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| Title : 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia - Anandan_2011_Bioorg.Med.Chem.Lett_21_983 |
| Author(s) : Anandan SK , Webb HK , Chen D , Wang YX , Aavula BR , Cases S , Cheng Y , Do ZN , Mehra U , Tran V , Vincelette J , Waszczuk J , White K , Wong KR , Zhang LN , Jones PD , Hammock BD , Patel DV , Whitcomb R , MacIntyre DE , Sabry J , Gless R |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :983 , 2011 |
| Abstract : Anandan_2011_Bioorg.Med.Chem.Lett_21_983 |
| ESTHER : Anandan_2011_Bioorg.Med.Chem.Lett_21_983 |
| PubMedSearch : Anandan_2011_Bioorg.Med.Chem.Lett_21_983 |
| PubMedID: 21211973 |
| Title : Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs - Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| Author(s) : Tsai HJ , Hwang SH , Morisseau C , Yang J , Jones PD , Kasagami T , Kim IH , Hammock BD |
| Ref : Eur J Pharm Sci , 40 :222 , 2010 |
| Abstract : Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| ESTHER : Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| PubMedSearch : Tsai_2010_Eur.J.Pharm.Sci_40_222 |
| PubMedID: 20359531 |
| Title : 1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain - Rose_2010_J.Med.Chem_53_7067 |
| Author(s) : Rose TE , Morisseau C , Liu JY , Inceoglu B , Jones PD , Sanborn JR , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 53 :7067 , 2010 |
| Abstract : Rose_2010_J.Med.Chem_53_7067 |
| ESTHER : Rose_2010_J.Med.Chem_53_7067 |
| PubMedSearch : Rose_2010_J.Med.Chem_53_7067 |
| PubMedID: 20812725 |
| Title : Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation - Liu_2009_Br.J.Pharmacol_156_284 |
| Author(s) : Liu JY , Tsai HJ , Hwang SH , Jones PD , Morisseau C , Hammock BD |
| Ref : British Journal of Pharmacology , 156 :284 , 2009 |
| Abstract : Liu_2009_Br.J.Pharmacol_156_284 |
| ESTHER : Liu_2009_Br.J.Pharmacol_156_284 |
| PubMedSearch : Liu_2009_Br.J.Pharmacol_156_284 |
| PubMedID: 19154430 |
| Title : Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH) - Wheelock_2008_Bioorg.Med.Chem_16_2114 |
| Author(s) : Wheelock CE , Nishi K , Ying A , Jones PD , Colvin ME , Olmstead MM , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry , 16 :2114 , 2008 |
| Abstract : Wheelock_2008_Bioorg.Med.Chem_16_2114 |
| ESTHER : Wheelock_2008_Bioorg.Med.Chem_16_2114 |
| PubMedSearch : Wheelock_2008_Bioorg.Med.Chem_16_2114 |
| PubMedID: 18023188 |
| Title : Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules - Harris_2008_Arch.Biochem.Biophys_472_139 |
| Author(s) : Harris TR , Aronov PA , Jones PD , Tanaka H , Arand M , Hammock BD |
| Ref : Archives of Biochemistry & Biophysics , 472 :139 , 2008 |
| Abstract : Harris_2008_Arch.Biochem.Biophys_472_139 |
| ESTHER : Harris_2008_Arch.Biochem.Biophys_472_139 |
| PubMedSearch : Harris_2008_Arch.Biochem.Biophys_472_139 |
| PubMedID: 18267101 |
| Gene_locus related to this paper: caeel-K07C5.5 |
| Title : Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds - Wadkins_2007_Mol.Pharmacol_71_713 |
| Author(s) : Wadkins RM , Hyatt JL , Edwards CC , Tsurkan L , Redinbo MR , Wheelock CE , Jones PD , Hammock BD , Potter PM |
| Ref : Molecular Pharmacology , 71 :713 , 2007 |
| Abstract : Wadkins_2007_Mol.Pharmacol_71_713 |
| ESTHER : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedSearch : Wadkins_2007_Mol.Pharmacol_71_713 |
| PubMedID: 17167034 |
| Title : Development of a high-throughput screen for soluble epoxide hydrolase inhibition - Wolf_2006_Anal.Biochem_355_71 |
| Author(s) : Wolf NM , Morisseau C , Jones PD , Hock B , Hammock BD |
| Ref : Analytical Biochemistry , 355 :71 , 2006 |
| Abstract : Wolf_2006_Anal.Biochem_355_71 |
| ESTHER : Wolf_2006_Anal.Biochem_355_71 |
| PubMedSearch : Wolf_2006_Anal.Biochem_355_71 |
| PubMedID: 16729954 |
| Title : Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos - Wheelock_2005_Aquat.Toxicol_74_172 |
| Author(s) : Wheelock CE , Eder KJ , Werner I , Huang H , Jones PD , Brammell BF , Elskus AA , Hammock BD |
| Ref : Aquat Toxicol , 74 :172 , 2005 |
| Abstract : Wheelock_2005_Aquat.Toxicol_74_172 |
| ESTHER : Wheelock_2005_Aquat.Toxicol_74_172 |
| PubMedSearch : Wheelock_2005_Aquat.Toxicol_74_172 |
| PubMedID: 16011852 |
| Title : Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes - Stok_2004_J.Biol.Chem_279_29863 |
| Author(s) : Stok JE , Huang H , Jones PD , Wheelock CE , Morisseau C , Hammock BD |
| Ref : Journal of Biological Chemistry , 279 :29863 , 2004 |
| Abstract : Stok_2004_J.Biol.Chem_279_29863 |
| ESTHER : Stok_2004_J.Biol.Chem_279_29863 |
| PubMedSearch : Stok_2004_J.Biol.Chem_279_29863 |
| PubMedID: 15123619 |
| Gene_locus related to this paper: mouse-Ces2a , mouse-Ces2e |