Full name : Han Yi-Fan
First name : Yi-Fan
Mail : The Hong Kong Polytechnic University, Department of Applied Biology and Chemical Technology, Room Y842, 8\/F, Block Y, The Hong Kong PolyU, Hunghom, KLN, Hong Kong
Zip Code :
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Country : China
Email : yifan.han@polyu.edu.hk
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Directory :
| Title : Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice - Chen_2018_Front.Cell.Neurosci_12_396 |
| Author(s) : Chen H , Wu X , Gu X , Zhou Y , Ye L , Zhang K , Pan H , Wang J , Wei H , Zhu B , Naman CB , Mak SH , Carlier PR , Cui W , Han YF |
| Ref : Front Cell Neurosci , 12 :396 , 2018 |
| Abstract : Chen_2018_Front.Cell.Neurosci_12_396 |
| ESTHER : Chen_2018_Front.Cell.Neurosci_12_396 |
| PubMedSearch : Chen_2018_Front.Cell.Neurosci_12_396 |
| PubMedID: 30483056 |
| Title : Sunitinib, a Clinically Used Anticancer Drug, Is a Potent AChE Inhibitor and Attenuates Cognitive Impairments in Mice - Huang_2016_ACS.Chem.Neurosci_7_1047 |
| Author(s) : Huang L , Lin J , Xiang S , Zhao K , Yu J , Zheng J , Xu D , Mak SH , Hu S , Nirasha S , Wang C , Chen X , Zhang J , Xu S , Wei X , Zhang Z , Zhou D , Zhou W , Cui W , Han YF , Hu Z , Wang Q |
| Ref : ACS Chem Neurosci , 7 :1047 , 2016 |
| Abstract : Huang_2016_ACS.Chem.Neurosci_7_1047 |
| ESTHER : Huang_2016_ACS.Chem.Neurosci_7_1047 |
| PubMedSearch : Huang_2016_ACS.Chem.Neurosci_7_1047 |
| PubMedID: 27046396 |
| Title : Dimeric bis (heptyl)-Cognitin Blocks Alzheimer's beta-Amyloid Neurotoxicity Via the Inhibition of Abeta Fibrils Formation and Disaggregation of Preformed Fibrils - Hu_2015_CNS.Neurosci.Ther_21_953 |
| Author(s) : Hu SQ , Wang R , Cui W , Mak SH , Li G , Hu YJ , Lee MY , Pang YP , Han YF |
| Ref : CNS Neurosci Ther , 21 :953 , 2015 |
| Abstract : Hu_2015_CNS.Neurosci.Ther_21_953 |
| ESTHER : Hu_2015_CNS.Neurosci.Ther_21_953 |
| PubMedSearch : Hu_2015_CNS.Neurosci.Ther_21_953 |
| PubMedID: 26507365 |
| Title : Protection against beta-amyloid-induced synaptic and memory impairments via altering beta-amyloid assembly by bis(heptyl)-cognitin - Chang_2015_Sci.Rep_5_10256 |
| Author(s) : Chang L , Cui W , Yang Y , Xu S , Zhou WH , Fu HJ , Hu SQ , Mak SH , Hu JW , Wang Q , Pui-Yan Ma V , Chung-Lit Choi T , Dik-Lung Ma E , Tao L , Pang YP , Rowan MJ , Anwyl R , Han YF |
| Ref : Sci Rep , 5 :10256 , 2015 |
| Abstract : Chang_2015_Sci.Rep_5_10256 |
| ESTHER : Chang_2015_Sci.Rep_5_10256 |
| PubMedSearch : Chang_2015_Sci.Rep_5_10256 |
| PubMedID: 26194093 |
| Title : Substantial Neuroprotection Against K(+) Deprivation-Induced Apoptosis in Primary Cerebellar Granule Neurons by Novel Dimer Bis(propyl)-Cognitin Via the Activation of VEGFR-2 Signaling Pathway - Hu_2013_CNS.Neurosci.Ther_19_764 |
| Author(s) : Hu SQ , Cui W , Xu DP , Mak SH , Tang J , Choi CL , Pang YP , Han YF |
| Ref : CNS Neurosci Ther , 19 :764 , 2013 |
| Abstract : Hu_2013_CNS.Neurosci.Ther_19_764 |
| ESTHER : Hu_2013_CNS.Neurosci.Ther_19_764 |
| PubMedSearch : Hu_2013_CNS.Neurosci.Ther_19_764 |
| PubMedID: 23826635 |
| Title : Reversal of scopolamine-induced spatial and recognition memory deficits in mice by novel multifunctional dimers bis-cognitins - Han_2012_Brain.Res_1470_59 |
