| PubMedSearch : Pereira_2011_Eur.J.Pharmacol_660_411 |
| PubMedID: 21497158 |
| Title : N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease - Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Romero A , Del Barrio L , Martin-de-Saavedra MD , Egea J , Leon R , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 46 :2224 , 2011 |
| Abstract : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| ESTHER : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| PubMedSearch : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224 |
| PubMedID: 21420206 |
| Title : Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles - Samadi_2010_Bioorg.Med.Chem_18_5861 |
| Author(s) : Samadi A , Marco-Contelles J , Soriano E , Alvarez-Perez M , Chioua M , Romero A , Gonzalez-Lafuente L , Gandia L , Roda JM , Lopez MG , Villarroya M , Garcia AG , Rios Cde L |
| Ref : Bioorganic & Medicinal Chemistry , 18 :5861 , 2010 |
| Abstract : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| ESTHER : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| PubMedSearch : Samadi_2010_Bioorg.Med.Chem_18_5861 |
| PubMedID: 20656495 |
| Title : Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives - de Los Rios_2010_J.Med.Chem_53_5129 |
| Author(s) : de los Rios C , Egea J , Marco-Contelles J , Leon R , Samadi A , Iriepa I , Moraleda I , Galvez E , Garcia AG , Lopez MG , Villarroya M , Romero A |
| Ref : Journal of Medicinal Chemistry , 53 :5129 , 2010 |
| Abstract : de Los Rios_2010_J.Med.Chem_53_5129 |
| ESTHER : de Los Rios_2010_J.Med.Chem_53_5129 |
| PubMedSearch : de Los Rios_2010_J.Med.Chem_53_5129 |
| PubMedID: 20575555 |
| Title : Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties - Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| Author(s) : Fernandez-Bachiller MI , Perez C , Gonzalez-Munoz GC , Conde S , Lopez MG , Villarroya M , Garcia AG , Rodriguez-Franco MI |
| Ref : Journal of Medicinal Chemistry , 53 :4927 , 2010 |
| Abstract : Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| ESTHER : Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| PubMedSearch : Fernandez-Bachiller_2010_J.Med.Chem_53_4927 |
| PubMedID: 20545360 |
| Title : Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells - Romero_2010_J.Pineal.Res_49_141 |
| Author(s) : Romero A , Egea J , Garcia AG , Lopez MG |
| Ref : J Pineal Res , 49 :141 , 2010 |
| Abstract : Romero_2010_J.Pineal.Res_49_141 |
| ESTHER : Romero_2010_J.Pineal.Res_49_141 |
| PubMedSearch : Romero_2010_J.Pineal.Res_49_141 |
| PubMedID: 20536682 |
| Title : Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases - Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI |
| Ref : Eur Journal of Medicinal Chemistry , 45 :6152 , 2010 |
| Abstract : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| ESTHER : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| PubMedSearch : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152 |
| PubMedID: 20926162 |
| Title : Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties - Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| Author(s) : Fernandez-Bachiller MI , Perez C , Campillo NE , Paez JA , Gonzalez-Munoz GC , Usan P , Garcia-Palomero E , Lopez MG , Villarroya M , Garcia AG , Martinez A , Rodriguez-Franco MI |
| Ref : ChemMedChem , 4 :828 , 2009 |
| Abstract : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| ESTHER : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| PubMedSearch : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
