Full name : Gorecki Lukas
First name : Lukas
Mail : Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove
Zip Code :
City :
Country : Czech Republic
Email : gorecluk@fnhk.cz
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Directory :
| Title : Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication - Gorecki_2024_Chem.Biol.Interact__110941 |
| Author(s) : Gorecki L , Markova A , Hepnarova V , Zivna N , Junova L , Hrabinova M , Janousek J , Kobrlova T , Prchal L , Jun D , Soukup O , Horn G , Worek F , Marek J , Korabecny J |
| Ref : Chemico-Biological Interactions , :110941 , 2024 |
| Abstract : Gorecki_2024_Chem.Biol.Interact__110941 |
| ESTHER : Gorecki_2024_Chem.Biol.Interact__110941 |
| PubMedSearch : Gorecki_2024_Chem.Biol.Interact__110941 |
| PubMedID: 38493910 |
| Title : Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides - Hepnarova_2022_Toxicol.In.Vitro__105463 |
| Author(s) : Hepnarova V , Hrabinova M , Muckova L , Kucera T , Schmidt M , Dolezal R , Gorecki L , Hrabcova V , Korabecny J , Mezeiova E , Jun D , Pejchal J |
| Ref : Toxicol In Vitro , :105463 , 2022 |
| Abstract : Hepnarova_2022_Toxicol.In.Vitro__105463 |
| ESTHER : Hepnarova_2022_Toxicol.In.Vitro__105463 |
| PubMedSearch : Hepnarova_2022_Toxicol.In.Vitro__105463 |
| PubMedID: 36041654 |
| Title : Countermeasures in organophosphorus intoxication: pitfalls and prospects - Gorecki_2022_Trends.Pharmacol.Sci__ |
| Author(s) : Gorecki L , Soukup O , Korabecny J |
| Ref : Trends in Pharmacological Sciences , : , 2022 |
| Abstract : Gorecki_2022_Trends.Pharmacol.Sci__ |
| ESTHER : Gorecki_2022_Trends.Pharmacol.Sci__ |
| PubMedSearch : Gorecki_2022_Trends.Pharmacol.Sci__ |
| PubMedID: 35643835 |
| Title : Huprine Y - tryptophan heterodimers with potential implication to Alzheimer's disease treatment - Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| Author(s) : Mezeiova E , Hrabinova M , Hepnarova V , Jun D , Janockova J , Muckova L , Prchal L , Kristofikova Z , Kucera T , Gorecki L , Chalupova K , Kunes J , Hroudova J , Soukup O , Korabecny J |
| Ref : Bioorganic & Medicinal Chemistry Lett , :128100 , 2021 |
| Abstract : Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| ESTHER : Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| PubMedSearch : Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 |
| PubMedID: 33984470 |
| Title : Development of versatile and potent monoquaternary reactivators of acetylcholinesterase - Gorecki_2021_Arch.Toxicol__ |
| Author(s) : Gorecki L , Hepnarova V , Karasova JZ , Hrabinova M , Courageux C , Dias J , Kucera T , Kobrlova T , Muckova L , Prchal L , Malinak D , Jun D , Musilek K , Worek F , Nachon F , Soukup O , Korabecny J |
| Ref : Archives of Toxicology , : , 2021 |
| Abstract : Gorecki_2021_Arch.Toxicol__ |
| ESTHER : Gorecki_2021_Arch.Toxicol__ |
| PubMedSearch : Gorecki_2021_Arch.Toxicol__ |
| PubMedID: 33517499 |
| Title : Effects of Novel Tacrine Derivatives on Mitochondrial Energy Metabolism and Monoamine Oxidase Activity-In Vitro Study - Hroudova_2021_Mol.Neurobiol_58_1102 |
| Author(s) : Hroudova J , Novakova T , Korabecny J , Malinak D , Gorecki L , Fisar Z |
| Ref : Molecular Neurobiology , 58 :1102 , 2021 |
| Abstract : Hroudova_2021_Mol.Neurobiol_58_1102 |
| ESTHER : Hroudova_2021_Mol.Neurobiol_58_1102 |
| PubMedSearch : Hroudova_2021_Mol.Neurobiol_58_1102 |
| PubMedID: 33089424 |
| Title : Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease - Gorecki_2021_ACS.Chem.Neurosci__ |
| Author(s) : Gorecki L , Uliassi E , Bartolini M , Janockova J , Hrabinova M , Hepnarova V , Prchal L , Muckova L , Pejchal J , Karasova JZ , Mezeiova E , Benkova M , Kobrlova T , Soukup O , Petralla S , Monti B , Korabecny J , Bolognesi ML |
| Ref : ACS Chem Neurosci , : , 2021 |
| Abstract : Gorecki_2021_ACS.Chem.Neurosci__ |
| ESTHER : Gorecki_2021_ACS.Chem.Neurosci__ |
