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| Title : Identification of (R)-[(18)F]YH134 for Monoacylglycerol Lipase Neuroimaging and Exploration of Its Use for Central Nervous System and Peripheral Drug Development - He_2023_J.Nucl.Med__ |
| Author(s) : He Y , Kramer SD , Grether U , Wittwer MB , Collin L , Kuhn B , Topp A , Heer D , O'Hara F , Honer M , Pavlovic A , Richter H , Ritter M , Rombach D , Keller C , Gobbi L , Mu L |
| Ref : J Nucl Med , : , 2023 |
| Abstract : He_2023_J.Nucl.Med__ |
| ESTHER : He_2023_J.Nucl.Med__ |
| PubMedSearch : He_2023_J.Nucl.Med__ |
| PubMedID: 38164615 |
| Title : A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature - Kemble_2022_PLoS.One_17_e0268590 |
| Author(s) : Kemble AM , Hornsperger B , Ruf I , Richter H , Benz J , Kuhn B , Heer D , Wittwer M , Engelhardt B , Grether U , Collin L |
| Ref : PLoS ONE , 17 :e0268590 , 2022 |
| Abstract : Kemble_2022_PLoS.One_17_e0268590 |
| ESTHER : Kemble_2022_PLoS.One_17_e0268590 |
| PubMedSearch : Kemble_2022_PLoS.One_17_e0268590 |
| PubMedID: 36084029 |
| Gene_locus related to this paper: human-MGLL |
| Title : Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold - He_2022_Nucl.Med.Biol_108-109_24 |
| Author(s) : He Y , Gobbi LC , Herde AM , Rombach D , Ritter M , Kuhn B , Wittwer MB , Heer D , Hornsperger B , Bell C , O'Hara F , Benz J , Honer M , Keller C , Collin L , Richter H , Schibli R , Grether U , Mu L |
| Ref : Nucl Med Biol , 108-109 :24 , 2022 |
| Abstract : He_2022_Nucl.Med.Biol_108-109_24 |
| ESTHER : He_2022_Nucl.Med.Biol_108-109_24 |
| PubMedSearch : He_2022_Nucl.Med.Biol_108-109_24 |
| PubMedID: 35248850 |
| Title : Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging - He_2022_J.Med.Chem_65_2191 |
| Author(s) : He Y , Schild M , Grether U , Benz J , Leibrock L , Heer D , Topp A , Collin L , Kuhn B , Wittwer M , Keller C , Gobbi LC , Schibli R , Mu L |
| Ref : Journal of Medicinal Chemistry , 65 :2191 , 2022 |
| Abstract : He_2022_J.Med.Chem_65_2191 |
| ESTHER : He_2022_J.Med.Chem_65_2191 |
| PubMedSearch : He_2022_J.Med.Chem_65_2191 |
| PubMedID: 35089028 |
| Gene_locus related to this paper: human-MGLL |
| Title : Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors - Boehringer_2010_Bioorg.Med.Chem.Lett_20_1106 |
| Author(s) : Boehringer M , Fischer H , Hennig M , Hunziker D , Huwyler J , Kuhn B , Loeffler BM , Luebbers T , Mattei P , Narquizian R , Sebokova E , Sprecher U , Wessel HP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1106 , 2010 |
| Abstract : Boehringer_2010_Bioorg.Med.Chem.Lett_20_1106 |
| ESTHER : Boehringer_2010_Bioorg.Med.Chem.Lett_20_1106 |
| PubMedSearch : Boehringer_2010_Bioorg.Med.Chem.Lett_20_1106 |
| PubMedID: 20031408 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of carmegliptin: a potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| Author(s) : Mattei P , Boehringer M , Di Giorgio P , Fischer H , Hennig M , Huwyler J , Kocer B , Kuhn B , Loeffler BM , Macdonald A , Narquizian R , Rauber E , Sebokova E , Sprecher U |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1109 , 2010 |
| Abstract : Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| ESTHER : Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| PubMedSearch : Mattei_2010_Bioorg.Med.Chem.Lett_20_1109 |
| PubMedID: 20031405 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Molecular recognition of ligands in dipeptidyl peptidase IV - Kuhn_2007_Curr.Top.Med.Chem_7_609 |
| Author(s) : Kuhn B , Hennig M , Mattei P |
| Ref : Curr Top Med Chem , 7 :609 , 2007 |
| Abstract : Kuhn_2007_Curr.Top.Med.Chem_7_609 |
| ESTHER : Kuhn_2007_Curr.Top.Med.Chem_7_609 |
| PubMedSearch : Kuhn_2007_Curr.Top.Med.Chem_7_609 |
| PubMedID: 17352681 |
| Title : 1,3-disubstituted 4-aminopiperidines as useful tools in the optimization of the 2-aminobenzo[a]quinolizine dipeptidyl peptidase IV inhibitors - Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| Author(s) : Lubbers T , Bohringer M , Gobbi L , Hennig M , Hunziker D , Kuhn B , Loffler B , Mattei P , Narquizian R , Peters JU , Ruff Y , Wessel HP , Wyss P |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :2966 , 2007 |
| Abstract : Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| ESTHER : Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| PubMedSearch : Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| PubMedID: 17418568 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Aminomethylpyrimidines as novel DPP-IV inhibitors: a 10(5)-fold activity increase by optimization of aromatic substituents - Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
| Author(s) : Peters JU , Weber S , Kritter S , Weiss P , Wallier A , Boehringer M , Hennig M , Kuhn B , Loeffler BM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1491 , 2004 |
| Abstract : Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
| ESTHER : Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
| PubMedSearch : Peters_2004_Bioorg.Med.Chem.Lett_14_1491 |
| PubMedID: 15006388 |
| Gene_locus related to this paper: human-DPP4 |