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Author Report for: Khosla C

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    Title: Mapping the catalytic conformations of an assembly-line polyketide synthase module
    Cogan DP, Zhang K, Li X, Li S, Pintilie GD, Roh SH, Craik CS, Chiu W, Khosla C
    Ref: Science, 374:729, 2021 : PubMed

            

    Title: Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module
    Li X, Sevillano N, La Greca F, Deis L, Liu YC, Deller MC, Mathews, II, Matsui T, Cane DE and Khosla C <1 more author(s)>
    Ref: Journal of the American Chemical Society, 140:6518, 2018 : PubMed

            

    Title: Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase
    Li X, Sevillano N, La Greca F, Hsu J, Mathews, II, Matsui T, Craik CS, Khosla C
    Ref: Biochemistry, 57:6201, 2018 : PubMed

            

    Title: Prolyl endopeptidases
    Gass J, Khosla C
    Ref: Cell Mol Life Sciences, 64:345, 2007 : PubMed

            

    Title: Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity
    Shan L, Mathews, II, Khosla C
    Ref: Proc Natl Acad Sci U S A, 102:3599, 2005 : PubMed

            

    Title: A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases
    Hu Z, Pfeifer BA, Chao E, Murli S, Kealey J, Carney JR, Ashley G, Khosla C, Hutchinson CR
    Ref: Microbiology, 149:2213, 2003 : PubMed

            

    Title: Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase
    Yin Y, Lu H, Khosla C, Cane DE
    Ref: Journal of the American Chemical Society, 125:5671, 2003 : PubMed

            

    Title: Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases
    Tsai SC, Lu H, Cane DE, Khosla C, Stroud RM
    Ref: Biochemistry, 41:12598, 2002 : PubMed

            

    Title: Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster
    Chiu HT, Hubbard BK, Shah AN, Eide J, Fredenburg RA, Walsh CT, Khosla C
    Ref: Proc Natl Acad Sci U S A, 98:8548, 2001 : PubMed

            

    Title: Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel
    Tsai SC, Miercke LJ, Krucinski J, Gokhale R, Chen JC, Foster PG, Cane DE, Khosla C, Stroud RM
    Ref: Proc Natl Acad Sci U S A, 98:14808, 2001 : PubMed

            

    Title: Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum
    Julien B, Shah S, Ziermann R, Goldman R, Katz L, Khosla C
    Ref: Gene, 249:153, 2000 : PubMed

            

    Title: Cloning and heterologous expression of the epothilone gene cluster
    Tang L, Shah S, Chung L, Carney J, Katz L, Khosla C, Julien B
    Ref: Science, 287:640, 2000 : PubMed

            


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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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