| PubMedSearch : Gorecki_2021_ACS.Chem.Neurosci__ |
| PubMedID: 33852284 |
| Title : Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors - Gorecki_2021_Eur.J.Med.Chem_219_113434 |
| Author(s) : Gorecki L , Misiachna A , Damborsky J , Dolezal R , Korabecny J , Cejkova L , Hakenova K , Chvojkova M , Karasova JZ , Prchal L , Novak M , Kolcheva M , Kortus S , Vales K , Horak M , Soukup O |
| Ref : Eur Journal of Medicinal Chemistry , 219 :113434 , 2021 |
| Abstract : Gorecki_2021_Eur.J.Med.Chem_219_113434 |
| ESTHER : Gorecki_2021_Eur.J.Med.Chem_219_113434 |
| PubMedSearch : Gorecki_2021_Eur.J.Med.Chem_219_113434 |
| PubMedID: 33892271 |
| Title : Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors - Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| Author(s) : Gorecki L , Andrys R , Schmidt M , Kucera T , Psotka M , Svobodova B , Hrabcova V , Hepnarova V , Bzonek P , Jun D , Kuca K , Korabecny J , Musilek K |
| Ref : ACS Med Chem Lett , 11 :65 , 2020 |
| Abstract : Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| ESTHER : Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| PubMedSearch : Gorecki_2020_ACS.Med.Chem.Lett_11_65 |
| PubMedID: 31938465 |
| Title : Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators - Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| Author(s) : Malinak D , Dolezal R , Hepnarova V , Hozova M , Andrys R , Bzonek P , Racakova V , Korabecny J , Gorecki L , Mezeiova E , Psotka M , Jun D , Kuca K , Musilek K |
| Ref : J Enzyme Inhib Med Chem , 35 :478 , 2020 |
| Abstract : Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| ESTHER : Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| PubMedSearch : Malinak_2020_J.Enzyme.Inhib.Med.Chem_35_478 |
| PubMedID: 31910701 |
| Title : Rational design, synthesis and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase - Gorecki_2020_J.Biol.Chem_295_4079 |
| Author(s) : Gorecki L , Gerlits O , Kong X , Cheng X , Blumenthal DK , Taylor P , Ballatore C , Kovalevsky A , Radic Z |
| Ref : Journal of Biological Chemistry , 295 :4079 , 2020 |
| Abstract : Gorecki_2020_J.Biol.Chem_295_4079 |
| ESTHER : Gorecki_2020_J.Biol.Chem_295_4079 |
| PubMedSearch : Gorecki_2020_J.Biol.Chem_295_4079 |
| PubMedID: 32019865 |
| Gene_locus related to this paper: human-ACHE |
| Title : Donepezil Derivatives Targeting Amyloid-beta Cascade in Alzheimer's Disease - Mezeiova_2019_Curr.Alzheimer.Res_16_772 |
| Author(s) : Mezeiova E , Chalupova K , Nepovimova E , Gorecki L , Prchal L , Malinak D , Kuca K , Soukup O , Korabecny J |
| Ref : Curr Alzheimer Res , 16 :772 , 2019 |
| Abstract : Mezeiova_2019_Curr.Alzheimer.Res_16_772 |
| ESTHER : Mezeiova_2019_Curr.Alzheimer.Res_16_772 |
| PubMedSearch : Mezeiova_2019_Curr.Alzheimer.Res_16_772 |
| PubMedID: 30819078 |
| Title : Tacroximes: novel unique compounds for the recovery of organophosphorus-inhibited acetylcholinesterase - Gorecki_2019_Future.Med.Chem_11_2625 |
| Author(s) : Gorecki L , Junova L , Kucera T , Hepnarova V , Prchal L , Kobrlova T , Muckova L , Soukup O , Korabecny J |
| Ref : Future Med Chem , 11 :2625 , 2019 |
| Abstract : Gorecki_2019_Future.Med.Chem_11_2625 |
| ESTHER : Gorecki_2019_Future.Med.Chem_11_2625 |
| PubMedSearch : Gorecki_2019_Future.Med.Chem_11_2625 |
| PubMedID: 31556693 |
| Title : Oxime K203: a drug candidate for the treatment of tabun intoxication - Gorecki_2019_Arch.Toxicol_93_673 |
| Author(s) : Gorecki L , Soukup O , Kucera T , Malinak D , Jun D , Kuca K , Musilek K , Korabecny J |
| Ref : Archives of Toxicology , 93 :673 , 2019 |
| Abstract : Gorecki_2019_Arch.Toxicol_93_673 |
| ESTHER : Gorecki_2019_Arch.Toxicol_93_673 |
| PubMedSearch : Gorecki_2019_Arch.Toxicol_93_673 |
| PubMedID: 30564897 |
| Title : A Review of the Synthesis of Quaternary Acetylcholinesterase Reactivators - Tsai_2021_J.Food.Drug.Anal_29_153 |
