Biblio print

Tree Display

AceDB Schema

XML Display


Author Report for: Gorecki L

Contact information:

Gorecki Lukas
Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove
Czech Republic
Phone :
Fax :
Send E-Mail to Gorecki Lukas

    Title: Countermeasures in organophosphorus intoxication: pitfalls and prospects
    Gorecki L, Soukup O, Korabecny J
    Ref: Trends in Pharmacological Sciences, :, 2022 : PubMed


    Title: Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides
    Hepnarova V, Hrabinova M, Muckova L, Kucera T, Schmidt M, Dolezal R, Gorecki L, Hrabcova V, Korabecny J and Pejchal J <2 more author(s)>
    Ref: Toxicol In Vitro, :105463, 2022 : PubMed


    Title: Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
    Gorecki L, Hepnarova V, Karasova JZ, Hrabinova M, Courageux C, Dias J, Kucera T, Kobrlova T, Muckova L and Korabecny J <7 more author(s)>
    Ref: Archives of Toxicology, :, 2021 : PubMed


    Title: Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease
    Gorecki L, Uliassi E, Bartolini M, Janockova J, Hrabinova M, Hepnarova V, Prchal L, Muckova L, Pejchal J and Bolognesi ML <8 more author(s)>
    Ref: ACS Chem Neurosci, :, 2021 : PubMed


    Title: Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors
    Gorecki L, Misiachna A, Damborsky J, Dolezal R, Korabecny J, Cejkova L, Hakenova K, Chvojkova M, Karasova JZ and Soukup O <6 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 219:113434, 2021 : PubMed


    Title: Effects of Novel Tacrine Derivatives on Mitochondrial Energy Metabolism and Monoamine Oxidase Activity-In Vitro Study
    Hroudova J, Novakova T, Korabecny J, Malinak D, Gorecki L, Fisar Z
    Ref: Molecular Neurobiology, 58:1102, 2021 : PubMed


    Title: Huprine Y - tryptophan heterodimers with potential implication to Alzheimer's disease treatment
    Mezeiova E, Hrabinova M, Hepnarova V, Jun D, Janockova J, Muckova L, Prchal L, Kristofikova Z, Kucera T and Korabecny J <5 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, :128100, 2021 : PubMed


    Title: Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors
    Gorecki L, Andrys R, Schmidt M, Kucera T, Psotka M, Svobodova B, Hrabcova V, Hepnarova V, Bzonek P and Musilek K <3 more author(s)>
    Ref: ACS Med Chem Lett, 11:65, 2020 : PubMed


    Title: Rational design, synthesis and evaluation of uncharged, smart bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase
    Gorecki L, Gerlits O, Kong X, Cheng X, Blumenthal DK, Taylor P, Ballatore C, Kovalevsky A, Radic Z
    Ref: Journal of Biological Chemistry, 295:4079, 2020 : PubMed


    Title: Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
    Malinak D, Dolezal R, Hepnarova V, Hozova M, Andrys R, Bzonek P, Racakova V, Korabecny J, Gorecki L and Musilek K <4 more author(s)>
    Ref: J Enzyme Inhib Med Chem, 35:478, 2020 : PubMed


    Title: Oxime K203: a drug candidate for the treatment of tabun intoxication
    Gorecki L, Soukup O, Kucera T, Malinak D, Jun D, Kuca K, Musilek K, Korabecny J
    Ref: Archives of Toxicology, 93:673, 2019 : PubMed


    Title: Tacroximes: novel unique compounds for the recovery of organophosphorus-inhibited acetylcholinesterase
    Gorecki L, Junova L, Kucera T, Hepnarova V, Prchal L, Kobrlova T, Muckova L, Soukup O, Korabecny J
    Ref: Future Med Chem, 11:2625, 2019 : PubMed


    Title: Donepezil Derivatives Targeting Amyloid-beta Cascade in Alzheimer's Disease
    Mezeiova E, Chalupova K, Nepovimova E, Gorecki L, Prchal L, Malinak D, Kuca K, Soukup O, Korabecny J
    Ref: Curr Alzheimer Res, 16:772, 2019 : PubMed


    Title: Profiling donepezil template into multipotent hybrids with antioxidant properties
    Mezeiova E, Spilovska K, Nepovimova E, Gorecki L, Soukup O, Dolezal R, Malinak D, Janockova J, Jun D and Korabecny J <1 more author(s)>
    Ref: J Enzyme Inhib Med Chem, 33:583, 2018 : PubMed


    Title: In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
    Soukup O, Korabecny J, Malinak D, Nepovimova E, Pham NL, Musilek K, Hrabinova M, Hepnarova V, Dolezal R and Kuca K <12 more author(s)>
    Ref: Med Chem, 14:281, 2018 : PubMed


    Title: Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006-2016)
    Gorecki L, Korabecny J, Musilek K, Nepovimova E, Malinak D, Kucera T, Dolezal R, Jun D, Soukup O, Kuca K
    Ref: Expert Opin Ther Pat, 27:971, 2017 : PubMed


    Title: HLo-7 - A review of acetylcholinesterase reactivator against organophosphorus intoxication
    Psotka M, Malinak D, Gorecki L, Nguyen TD, Soukup O, Jun D, Kuca K, Musilek K, Korabecny J
    Ref: Military Medical Science Letters, 86:70, 2017 : PubMed


    Title: SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides
    Gorecki L, Korabecny J, Musilek K, Malinak D, Nepovimova E, Dolezal R, Jun D, Soukup O, Kuca K
    Ref: Archives of Toxicology, 90:2831, 2016 : PubMed


    Title: A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication
    Nepovimova E, Korabecny J, Dolezal R, Nguyen TD, Jun D, Soukup O, Pasdiorova M, Jost P, Muckova L and Kuca K <3 more author(s)>
    Ref: Toxicol Res (Camb), 5:1012, 2016 : PubMed


    Title: 7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment
    Korabecny J, Andrs M, Nepovimova E, Dolezal R, Babkova K, Horova A, Malinak D, Mezeiova E, Gorecki L and Kuca K <4 more author(s)>
    Ref: Molecules, 20:22084, 2015 : PubMed


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer