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Author Report for: Kumar A

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    Title: Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship
    Abdullaha M, Banoo R, Nuthakki VK, Sharma M, Kaur S, Thakur S, Kumar A, Jadhav HR, Bharate SB
    Ref: ACS Omega, 8:17591, 2023 : PubMed


    Title: Cell wall and immune modulation by Rv1800 (PPE28) helps M. smegmatis to evade intracellular killing
    Anand PK, Saini V, Kaur J, Kumar A
    Ref: Int J Biol Macromol, :125837, 2023 : PubMed


    Title: Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer's Disease
    Bhanukiran K, Singh SK, Singh R, Kumar A, Hemalatha S
    Ref: ACS Chem Neurosci, :, 2023 : PubMed


    Title: The role of astrocytic alpha7 nicotinic acetylcholine receptors in Alzheimer disease
    Fontana IC, Kumar A, Nordberg A
    Ref: Nat Rev Neurol, :, 2023 : PubMed


    Title: Adsorption Characterization of Lactobacillus sp. for Di-(2-ethylhexyl) phthalate
    Goyal SP, Agarwal T, Mishra V, Kumar A, Saravanan C
    Ref: Probiotics Antimicrob Proteins, :, 2023 : PubMed


    Title: Ameliorating the Role of Aripiprazole in Memory Deficits Induced by Intracerebroventricular Streptozotocin-Induced Dementia of Alzheimer's Type
    Gupta T, Singh V, Hefnawy M, Alanazi MM, Alsuwayt B, Kabra A, Kumar A, Pasricha C, Singh R
    Ref: ACS Omega, 8:25295, 2023 : PubMed


    Title: Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease
    Gutti G, Leifeld J, Kakarla R, Bajad NG, Ganeshpurkar A, Kumar A, Krishnamurthy S, Klein-Schmidt C, Tapken D and Singh SK <1 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 259:115670, 2023 : PubMed


    Title: Industrial applications of fungal lipases: a review
    Kumar A, Verma V, Dubey VK, Srivastava A, Garg SK, Singh VP, Arora PK
    Ref: Front Microbiol, 14:1142536, 2023 : PubMed


    Title: Effect of Curcumin and Coenzyme Q10 Alone and in Combination on Learning and Memory in an Animal Model of Alzheimer's Disease
    Kumar P, Singh A, Kumar A, Kumar R, Pal R, Sachan AK, Dixit RK, Nath R
    Ref: Biomedicines, 11:, 2023 : PubMed


    Title: Targeting DPP4-RBD interactions by sitagliptin and linagliptin delivers a potential host-directed therapy against pan-SARS-CoV-2 infections
    Mani S, Kaur A, Jakhar K, Kumari G, Sonar S, Kumar A, Das S, Kumar S, Kumar V and Majumdar T <3 more author(s)>
    Ref: Int J Biol Macromol, 245:125444, 2023 : PubMed


    Title: Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448
    Nuthakki VK, Choudhary S, Reddy CN, Bhatt S, Jamwal A, Jotshi A, Raghuvanshi R, Sharma A, Thakur S and Bharate SB <4 more author(s)>
    Ref: ACS Chem Neurosci, :, 2023 : PubMed


    Title: Structure-based Virtual Screening and Molecular Dynamic Simulation Approach for the Identification of Terpenoids as Potential DPP-4 Inhibitors
    P AA, Kumar A, Jangid K, Kumar V, Jaitak V
    Ref: Curr Comput Aided Drug Des, :, 2023 : PubMed


    Title: Exploring Potent Fungal Isolates from Sanitary Landfill Soil for In Vitro Degradation of Dibutyl Phthalate
    Puranik S, Shukla L, Kundu A, Kamil D, Paul S, Venkadasamy G, Salim R, Singh SK, Kumar D, Kumar A
    Ref: J Fungi (Basel), 9:, 2023 : PubMed


    Title: 2D-QSAR, molecular docking and MD simulation based virtual screening of the herbal molecules against Alzheimer's disorder: an approach to predict CNS activity
    Thakur A, Sharma B, Parashar A, Sharma V, Kumar A, Mehta V
    Ref: J Biomol Struct Dyn, :1, 2023 : PubMed


    Title: A Mild Dose of Aspirin Promotes Hippocampal Neurogenesis and Working Memory in Experimental Ageing Mice
    Vergil Andrews JF, Selvaraj DB, Kumar A, Roshan SA, Anusuyadevi M, Kandasamy M
    Ref: Brain Sci, 13:, 2023 : PubMed


    Title: Environment dependent expression of mycobacterium hormone sensitive lipases: expression pattern under ex-vivo and individual in-vitro stress conditions in M. tuberculosis H37Ra
    Arya S, Singh P, Kaur J, Kumar A
    Ref: Mol Biol Rep, :, 2022 : PubMed


    Title: Structural Insight of New Butyrylcholinesterase Inhibitors Based on Benzylbenzofuran Scaffold
    Delogu GL, Fais A, Pintus F, Goyal C, Matos MJ, Era B, Kumar A
    Ref: Pharmaceuticals (Basel), 15:, 2022 : PubMed


    Title: Identification of sulfonamide based butyrylcholinesterase inhibitors through scaffold hopping approach
    Ganeshpurkar A, Singh R, Kumar D, Gore P, Shivhare S, Sardana D, Rayala S, Kumar A, Singh SK
    Ref: Int J Biol Macromol, :, 2022 : PubMed


    Title: Identification of sulfonamide-based butyrylcholinesterase inhibitors using machine learning
    Ganeshpurkar A, Singh R, Kumar D, Gutti G, Gore P, Sahu B, Kumar A, Singh SK
    Ref: Future Med Chem, :, 2022 : PubMed


    Title: Identification of potential AChE inhibitors through combined machine-learning and structure-based design approaches
    Ganeshpurkar A, Singh R, Singh RB, Kumar D, Kumar A, Singh SK
    Ref: Indian J Biochem Biophys, 59:619, 2022 : PubMed


    Title: Design, synthesis, extra-precision docking, and molecular dynamics simulation studies of pyrrolidin-2-one derivatives as potential acetylcholinesterase inhibitors
    Gupta M, Kumar A, Prasun C, Nair MS, Kini SG, Yadav D, Nain S
    Ref: J Biomol Struct Dyn, :1, 2022 : PubMed


    Title: A Recent Appraisal of Small-Organic Molecules as Anti-Alzheimer's Agents
    Gupta M, Kumar A, Ojha M, Khan SK, Nain S
    Ref: Mini Rev Med Chem, :, 2022 : PubMed


    Title: Dental pulp stem cell secretome ameliorates d-galactose induced accelerated aging in rat model
    Kumar A, Mahajan A, Kumari P, Singh J, Raik S, Saha L, Pal A, Medhi B, Rattan V, Bhattacharyya S
    Ref: Cell Biochemistry & Function, :, 2022 : PubMed


    Title: Recent advances in the development of nitrogen-containing heterocyclic Anti-Alzheimer's agents
    Kumar A, Nehra B, Singh D, Kuma D, Chawla PA
    Ref: Curr Top Med Chem, :, 2022 : PubMed


    Title: An overview of the pharmacological activities of scopoletin against different chronic diseases
    Parama D, Girisa S, Khatoon E, Kumar A, Alqahtani MS, Abbas M, Sethi G, Kunnumakkara AB
    Ref: Pharmacol Res, 179:106202, 2022 : PubMed


    Title: Recent advances in assessment methods and mechanism of microbe-mediated chlorpyrifos remediation
    Raj A, Kumar A
    Ref: Environ Research, :114011, 2022 : PubMed


    Title: Mixture toxicity assessment of selected insecticides to silver perch fingerling, Bidyanus bidyanus
    Arora S, Kumar A
    Ref: Ecotoxicology & Environmental Safety, 226:112790, 2021 : PubMed


    Title: A systematic review of carbohydrate-based bioactive molecules for Alzheimer's disease
    Bajad NG, Swetha R, Gutti G, Singh M, Kumar A, Singh SK
    Ref: Future Med Chem, :, 2021 : PubMed


    Title: Deciphering the Behavioral Response of Meloidogyne incognita and Fusarium oxysporum Toward Mustard Essential Oil
    Dutta A, Mandal A, Kundu A, Malik M, Chaudhary A, Khan MR, Shanmugam V, Rao U, Saha S and Singh A <5 more author(s)>
    Ref: Front Plant Sci, 12:714730, 2021 : PubMed


    Title: Identification of 1,2,4-triazolylthioethanone Scaffold for the Design of New Acetylcholinesterase Inhibitors
    Fatiha Muhammad E, Kumar A, Wahab HA, Zhang KYJ
    Ref: Mol Inform, :, 2021 : PubMed


    Title: Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
    Floris S, Fais A, Medda R, Pintus F, Piras A, Kumar A, Kus PM, Westermark GT, Era B
    Ref: J Enzyme Inhib Med Chem, 36:517, 2021 : PubMed


    Title: Improved machine learning scoring functions for identification of Electrophorus electricus's acetylcholinesterase inhibitors
    Ganeshpurkar A, Singh R, Shivhare S, Divya, Kumar D, Gutti G, Kumar A, Singh SK
    Ref: Mol Divers, :, 2021 : PubMed


    Title: Development of homology model, docking protocol and Machine-Learning based scoring functions for identification of Equus caballus's butyrylcholinesterase inhibitors
    Ganeshpurkar A, Singh R, Kumar D, Gutti G, Sardana D, Shivhare S, Singh RB, Kumar A, Singh SK
    Ref: J Biomol Struct Dyn, :1, 2021 : PubMed


    Title: Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity
    Kaur Gulati H, Choudhary S, Kumar N, Ahmed A, Bhagat K, Vir Singh J, Singh A, Kumar A, Singh Bedi PM and Mukherjee D <1 more author(s)>
    Ref: Bioorg Chem, 118:105479, 2021 : PubMed


    Title: Biomedical Implications of Plant-Based Principles as Antidepressants: Prospects for Novel Drug Development
    Khushboo, Kumar A, Sharma B
    Ref: Mini Rev Med Chem, :, 2021 : PubMed


    Title: Pancreatic lipase inhibitors: The road voyaged and successes
    Kumar A, Chauhan S
    Ref: Life Sciences, :119115, 2021 : PubMed


    Title: Arbutin attenuates monosodium L-glutamate induced neurotoxicity and cognitive dysfunction in rats
    Kumar M, Kumar A, Sindhu RK, Kushwah AS
    Ref: Neurochem Int, 151:105217, 2021 : PubMed


    Title: The lipolytic activity of LipJ, a stress-induced enzyme, is regulated by its C-terminal adenylate cyclase domain
    Kumari B, Kaur J, Maan P, Kumar A
    Ref: Future Microbiol, :, 2021 : PubMed


    Title: Partially saturated canthaxanthin alleviates aging-associated oxidative stress in D-galactose administered male wistar rats
    Mathimaran A, Kumar A, Prajapati G, Ampapathi RS, Bora HK, Guha R
    Ref: Biogerontology, 22:19, 2021 : PubMed