| PubMedID: 19308922 |
| Title : Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils - Lorrio_2009_Brain.Res_1254_128 |
| Author(s) : Lorrio S , Negredo P , Roda JM , Garcia AG , Lopez MG |
| Ref : Brain Research , 1254 :128 , 2009 |
| Abstract : Lorrio_2009_Brain.Res_1254_128 |
| ESTHER : Lorrio_2009_Brain.Res_1254_128 |
| PubMedSearch : Lorrio_2009_Brain.Res_1254_128 |
| PubMedID: 19103181 |
| Title : Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease - Arce_2009_J.Med.Chem_52_7249 |
| Author(s) : Arce MP , Rodriguez-Franco MI , Gonzalez-Munoz GC , Perez C , Lopez B , Villarroya M , Lopez MG , Garcia AG , Conde S |
| Ref : Journal of Medicinal Chemistry , 52 :7249 , 2009 |
| Abstract : Arce_2009_J.Med.Chem_52_7249 |
| ESTHER : Arce_2009_J.Med.Chem_52_7249 |
| PubMedSearch : Arce_2009_J.Med.Chem_52_7249 |
| PubMedID: 19856923 |
| Title : New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties - Leon_2008_Bioorg.Med.Chem_16_7759 |
| Author(s) : Leon R , de los Rios C , Marco-Contelles J , Huertas O , Barril X , Luque FJ , Lopez MG , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 16 :7759 , 2008 |
| Abstract : Leon_2008_Bioorg.Med.Chem_16_7759 |
| ESTHER : Leon_2008_Bioorg.Med.Chem_16_7759 |
| PubMedSearch : Leon_2008_Bioorg.Med.Chem_16_7759 |
| PubMedID: 18640842 |
| Title : An update on the pharmacology of galantamine - Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| Author(s) : Villarroya M , Garcia AG , Marco-Contelles J , Lopez MG |
| Ref : Expert Opin Investig Drugs , 16 :1987 , 2007 |
| Abstract : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| ESTHER : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| PubMedSearch : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987 |
| PubMedID: 18042006 |
| Title : Desensitized nicotinic receptors that, however, afford cytoprotection in bovine chromaffin cells - Egea_2006_J.Mol.Neurosci_30_59 |
| Author(s) : Egea J , Hernandez-Guijo JM , Olivares R , Lopez MG , Garcia AG |
| Ref : Journal of Molecular Neuroscience , 30 :59 , 2006 |
| Abstract : Egea_2006_J.Mol.Neurosci_30_59 |
| ESTHER : Egea_2006_J.Mol.Neurosci_30_59 |
| PubMedSearch : Egea_2006_J.Mol.Neurosci_30_59 |
| PubMedID: 17192627 |
| Title : Can cholinesterase inhibitors provide additional effects to cholinergic neurotransmission enhancement? - Lopez_2006_J.Mol.Neurosci_30_141 |
| Author(s) : Lopez MG , Arias E , Sobrado M , Lorrio S , Roda JM , Garcia AG |
| Ref : Journal of Molecular Neuroscience , 30 :141 , 2006 |
| Abstract : Lopez_2006_J.Mol.Neurosci_30_141 |
| ESTHER : Lopez_2006_J.Mol.Neurosci_30_141 |
| PubMedSearch : Lopez_2006_J.Mol.Neurosci_30_141 |
| PubMedID: 17192661 |
| Title : A comparison between acetylcholine-like action potentials and square depolarizing pulses in triggering calcium entry and exocytosis in bovine chromaffin cells - Garcia_2006_J.Mol.Neurosci_30_57 |
| Author(s) : Garcia de Diego AM , Arnaiz JJ , Gandia L , Hernandez-Guijo JM , Garcia AG |
| Ref : Journal of Molecular Neuroscience , 30 :57 , 2006 |
| Abstract : Garcia_2006_J.Mol.Neurosci_30_57 |
| ESTHER : Garcia_2006_J.Mol.Neurosci_30_57 |
| PubMedSearch : Garcia_2006_J.Mol.Neurosci_30_57 |
| PubMedID: 17192626 |
| Title : Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease - Marco-Contelles_2006_J.Med.Chem_49_7607 |
| Author(s) : Marco-Contelles J , Leon R , de los Rios C , Guglietta A , Terencio J , Lopez MG , Garcia AG , Villarroya M |
