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| Title : 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases - Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| Author(s) : Knez D , Diez-Iriepa D , Chioua M , Gottinger A , Denic M , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Meden A , Pislar A , Kos J , Zakelj S , Stojan J , Salat K , Serrano J , Patricia Fernandez AP , Sanchez-Garcia A , Martinez-Murillo R , Binda C , Lopez-Munoz F , Gobec S , Marco-Contelle J |
| Ref : Acta Pharmaceutica Sinica B , 13 :2152 , 2023 |
| Abstract : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| ESTHER : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| PubMedSearch : Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152 |
| PubMedID: 37250172 |
| Gene_locus related to this paper: human-BCHE |
| Title : Lysosomal peptidases - Intriguing roles in cancer progression and neurodegeneration - Kos_2022_FEBS.Open.Bio__ |
| Author(s) : Kos J , Mitrovic A , Perisic Nanut M , Pislar A |
| Ref : FEBS Open Bio , : , 2022 |
| Abstract : Kos_2022_FEBS.Open.Bio__ |
| ESTHER : Kos_2022_FEBS.Open.Bio__ |
| PubMedSearch : Kos_2022_FEBS.Open.Bio__ |
| PubMedID: 35067006 |
| Title : Synthesis and Hybrid SAR Property Modeling of Novel Cholinesterase Inhibitors - Kos_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Kos J , Kozik V , Pindjakova D , Jankech T , Smolinski A , Stepankova S , Hosek J , Oravec M , Jampilek J , Bak A |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : Kos_2021_Int.J.Mol.Sci_22_ |
| ESTHER : Kos_2021_Int.J.Mol.Sci_22_ |
| PubMedSearch : Kos_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33810550 |
| Title : N-alkylpiperidine carbamates as potential anti-Alzheimer's agents - Kosak_2020_Eur.J.Med.Chem_197_112282 |
| Author(s) : Kosak U , Strasek N , Knez N , Jukic M , Zakelj S , Zahirovic A , Pislar A , Brazzolotto X , Nachon F , Kos J , Gobec S , Knez D |
| Ref : Eur Journal of Medicinal Chemistry , 197 :112282 , 2020 |
| Abstract : Kosak_2020_Eur.J.Med.Chem_197_112282 |
| ESTHER : Kosak_2020_Eur.J.Med.Chem_197_112282 |
| PubMedSearch : Kosak_2020_Eur.J.Med.Chem_197_112282 |
| PubMedID: 32380361 |
| Gene_locus related to this paper: human-BCHE |
| Title : Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease - Meden_2019_Chem.Commun.(Camb)_55_3765 |
| Author(s) : Meden A , Knez D , Jukic M , Brazzolotto X , Grsic M , Pislar A , Zahirovic A , Kos J , Nachon F , Svete J , Gobec S , Groselj U |
| Ref : Chem Commun (Camb) , 55 :3765 , 2019 |
| Abstract : Meden_2019_Chem.Commun.(Camb)_55_3765 |
| ESTHER : Meden_2019_Chem.Commun.(Camb)_55_3765 |
| PubMedSearch : Meden_2019_Chem.Commun.(Camb)_55_3765 |
| PubMedID: 30864579 |
| Gene_locus related to this paper: human-BCHE |
| Title : SAR-mediated Similarity Assessment of the Property Profile for New, Silicon-Based AChE\/BChE Inhibitors - Bak_2019_Int.J.Mol.Sci_20_5385 |
| Author(s) : Bak A , Pizova H , Kozik V , Vorcakova K , Kos J , Treml J , Odehnalova K , Oravec M , Imramovsky A , Bobal P , Smolinski A , Travnicek Z , Jampilek J |
| Ref : Int J Mol Sci , 20 :5385 , 2019 |
| Abstract : Bak_2019_Int.J.Mol.Sci_20_5385 |
| ESTHER : Bak_2019_Int.J.Mol.Sci_20_5385 |
| PubMedSearch : Bak_2019_Int.J.Mol.Sci_20_5385 |
| PubMedID: 31671776 |
| Title : Biological Evaluation of 8-Hydroxyquinolines as Multi-Target Directed Ligands for Treating Alzheimer's Disease - Knez_2019_Curr.Alzheimer.Res_16_801 |
| Author(s) : Knez D , Sosic I , Pislar A , Mitrovic A , Jukic M , Kos J , Gobec S |
| Ref : Curr Alzheimer Res , 16 :801 , 2019 |
| Abstract : Knez_2019_Curr.Alzheimer.Res_16_801 |
| ESTHER : Knez_2019_Curr.Alzheimer.Res_16_801 |
| PubMedSearch : Knez_2019_Curr.Alzheimer.Res_16_801 |
| PubMedID: 31660830 |
