Full name : Jakubik Jan
First name : Jan
Mail : Department of Neurochemistry, Institute of Physiology, Academy of Sciences of the Czech Republic,Videnska 1083, CZ-14220 Prague
Zip Code :
City :
Country : Czech Republic
Email : jan.jakubik@fgu.cas.cz
Phone :
Fax :
Website : \/\/www.researchgate.net\/profile\/Jan_Jakubik2
Directory :
| Title : Lipid-Based Diets Improve Muscarinic Neurotransmission in the Hippocampus of Transgenic APPswe\/PS1dE9 Mice - Janickova_2015_Curr.Alzheimer.Res_12_923 |
| Author(s) : Janickova H , Rudajev V , Dolejsi E , Koivisto H , Jakubik J , Tanila H , El-Fakahany EE , Dolezal V |
| Ref : Curr Alzheimer Res , 12 :923 , 2015 |
| Abstract : Janickova_2015_Curr.Alzheimer.Res_12_923 |
| ESTHER : Janickova_2015_Curr.Alzheimer.Res_12_923 |
| PubMedSearch : Janickova_2015_Curr.Alzheimer.Res_12_923 |
| PubMedID: 26502816 |
| Title : Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms - Randakova_2015_Pharmacol.Res_97_27 |
| Author(s) : Randakova A , Dolejsi E , Rudajev V , Zimcik P , Dolezal V , El-Fakahany EE , Jakubik J |
| Ref : Pharmacol Res , 97 :27 , 2015 |
| Abstract : Randakova_2015_Pharmacol.Res_97_27 |
| ESTHER : Randakova_2015_Pharmacol.Res_97_27 |
| PubMedSearch : Randakova_2015_Pharmacol.Res_97_27 |
| PubMedID: 25882246 |
| Title : Outline of therapeutic interventions with muscarinic receptor-mediated transmission - Jakubik_2014_Physiol.Res_63 Suppl 1_S177 |
| Author(s) : Jakubik J , Santruckova E , Randakova A , Janickova H , Zimcik P , Rudajev V , Michal P , El-Fakahany EE , Dolezal V |
| Ref : Physiol Res , 63 Suppl 1 :S177 , 2014 |
| Abstract : Jakubik_2014_Physiol.Res_63 Suppl 1_S177 |
| ESTHER : Jakubik_2014_Physiol.Res_63 Suppl 1_S177 |
| PubMedSearch : Jakubik_2014_Physiol.Res_63 Suppl 1_S177 |
| PubMedID: 24564657 |
| Title : On homology modeling of the M2 muscarinic acetylcholine receptor subtype - Jakubik_2013_J.Comput.Aided.Mol.Des_27_525 |
| Author(s) : Jakubik J , Randakova A , Dolezal V |
| Ref : J Comput Aided Mol Des , 27 :525 , 2013 |
| Abstract : Jakubik_2013_J.Comput.Aided.Mol.Des_27_525 |
| ESTHER : Jakubik_2013_J.Comput.Aided.Mol.Des_27_525 |
| PubMedSearch : Jakubik_2013_J.Comput.Aided.Mol.Des_27_525 |
| PubMedID: 23812908 |
| Title : Uncoupling of M1 muscarinic receptor\/G-protein interaction by amyloid beta(1-42) - Janickova_2013_Neuropharmacol_67_272 |
| Author(s) : Janickova H , Rudajev V , Zimcik P , Jakubik J , Tanila H , El-Fakahany EE , Dolezal V |
| Ref : Neuropharmacology , 67 :272 , 2013 |
| Abstract : Janickova_2013_Neuropharmacol_67_272 |
| ESTHER : Janickova_2013_Neuropharmacol_67_272 |
| PubMedSearch : Janickova_2013_Neuropharmacol_67_272 |
| PubMedID: 23206502 |
| Title : Subtype differences in pre-coupling of muscarinic acetylcholine receptors - Jakubik_2011_PLoS.One_6_e27732 |
| Author(s) : Jakubik J , Janickova H , Randakova A , El-Fakahany EE , Dolezal V |
| Ref : PLoS ONE , 6 :e27732 , 2011 |
| Abstract : Jakubik_2011_PLoS.One_6_e27732 |
| ESTHER : Jakubik_2011_PLoS.One_6_e27732 |
| PubMedSearch : Jakubik_2011_PLoS.One_6_e27732 |
| PubMedID: 22110745 |
| Title : Pharmacological evaluation of the long-term effects of xanomeline on the M(1) muscarinic acetylcholine receptor - Grant_2010_PLoS.One_5_e15722 |
| Author(s) : Grant MK , Noetzel MJ , De Lorme KC , Jakubik J , Dolezal V , El-Fakahany EE |
| Ref : PLoS ONE , 5 :e15722 , 2010 |
| Abstract : Grant_2010_PLoS.One_5_e15722 |
| ESTHER : Grant_2010_PLoS.One_5_e15722 |
| PubMedSearch : Grant_2010_PLoS.One_5_e15722 |
| PubMedID: 21203415 |
| Title : Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors - Mordvintsev_2009_FEBS.J_276_5065 |
| Author(s) : Mordvintsev DY , Polyak YL , Rodionov DI , Jakubik J , Dolezal V , Karlsson E , Tsetlin VI , Utkin YN |
| Ref : Febs J , 276 :5065 , 2009 |
| Abstract : Mordvintsev_2009_FEBS.J_276_5065 |
| ESTHER : Mordvintsev_2009_FEBS.J_276_5065 |
| PubMedSearch : Mordvintsev_2009_FEBS.J_276_5065 |
| PubMedID: 19682302 |
| Title : Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors - Jakubik_2009_BMC.Pharmacol_9_15 |
| Author(s) : Jakubik J , Randakova A , El-Fakahany EE , Dolezal V |
| Ref : BMC Pharmacol , 9 :15 , 2009 |
| Abstract : Jakubik_2009_BMC.Pharmacol_9_15 |
| ESTHER : Jakubik_2009_BMC.Pharmacol_9_15 |
| PubMedSearch : Jakubik_2009_BMC.Pharmacol_9_15 |
| PubMedID: 20038295 |
| Title : Importance and prospects for design of selective muscarinic agonists - Jakubik_2008_Physiol.Res_57 Suppl 3_S39 |
| Author(s) : Jakubik J , Michal P , Machova E , Dolezal V |
| Ref : Physiol Res , 57 Suppl 3 :S39 , 2008 |
| Abstract : Jakubik_2008_Physiol.Res_57 Suppl 3_S39 |
| ESTHER : Jakubik_2008_Physiol.Res_57 Suppl 3_S39 |
| PubMedSearch : Jakubik_2008_Physiol.Res_57 Suppl 3_S39 |
| PubMedID: 18481916 |
| Title : Impairment of muscarinic transmission in transgenic APPswe\/PS1dE9 mice - Machova_2008_Neurobiol.Aging_29_368 |
| Author(s) : Machova E , Jakubik J , Michal P , Oksman M , Iivonen H , Tanila H , Dolezal V |
| Ref : Neurobiology of Aging , 29 :368 , 2008 |
| Abstract : Machova_2008_Neurobiol.Aging_29_368 |
| ESTHER : Machova_2008_Neurobiol.Aging_29_368 |
| PubMedSearch : Machova_2008_Neurobiol.Aging_29_368 |
| PubMedID: 17140703 |
| Title : Wash-resistantly bound xanomeline inhibits acetylcholine release by persistent activation of presynaptic M(2) and M(4) muscarinic receptors in rat brain - Machova_2007_J.Pharmacol.Exp.Ther_322_316 |
| Author(s) : Machova E , Jakubik J , El-Fakahany EE , Dolezal V |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 322 :316 , 2007 |
| Abstract : Machova_2007_J.Pharmacol.Exp.Ther_322_316 |
| ESTHER : Machova_2007_J.Pharmacol.Exp.Ther_322_316 |
| PubMedSearch : Machova_2007_J.Pharmacol.Exp.Ther_322_316 |
