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References (19)

Title : Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans - Olfson_2016_Mol.Psychiatry_21_601
Author(s) : Olfson E , Saccone NL , Johnson EO , Chen LS , Culverhouse R , Doheny K , Foltz SM , Fox L , Gogarten SM , Hartz S , Hetrick K , Laurie CC , Marosy B , Amin N , Arnett D , Barr RG , Bartz TM , Bertelsen S , Borecki IB , Brown MR , Chasman DI , van Duijn CM , Feitosa MF , Fox ER , Franceschini N , Franco OH , Grove ML , Guo X , Hofman A , Kardia SL , Morrison AC , Musani SK , Psaty BM , Rao DC , Reiner AP , Rice K , Ridker PM , Rose LM , Schick UM , Schwander K , Uitterlinden AG , Vojinovic D , Wang JC , Ware EB , Wilson G , Yao J , Zhao W , Breslau N , Hatsukami D , Stitzel JA , Rice J , Goate A , Bierut LJ
Ref : Mol Psychiatry , 21 :601 , 2016
Abstract : Olfson_2016_Mol.Psychiatry_21_601
ESTHER : Olfson_2016_Mol.Psychiatry_21_601
PubMedSearch : Olfson_2016_Mol.Psychiatry_21_601
PubMedID: 26239294

Title : CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis - Chen_2015_J.Natl.Cancer.Inst_107_
Author(s) : Chen LS , Hung RJ , Baker T , Horton A , Culverhouse R , Saccone N , Cheng I , Deng B , Han Y , Hansen HM , Horsman J , Kim C , Lutz S , Rosenberger A , Aben KK , Andrew AS , Breslau N , Chang SC , Dieffenbach AK , Dienemann H , Frederiksen B , Han J , Hatsukami DK , Johnson EO , Pande M , Wrensch MR , McLaughlin J , Skaug V , van der Heijden HF , Wampfler J , Wenzlaff A , Woll P , Zienolddiny S , Bickeboller H , Brenner H , Duell EJ , Haugen A , Heinrich J , Hokanson JE , Hunter DJ , Kiemeney LA , Lazarus P , Le Marchand L , Liu G , Mayordomo J , Risch A , Schwartz AG , Teare D , Wu X , Wiencke JK , Yang P , Zhang ZF , Spitz MR , Kraft P , Amos CI , Bierut LJ
Ref : J Natl Cancer Inst , 107 : , 2015
Abstract : Chen_2015_J.Natl.Cancer.Inst_107_
ESTHER : Chen_2015_J.Natl.Cancer.Inst_107_
PubMedSearch : Chen_2015_J.Natl.Cancer.Inst_107_
PubMedID: 25873736

Title : Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence - Hancock_2015_Transl.Psychiatry_5_e651
Author(s) : Hancock DB , Reginsson GW , Gaddis NC , Chen X , Saccone NL , Lutz SM , Qaiser B , Sherva R , Steinberg S , Zink F , Stacey SN , Glasheen C , Chen J , Gu F , Frederiksen BN , Loukola A , Gudbjartsson DF , Bruske I , Landi MT , Bickeboller H , Madden P , Farrer L , Kaprio J , Kranzler HR , Gelernter J , Baker TB , Kraft P , Amos CI , Caporaso NE , Hokanson JE , Bierut LJ , Thorgeirsson TE , Johnson EO , Stefansson K
Ref : Transl Psychiatry , 5 :e651 , 2015
Abstract : Hancock_2015_Transl.Psychiatry_5_e651
ESTHER : Hancock_2015_Transl.Psychiatry_5_e651
PubMedSearch : Hancock_2015_Transl.Psychiatry_5_e651
PubMedID: 26440539

Title : A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence - Hancock_2015_Hum.Mol.Genet_24_5940
Author(s) : Hancock DB , Wang JC , Gaddis NC , Levy JL , Saccone NL , Stitzel JA , Goate A , Bierut LJ , Johnson EO
Ref : Hum Mol Genet , 24 :5940 , 2015
Abstract : Hancock_2015_Hum.Mol.Genet_24_5940
ESTHER : Hancock_2015_Hum.Mol.Genet_24_5940
PubMedSearch : Hancock_2015_Hum.Mol.Genet_24_5940
PubMedID: 26220977

Title : Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans - Culverhouse_2014_Addiction_109_814
Author(s) : Culverhouse RC , Johnson EO , Breslau N , Hatsukami DK , Sadler B , Brooks AI , Hesselbrock VM , Schuckit MA , Tischfield JA , Goate AM , Saccone NL , Bierut LJ
Ref : Addiction , 109 :814 , 2014
Abstract : Culverhouse_2014_Addiction_109_814
ESTHER : Culverhouse_2014_Addiction_109_814
PubMedSearch : Culverhouse_2014_Addiction_109_814
PubMedID: 24401102