| Author(s) : Malinak D , Korabecny J , Soukup O , Gorecki L , Nepovimova E , Psotka M , Dolezal R , Nguyen TD , Mezeiova E , Musilek K , Kuca K |
| Ref : Current Organic Chemistry , 22\ :1619 , 2018 |
| Abstract : Tsai_2021_J.Food.Drug.Anal_29_153 |
| ESTHER : Tsai_2021_J.Food.Drug.Anal_29_153 |
| PubMedSearch : Tsai_2021_J.Food.Drug.Anal_29_153 |
| PubMedID: |
| Title : In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley? - Soukup_2018_Med.Chem_14_281 |
| Author(s) : Soukup O , Korabecny J , Malinak D , Nepovimova E , Pham NL , Musilek K , Hrabinova M , Hepnarova V , Dolezal R , Pavek P , Jost P , Kobrlova T , Jankockova J , Gorecki L , Psotka M , Nguyen TD , Box K , Outhwaite B , Ceckova M , Sorf A , Jun D , Kuca K |
| Ref : Med Chem , 14 :281 , 2018 |
| Abstract : Soukup_2018_Med.Chem_14_281 |
| ESTHER : Soukup_2018_Med.Chem_14_281 |
| PubMedSearch : Soukup_2018_Med.Chem_14_281 |
| PubMedID: 29332594 |
| Title : Profiling donepezil template into multipotent hybrids with antioxidant properties - Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| Author(s) : Mezeiova E , Spilovska K , Nepovimova E , Gorecki L , Soukup O , Dolezal R , Malinak D , Janockova J , Jun D , Kuca K , Korabecny J |
| Ref : J Enzyme Inhib Med Chem , 33 :583 , 2018 |
| Abstract : Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| ESTHER : Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| PubMedSearch : Mezeiova_2018_J.Enzyme.Inhib.Med.Chem_33_583 |
| PubMedID: 29529892 |
| Title : Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016) - Gorecki_2017_Expert.Opin.Ther.Pat_27_971 |
| Author(s) : Gorecki L , Korabecny J , Musilek K , Nepovimova E , Malinak D , Kucera T , Dolezal R , Jun D , Soukup O , Kuca K |
| Ref : Expert Opin Ther Pat , 27 :971 , 2017 |
| Abstract : Gorecki_2017_Expert.Opin.Ther.Pat_27_971 |
| ESTHER : Gorecki_2017_Expert.Opin.Ther.Pat_27_971 |
| PubMedSearch : Gorecki_2017_Expert.Opin.Ther.Pat_27_971 |
| PubMedID: 28569609 |
| Title : HLo-7 - A review of acetylcholinesterase reactivator against organophosphorus intoxication - Psotka_2017_Mil.Med.Sci.Lett_86_70 |
| Author(s) : Psotka M , Malinak D , Gorecki L , Nguyen TD , Soukup O , Jun D , Kuca K , Musilek K , Korabecny J |
| Ref : Military Medical Science Letters , 86 :70 , 2017 |
| Abstract : Psotka_2017_Mil.Med.Sci.Lett_86_70 |
| ESTHER : Psotka_2017_Mil.Med.Sci.Lett_86_70 |
| PubMedSearch : Psotka_2017_Mil.Med.Sci.Lett_86_70 |
| PubMedID: |
| Title : A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication - Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| Author(s) : Nepovimova E , Korabecny J , Dolezal R , Nguyen TD , Jun D , Soukup O , Pasdiorova M , Jost P , Muckova L , Malinak D , Gorecki L , Musilek K , Kuca K |
| Ref : Toxicol Res (Camb) , 5 :1012 , 2016 |
| Abstract : Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| ESTHER : Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| PubMedSearch : Nepovimova_2016_Toxicol.Res.(Camb)_5_1012 |
| PubMedID: 30090408 |
| Title : SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides - Gorecki_2016_Arch.Toxicol_90_2831 |
| Author(s) : Gorecki L , Korabecny J , Musilek K , Malinak D , Nepovimova E , Dolezal R , Jun D , Soukup O , Kuca K |
| Ref : Archives of Toxicology , 90 :2831 , 2016 |
| Abstract : Gorecki_2016_Arch.Toxicol_90_2831 |
| ESTHER : Gorecki_2016_Arch.Toxicol_90_2831 |
| PubMedSearch : Gorecki_2016_Arch.Toxicol_90_2831 |
| PubMedID: 27582056 |
| Title : 7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment - Korabecny_2015_Molecules_20_22084 |
| Author(s) : Korabecny J , Andrs M , Nepovimova E , Dolezal R , Babkova K , Horova A , Malinak D , Mezeiova E , Gorecki L , Sepsova V , Hrabinova M , Soukup O , Jun D , Kuca K |
| Ref : Molecules , 20 :22084 , 2015 |
| Abstract : Korabecny_2015_Molecules_20_22084 |
| ESTHER : Korabecny_2015_Molecules_20_22084 |
| PubMedSearch : Korabecny_2015_Molecules_20_22084 |
| PubMedID: 26690394 |