| PubMedID: 17446301 |
| Title : Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors - Jakubik_2006_Mol.Pharmacol_70_656 |
| Author(s) : Jakubik J , El-Fakahany EE , Dolezal V |
| Ref : Molecular Pharmacology , 70 :656 , 2006 |
| Abstract : Jakubik_2006_Mol.Pharmacol_70_656 |
| ESTHER : Jakubik_2006_Mol.Pharmacol_70_656 |
| PubMedSearch : Jakubik_2006_Mol.Pharmacol_70_656 |
| PubMedID: 16675658 |
| Title : Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors - Jakubik_2006_J.Mol.Neurosci_30_111 |
| Author(s) : Jakubik J , Dolezal V |
| Ref : Journal of Molecular Neuroscience , 30 :111 , 2006 |
| Abstract : Jakubik_2006_J.Mol.Neurosci_30_111 |
| ESTHER : Jakubik_2006_J.Mol.Neurosci_30_111 |
| PubMedSearch : Jakubik_2006_J.Mol.Neurosci_30_111 |
| PubMedID: 17192652 |
| Title : Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators - Jakubik_2005_J.Pharmacol.Exp.Ther_313_688 |
| Author(s) : Jakubik J , Krejci A , Dolezal V |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 313 :688 , 2005 |
| Abstract : Jakubik_2005_J.Pharmacol.Exp.Ther_313_688 |
| ESTHER : Jakubik_2005_J.Pharmacol.Exp.Ther_313_688 |
| PubMedSearch : Jakubik_2005_J.Pharmacol.Exp.Ther_313_688 |
| PubMedID: 15647330 |
| Title : Regulation of signal transduction at M2 muscarinic receptor - Krejci_2004_Physiol.Res_53 Suppl 1_S131 |
| Author(s) : Krejci A , Michal P , Jakubik J , Ricny J , Dolezal V |
| Ref : Physiol Res , 53 Suppl 1 :S131 , 2004 |
| Abstract : Krejci_2004_Physiol.Res_53 Suppl 1_S131 |
| ESTHER : Krejci_2004_Physiol.Res_53 Suppl 1_S131 |
| PubMedSearch : Krejci_2004_Physiol.Res_53 Suppl 1_S131 |
| PubMedID: 15119944 |
| Title : Roles of external loops of muscarinic receptors in interactions between N-methylscopolamine and allosteric modulators. - |
| Author(s) : Tucek S , Krejci A , Lysikova M , Jakubik J , Dolezal V |
| Ref : Cholinergic Mechanisms, CRC Press :71 , 2004 |
| PubMedID: |
| Title : Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor - Jakubik_2002_J.Pharmacol.Exp.Ther_301_1033 |
| Author(s) : Jakubik J , Tucek S , El-Fakahany EE |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 301 :1033 , 2002 |
| Abstract : Jakubik_2002_J.Pharmacol.Exp.Ther_301_1033 |
| ESTHER : Jakubik_2002_J.Pharmacol.Exp.Ther_301_1033 |
| PubMedSearch : Jakubik_2002_J.Pharmacol.Exp.Ther_301_1033 |
| PubMedID: 12023535 |
| Title : Evidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptors - Jakubik_2000_J.Biol.Chem_275_18836 |
| Author(s) : Jakubik J , El-Fakahany EE , Tucek S |
| Ref : Journal of Biological Chemistry , 275 :18836 , 2000 |
| Abstract : Jakubik_2000_J.Biol.Chem_275_18836 |
| ESTHER : Jakubik_2000_J.Biol.Chem_275_18836 |
| PubMedSearch : Jakubik_2000_J.Biol.Chem_275_18836 |
| PubMedID: 10749854 |
| Title : Subtype-selective inhibition of [methyl-3H]-N-methylscopolamine binding to muscarinic receptors by alpha-truxillic acid esters - Lysikova_1999_Br.J.Pharmacol_127_1240 |
