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| Title : Pharmacokinetic modeling and [(1)(2)(3)]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089 - Chin_2011_J.Pharmacol.Exp.Ther_336_716 |
| Author(s) : Chin CL , Carr RA , Llano DA , Barret O , Xu H , Batis J , Koren AO , Seibyl JP , Marsh KC , Tamagnan G , Decker MW , Day M , Fox GB |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :716 , 2011 |
| Abstract : Chin_2011_J.Pharmacol.Exp.Ther_336_716 |
| ESTHER : Chin_2011_J.Pharmacol.Exp.Ther_336_716 |
| PubMedSearch : Chin_2011_J.Pharmacol.Exp.Ther_336_716 |
| PubMedID: 21172907 |
| Title : Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors - Brody_2006_Arch.Gen.Psychiatry_63_907 |
| Author(s) : Brody AL , Mandelkern MA , London ED , Olmstead RE , Farahi J , Scheibal D , Jou J , Allen V , Tiongson E , Chefer SI , Koren AO , Mukhin AG |
| Ref : Arch Gen Psychiatry , 63 :907 , 2006 |
| Abstract : Brody_2006_Arch.Gen.Psychiatry_63_907 |
| ESTHER : Brody_2006_Arch.Gen.Psychiatry_63_907 |
| PubMedSearch : Brody_2006_Arch.Gen.Psychiatry_63_907 |
| PubMedID: 16894067 |
| Title : Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography - Vaupel_2005_J.Pharmacol.Exp.Ther_312_355 |
| Author(s) : Vaupel DB , Tella SR , Huso DL , Wagner VO, 3rd , Mukhin AG , Chefer SI , Horti AG , London ED , Koren AO , Kimes AS |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 312 :355 , 2005 |
| Abstract : Vaupel_2005_J.Pharmacol.Exp.Ther_312_355 |
| ESTHER : Vaupel_2005_J.Pharmacol.Exp.Ther_312_355 |
| PubMedSearch : Vaupel_2005_J.Pharmacol.Exp.Ther_312_355 |
| PubMedID: 15331657 |
| Title : In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors - Gundisch_2005_Synapse_55_89 |
| Author(s) : Gundisch D , Koren AO , Horti AG , Pavlova OA , Kimes AS , Mukhin AG , London ED |
| Ref : Synapse , 55 :89 , 2005 |
| Abstract : Gundisch_2005_Synapse_55_89 |
| ESTHER : Gundisch_2005_Synapse_55_89 |
| PubMedSearch : Gundisch_2005_Synapse_55_89 |
| PubMedID: 15529332 |
| Title : Whole-body radiation dosimetry of 2-[18F]Fluoro-A-85380 in human PET imaging studies - Obrzut_2005_Nucl.Med.Biol_32_869 |
| Author(s) : Obrzut SL , Koren AO , Mandelkern MA , Brody AL , Hoh CK , London ED |
| Ref : Nucl Med Biol , 32 :869 , 2005 |
| Abstract : Obrzut_2005_Nucl.Med.Biol_32_869 |
| ESTHER : Obrzut_2005_Nucl.Med.Biol_32_869 |
| PubMedSearch : Obrzut_2005_Nucl.Med.Biol_32_869 |
| PubMedID: 16253812 |
| Title : Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior - King_2003_J.Neurosci_23_3837 |
| Author(s) : King SL , Marks MJ , Grady SR , Caldarone BJ , Koren AO , Mukhin AG , Collins AC , Picciotto MR |
| Ref : Journal of Neuroscience , 23 :3837 , 2003 |
| Abstract : King_2003_J.Neurosci_23_3837 |
| ESTHER : King_2003_J.Neurosci_23_3837 |
| PubMedSearch : King_2003_J.Neurosci_23_3837 |
| PubMedID: 12736354 |
| Title : 2-[18F]F-A-85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans - Kimes_2003_FASEB.J_17_1331 |
| Author(s) : Kimes AS , Horti AG , London ED , Chefer SI , Contoreggi C , Ernst M , Friello P , Koren AO , Kurian V , Matochik JA , Pavlova O , Vaupel DB , Mukhin AG |
| Ref : FASEB Journal , 17 :1331 , 2003 |
| Abstract : Kimes_2003_FASEB.J_17_1331 |
| ESTHER : Kimes_2003_FASEB.J_17_1331 |
| PubMedSearch : Kimes_2003_FASEB.J_17_1331 |
| PubMedID: 12759330 |