    Title: Pharmacological investigations on efficacy of Phlorizin a sodium-glucose co-transporter (SGLT) inhibitor in mouse model of intracerebroventricular streptozotocin induced dementia of AD type
    Rani R, Kumar A, Jaggi AS, Singh N
    Ref: J Basic Clin Physiol Pharmacol, :, 2021 : PubMed


    Title: Ameliorative role of rolipram, PDE-4 inhibitor, against sodium arsenite-induced vascular dementia in rats
    Virk D, Kumar A, Jaggi AS, Singh N
    Ref: Environ Sci Pollut Res Int, :, 2021 : PubMed


    Title: Discovery of a New Donepezil-like Acetylcholinesterase Inhibitor for Targeting Alzheimer's Disease: Computational Studies with Biological Validation
    Akhoon BA, Choudhary S, Tiwari H, Kumar A, Barik MR, Rathor L, Pandey R, Nargotra A
    Ref: J Chem Inf Model, 60:4717, 2020 : PubMed


    Title: Computational Studies on Acetylcholinesterase Inhibitors: From Biochemistry to Chemistry
    Bagri K, Kumar A, Manisha, Kumar P
    Ref: Mini Rev Med Chem, 20:1403, 2020 : PubMed


    Title: Characterization of the CAZy Repertoire from the Marine-Derived Fungus Stemphylium lucomagnoense in Relation to Saline Conditions
    Ben Ali W, Navarro D, Kumar A, Drula E, Turbe-Doan A, Correia LO, Baumberger S, Bertrand E, Faulds CB and Record E <3 more author(s)>
    Ref: Mar Drugs, 18:, 2020 : PubMed


    Title: Correlation and prognostic significance of serum amylase, serum lipase, and plasma cholinesterase in acute organophosphorus poisoning
    Dungdung A, Kumar A, Kumar B, Preetam M, Tara RK, Saba MK
    Ref: J Family Med Prim Care, 9:1873, 2020 : PubMed


    Title: Structural and functional insights about unique extremophilic bacterial lipolytic enzyme from metagenome source
    Kaur R, Kumar R, Verma S, Kumar A, Rajesh C, Sharma PK
    Ref: Int J Biol Macromol, :, 2020 : PubMed


    Title: Molecular dynamics assisted mechanistic insight of Val430-Ala mutation of Rv1592c protein in isoniazid resistant Mycobacterium tuberculosis
    Kumar A, Anand PK, Chandel S, Shrivatava A, Kaur J
    Ref: Curr Comput Aided Drug Des, :, 2020 : PubMed


    Title: A Broad Temperature Active Lipase Purified From a Psychrotrophic Bacterium of Sikkim Himalaya With Potential Application in Detergent Formulation
    Kumar A, Mukhia S, Kumar N, Acharya V, Kumar S, Kumar R
    Ref: Front Bioeng Biotechnol, 8:642, 2020 : PubMed


    Title: Aspergillus nidulans: A Potential Resource of the Production of the Native and Heterologous Enzymes for Industrial Applications
    Kumar A
    Ref: Int J Microbiol, 2020:8894215, 2020 : PubMed


    Title: Candida antarctica lipase-B-catalyzed kinetic resolution of 1,3-dialkyl-3-hydroxymethyl oxindoles
    Kumar N, Kumar A, Sahoo SC, Chimni SS
    Ref: Chirality, 32:1377, 2020 : PubMed


    Title: Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study
    Balkrishna A, Pokhrel S, Tomer M, Verma S, Kumar A, Nain P, Gupta A, Varshney A
    Ref: Molecules, 24:, 2019 : PubMed


    Title: Protein-Protein Interactions and Aggregation Inhibitors in Alzheimer's Disease
    Ganeshpurkar A, Swetha R, Kumar D, Gangaram GP, Singh R, Gutti G, Jana S, Kumar A, Singh SK
    Ref: Curr Top Med Chem, 19:501, 2019 : PubMed


    Title: Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer's disease
    Gutti G, Kumar D, Paliwal P, Ganeshpurkar A, Lahre K, Kumar A, Krishnamurthy S, Singh SK
    Ref: Bioorg Chem, 90:103080, 2019 : PubMed


    Title: Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease
    Gutti G, Kakarla R, Kumar D, Beohar M, Ganeshpurkar A, Kumar A, Krishnamurthy S, Singh SK
    Ref: Eur Journal of Medicinal Chemistry, 182:111613, 2019 : PubMed


    Title: Computational and In-Vitro Validation of Natural Molecules as Potential Acetylcholinesterase Inhibitors and Neuroprotective Agents
    Kumar A, Mehta V, Raj U, Varadwaj PK, Udayabanu M, Yennamalli RM, Singh TR
    Ref: Curr Alzheimer Res, 16:116, 2019 : PubMed


    Title: Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018)
    Mishra P, Kumar A, Panda G
    Ref: Bioorganic & Medicinal Chemistry, 27:895, 2019 : PubMed


    Title: Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors
    Nuthakki VK, Mudududdla R, Sharma A, Kumar A, Bharate SB
    Ref: Bioorg Chem, 90:103062, 2019 : PubMed


    Title: Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent
    Nuthakki VK, Sharma A, Kumar A, Bharate SB
    Ref: Drug Dev Res, 80:655, 2019 : PubMed


    Title: Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to these areas
    Sinclair LI, Kumar A, Darreh-Shori T, Love S
    Ref: Alzheimers Res Ther, 11:80, 2019 : PubMed


    Title: Targeting oxidative stress, acetylcholinesterase, proinflammatory cytokine, dopamine and GABA by eucalyptus oil (Eucalyptus globulus) to alleviate ketamine-induced psychosis in rats
    Yadav M, Jindal DK, Parle M, Kumar A, Dhingra S
    Ref: Inflammopharmacology, 27:301, 2019 : PubMed


