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Title : Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV - Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
Author(s) : Namoto K , Sirockin F , Ostermann N , Gessier F , Flohr S , Sedrani R , Gerhartz B , Trappe J , Hassiepen U , Duttaroy A , Ferreira S , Sutton JM , Clark DE , Fenton G , Beswick M , Baeschlin DK |
Ref : Bioorganic & Medicinal Chemistry Lett , 24 :731 , 2014 |
Abstract : Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
ESTHER : Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
PubMedSearch : Namoto_2014_Bioorg.Med.Chem.Lett_24_731 |
PubMedID: 24439847 |
Gene_locus related to this paper: human-DPP4 |
Title : Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. - Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
Author(s) : Sutton JM , Clark DE , Dunsdon SJ , Fenton G , Fillmore A , Harris NV , Higgs C , Hurley CA , Krintel SL , Mackenzie RE , Duttaroy A , Gangl E , Maniara W , Sedrani R , Namoto K , Ostermann N , Gerhartz B , Sirockin F , Trappe J , Hassiepen U , Baeschlin DK |
Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1464 , 2012 |
Abstract : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
ESTHER : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
PubMedSearch : Sutton_2012_Bioorg.Med.Chem.Lett_22_1464 |
PubMedID: 22177783 |
Gene_locus related to this paper: human-DPP4 |
Title : Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion - Schulz_2005_J.Neurochem_94_970 |
Author(s) : Schulz I , Zeitschel U , Rudolph T , Ruiz-Carrillo D , Rahfeld JU , Gerhartz B , Bigl V , Demuth HU , Rossner S |
Ref : Journal of Neurochemistry , 94 :970 , 2005 |
Abstract : Schulz_2005_J.Neurochem_94_970 |
ESTHER : Schulz_2005_J.Neurochem_94_970 |
PubMedSearch : Schulz_2005_J.Neurochem_94_970 |
PubMedID: 16092940 |
Title : Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme - Bar_2003_Biol.Chem_384_1553 |
Author(s) : Bar J , Weber A , Hoffmann T , Stork J , Wermann M , Wagner L , Aust S , Gerhartz B , Demuth HU |
Ref : Biol Chem , 384 :1553 , 2003 |
Abstract : Bar_2003_Biol.Chem_384_1553 |
ESTHER : Bar_2003_Biol.Chem_384_1553 |
PubMedSearch : Bar_2003_Biol.Chem_384_1553 |
PubMedID: 14719797 |