| Author(s) : Han RW , Zhang RS , Chang M , Peng YL , Wang P , Hu SQ , Choi CL , Yin M , Wang R , Han YF |
| Ref : Brain Research , 1470 :59 , 2012 |
| Abstract : Han_2012_Brain.Res_1470_59 |
| ESTHER : Han_2012_Brain.Res_1470_59 |
| PubMedSearch : Han_2012_Brain.Res_1470_59 |
| PubMedID: 22750583 |
| Title : Tacrine(2)-ferulic acid, a novel multifunctional dimer, attenuates 6-hydroxydopamine-induced apoptosis in PC12 cells by activating Akt pathway - Zhang_2011_Neurochem.Int_59_981 |
| Author(s) : Zhang H , Mak SH , Cui W , Li W , Han R , Hu S , Ye M , Pi R , Han YF |
| Ref : Neurochem Int , 59 :981 , 2011 |
| Abstract : Zhang_2011_Neurochem.Int_59_981 |
| ESTHER : Zhang_2011_Neurochem.Int_59_981 |
| PubMedSearch : Zhang_2011_Neurochem.Int_59_981 |
| PubMedID: 21939707 |
| Title : Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR - Cui_2011_Brain.Res_1401_10 |
| Author(s) : Cui W , Cui GZ , Li W , Zhang Z , Hu S , Mak SH , Zhang H , Carlier PR , Choi CL , Wong YT , Lee SM , Han YF |
| Ref : Brain Research , 1401 :10 , 2011 |
| Abstract : Cui_2011_Brain.Res_1401_10 |
| ESTHER : Cui_2011_Brain.Res_1401_10 |
| PubMedSearch : Cui_2011_Brain.Res_1401_10 |
| PubMedID: 21665194 |
| Title : Preventing H(2)O(2)-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2\/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone - Cui_2011_Brain.Res_1394_14 |
| Author(s) : Cui W , Li W , Zhao Y , Mak SH , Gao Y , Luo J , Zhang H , Liu Y , Carlier PR , Rong J , Han YF |
| Ref : Brain Research , 1394 :14 , 2011 |
| Abstract : Cui_2011_Brain.Res_1394_14 |
| ESTHER : Cui_2011_Brain.Res_1394_14 |
| PubMedSearch : Cui_2011_Brain.Res_1394_14 |
| PubMedID: 21315693 |
| Title : Tacrine treatment at high dose suppresses the recognition memory in juvenile and adult mice with attention to hepatotoxicity - Pan_2011_Basic.Clin.Pharmacol.Toxicol_108_421 |
| Author(s) : Pan SY , Guo BF , Zhang Y , Yu Q , Yu ZL , Dong H , Ye Y , Han YF , Ko KM |
| Ref : Basic Clin Pharmacol Toxicol , 108 :421 , 2011 |
| Abstract : Pan_2011_Basic.Clin.Pharmacol.Toxicol_108_421 |
| ESTHER : Pan_2011_Basic.Clin.Pharmacol.Toxicol_108_421 |
| PubMedSearch : Pan_2011_Basic.Clin.Pharmacol.Toxicol_108_421 |
| PubMedID: 21232021 |
| Title : Mechanism of bis(7)-tacrine inhibition of GABA-activated current in cultured rat hippocampal neurons - Zhou_2009_Neuropharmacol_57_33 |
| Author(s) : Zhou L , Liu YW , Peoples RW , Yang M , Tian X , Ai YX , Pang YP , Li ZW , Han YF , Li CY |
| Ref : Neuropharmacology , 57 :33 , 2009 |
| Abstract : Zhou_2009_Neuropharmacol_57_33 |
| ESTHER : Zhou_2009_Neuropharmacol_57_33 |
| PubMedSearch : Zhou_2009_Neuropharmacol_57_33 |
| PubMedID: 19393253 |
| Title : Inhibition of NMDA-gated ion channels by bis(7)-tacrine: whole-cell and single-channel studies - Liu_2008_Neuropharmacol_54_1086 |
| Author(s) : Liu YW , Luo JL , Ren H , Peoples RW , Ai YX , Liu LJ , Pang YP , Li ZW , Han YF , Li CY |
| Ref : Neuropharmacology , 54 :1086 , 2008 |
| Abstract : Liu_2008_Neuropharmacol_54_1086 |
| ESTHER : Liu_2008_Neuropharmacol_54_1086 |
| PubMedSearch : Liu_2008_Neuropharmacol_54_1086 |