    Title: Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms
    Yadav P, Goyal VD, Gaur NK, Kumar A, Gokhale SM, Jamdar SN, Makde RD
    Ref: Journal of Biological Chemistry, 294:89, 2019 : PubMed


    Title: Tramadol ameliorates behavioural, biochemical, mitochondrial and histological alterations in ICV-STZ-induced sporadic dementia of Alzheimer's type in rats
    Dhull DK, Kumar A
    Ref: Inflammopharmacology, 26:925, 2018 : PubMed


    Title: Synthesis, molecular docking and cholinesterase inhibitory activity of hydroxylated 2-phenylbenzofuran derivatives
    Fais A, Kumar A, Medda R, Pintus F, Delogu F, Matos MJ, Era B, Delogu GL
    Ref: Bioorg Chem, 84:302, 2018 : PubMed


    Title: Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer's disease
    Kumar A, Pintus F, Di Petrillo A, Medda R, Caria P, Matos MJ, Vina D, Pieroni E, Delogu F and Fais A <2 more author(s)>
    Ref: Sci Rep, 8:4424, 2018 : PubMed


    Title: Use of Simplified Molecular Input Line Entry System and molecular graph based descriptors in prediction and design of pancreatic lipase inhibitors
    Kumar A, Chauhan S
    Ref: Future Med Chem, 10:1603, 2018 : PubMed


    Title: Soluble Abeta42 Acts as Allosteric Activator of the Core Cholinergic Enzyme Choline Acetyltransferase
    Kumar A, Lana E, Kumar R, Lithner CU, Darreh-Shori T
    Ref: Front Mol Neurosci, 11:327, 2018 : PubMed


    Title: Rv1288, a Two Domain, Cell Wall Anchored, Nutrient Stress Inducible Carboxyl-Esterase of Mycobacterium tuberculosis, Modulates Cell Wall Lipid
    Maan P, Kumar A, Kaur J
    Ref: Front Cell Infect Microbiol, 8:421, 2018 : PubMed


    Title: Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations
    Mourya A, Akhtar A, Ahuja S, Sah SP, Kumar A
    Ref: European Journal of Pharmacology, 835:31, 2018 : PubMed


    Title: Neuromodulatory potential of phenylpropanoids; para-methoxycinnamic acid and ethyl-p-methoxycinnamate on aluminum-induced memory deficit in rats
    Rijal S, Changdar N, Kinra M, Kumar A, Nampoothiri M, Arora D, Shenoy RR, Pai KSR, Joseph A, Mudgal J
    Ref: Toxicol Mech Methods, :1, 2018 : PubMed


    Title: Binary combinations of organophosphorus and synthetic pyrethroids are more potent acetylcholinesterase inhibitors than organophosphorus and carbamate mixtures: An in vitro assessment
    Arora S, Balotra S, Pandey G, Kumar A
    Ref: Toxicol Lett, 268:8, 2017 : PubMed


    Title: Calcineurin inhibitors improve memory loss and neuropathological changes in mouse model of dementia
    Kumar A, Singh N
    Ref: Pharmacol Biochem Behav, 153:147, 2017 : PubMed


    Title: Inhibitor of Phosphodiestearse-4 improves memory deficits, oxidative stress, neuroinflammation and neuropathological alterations in mouse models of dementia of Alzheimer's Type
    Kumar A, Singh N
    Ref: Biomed Pharmacother, 88:698, 2017 : PubMed


    Title: Pharmacological activation of protein kinase A improves memory loss and neuropathological changes in a mouse model of dementia of Alzheimer's type
    Kumar A, Singh N
    Ref: Behav Pharmacol, 28:187, 2017 : PubMed


    Title: Rv0774c, an iron stress inducible, extracellular esterase is involved in immune-suppression associated with altered cytokine and TLR2 expression
    Kumar A, Singh SM, Singh R, Kaur J
    Ref: Int J Med Microbiol, 307:126, 2017 : PubMed


    Title: The immunosuppressive effects of a novel recombinant LipQ (Rv2485c) protein of Mycobacterium tuberculosis on human macrophage cell lines
    Kumar A, Manisha, Sangha GK, Shrivastava A, Kaur J
    Ref: Microb Pathog, 107:361, 2017 : PubMed


    Title: Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease
    Kumar K, Kumar A, Keegan RM, Deshmukh R
    Ref: Biomed Pharmacother, 98:297, 2017 : PubMed


    Title: DMSO: A Mixed-Competitive Inhibitor of Human Acetylcholinesterase
    Kumar A, Darreh-Shori T
    Ref: ACS Chem Neurosci, 8:2618, 2017 : PubMed


    Title: In-Silico Characterization of a Hypothetical Protein, Rv1288 of Mycobacterium tuberculosis Containing an Esterase Signature and an Uncommon LytE Domain
    Kumar A, Maan P, Singh G, Kaur J
    Ref: Curr Comput Aided Drug Des, 13:101, 2017 : PubMed


    Title: Inhibition of Aβ(1-42)Oligomerization, Fibrillization and Acetylcholinesterase Activity by Some Anti-Inflammatory Drugs: An in vitro Study
    Parmar HS, Assaiya A, Agrawal R, Tiwari S, Mufti I, Jain N, Manivannan E, Banerjee T, Kumar A
    Ref: Antiinflamm Antiallergy Agents Med Chem, 15:191, 2017 : PubMed


    Title: A Method for Isolation of Extracellular Vesicles and Characterization of Exosomes from Brain Extracellular Space
    Perez-Gonzalez R, Gauthier SA, Kumar A, Saito M, Levy E
    Ref: Methods Mol Biol, 1545:139, 2017 : PubMed