Title : Distinct loci in the CHRNA5\/CHRNA3\/CHRNB4 gene cluster are associated with onset of regular smoking - Stephens_2013_Genet.Epidemiol_37_846
Author(s) : Stephens SH , Hartz SM , Hoft NR , Saccone NL , Corley RC , Hewitt JK , Hopfer CJ , Breslau N , Coon H , Chen X , Ducci F , Dueker N , Franceschini N , Frank J , Han Y , Hansel NN , Jiang C , Korhonen T , Lind PA , Liu J , Lyytikainen LP , Michel M , Shaffer JR , Short SE , Sun J , Teumer A , Thompson JR , Vogelzangs N , Vink JM , Wenzlaff A , Wheeler W , Yang BZ , Aggen SH , Balmforth AJ , Baumeister SE , Beaty TH , Benjamin DJ , Bergen AW , Broms U , Cesarini D , Chatterjee N , Chen J , Cheng YC , Cichon S , Couper D , Cucca F , Dick D , Foroud T , Furberg H , Giegling I , Gillespie NA , Gu F , Hall AS , Hallfors J , Han S , Hartmann AM , Heikkila K , Hickie IB , Hottenga JJ , Jousilahti P , Kaakinen M , Kahonen M , Koellinger PD , Kittner S , Konte B , Landi MT , Laatikainen T , Leppert M , Levy SM , Mathias RA , McNeil DW , Medland SE , Montgomery GW , Murray T , Nauck M , North KE , Pare PD , Pergadia M , Ruczinski I , Salomaa V , Viikari J , Willemsen G , Barnes KC , Boerwinkle E , Boomsma DI , Caporaso N , Edenberg HJ , Francks C , Gelernter J , Grabe HJ , Hops H , Jarvelin MR , Johannesson M , Kendler KS , Lehtimaki T , Magnusson PK , Marazita ML , Marchini J , Mitchell BD , Nothen MM , Penninx BW , Raitakari O , Rietschel M , Rujescu D , Samani NJ , Schwartz AG , Shete S , Spitz M , Swan GE , Volzke H , Veijola J , Wei Q , Amos C , Cannon DS , Grucza R , Hatsukami D , Heath A , Johnson EO , Kaprio J , Madden P , Martin NG , Stevens VL , Weiss RB , Kraft P , Bierut LJ , Ehringer MA
Ref : Genet Epidemiol , 37 :846 , 2013
Abstract : Stephens_2013_Genet.Epidemiol_37_846
ESTHER : Stephens_2013_Genet.Epidemiol_37_846
PubMedSearch : Stephens_2013_Genet.Epidemiol_37_846
PubMedID: 24186853

Title : Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers - Hartz_2012_Arch.Gen.Psychiatry_69_854
Author(s) : Hartz SM , Short SE , Saccone NL , Culverhouse R , Chen L , Schwantes-An TH , Coon H , Han Y , Stephens SH , Sun J , Chen X , Ducci F , Dueker N , Franceschini N , Frank J , Geller F , Gubjartsson D , Hansel NN , Jiang C , Keskitalo-Vuokko K , Liu Z , Lyytikainen LP , Michel M , Rawal R , Rosenberger A , Scheet P , Shaffer JR , Teumer A , Thompson JR , Vink JM , Vogelzangs N , Wenzlaff AS , Wheeler W , Xiao X , Yang BZ , Aggen SH , Balmforth AJ , Baumeister SE , Beaty T , Bennett S , Bergen AW , Boyd HA , Broms U , Campbell H , Chatterjee N , Chen J , Cheng YC , Cichon S , Couper D , Cucca F , Dick DM , Foroud T , Furberg H , Giegling I , Gu F , Hall AS , Hallfors J , Han S , Hartmann AM , Hayward C , Heikkila K , Hewitt JK , Hottenga JJ , Jensen MK , Jousilahti P , Kaakinen M , Kittner SJ , Konte B , Korhonen T , Landi MT , Laatikainen T , Leppert M , Levy SM , Mathias RA , McNeil DW , Medland SE , Montgomery GW , Muley T , Murray T , Nauck M , North K , Pergadia M , Polasek O , Ramos EM , Ripatti S , Risch A , Ruczinski I , Rudan I , Salomaa V , Schlessinger D , Styrkarsdottir U , Terracciano A , Uda M , Willemsen G , Wu X , Abecasis G , Barnes K , Bickeboller H , Boerwinkle E , Boomsma DI , Caporaso N , Duan J , Edenberg HJ , Francks C , Gejman PV , Gelernter J , Grabe HJ , Hops H , Jarvelin MR , Viikari J , Kahonen M , Kendler KS , Lehtimaki T , Levinson DF , Marazita ML , Marchini J , Melbye M , Mitchell BD , Murray JC , Nothen MM , Penninx BW , Raitakari O , Rietschel M , Rujescu D , Samani NJ , Sanders AR , Schwartz AG , Shete S , Shi J , Spitz M , Stefansson K , Swan GE , Thorgeirsson T , Volzke H , Wei Q , Wichmann HE , Amos CI , Breslau N , Cannon DS , Ehringer M , Grucza R , Hatsukami D , Heath A , Johnson EO , Kaprio J , Madden P , Martin NG , Stevens VL , Stitzel JA , Weiss RB , Kraft P , Bierut LJ
Ref : Arch Gen Psychiatry , 69 :854 , 2012
Abstract : Hartz_2012_Arch.Gen.Psychiatry_69_854
ESTHER : Hartz_2012_Arch.Gen.Psychiatry_69_854
PubMedSearch : Hartz_2012_Arch.Gen.Psychiatry_69_854
PubMedID: 22868939

Title : Dissection of the phenotypic and genotypic associations with nicotinic dependence - Chen_2012_Nicotine.Tob.Res_14_425
Author(s) : Chen LS , Baker TB , Grucza R , Wang JC , Johnson EO , Breslau N , Hatsukami D , Smith SS , Saccone NL , Saccone S , Rice JP , Goate AM , Bierut LJ
Ref : Nicotine Tob Res , 14 :425 , 2012
Abstract : Chen_2012_Nicotine.Tob.Res_14_425
ESTHER : Chen_2012_Nicotine.Tob.Res_14_425
PubMedSearch : Chen_2012_Nicotine.Tob.Res_14_425
PubMedID: 22102629

Title : Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success - Chen_2012_Am.J.Psychiatry_169_735
Author(s) : Chen LS , Baker TB , Piper ME , Breslau N , Cannon DS , Doheny KF , Gogarten SM , Johnson EO , Saccone NL , Wang JC , Weiss RB , Goate AM , Bierut LJ
Ref : Am J Psychiatry , 169 :735 , 2012
Abstract : Chen_2012_Am.J.Psychiatry_169_735
ESTHER : Chen_2012_Am.J.Psychiatry_169_735
PubMedSearch : Chen_2012_Am.J.Psychiatry_169_735
PubMedID: 22648373

Title : Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes - Chen_2012_Drug.Alcohol.Depend_123 Suppl 1_S42
Author(s) : Chen LS , Xian H , Grucza RA , Saccone NL , Wang JC , Johnson EO , Breslau N , Hatsukami D , Bierut LJ
Ref : Drug Alcohol Depend , 123 Suppl 1 :S42 , 2012
Abstract : Chen_2012_Drug.Alcohol.Depend_123 Suppl 1_S42
ESTHER : Chen_2012_Drug.Alcohol.Depend_123 Suppl 1_S42
PubMedSearch : Chen_2012_Drug.Alcohol.Depend_123 Suppl 1_S42
PubMedID: 22336398

Title : CHRNB3 is more strongly associated with Fagerstrom test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results - Rice_2012_Addiction_107_2019
Author(s) : Rice JP , Hartz SM , Agrawal A , Almasy L , Bennett S , Breslau N , Bucholz KK , Doheny KF , Edenberg HJ , Goate AM , Hesselbrock V , Howells WB , Johnson EO , Kramer J , Krueger RF , Kuperman S , Laurie C , Manolio TA , Neuman RJ , Nurnberger JI , Porjesz B , Pugh E , Ramos EM , Saccone NL , Saccone S , Schuckit M , Bierut LJ
Ref : Addiction , 107 :2019 , 2012
Abstract : Rice_2012_Addiction_107_2019
ESTHER : Rice_2012_Addiction_107_2019
PubMedSearch : Rice_2012_Addiction_107_2019
PubMedID: 22524403

Title : Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans - Saccone_2010_Genes.Brain.Behav_9_741
Author(s) : Saccone NL , Schwantes-An TH , Wang JC , Grucza RA , Breslau N , Hatsukami D , Johnson EO , Rice JP , Goate AM , Bierut LJ
Ref : Genes Brain Behav , 9 :741 , 2010
Abstract : Saccone_2010_Genes.Brain.Behav_9_741
ESTHER : Saccone_2010_Genes.Brain.Behav_9_741
PubMedSearch : Saccone_2010_Genes.Brain.Behav_9_741
PubMedID: 20584212

Title : Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes - Grucza_2010_Addict.Biol_15_346
Author(s) : Grucza RA , Johnson EO , Krueger RF , Breslau N , Saccone NL , Chen LS , Derringer J , Agrawal A , Lynskey M , Bierut LJ
Ref : Addict Biol , 15 :346 , 2010
Abstract : Grucza_2010_Addict.Biol_15_346
ESTHER : Grucza_2010_Addict.Biol_15_346
PubMedSearch : Grucza_2010_Addict.Biol_15_346
PubMedID: 20624154