| PubMedID: 18407299 |
| Title : The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine - Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| Author(s) : Yu H , Li WM , Kan KK , Ho JM , Carlier PR , Pang YP , Gu ZM , Zhong Z , Chan K , Wang YT , Han YF |
| Ref : J Pharm Biomed Anal , 46 :75 , 2008 |
| Abstract : Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| ESTHER : Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| PubMedSearch : Yu_2008_J.Pharm.Biomed.Anal_46_75 |
| PubMedID: 17931815 |
| Title : Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry - Zhang_2008_Biomed.Chromatogr_22_414 |
| Author(s) : Zhang L , Yu H , Li WM , Cheung MC , Pang YP , Lin G , Wang YT , Zuo Z , Han YF |
| Ref : Biomedical Chromatography , 22 :414 , 2008 |
| Abstract : Zhang_2008_Biomed.Chromatogr_22_414 |
| ESTHER : Zhang_2008_Biomed.Chromatogr_22_414 |
| PubMedSearch : Zhang_2008_Biomed.Chromatogr_22_414 |
| PubMedID: 18059054 |
| Title : East meets West in the search for Alzheimer's therapeutics - novel dimeric inhibitors from tacrine and huperzine A - Li_2007_Curr.Alzheimer.Res_4_386 |
| Author(s) : Li WM , Kan KK , Carlier PR , Pang YP , Han YF |
| Ref : Curr Alzheimer Res , 4 :386 , 2007 |
| Abstract : Li_2007_Curr.Alzheimer.Res_4_386 |
| ESTHER : Li_2007_Curr.Alzheimer.Res_4_386 |
| PubMedSearch : Li_2007_Curr.Alzheimer.Res_4_386 |
| PubMedID: 17908041 |
| Title : Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity - Wong_2003_J.Am.Chem.Soc_125_363 |
| Author(s) : Wong DM , Greenblatt HM , Dvir H , Carlier PR , Han YF , Pang YP , Silman I , Sussman JL |
| Ref : J Am Chem Soc , 125 :363 , 2003 |
| Abstract : Wong_2003_J.Am.Chem.Soc_125_363 |
| ESTHER : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedSearch : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedID: 12517147 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine - Xiao_2000_Neurosci.Lett_290_197 |
| Author(s) : Xiao XQ , Lee NT , Carlier PR , Pang Y , Han YF |
| Ref : Neuroscience Letters , 290 :197 , 2000 |
| Abstract : Xiao_2000_Neurosci.Lett_290_197 |
| ESTHER : Xiao_2000_Neurosci.Lett_290_197 |
| PubMedSearch : Xiao_2000_Neurosci.Lett_290_197 |
| PubMedID: 10963897 |
| Title : Learning deficits induced by 4 belladonna alkaloids are preferentially attenuated by tacrine - Pan_2000_Acta.Pharmacol.Sin_21_124 |
| Author(s) : Pan SY , Han YF |
| Ref : Acta Pharmacol Sin , 21 :124 , 2000 |
| Abstract : Pan_2000_Acta.Pharmacol.Sin_21_124 |
| ESTHER : Pan_2000_Acta.Pharmacol.Sin_21_124 |
| PubMedSearch : Pan_2000_Acta.Pharmacol.Sin_21_124 |
| PubMedID: 11263258 |
| Title : Huperzine A improves cognitive deficits caused by chronic cerebral hypoperfusion in rats - Wang_2000_Eur.J.Pharmacol_398_65 |
| Author(s) : Wang LM , Han YF , Tang XC |
| Ref : European Journal of Pharmacology , 398 :65 , 2000 |
| Abstract : Wang_2000_Eur.J.Pharmacol_398_65 |
| ESTHER : Wang_2000_Eur.J.Pharmacol_398_65 |
| PubMedSearch : Wang_2000_Eur.J.Pharmacol_398_65 |
| PubMedID: 10856449 |
| Title : Protective effects of huperzine A on beta-amyloid(25-35) induced oxidative injury in rat pheochromocytoma cells - Xiao_2000_Neurosci.Lett_286_155 |
| Author(s) : Xiao XQ , Wang R , Han YF , Tang XC |