    Title: Quercetin along with piperine prevents cognitive dysfunction, oxidative stress and neuro-inflammation associated with mouse model of chronic unpredictable stress
    Rinwa P, Kumar A
    Ref: Arch Pharm Res, 40:1166, 2017 : PubMed


    Title: Galantamine attenuates N,N-dimethyl hydrazine induced neoplastic colon damage by inhibiting acetylcholinesterase and bimodal regulation of nicotinic cholinergic neurotransmission
    Sammi SR, Rawat JK, Raghav N, Kumar A, Roy S, Singh M, Gautam S, Yadav RK, Devi U and Kaithwas G <1 more author(s)>
    Ref: European Journal of Pharmacology, 818:174, 2017 : PubMed


    Title: Neuroprotective mechanism of Coenzyme Q10 (CoQ10) against PTZ induced kindling and associated cognitive dysfunction: Possible role of microglia inhibition
    Bhardwaj M, Kumar A
    Ref: Pharmacol Rep, 68:1301, 2016 : PubMed


    Title: 2-Phenylbenzofuran derivatives as butyrylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling
    Delogu GL, Matos MJ, Fanti M, Era B, Medda R, Pieroni E, Fais A, Kumar A, Pintus F
    Ref: Bioorganic & Medicinal Chemistry Lett, 26:2308, 2016 : PubMed


    Title: Effect of Capparis spinosa Linn. extract on lipopolysaccharide-induced cognitive impairment in rats
    Goel A, Digvijaya, Garg A, Kumar A
    Ref: Indian J Exp Biol, 54:126, 2016 : PubMed


    Title: Disruption of N terminus long range non covalent interactions shifted temp.opt 25 degrees C to cold: Evolution of point mutant Bacillus lipase by error prone PCR
    Goomber S, Kumar A, Kaur J
    Ref: Gene, 576:237, 2016 : PubMed


    Title: Point Mutation Ile137-Met Near Surface Conferred Psychrophilic Behaviour and Improved Catalytic Efficiency to Bacillus Lipase of 1.4 Subfamily
    Goomber S, Kumar A, Singh R, Kaur J
    Ref: Appl Biochem Biotechnol, 178:753, 2016 : PubMed


    Title: Computational modelling and protein-ligand interaction studies of SMlipA lipase cloned from forest metagenome
    Khan M, Kumar A
    Ref: J Mol Graph Model, 70:212, 2016 : PubMed


    Title: Lipase catalysis in organic solvents: advantages and applications
    Kumar A, Dhar K, Kanwar SS, Arora PK
    Ref: Biol Proced Online, 18:2, 2016 : PubMed


    Title: Functional characterization of hypothetical proteins of Mycobacterium tuberculosis with possible esterase/lipase signature: A Cumulative in silico and in vitro approach
    Kumar A, Sharma A, Kaur G, Makkar P, Kaur J
    Ref: J Biomol Struct Dyn, 35:1226, 2016 : PubMed


    Title: Possible neuroprotective mechanisms of clove oil against icv-colchicine induced cognitive dysfunction
    Kumar A, Aggrawal A, Pottabathini R, Singh A
    Ref: Pharmacol Rep, 68:764, 2016 : PubMed


    Title: Microbial degradation of 2,4-dichlorophenoxyacetic acid: Insight into the enzymes and catabolic genes involved, their regulation and biotechnological implications
    Kumar A, Trefault N, Olaniran AO
    Ref: Crit Rev Microbiol, 42:194, 2016 : PubMed


    Title: Immobilization of a novel cold active esterase onto FeO approximately cellulose nano-composite enhances catalytic properties
    Rahman MA, Culsum U, Kumar A, Gao H, Hu N
    Ref: Int J Biol Macromol, 87:488, 2016 : PubMed


    Title: Brain cholinergic alterations in rats subjected to repeated immobilization or forced swim stress on lambda-cyhalothrin exposure
    Shukla RK, Gupta R, Srivastava P, Dhuriya YK, Singh A, Chandravanshi LP, Kumar A, Siddiqui MH, Parmar D and Khanna VK <1 more author(s)>
    Ref: Neurochem Int, 93:51, 2016 : PubMed


    Title: Propensity of Withania somnifera to Attenuate Behavioural, Biochemical, and Histological Alterations in Experimental Model of Stroke
    Sood A, Kumar A, Dhawan DK, Sandhir R
    Ref: Cellular Molecular Neurobiology, 36:1123, 2016 : PubMed


    Title: Binary combinations of organophosphorus pesticides exhibit differential toxicity under oxidised and un-oxidised conditions
    Arora S, Kumar A
    Ref: Ecotoxicology & Environmental Safety, 115C:93, 2015 : PubMed


    Title: Evaluation of standardized Bacopa monniera extract in sodium fluoride-induced behavioural, biochemical, and histopathological alterations in mice
    Balaji B, Kumar EP, Kumar A
    Ref: Toxicol Ind Health, 31:18, 2015 : PubMed


    Title: A review on Alzheimer's disease pathophysiology and its management: an update
    Kumar A, Singh A, Ekavali
    Ref: Pharmacol Rep, 67:195, 2015 : PubMed


    Title: Effect of Licofelone-A Dual COX/5-LOX Inhibitor in Intracerebroventricular Streptozotocin-Induced Behavioral and Biochemical Abnormalities in Rats
    Kumar A, Sharma S, Prashar A, Deshmukh R
    Ref: Journal of Molecular Neuroscience, 55:749, 2015 : PubMed


    Title: Efficacy of Cilostazol a selective phosphodiesterase-3 inhibitor in rat model of Streptozotocin diabetes induced vascular dementia
    Kumar A, Jaggi AS, Singh N
    Ref: Pharmacol Biochem Behav, 135:20, 2015 : PubMed