| Title : Self-administration of 5-iodo-A-85380, a beta2-selective nicotinic receptor ligand, by operantly trained rats - Liu_2003_Neuroreport_14_1503 |
| Author(s) : Liu X , Koren AO , Yee SK , Pechnick RN , Poland RE , London ED |
| Ref : Neuroreport , 14 :1503 , 2003 |
| Abstract : Liu_2003_Neuroreport_14_1503 |
| ESTHER : Liu_2003_Neuroreport_14_1503 |
| PubMedSearch : Liu_2003_Neuroreport_14_1503 |
| PubMedID: 12960773 |
| Title : Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET - Fujita_2003_Eur.J.Nucl.Med.Mol.Imaging_30_1620 |
| Author(s) : Fujita M , Ichise M , van Dyck CH , Zoghbi SS , Tamagnan G , Mukhin AG , Bozkurt A , Seneca N , Tipre D , DeNucci CC , Iida H , Vaupel DB , Horti AG , Koren AO , Kimes AS , London ED , Seibyl JP , Baldwin RM , Innis RB |
| Ref : Eur J Nucl Med Mol Imaging , 30 :1620 , 2003 |
| Abstract : Fujita_2003_Eur.J.Nucl.Med.Mol.Imaging_30_1620 |
| ESTHER : Fujita_2003_Eur.J.Nucl.Med.Mol.Imaging_30_1620 |
| PubMedSearch : Fujita_2003_Eur.J.Nucl.Med.Mol.Imaging_30_1620 |
| PubMedID: 14523584 |
| Title : Graphical analysis of 2-[18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain - Chefer_2003_Synapse_48_25 |
| Author(s) : Chefer SI , London ED , Koren AO , Pavlova OA , Kurian V , Kimes AS , Horti AG , Mukhin AG |
| Ref : Synapse , 48 :25 , 2003 |
| Abstract : Chefer_2003_Synapse_48_25 |
| ESTHER : Chefer_2003_Synapse_48_25 |
| PubMedSearch : Chefer_2003_Synapse_48_25 |
| PubMedID: 12557269 |
| Title : 6-[18F]Fluoro-A-85380: an in vivo tracer for the nicotinic acetylcholine receptor - Scheffel_2000_Nucl.Med.Biol_27_51 |
| Author(s) : Scheffel U , Horti AG , Koren AO , Ravert HT , Banta JP , Finley PA , London ED , Dannals RF |
| Ref : Nucl Med Biol , 27 :51 , 2000 |
| Abstract : Scheffel_2000_Nucl.Med.Biol_27_51 |
| ESTHER : Scheffel_2000_Nucl.Med.Biol_27_51 |
| PubMedSearch : Scheffel_2000_Nucl.Med.Biol_27_51 |
| PubMedID: 10755645 |
| Title : Development of ligands for in vivo imaging of cerebral nicotinic receptors - Sihver_2000_Behav.Brain.Res_113_143 |
| Author(s) : Sihver W , Nordberg A , Langstrom B , Mukhin AG , Koren AO , Kimes AS , London ED |
| Ref : Behavioural Brain Research , 113 :143 , 2000 |
| Abstract : Sihver_2000_Behav.Brain.Res_113_143 |
| ESTHER : Sihver_2000_Behav.Brain.Res_113_143 |
| PubMedSearch : Sihver_2000_Behav.Brain.Res_113_143 |
| PubMedID: 10942041 |
| Title : 6-[18F]fluoro-A-85380, a novel radioligand for in vivo imaging of central nicotinic acetylcholine receptors - Horti_2000_Life.Sci_67_463 |
| Author(s) : Horti AG , Chefer SI , Mukhin AG , Koren AO , Gundisch D , Links JM , Kurian V , Dannals RF , London ED |
| Ref : Life Sciences , 67 :463 , 2000 |
| Abstract : Horti_2000_Life.Sci_67_463 |
| ESTHER : Horti_2000_Life.Sci_67_463 |
| PubMedSearch : Horti_2000_Life.Sci_67_463 |
| PubMedID: 11003056 |
| Title : 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors - Mukhin_2000_Mol.Pharmacol_57_642 |
| Author(s) : Mukhin AG , Gundisch D , Horti AG , Koren AO , Tamagnan G , Kimes AS , Chambers J , Vaupel DB , King SL , Picciotto MR , Innis RB , London ED |
| Ref : Molecular Pharmacology , 57 :642 , 2000 |
| Abstract : Mukhin_2000_Mol.Pharmacol_57_642 |
| ESTHER : Mukhin_2000_Mol.Pharmacol_57_642 |
| PubMedSearch : Mukhin_2000_Mol.Pharmacol_57_642 |
| PubMedID: 10692507 |