| Ref : Neuroscience Letters , 286 :155 , 2000 |
| Abstract : Xiao_2000_Neurosci.Lett_286_155 |
| ESTHER : Xiao_2000_Neurosci.Lett_286_155 |
| PubMedSearch : Xiao_2000_Neurosci.Lett_286_155 |
| PubMedID: 10832008 |
| Title : Dimerization of an Inactive Fragment of Huperzine A Produces a Drug with Twice the Potency of the Natural Product - |
| Author(s) : Carlier PR , Du DM , Han YF , Liu J , Perola E , Williams ID , Pang YP |
| Ref : Angew Chem Int Ed Engl , 39 :1775 , 2000 |
| PubMedID: 10934357 |
| Title : Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor [corrected] - Wu_2000_Neurosci.Lett_288_95 |
| Author(s) : Wu DC , Xiao XQ , Ng AK , Chen PM , Chung W , Lee NT , Carlier PR , Pang YP , Yu AC , Han YF |
| Ref : Neuroscience Letters , 288 :95 , 2000 |
| Abstract : Wu_2000_Neurosci.Lett_288_95 |
| ESTHER : Wu_2000_Neurosci.Lett_288_95 |
| PubMedSearch : Wu_2000_Neurosci.Lett_288_95 |
| PubMedID: 10876069 |
| Title : Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities - Han_1999_Bioorg.Med.Chem_7_2569 |
| Author(s) : Han YF , Li CP , Chow E , Wang H , Pang YP , Carlier PR |
| Ref : Bioorganic & Medicinal Chemistry , 7 :2569 , 1999 |
| Abstract : Han_1999_Bioorg.Med.Chem_7_2569 |
| ESTHER : Han_1999_Bioorg.Med.Chem_7_2569 |
| PubMedSearch : Han_1999_Bioorg.Med.Chem_7_2569 |
| PubMedID: 10632067 |
| Title : Evaluation of short-tether bis-THA AChE inhibitors. A further test of the dual binding site hypothesis - Carlier_1999_Bioorg.Med.Chem_7_351 |
| Author(s) : Carlier PR , Han YF , Chow ES , Li CP , Wang H , Lieu TX , Wong HS , Pang YP |
| Ref : Bioorganic & Medicinal Chemistry , 7 :351 , 1999 |
| Abstract : Carlier_1999_Bioorg.Med.Chem_7_351 |
| ESTHER : Carlier_1999_Bioorg.Med.Chem_7_351 |
| PubMedSearch : Carlier_1999_Bioorg.Med.Chem_7_351 |
| PubMedID: 10218828 |
| Title : Bis(7)-tacrine, a novel dimeric AChE inhibitor, is a potent GABA(A) receptor antagonist - Li_1999_Neuroreport_10_795 |
| Author(s) : Li CY , Wang H , Xue H , Carlier PR , Hui KM , Pang YP , Li ZW , Han YF |
| Ref : Neuroreport , 10 :795 , 1999 |
| Abstract : Li_1999_Neuroreport_10_795 |
| ESTHER : Li_1999_Neuroreport_10_795 |
| PubMedSearch : Li_1999_Neuroreport_10_795 |
| PubMedID: 10208550 |
| Title : Effects of bis(7)-tacrine, a novel anti-Alzheimer's agent, on rat brain AChE - Wang_1999_Neuroreport_10_789 |
| Author(s) : Wang H , Carlier PR , Ho WL , Wu DC , Lee NT , Li CP , Pang YP , Han YF |
| Ref : Neuroreport , 10 :789 , 1999 |
| Abstract : Wang_1999_Neuroreport_10_789 |
| ESTHER : Wang_1999_Neuroreport_10_789 |
| PubMedSearch : Wang_1999_Neuroreport_10_789 |
| PubMedID: 10208549 |
| Title : Attenuation of scopolamine-induced deficits in navigational memory performance in rats by bis(7)-tacrine, a novel dimeric AChE inhibitor - Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| Author(s) : Wang H , Carlier PR , Ho WL , Lee NT , Pang YP , Han YF |
| Ref : Zhongguo Yao Li Xue Bao , 20 :211 , 1999 |
| Abstract : Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| ESTHER : Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| PubMedSearch : Wang_1999_Zhongguo.Yao.Li.Xue.Bao_20_211 |
| PubMedID: 10452094 |