    Title: Neuroprotective mechanism of losartan and its interaction with nimesulide against chronic fatigue stress
    Kumar A, Singh B, Mishra J, Sah SP, Pottabathini R
    Ref: Inflammopharmacology, 23:291, 2015 : PubMed


    Title: Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship
    Manda S, Sharma S, Wani A, Joshi P, Kumar V, Guru SK, Bharate SS, Bhushan S, Vishwakarma RA and Bharate SB <1 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 107:1, 2015 : PubMed


    Title: Neuroprotective effect of N-acetyl cysteine against streptozotocin-induced memory dysfunction and oxidative damage in rats
    Prakash A, Kalra JK, Kumar A
    Ref: J Basic Clin Physiol Pharmacol, 26:13, 2015 : PubMed


    Title: Microglial Inhibitory Mechanism of Coenzyme Q10 Against Abeta (1-42) Induced Cognitive Dysfunctions: Possible Behavioral, Biochemical, Cellular, and Histopathological Alterations
    Singh A, Kumar A
    Ref: Front Pharmacol, 6:268, 2015 : PubMed


    Title: Evaluation of Acute toxicity of Lambda Cyhalothrin in Mus musculus L
    Tomar M, Kumar A, Kataria SK
    Ref: Indian J Exp Biol, 53:551, 2015 : PubMed


    Title: A cold-adapted, solvent and salt tolerant esterase from marine bacterium Psychrobacter pacificensis
    Wu G, Zhang X, Wei L, Kumar A, Mao T, Liu Z
    Ref: Int J Biol Macromol, 81:180, 2015 : PubMed


    Title: Expression, purification, crystallization and preliminary X-ray diffraction analysis of acylpeptide hydrolase from Deinococcus radiodurans
    Are VN, Ghosh B, Kumar A, Yadav P, Bhatnagar D, Jamdar SN, Makde RD
    Ref: Acta Crystallographica F Struct Biol Commun, 70:1292, 2014 : PubMed


    Title: Mildronate improves cognition and reduces amyloid-beta pathology in transgenic Alzheimer's disease mice
    Beitnere U, van Groen T, Kumar A, Jansone B, Klusa V, Kadish I
    Ref: Journal of Neuroscience Research, 92:338, 2014 : PubMed


    Title: Cloning, expression, purification and three-dimensional structure prediction of haloalkane dehalogenase from a recently isolated Ancylobacter aquaticus strain UV5
    Kumar A, Pillay B, Olaniran AO
    Ref: Protein Expr Purif, 99C:10, 2014 : PubMed


    Title: Possible nitric oxide modulation in the protective effects of rutin against experimental head trauma-induced cognitive deficits: behavioral, biochemical, and molecular correlates
    Kumar A, Rinwa P, Dhar H
    Ref: J Surg Res, 188:268, 2014 : PubMed


    Title: Microglial inhibitory effect of ginseng ameliorates cognitive deficits and neuroinflammation following traumatic head injury in rats
    Kumar A, Rinwa P, Dhar H
    Ref: Inflammopharmacology, 22:155, 2014 : PubMed


    Title: Two structurally different dienelactone hydrolases (TfdEI and TfdEII) from Cupriavidus necator JMP134 plasmid pJP4 catalyse cis- and trans-dienelactones with similar efficiency
    Kumar A, Pillay B, Olaniran AO
    Ref: PLoS ONE, 9:e101801, 2014 : PubMed


    Title: In vivo protection of diisopropylphosphorofluoridate (DFP) poisoning by three bis-quaternary 2 -(hydroxyimino) -N -(pyridin-3-yl) acetamide derivatives in Swiss mice
    Kumar P, Swami D, Karade HN, Acharya J, Jatav PC, Kumar A, Meena MK
    Ref: Cellular & Molecular Biology (Noisy-le-grand), 60-3:53, 2014 : PubMed


    Title: Rosiglitazone Synergizes the Neuroprotective Effects of Valproic Acid Against Quinolinic Acid-Induced Neurotoxicity in Rats: Targeting PPARgamma and HDAC Pathways
    Mishra J, Chaudhary T, Kumar A
    Ref: Neurotox Res, 26:130, 2014 : PubMed


    Title: Implicating the role of lycopene in restoration of mitochondrial enzymes and BDNF levels in beta-amyloid induced Alzheimers disease
    Prakash A, Kumar A
    Ref: European Journal of Pharmacology, 741C:104, 2014 : PubMed


    Title: Modulation of nitrergic signalling pathway by American ginseng attenuates chronic unpredictable stress-induced cognitive impairment, neuroinflammation, and biochemical alterations
    Rinwa P, Kumar A
    Ref: Naunyn Schmiedebergs Arch Pharmacol, 387:129, 2014 : PubMed


    Title: Recent advances in industrial application of tannases: a review
    Beniwal V, Kumar A, Sharma J, Chhokar V
    Ref: Recent Pat Biotechnol, 7:228, 2013 : PubMed


    Title: Characterization of bud emergence 46 (BEM46) protein: Sequence, structural, phylogenetic and subcellular localization analyses
    Kumar A, Kollath-Leiss K, Kempken F
    Ref: Biochemical & Biophysical Research Communications, 438:526, 2013 : PubMed


    Title: Identification and characterisation of small-molecule inhibitors of Rv3097c-encoded lipase (LipY) of Mycobacterium tuberculosis that selectively inhibit growth of bacilli in hypoxia
    Saxena AK, Roy KK, Singh S, Vishnoi SP, Kumar A, Kashyap VK, Kremer L, Srivastava R, Srivastava BS
    Ref: Int J Antimicrob Agents, 42:27, 2013 : PubMed