| Title : Synthesis and characterization of binding of 5-[76Br]bromo-3-[[2(S)-azetidinyl]methoxy]pyridine, a novel nicotinic acetylcholine receptor ligand, in rat brain - Sihver_1999_J.Neurochem_73_1264 |
| Author(s) : Sihver W , Fasth KJ , Horti AG , Koren AO , Bergstrom M , Lu L , Hagberg G , Lundqvist H , Dannals RF , London ED , Nordberg A , Langstrom B |
| Ref : Journal of Neurochemistry , 73 :1264 , 1999 |
| Abstract : Sihver_1999_J.Neurochem_73_1264 |
| ESTHER : Sihver_1999_J.Neurochem_73_1264 |
| PubMedSearch : Sihver_1999_J.Neurochem_73_1264 |
| PubMedID: 10461920 |
| Title : 2-[18F]F-A-85380: a PET radioligand for alpha4beta2 nicotinic acetylcholine receptors - Chefer_1999_Neuroreport_10_2715 |
| Author(s) : Chefer SI , Horti AG , Koren AO , Gundisch D , Links JM , Kurian V , Dannals RF , Mukhin AG , London ED |
| Ref : Neuroreport , 10 :2715 , 1999 |
| Abstract : Chefer_1999_Neuroreport_10_2715 |
| ESTHER : Chefer_1999_Neuroreport_10_2715 |
| PubMedSearch : Chefer_1999_Neuroreport_10_2715 |
| PubMedID: 10511429 |
| Title : Radiosynthesis and preliminary evaluation of 5-[123\/125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine: a radioligand for nicotinic acetylcholine receptors - Horti_1999_Nucl.Med.Biol_26_175 |
| Author(s) : Horti AG , Koren AO , Lee KS , Mukhin AG , Vaupel DB , Kimes AS , Stratton M , London ED |
| Ref : Nucl Med Biol , 26 :175 , 1999 |
| Abstract : Horti_1999_Nucl.Med.Biol_26_175 |
| ESTHER : Horti_1999_Nucl.Med.Biol_26_175 |
| PubMedSearch : Horti_1999_Nucl.Med.Biol_26_175 |
| PubMedID: 10100216 |
| Title : 2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling - Koren_1998_J.Med.Chem_41_3690 |
| Author(s) : Koren AO , Horti AG , Mukhin AG , Gundisch D , Kimes AS , Dannals RF , London ED |
| Ref : Journal of Medicinal Chemistry , 41 :3690 , 1998 |
| Abstract : Koren_1998_J.Med.Chem_41_3690 |
| ESTHER : Koren_1998_J.Med.Chem_41_3690 |
| PubMedSearch : Koren_1998_J.Med.Chem_41_3690 |
| PubMedID: 9733494 |
| Title : In vivo studies with [125I]5-I-A-85380, a nicotinic acetylcholine receptor radioligand - Vaupel_1998_Neuroreport_9_2311 |
| Author(s) : Vaupel DB , Mukhin AG , Kimes AS , Horti AG , Koren AO , London ED |
| Ref : Neuroreport , 9 :2311 , 1998 |
| Abstract : Vaupel_1998_Neuroreport_9_2311 |
| ESTHER : Vaupel_1998_Neuroreport_9_2311 |
| PubMedSearch : Vaupel_1998_Neuroreport_9_2311 |
| PubMedID: 9694220 |
| Title : In vivo imaging of brain nicotinic acetylcholine receptors with 5-[123I]iodo-A-85380 using single photon emission computed tomography - Chefer_1998_Life.Sci_63_PL355 |
| Author(s) : Chefer SI , Horti AG , Lee KS , Koren AO , Jones DW , Gorey JG , Links JM , Mukhin AG , Weinberger DR , London ED |
| Ref : Life Sciences , 63 :PL355 , 1998 |
| Abstract : Chefer_1998_Life.Sci_63_PL355 |
| ESTHER : Chefer_1998_Life.Sci_63_PL355 |
| PubMedSearch : Chefer_1998_Life.Sci_63_PL355 |
| PubMedID: 9870715 |
| Title : 2-[18F]Fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors - Horti_1998_Nucl.Med.Biol_25_599 |
| Author(s) : Horti AG , Scheffel U , Koren AO , Ravert HT , Mathews WB , Musachio JL , Finley PA , London ED , Dannals RF |
| Ref : Nucl Med Biol , 25 :599 , 1998 |
| Abstract : Horti_1998_Nucl.Med.Biol_25_599 |
| ESTHER : Horti_1998_Nucl.Med.Biol_25_599 |
| PubMedSearch : Horti_1998_Nucl.Med.Biol_25_599 |
| PubMedID: 9804040 |