| Ref : Journal of Medicinal Chemistry , 49 :7607 , 2006 |
| Abstract : Marco-Contelles_2006_J.Med.Chem_49_7607 |
| ESTHER : Marco-Contelles_2006_J.Med.Chem_49_7607 |
| PubMedSearch : Marco-Contelles_2006_J.Med.Chem_49_7607 |
| PubMedID: 17181144 |
| Title : Neuroprotection by nicotine in hippocampal slices subjected to oxygen-glucose deprivation: involvement of the alpha7 nAChR subtype - Rosa_2006_J.Mol.Neurosci_30_61 |
| Author(s) : Rosa AO , Egea J , Gandia L , Lopez MG , Garcia AG |
| Ref : Journal of Molecular Neuroscience , 30 :61 , 2006 |
| Abstract : Rosa_2006_J.Mol.Neurosci_30_61 |
| ESTHER : Rosa_2006_J.Mol.Neurosci_30_61 |
| PubMedSearch : Rosa_2006_J.Mol.Neurosci_30_61 |
| PubMedID: 17192628 |
| Title : Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals - Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| Author(s) : Marco-Contelles J , Leon R , Lopez MG , Garcia AG , Villarroya M |
| Ref : Eur Journal of Medicinal Chemistry , 41 :1464 , 2006 |
| Abstract : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| ESTHER : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| PubMedSearch : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464 |
| PubMedID: 17030484 |
| Title : Blockade of Ca2+ -activated K+ channels by galantamine can also contribute to the potentiation of catecholamine secretion from chromaffin cells - Ales_2006_Eur.J.Pharmacol_548_45 |
| Author(s) : Ales E , Gullo F , Arias E , Olivares R , Garcia AG , Wanke E , Lopez MG |
| Ref : European Journal of Pharmacology , 548 :45 , 2006 |
| Abstract : Ales_2006_Eur.J.Pharmacol_548_45 |
| ESTHER : Ales_2006_Eur.J.Pharmacol_548_45 |
| PubMedSearch : Ales_2006_Eur.J.Pharmacol_548_45 |
| PubMedID: 16949070 |
| Title : Enhancement of secretion by threshold nicotinic stimulation in bovine chromaffin cells - Tapia_2006_J.Mol.Neurosci_30_81 |
| Author(s) : Tapia L , Eguiagaray JG , Egea J , Garcia AG , Gandia L |
| Ref : Journal of Molecular Neuroscience , 30 :81 , 2006 |
| Abstract : Tapia_2006_J.Mol.Neurosci_30_81 |
| ESTHER : Tapia_2006_J.Mol.Neurosci_30_81 |
| PubMedSearch : Tapia_2006_J.Mol.Neurosci_30_81 |
| PubMedID: 17192638 |
| Title : Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors - Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| Author(s) : Arias E , Gallego-Sandin S , Villarroya M , Garcia AG , Lopez MG |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 315 :1346 , 2005 |
| Abstract : Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| ESTHER : Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| PubMedSearch : Arias_2005_J.Pharmacol.Exp.Ther_315_1346 |
| PubMedID: 16144975 |
| Title : Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues - Leon_2005_Bioorg.Med.Chem_13_1167 |
| Author(s) : Leon R , Marco-Contelles J , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 13 :1167 , 2005 |
| Abstract : Leon_2005_Bioorg.Med.Chem_13_1167 |
| ESTHER : Leon_2005_Bioorg.Med.Chem_13_1167 |
| PubMedSearch : Leon_2005_Bioorg.Med.Chem_13_1167 |
| PubMedID: 15670925 |
| Title : Enhancement of purinergic neurotransmission by galantamine and other acetylcholinesterase inhibitors in the rat vas deferens - Caricati-Neto_2004_Eur.J.Pharmacol_503_191 |
| Author(s) : Caricati-Neto A , D'Angelo L C , Reuter H , Hyppolito Jurkiewicz N , Garcia AG , Jurkiewicz A |
| Ref : European Journal of Pharmacology , 503 :191 , 2004 |