    Title: The genome and development-dependent transcriptomes of Pyronema confluens: a window into fungal evolution
    Traeger S, Altegoer F, Freitag M, Gabaldon T, Kempken F, Kumar A, Marcet-Houben M, Poggeler S, Stajich JE, Nowrousian M
    Ref: PLoS Genet, 9:e1003820, 2013 : PubMed


    Title: Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury
    Gaur V, Kumar A
    Ref: Drug & Chemical Toxicology, 35:218, 2012 : PubMed


    Title: Whole-genome sequence of Corynebacterium pseudotuberculosis strain Cp162, isolated from camel
    Hassan SS, Schneider MP, Ramos RT, Carneiro AR, Ranieri A, Guimaraes LC, Ali A, Bakhtiar SM, Pereira Ude P and Silva A <23 more author(s)>
    Ref: Journal of Bacteriology, 194:5718, 2012 : PubMed


    Title: Exploring the role of BCHE in the onset of Diabetes, Obesity and Neurological Disorders
    Rao AA, Jyothsna G, Shalini P, Kumar A, Bhattacharya A, Kashyap A
    Ref: Bioinformation, 8:276, 2012 : PubMed


    Title: Piperine potentiates the protective effects of curcumin against chronic unpredictable stress-induced cognitive impairment and oxidative damage in mice
    Rinwa P, Kumar A
    Ref: Brain Research, 1488:38, 2012 : PubMed


    Title: Synthesis of ethyl ferulate in organic medium using celite-immobilized lipase
    Kumar A, Kanwar SS
    Ref: Bioresour Technol, 102:2162, 2011 : PubMed


    Title: Identification of variables and value optimization for optimum lipase production by Bacillus pumilus RK31 using statistical methodology
    Kumar R, Mahajan S, Kumar A, Singh D
    Ref: N Biotechnol, 28:65, 2011 : PubMed


    Title: Neuroprotective effect of carvedilol against aluminium induced toxicity: possible behavioral and biochemical alterations in rats
    Kumar A, Prakash A, Dogra S
    Ref: Pharmacol Rep, 63:915, 2011 : PubMed


    Title: A case of organophosphate poisoning presenting with seizure and unavailable history of parenteral suicide attempt
    Pandit V, Seshadri S, Rao SN, Samarasinghe C, Kumar A, Valsalan R
    Ref: J Emerg Trauma Shock, 4:132, 2011 : PubMed


    Title: The lin genes for gamma-hexachlorocyclohexane degradation in Sphingomonas sp. MM-1 proved to be dispersed across multiple plasmids
    Tabata M, Endo R, Ito M, Ohtsubo Y, Kumar A, Tsuda M, Nagata Y
    Ref: Biosci Biotechnol Biochem, 75:466, 2011 : PubMed


    Title: A novel amperometric biosensor based on single walled carbon nanotubes with acetylcholine esterase for the detection of carbaryl pesticide in water
    Firdoz S, Ma F, Yue X, Dai Z, Kumar A, Jiang B
    Ref: Talanta, 83:269, 2010 : PubMed


    Title: Protective effect of naringin, a citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats
    Kumar A, Dogra S, Prakash A
    Ref: J Med Food, 13:976, 2010 : PubMed


    Title: Response and recovery of acetylcholinesterase activity in freshwater shrimp, Paratya australiensis (Decapoda: Atyidae) exposed to selected anti-cholinesterase insecticides
    Kumar A, Doan H, Barnes M, Chapman JC, Kookana RS
    Ref: Ecotoxicology & Environmental Safety, 73:1503, 2010 : PubMed


    Title: Lipase-catalyzed production of a bioactive fatty amide derivative of 7,10-dihydroxy-8(E)-octadecenoic acid
    Khare SK, Kumar A, Kuo TM
    Ref: Bioresour Technol, 100:1482, 2009 : PubMed


    Title: Neuroprotective effect of carvedilol, an adrenergic antagonist against colchicine induced cognitive impairment and oxidative damage in rat
    Kumar A, Dogra S
    Ref: Pharmacol Biochem Behav, 92:25, 2009 : PubMed


    Title: Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations
    Kumar P, Kumar A
    Ref: European Journal of Pharmacology, 615:91, 2009 : PubMed


    Title: Protective role of sertraline against 3-nitropropionic acid-induced cognitive dysfunction and redox ratio in striatum, cortex and hippocampus of rat brain
    Kumar P, Kumar A
    Ref: Indian J Exp Biol, 47:715, 2009 : PubMed


    Title: Effect of N-acetyl cysteine against aluminium-induced cognitive dysfunction and oxidative damage in rats
    Prakash A, Kumar A
    Ref: Basic Clin Pharmacol Toxicol, 105:98, 2009 : PubMed


    Title: Effect of chronic treatment of carvedilol on oxidative stress in an intracerebroventricular streptozotocin induced model of dementia in rats
    Prakash AK, Kumar A
    Ref: J Pharm Pharmacol, 61:1665, 2009 : PubMed


    Title: Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2 .1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties
    Gao Y, Kuwabara H, Spivak CE, Xiao Y, Kellar K, Ravert HT, Kumar A, Alexander M, Hilton J and Horti AG <2 more author(s)>
    Ref: Journal of Medicinal Chemistry, 51:4751, 2008 : PubMed


    Title: Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer
    Jain M, Tilak AR, Upadhyay R, Kumar A, Mittal B
    Ref: Toxicol Appl Pharmacol, 230:247, 2008 : PubMed