Title : Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence - Johnson_2010_Addiction_105_2014
Author(s) : Johnson EO , Chen LS , Breslau N , Hatsukami D , Robbins T , Saccone NL , Grucza RA , Bierut LJ
Ref : Addiction , 105 :2014 , 2010
Abstract : Johnson_2010_Addiction_105_2014
ESTHER : Johnson_2010_Addiction_105_2014
PubMedSearch : Johnson_2010_Addiction_105_2014
PubMedID: 20840187

Title : Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes - Saccone_2009_Am.J.Med.Genet.B.Neuropsychiatr.Genet_150B_453
Author(s) : Saccone NL , Saccone SF , Hinrichs AL , Stitzel JA , Duan W , Pergadia ML , Agrawal A , Breslau N , Grucza RA , Hatsukami D , Johnson EO , Madden PA , Swan GE , Wang JC , Goate AM , Rice JP , Bierut LJ
Ref : American Journal of Medicine Genet B Neuropsychiatr Genet , 150B :453 , 2009
Abstract : Saccone_2009_Am.J.Med.Genet.B.Neuropsychiatr.Genet_150B_453
ESTHER : Saccone_2009_Am.J.Med.Genet.B.Neuropsychiatr.Genet_150B_453
PubMedSearch : Saccone_2009_Am.J.Med.Genet.B.Neuropsychiatr.Genet_150B_453
PubMedID: 19259974

Title : The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans - Saccone_2009_Cancer.Res_69_6848
Author(s) : Saccone NL , Wang JC , Breslau N , Johnson EO , Hatsukami D , Saccone SF , Grucza RA , Sun L , Duan W , Budde J , Culverhouse RC , Fox L , Hinrichs AL , Steinbach JH , Wu M , Rice JP , Goate AM , Bierut LJ
Ref : Cancer Research , 69 :6848 , 2009
Abstract : Saccone_2009_Cancer.Res_69_6848
ESTHER : Saccone_2009_Cancer.Res_69_6848
PubMedSearch : Saccone_2009_Cancer.Res_69_6848
PubMedID: 19706762

Title : Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerstrom Test for Nicotine Dependence - Agrawal_2009_Addiction_104_471
Author(s) : Agrawal A , Pergadia ML , Balasubramanian S , Saccone SF , Hinrichs AL , Saccone NL , Breslau N , Johnson EO , Hatsukami D , Martin NG , Montgomery GW , Goate AM , Rice JP , Bierut LJ , Madden PA
Ref : Addiction , 104 :471 , 2009
Abstract : Agrawal_2009_Addiction_104_471
ESTHER : Agrawal_2009_Addiction_104_471
PubMedSearch : Agrawal_2009_Addiction_104_471
PubMedID: 19207358

Title : Variants in nicotinic receptors and risk for nicotine dependence - Bierut_2008_Am.J.Psychiatry_165_1163
Author(s) : Bierut LJ , Stitzel JA , Wang JC , Hinrichs AL , Grucza RA , Xuei X , Saccone NL , Saccone SF , Bertelsen S , Fox L , Horton WJ , Breslau N , Budde J , Cloninger CR , Dick DM , Foroud T , Hatsukami D , Hesselbrock V , Johnson EO , Kramer J , Kuperman S , Madden PA , Mayo K , Nurnberger J, Jr. , Pomerleau O , Porjesz B , Reyes O , Schuckit M , Swan G , Tischfield JA , Edenberg HJ , Rice JP , Goate AM
Ref : Am J Psychiatry , 165 :1163 , 2008
Abstract : Bierut_2008_Am.J.Psychiatry_165_1163
ESTHER : Bierut_2008_Am.J.Psychiatry_165_1163
PubMedSearch : Bierut_2008_Am.J.Psychiatry_165_1163
PubMedID: 18519524

Title : Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs - Saccone_2007_Hum.Mol.Genet_16_36
Author(s) : Saccone SF , Hinrichs AL , Saccone NL , Chase GA , Konvicka K , Madden PA , Breslau N , Johnson EO , Hatsukami D , Pomerleau O , Swan GE , Goate AM , Rutter J , Bertelsen S , Fox L , Fugman D , Martin NG , Montgomery GW , Wang JC , Ballinger DG , Rice JP , Bierut LJ
Ref : Hum Mol Genet , 16 :36 , 2007
Abstract : Saccone_2007_Hum.Mol.Genet_16_36
ESTHER : Saccone_2007_Hum.Mol.Genet_16_36
PubMedSearch : Saccone_2007_Hum.Mol.Genet_16_36
PubMedID: 17135278