| Abstract : Caricati-Neto_2004_Eur.J.Pharmacol_503_191 |
| ESTHER : Caricati-Neto_2004_Eur.J.Pharmacol_503_191 |
| PubMedSearch : Caricati-Neto_2004_Eur.J.Pharmacol_503_191 |
| PubMedID: 15496314 |
| Title : Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase\/butyrylcholinesterase and modulators of Ca2+ channels and nicotinic receptors - Marco_2004_Bioorg.Med.Chem_12_2199 |
| Author(s) : Marco JL , de los Rios C , Garcia AG , Villarroya M , Carreiras MC , Martins C , Eleuterio A , Morreale A , Orozco M , Luque FJ |
| Ref : Bioorganic & Medicinal Chemistry , 12 :2199 , 2004 |
| Abstract : Marco_2004_Bioorg.Med.Chem_12_2199 |
| ESTHER : Marco_2004_Bioorg.Med.Chem_12_2199 |
| PubMedSearch : Marco_2004_Bioorg.Med.Chem_12_2199 |
| PubMedID: 15080920 |
| Title : Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation - Sobrado_2004_Neurosci.Lett_365_132 |
| Author(s) : Sobrado M , Roda JM , Lopez MG , Egea J , Garcia AG |
| Ref : Neuroscience Letters , 365 :132 , 2004 |
| Abstract : Sobrado_2004_Neurosci.Lett_365_132 |
| ESTHER : Sobrado_2004_Neurosci.Lett_365_132 |
| PubMedSearch : Sobrado_2004_Neurosci.Lett_365_132 |
| PubMedID: 15245794 |
| Title : New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer's disease - Villarroya_2004_Curr.Pharm.Des_10_3177 |
| Author(s) : Villarroya M , Garcia AG , Marco JL |
| Ref : Curr Pharm Des , 10 :3177 , 2004 |
| Abstract : Villarroya_2004_Curr.Pharm.Des_10_3177 |
| ESTHER : Villarroya_2004_Curr.Pharm.Des_10_3177 |
| PubMedSearch : Villarroya_2004_Curr.Pharm.Des_10_3177 |
| PubMedID: 15544507 |
| Title : Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors - Arias_2004_Neuropharmacol_46_103 |
| Author(s) : Arias E , Ales E , Gabilan NH , Cano-Abad MF , Villarroya M , Garcia AG , Lopez MG |
| Ref : Neuropharmacology , 46 :103 , 2004 |
| Abstract : Arias_2004_Neuropharmacol_46_103 |
| ESTHER : Arias_2004_Neuropharmacol_46_103 |
| PubMedSearch : Arias_2004_Neuropharmacol_46_103 |
| PubMedID: 14654102 |
| Title : ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylat e), a novel acetylcholinesterase inhibitor with calcium promotor and neuroprotective properties - Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| Author(s) : Orozco C , de los Rios C , Arias E , Leon R , Garcia AG , Marco JL , Villarroya M , Lopez MG |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :987 , 2004 |
| Abstract : Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| ESTHER : Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| PubMedSearch : Orozco_2004_J.Pharmacol.Exp.Ther_310_987 |
| PubMedID: 15111641 |
| Title : Novel tacrine derivatives that block neuronal calcium channels - de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| Author(s) : de los Rios C , Marco JL , Carreiras MD , Chinchon PM , Garcia AG , Villarroya M |
| Ref : Bioorganic & Medicinal Chemistry , 10 :2077 , 2002 |
| Abstract : de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| ESTHER : de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| PubMedSearch : de los Rios_2002_Bioorg.Med.Chem_10_2077 |
| PubMedID: 11937366 |
| Title : [Treatment of mild cognitive impairment: value of citicoline] - Abad_2002_Rev.Neurol_35_675 |
| Author(s) : Abad Santos F , Novalbos J , Gallego Sandin S , Garcia AG |
| Ref : Rev Neurol , 35 :675 , 2002 |
| Abstract : Abad_2002_Rev.Neurol_35_675 |
| ESTHER : Abad_2002_Rev.Neurol_35_675 |
| PubMedSearch : Abad_2002_Rev.Neurol_35_675 |
| PubMedID: 12389156 |