    Title: Possible mechanism involved in sleep deprivation-induced memory dysfunction
    Kalonia H, Bishnoi M, Kumar A
    Ref: Methods Find Exp Clin Pharmacol, 30:529, 2008 : PubMed


    Title: Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon
    Kumar A, Deshane JS, Crossman DK, Bolisetty S, Yan BS, Kramnik I, Agarwal A, Steyn AJ
    Ref: Journal of Biological Chemistry, 283:18032, 2008 : PubMed


    Title: Protective effect of quercetin against ICV colchicine-induced cognitive dysfunctions and oxidative damage in rats
    Kumar A, Sehgal N, Kumar P, Padi SS, Naidu PS
    Ref: Phytother Res, 22:1563, 2008 : PubMed


    Title: Effect of curcumin on intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats
    Kumar A, Naidu PS, Seghal N, Padi SS
    Ref: J Med Food, 10:486, 2007 : PubMed


    Title: Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type
    Kumar A, Seghal N, Naidu PS, Padi SS, Goyal R
    Ref: Pharmacol Rep, 59:274, 2007 : PubMed


    Title: Role of combined administration of Tiron and glutathione against aluminum-induced oxidative stress in rat brain
    Sharma P, Ahmad Shah Z, Kumar A, Islam F, Mishra KP
    Ref: J Trace Elem Med Biol, 21:63, 2007 : PubMed


    Title: Selective loss of lin genes from hexachlorocyclohexane-degrading Pseudomonas aeruginosa ITRC-5 under different growth conditions
    Singh AK, Chaudhary P, Macwan AS, Diwedi UN, Kumar A
    Ref: Applied Microbiology & Biotechnology, 76:895, 2007 : PubMed


    Title: Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution
    Zubieta C, Krishna SS, McMullan D, Miller MD, Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL and Wilson IA <33 more author(s)>
    Ref: Proteins, 68:999, 2007 : PubMed


    Title: Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats
    Kumar A, Seghal N, Padi SV, Naidu PS
    Ref: European Journal of Pharmacology, 551:58, 2006 : PubMed


    Title: Cocrystallization of random copolymers of omega-pentadecalactone and epsilon-caprolactone synthesized by lipase catalysis
    Ceccorulli G, Scandola M, Kumar A, Kalra B, Gross RA
    Ref: Biomacromolecules, 6:902, 2005 : PubMed


    Title: Degradation of beta-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26
    Nagata Y, Prokop Z, Sato Y, Jerabek P, Kumar A, Ohtsubo Y, Tsuda M, Damborsky J
    Ref: Applied Environmental Microbiology, 71:2183, 2005 : PubMed


    Title: Role of piperonyl butoxide in the toxicity of chlorpyrifos to Ceriodaphnia dubia and Xenopus laevis
    El-Merhibi A, Kumar A, Smeaton T
    Ref: Ecotoxicology & Environmental Safety, 57:202, 2004 : PubMed


    Title: Imprinted mesodermal specific transcript (MEST) and H19 genes in renal development and diabetes
    Kanwar YS, Pan X, Lin S, Kumar A, Wada J, Haas CS, Liau G, Lomasney JW
    Ref: Kidney Int, 63:1658, 2003 : PubMed


    Title: Identification of developmentally regulated mesodermal-specific transcript in mouse embryonic metanephros
    Kanwar YS, Kumar A, Ota K, Lin S, Wada J, Chugh S, Wallner EI
    Ref: American Journal of Physiology Renal Physiol, 282:F953, 2002 : PubMed


    Title: Subcellular localization of the yeast proteome
    Kumar A, Agarwal S, Heyman JA, Matson S, Heidtman M, Piccirillo S, Umansky L, Drawid A, Jansen R and Snyder M <5 more author(s)>
    Ref: Genes Dev, 16:707, 2002 : PubMed


    Title: Acute toxicity of mixtures of chlorpyrifos, profenofos, and endosulfan to Ceriodaphnia dubia
    Woods M, Kumar A, Correll R
    Ref: Bulletin of Environmental Contamination & Toxicology, 68:801, 2002 : PubMed


    Title: Profenofos residues in wild fish from cotton-growing areas of New South Wales, Australia
    Kumar A, Chapman JC
    Ref: J Environ Qual, 30:740, 2001 : PubMed


    Title: Poly(3-hydroxybutyrate)-depolymerase from Pseudomonas lemoignei: catalysis of esterifications in organic media
    Kumar A, Gross RA, Jendrossek D
    Ref: J Org Chem, 65:7800, 2000 : PubMed


    Title: Candida antartica lipase B catalyzed polycaprolactone synthesis: effects of organic media and temperature
    Kumar A, Gross RA
    Ref: Biomacromolecules, 1:133, 2000 : PubMed


    Title: Systemic administration of defined extracts from Withania somnifera (Indian Ginseng) and Shilajit differentially affects cholinergic but not glutamatergic and GABAergic markers in rat brain
    Schliebs R, Liebmann A, Bhattacharya SK, Kumar A, Ghosal S, Bigl V
    Ref: Neurochem Int, 30:181, 1997 : PubMed


    Title: Development of laminar expression of the m2 muscarinic cholinergic receptor gene in rat visual cortex and the effect of monocular visual deprivation
    Rossner S, Kumar A, Witzemann V, Schliebs R
    Ref: Brain Research Developmental Brain Research, 77:55, 1994 : PubMed


    Title: Clinico-biochemical use of serum acetylcholine esterase following treatment with synthetic pyrethroids, cypermethrin and fenvalerate, in cattle and buffalo experimentally infested with Boophilus microplus
    Ansari MZ, Kumar A, Prasad RL, Basu A, Sahai BN, Sinha AP
    Ref: Indian J Exp Biol, 28:241, 1990 : PubMed


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