| Author(s) : Lysikova M , Fuksova K , Elbert T , Jakubik J , Tucek S |
| Ref : British Journal of Pharmacology , 127 :1240 , 1999 |
| Abstract : Lysikova_1999_Br.J.Pharmacol_127_1240 |
| ESTHER : Lysikova_1999_Br.J.Pharmacol_127_1240 |
| PubMedSearch : Lysikova_1999_Br.J.Pharmacol_127_1240 |
| PubMedID: 10455271 |
| Title : Positive effects of allosteric modulators on the binding properties and the function of muscarinic acetylcholine receptors - Tucek_1998_J.Physiol.Paris_92_241 |
| Author(s) : Tucek S , Jakubik J , Dolezal V , El-Fakahany EE |
| Ref : Journal de Physiologie (Paris) , 92 :241 , 1998 |
| Abstract : Tucek_1998_J.Physiol.Paris_92_241 |
| ESTHER : Tucek_1998_J.Physiol.Paris_92_241 |
| PubMedSearch : Tucek_1998_J.Physiol.Paris_92_241 |
| PubMedID: 9789816 |
| Title : Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors - Jakubik_1997_Mol.Pharmacol_52_172 |
| Author(s) : Jakubik J , Bacakova L , El-Fakahany EE , Tucek S |
| Ref : Molecular Pharmacology , 52 :172 , 1997 |
| Abstract : Jakubik_1997_Mol.Pharmacol_52_172 |
| ESTHER : Jakubik_1997_Mol.Pharmacol_52_172 |
| PubMedSearch : Jakubik_1997_Mol.Pharmacol_52_172 |
| PubMedID: 9224827 |
| Title : Poster: Evidence for the presence of two sites for classical ligands on muscarinic receptors - |
| Author(s) : Tucek S , Jakubik J , Bacakova L , El-Fakahany EE |
| Ref : Life Sciences , 60 :1174 , 1997 |
| PubMedID: |
| Title : Activation of muscarinic acetylcholine receptors via their allosteric binding sites - Jakubik_1996_Proc.Natl.Acad.Sci.U.S.A_93_8705 |
| Author(s) : Jakubik J , Bacakova L , Lisa V , El-Fakahany EE , Tucek S |
| Ref : Proc Natl Acad Sci U S A , 93 :8705 , 1996 |
| Abstract : Jakubik_1996_Proc.Natl.Acad.Sci.U.S.A_93_8705 |
| ESTHER : Jakubik_1996_Proc.Natl.Acad.Sci.U.S.A_93_8705 |
| PubMedSearch : Jakubik_1996_Proc.Natl.Acad.Sci.U.S.A_93_8705 |
| PubMedID: 8710935 |
| Title : Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors - Jakubik_1995_J.Pharmacol.Exp.Ther_274_1077 |
| Author(s) : Jakubik J , Bacakova L , El-Fakahany EE , Tucek S |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 274 :1077 , 1995 |
| Abstract : Jakubik_1995_J.Pharmacol.Exp.Ther_274_1077 |
| ESTHER : Jakubik_1995_J.Pharmacol.Exp.Ther_274_1077 |
| PubMedSearch : Jakubik_1995_J.Pharmacol.Exp.Ther_274_1077 |
| PubMedID: 7562472 |
| Title : Positive allosteric interactions on cardiac muscarinic receptors: effects of chemical modifications of disulphide and carboxyl groups - Jakubik_1995_Eur.J.Pharmacol_289_311 |
| Author(s) : Jakubik J , Tucek S |
| Ref : European Journal of Pharmacology , 289 :311 , 1995 |
| Abstract : Jakubik_1995_Eur.J.Pharmacol_289_311 |
| ESTHER : Jakubik_1995_Eur.J.Pharmacol_289_311 |
| PubMedSearch : Jakubik_1995_Eur.J.Pharmacol_289_311 |
| PubMedID: 7621905 |