| Title : Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities - Knez_2018_Eur.J.Med.Chem_156_598 |
| Author(s) : Knez D , Coquelle N , Pislar A , Zakelj S , Jukic M , Sova M , Mravljak J , Nachon F , Brazzolotto X , Kos J , Colletier JP , Gobec S |
| Ref : Eur Journal of Medicinal Chemistry , 156 :598 , 2018 |
| Abstract : Knez_2018_Eur.J.Med.Chem_156_598 |
| ESTHER : Knez_2018_Eur.J.Med.Chem_156_598 |
| PubMedSearch : Knez_2018_Eur.J.Med.Chem_156_598 |
| PubMedID: 30031971 |
| Gene_locus related to this paper: human-BCHE |
| Title : The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity - Kosak_2018_J.Med.Chem_61_119 |
| Author(s) : Kosak U , Brus B , Knez D , Zakelj S , Trontelj J , Pislar A , Sink R , Jukic M , Zivin M , Podkowa A , Nachon F , Brazzolotto X , Stojan J , Kos J , Coquelle N , Salat K , Colletier JP , Gobec S |
| Ref : Journal of Medicinal Chemistry , 61 :119 , 2018 |
| Abstract : Kosak_2018_J.Med.Chem_61_119 |
| ESTHER : Kosak_2018_J.Med.Chem_61_119 |
| PubMedSearch : Kosak_2018_J.Med.Chem_61_119 |
| PubMedID: 29227101 |
| Gene_locus related to this paper: human-BCHE |
| Title : Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents - Panek_2018_ACS.Chem.Neurosci_9_1074 |
| Author(s) : Panek D , Wieckowska A , Jonczyk J , Godyn J , Bajda M , Wichur T , Pasieka A , Knez D , Pislar A , Korabecny J , Soukup O , Sepsova V , Sabate R , Kos J , Gobec S , Malawska B |
| Ref : ACS Chem Neurosci , 9 :1074 , 2018 |
| Abstract : Panek_2018_ACS.Chem.Neurosci_9_1074 |
| ESTHER : Panek_2018_ACS.Chem.Neurosci_9_1074 |
| PubMedSearch : Panek_2018_ACS.Chem.Neurosci_9_1074 |
| PubMedID: 29345897 |
| Title : N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents - Kosak_2017_Bioorg.Med.Chem_25_633 |
| Author(s) : Kosak U , Knez D , Coquelle N , Brus B , Pislar A , Nachon F , Brazzolotto X , Kos J , Colletier JP , Gobec S |
| Ref : Bioorganic & Medicinal Chemistry , 25 :633 , 2017 |
| Abstract : Kosak_2017_Bioorg.Med.Chem_25_633 |
| ESTHER : Kosak_2017_Bioorg.Med.Chem_25_633 |
| PubMedSearch : Kosak_2017_Bioorg.Med.Chem_25_633 |
| PubMedID: 27908752 |
| Gene_locus related to this paper: human-BCHE |
| Title : Development of an in-vivo active reversible butyrylcholinesterase inhibitor - Kosak_2016_Sci.Rep_6_39495 |
| Author(s) : Kosak U , Brus B , Knez D , Sink R , Zakelj S , Trontelj J , Pislar A , Slenc J , Gobec M , Zivin M , Tratnjek L , Perse M , Salat K , Podkowa A , Filipek B , Nachon F , Brazzolotto X , Wieckowska A , Malawska B , Stojan J , Rascan IM , Kos J , Coquelle N , Colletier JP , Gobec S |
| Ref : Sci Rep , 6 :39495 , 2016 |
| Abstract : Kosak_2016_Sci.Rep_6_39495 |
| ESTHER : Kosak_2016_Sci.Rep_6_39495 |
| PubMedSearch : Kosak_2016_Sci.Rep_6_39495 |
| PubMedID: 28000737 |
| Gene_locus related to this paper: human-BCHE |
| Title : Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and beta-amyloid aggregation inhibitors with neuroprotective properties - Guzior_2015_Eur.J.Med.Chem_92C_738 |
| Author(s) : Guzior N , Bajda M , Skrok M , Kurpiewska K , Lewinski K , Brus B , Pislar A , Kos J , Gobec S , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 92C :738 , 2015 |
| Abstract : Guzior_2015_Eur.J.Med.Chem_92C_738 |
| ESTHER : Guzior_2015_Eur.J.Med.Chem_92C_738 |
| PubMedSearch : Guzior_2015_Eur.J.Med.Chem_92C_738 |
| PubMedID: 25621991 |
| Title : Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor - Brus_2014_J.Med.Chem_57_8167 |
| Author(s) : Brus B , Kosak U , Turk S , Pislar A , Coquelle N , Kos J , Stojan J , Colletier JP , Gobec S |
| Ref : Journal of Medicinal Chemistry , 57 :8167 , 2014 |
| Abstract : Brus_2014_J.Med.Chem_57_8167 |
| ESTHER : Brus_2014_J.Med.Chem_57_8167 |
| PubMedSearch : Brus_2014_J.Med.Chem_57_8167 |
| PubMedID: 25226236 |
| Gene_locus related to this paper: human-BCHE |