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| Title : Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors - Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| Author(s) : Takahashi J , Hijikuro I , Kihara T , Murugesh MG , Fuse S , Kunimoto R , Tsumura Y , Akaike A , Niidome T , Okuno Y , Takahashi T , Sugimoto H |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1718 , 2010 |
| Abstract : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| ESTHER : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| PubMedSearch : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1718 |
| PubMedID: 20137934 |
| Title : Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of alpha7 nicotinic receptors and internalization of NMDA receptors - Shen_2010_Br.J.Pharmacol_161_127 |
| Author(s) : Shen H , Kihara T , Hongo H , Wu X , Kem WR , Shimohama S , Akaike A , Niidome T , Sugimoto H |
| Ref : British Journal of Pharmacology , 161 :127 , 2010 |
| Abstract : Shen_2010_Br.J.Pharmacol_161_127 |
| ESTHER : Shen_2010_Br.J.Pharmacol_161_127 |
| PubMedSearch : Shen_2010_Br.J.Pharmacol_161_127 |
| PubMedID: 20718745 |
| Title : Design, synthesis and evaluation of carbamate-modified (-)-N(1)-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors - Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| Author(s) : Takahashi J , Hijikuro I , Kihara T , Murugesh MG , Fuse S , Tsumura Y , Akaike A , Niidome T , Takahashi T , Sugimoto H |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1721 , 2010 |
| Abstract : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| ESTHER : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| PubMedSearch : Takahashi_2010_Bioorg.Med.Chem.Lett_20_1721 |
| PubMedID: 20137941 |
| Title : Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models - Takeuchi_2009_J.Neurosci.Res_87_576 |
| Author(s) : Takeuchi H , Yanagida T , Inden M , Takata K , Kitamura Y , Yamakawa K , Sawada H , Izumi Y , Yamamoto N , Kihara T , Uemura K , Inoue H , Taniguchi T , Akaike A , Takahashi R , Shimohama S |
| Ref : Journal of Neuroscience Research , 87 :576 , 2009 |
| Abstract : Takeuchi_2009_J.Neurosci.Res_87_576 |
| ESTHER : Takeuchi_2009_J.Neurosci.Res_87_576 |
| PubMedSearch : Takeuchi_2009_J.Neurosci.Res_87_576 |
| PubMedID: 18803299 |
| Title : Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe\/PS1dE9 mouse model of Alzheimer's disease - Goto_2008_Eur.J.Pharmacol_583_84 |
| Author(s) : Goto Y , Niidome T , Hongo H , Akaike A , Kihara T , Sugimoto H |
| Ref : European Journal of Pharmacology , 583 :84 , 2008 |
| Abstract : Goto_2008_Eur.J.Pharmacol_583_84 |
| ESTHER : Goto_2008_Eur.J.Pharmacol_583_84 |
| PubMedSearch : Goto_2008_Eur.J.Pharmacol_583_84 |
| PubMedID: 18282567 |
| Title : Stimulation of nicotinic acetylcholine receptors protects motor neurons - Nakamizo_2005_Biochem.Biophys.Res.Commun_330_1285 |
| Author(s) : Nakamizo T , Kawamata J , Yamashita H , Kanki R , Kihara T , Sawada H , Akaike A , Shimohama S |
| Ref : Biochemical & Biophysical Research Communications , 330 :1285 , 2005 |
| Abstract : Nakamizo_2005_Biochem.Biophys.Res.Commun_330_1285 |
| ESTHER : Nakamizo_2005_Biochem.Biophys.Res.Commun_330_1285 |
| PubMedSearch : Nakamizo_2005_Biochem.Biophys.Res.Commun_330_1285 |
| PubMedID: 15823582 |
| Title : Alzheimer's disease and acetylcholine receptors - Kihara_2004_Acta.Neurobiol.Exp.(Wars)_64_99 |
| Author(s) : Kihara T , Shimohama S |
| Ref : Acta Neurobiol Exp (Wars) , 64 :99 , 2004 |
| Abstract : Kihara_2004_Acta.Neurobiol.Exp.(Wars)_64_99 |
| ESTHER : Kihara_2004_Acta.Neurobiol.Exp.(Wars)_64_99 |
| PubMedSearch : Kihara_2004_Acta.Neurobiol.Exp.(Wars)_64_99 |
| PubMedID: 15190684 |
| Title : alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity - Kihara_2001_J.Biol.Chem_276_13541 |
| Author(s) : Kihara T , Shimohama S , Sawada H , Honda K , Nakamizo T , Shibasaki H , Kume T , Akaike A |
| Ref : Journal of Biological Chemistry , 276 :13541 , 2001 |
| Abstract : Kihara_2001_J.Biol.Chem_276_13541 |
| ESTHER : Kihara_2001_J.Biol.Chem_276_13541 |
| PubMedSearch : Kihara_2001_J.Biol.Chem_276_13541 |
| PubMedID: 11278378 |
| Title : Stimulation of alpha4beta2 nicotinic acetylcholine receptors inhibits beta-amyloid toxicity - Kihara_1998_Brain.Res_792_331 |
| Author(s) : Kihara T , Shimohama S , Urushitani M , Sawada H , Kimura J , Kume T , Maeda T , Akaike A |
| Ref : Brain Research , 792 :331 , 1998 |
| Abstract : Kihara_1998_Brain.Res_792_331 |
| ESTHER : Kihara_1998_Brain.Res_792_331 |
| PubMedSearch : Kihara_1998_Brain.Res_792_331 |
| PubMedID: 9593977 |
| Title : Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity - Kihara_1997_Ann.Neurol_42_159 |
| Author(s) : Kihara T , Shimohama S , Sawada H , Kimura J , Kume T , Kochiyama H , Maeda T , Akaike A |
| Ref : Annals of Neurology , 42 :159 , 1997 |
| Abstract : Kihara_1997_Ann.Neurol_42_159 |
| ESTHER : Kihara_1997_Ann.Neurol_42_159 |
| PubMedSearch : Kihara_1997_Ann.Neurol_42_159 |
| PubMedID: 9266724 |